Evaluation of a Real-time Virtual Intervention to Empower Persons Living with HIV for Therapy Self-management: Study Protocol for an Online Randomized Controlled Trial. C�t�, J., Godin, G., Gu�h�neuc, Y., Rouleau, G., Ramirez-Garcia, P., Otis, J., Tremblay, C., & Fadel, G. Trials Journal (Trials), BioMed Central, December, 2012. 27 pages.
Evaluation of a Real-time Virtual Intervention to Empower Persons Living with HIV for Therapy Self-management: Study Protocol for an Online Randomized Controlled Trial [pdf]Paper  abstract   bibtex   
Morbidity and mortality among people infected with the human immunodeficiency virus (HIV) has declined dramatically since 1996 with the advent of a powerful antiretroviral therapy (ART) and the use of appropriate prophylaxis against opportunistic infections. Formerly considered a terminal illness, HIV infection is now categorized as a chronic disease. Though they cannot eradicate HIV, existing viral therapies suppress its replication and thus make it possible to maintain and improve the immune function of infected persons. However, therapy interruption, even if just temporary, allows the virus to multiply and then develop a resistance to medication. This is why it is imperative for therapy adherence to be optimal. Resistance reduces treatment response and allows the disease to progress. This resistance can be transmitted, thus becoming a public health issue. Developing interventions to boost and sustain antiretroviral therapy (ART) adherence has become a critical objective in the field of HIV and its treatment.

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