Coplanar and non-coplanar congener-specificity of PCB bioaccumulation and immunotoxicity in sea stars. Danis, B., Cattini, C., Teyssié, J., Villeneuve, J., Fowler, S., W., & Warnau, M. Aquatic toxicology (Amsterdam, Netherlands), 79(2):105-13, 8, 2006.
Coplanar and non-coplanar congener-specificity of PCB bioaccumulation and immunotoxicity in sea stars. [link]Website  abstract   bibtex   
The sea star Asterias rubens (L.), a representative species of the North Sea benthic environment, was exposed to a mixture of 10 selected PCB congeners (3 coplanar or c-PCBs, and 7 non-coplanar) via experimentally contaminated sediments. Both the degree of bioaccumulation and subsequent immunotoxic effects of these PCBs were determined. A strong congener-specificity for both bioaccumulation and immunotoxicity was found as well as a probable induction of a congener-specific detoxification mechanism resulting in the dramatic decrease in body levels of the three coplanar congeners tested (PCBs 77, 126 and 169). Moreover, a correlation was found between the bioaccumulation of c-PCBs and their immunotoxic effects. These findings suggest that coplanar congeners should be included in the list of congeners recommended to be analyzed for biological impact-oriented marine monitoring programmes.
@article{
 title = {Coplanar and non-coplanar congener-specificity of PCB bioaccumulation and immunotoxicity in sea stars.},
 type = {article},
 year = {2006},
 identifiers = {[object Object]},
 keywords = {Animals,Asterias,Asterias: chemistry,Asterias: drug effects,Asterias: immunology,Asterias: metabolism,Environmental Exposure,Geologic Sediments,Geologic Sediments: analysis,Kinetics,Polychlorinated Biphenyls,Polychlorinated Biphenyls: analysis,Polychlorinated Biphenyls: pharmacokinetics,Polychlorinated Biphenyls: toxicity,Reactive Oxygen Species,Reactive Oxygen Species: analysis,Statistics as Topic,Time Factors,Water Pollutants, Chemical,Water Pollutants, Chemical: analysis,Water Pollutants, Chemical: pharmacokinetics,Water Pollutants, Chemical: toxicity},
 pages = {105-13},
 volume = {79},
 websites = {http://dx.doi.org/10.1016/j.aquatox.2006.05.004},
 month = {8},
 id = {d11384b3-e3f5-342c-a3ff-6665acdb8ceb},
 created = {2010-09-15T11:26:04.000Z},
 accessed = {2010-09-15},
 file_attached = {false},
 profile_id = {c6c6f844-18d2-32db-a619-2e915134a952},
 last_modified = {2017-03-31T08:28:00.135Z},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {true},
 hidden = {false},
 citation_key = {Danis2006a},
 folder_uuids = {a6bf1321-9beb-4f7c-9715-6ab10e069d78,de387159-d9b2-4fc4-9f3e-bf2ab9b5879e},
 abstract = {The sea star Asterias rubens (L.), a representative species of the North Sea benthic environment, was exposed to a mixture of 10 selected PCB congeners (3 coplanar or c-PCBs, and 7 non-coplanar) via experimentally contaminated sediments. Both the degree of bioaccumulation and subsequent immunotoxic effects of these PCBs were determined. A strong congener-specificity for both bioaccumulation and immunotoxicity was found as well as a probable induction of a congener-specific detoxification mechanism resulting in the dramatic decrease in body levels of the three coplanar congeners tested (PCBs 77, 126 and 169). Moreover, a correlation was found between the bioaccumulation of c-PCBs and their immunotoxic effects. These findings suggest that coplanar congeners should be included in the list of congeners recommended to be analyzed for biological impact-oriented marine monitoring programmes.},
 bibtype = {article},
 author = {Danis, Bruno and Cattini, Chantal and Teyssié, Jean-Louis and Villeneuve, Jean-Pierre and Fowler, Scott W and Warnau, Michel},
 journal = {Aquatic toxicology (Amsterdam, Netherlands)},
 number = {2}
}

Downloads: 0