Mhp1, the Na⁺-Hydantoin Membrane Transport Protein. Jackson, S. M, Ivanova, E., Simmons, K., Patching, S. G, Weyand, S., Shimamura, T., Brückner, F., Iwata, S., Sharples, D. J, Baldwin, S. A, Sansom, M. P., Beckstein, O., Cameron, A. D, & Henderson, P. J. In Encylopedia of Biophysics, pages 1514–1521. Springer, Berlin, Heidelberg, 2013. ![Mhp1, the Na⁺-Hydantoin Membrane Transport Protein [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper abstract bibtex Mhp1 is a member of the Nucleobase-Cation-Symport-1 (NCS-1) family designated A.2.39.5 (Saier et al 2006, 2009; Ren and Paulsen, 2010), which carries out transport across membranes of hydantoins substituted with aromatic rings in the 5-position. The wild-type protein contains 489 amino acids (Suzuki and Henderson 2006), modestly modified in a genetic construct at the N-terminus and C-terminus, where a (His)6 tag is incorporated to facilitate amplified expression, purification and crystallisation (Suzuki and Henderson 2006; Shimamura et al, 2008). The transport reaction of Mhp1 is Hydantoin (out) + Na+ (out) –\textgreater Hydantoin (in) + Na+ (in) This reaction is of commercial interest, because of the potential for converting waste hydantoins to compounds of added value, for example L-amino acids (Suzuki et al 2005; Javier et al 2009).
@incollection{jackson_mhp1_2013,
address = {Berlin, Heidelberg},
title = {Mhp1, the {Na}⁺-{Hydantoin} {Membrane} {Transport} {Protein}},
isbn = {978-3-642-16711-9},
url = {https://doi.org/10.1007/978-3-642-16712-6_670},
abstract = {Mhp1 is a member of the Nucleobase-Cation-Symport-1 (NCS-1) family designated A.2.39.5 (Saier et al 2006, 2009; Ren and Paulsen, 2010), which carries out transport across membranes of hydantoins substituted with aromatic rings in the 5-position. The wild-type protein contains 489 amino acids (Suzuki and Henderson 2006), modestly modified in a genetic construct at the N-terminus and C-terminus, where a (His)6 tag is incorporated to facilitate amplified expression, purification and crystallisation (Suzuki and Henderson 2006; Shimamura et al, 2008). The transport reaction of Mhp1 is Hydantoin (out) + Na+ (out) –{\textgreater} Hydantoin (in) + Na+ (in) This reaction is of commercial interest, because of the potential for converting waste hydantoins to compounds of added value, for example L-amino acids (Suzuki et al 2005; Javier et al 2009).},
booktitle = {Encylopedia of {Biophysics}},
publisher = {Springer},
author = {Jackson, Scott M and Ivanova, Ekaterina and Simmons, Katie and Patching, Simon G and Weyand, Simone and Shimamura, Tatsuro and Brückner, Florian and Iwata, So and Sharples, David J and Baldwin, Stephen A and Sansom, Mark PS and Beckstein, Oliver and Cameron, Alexander D and Henderson, Peter JF},
editor = {Roberts, Gordon C. K.},
year = {2013},
pages = {1514--1521},
}
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J."],"year":2013,"bibtype":"incollection","biburl":"https://api.zotero.org/users/1446965/collections/GJIR5FQV/items?key=DK7eBbaofVxXe4ShaO2nLItp&format=bibtex&limit=100","bibdata":{"bibtype":"incollection","type":"incollection","address":"Berlin, Heidelberg","title":"Mhp1, the Na⁺-Hydantoin Membrane Transport Protein","isbn":"978-3-642-16711-9","url":"https://doi.org/10.1007/978-3-642-16712-6_670","abstract":"Mhp1 is a member of the Nucleobase-Cation-Symport-1 (NCS-1) family designated A.2.39.5 (Saier et al 2006, 2009; Ren and Paulsen, 2010), which carries out transport across membranes of hydantoins substituted with aromatic rings in the 5-position. The wild-type protein contains 489 amino acids (Suzuki and Henderson 2006), modestly modified in a genetic construct at the N-terminus and C-terminus, where a (His)6 tag is incorporated to facilitate amplified expression, purification and crystallisation (Suzuki and Henderson 2006; Shimamura et al, 2008). 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