@article{johansson_chronic_2022,
	title = {Chronic opioid use before and after exercise therapy and patient education among patients with knee or hip osteoarthritis},
	issn = {1063-4584},
	url = {https://www.sciencedirect.com/science/article/pii/S1063458422008032},
	doi = {10.1016/j.joca.2022.08.001},
	abstract = {Objective
To investigate changes in opioid use after supervised exercise therapy and patient education among knee or hip osteoarthritis patients with chronic opioid use.
Method
In this cohort study, we linked data from the Good Life with osteoArthritis in Denmark register (GLA:D®; standardised treatment program for osteoarthritis; January 2013 to November 2018) with national health registries. Among 35,549 patients, 1,262 were classified as chronic opioid users based on amount and temporal distribution of dispensed opioids the year before the intervention. We investigated changes in opioid use, measured as mg oral morphine equivalents (OMEQs), from the year before the intervention to the year after using generalized estimating equations.
Results
We found a 10\% decrease in mg OMEQs from the year before to the year after the intervention (incidence rate ratio [IRR]: 0.90, 95\% confidence interval [CI]: 0.86, 0.94). Additional analyses suggested this decrease to be mainly attributable to regulatory actions targeting opioid prescribing during the study period (IRR among patients participating in the intervention before: 0.98 [95\% CI: 0.89, 1.07] vs after: 0.83 [0.74, 0.93] regulatory actions). In a random general population sample of matched chronic opioid users, a similar opioid use pattern was observed over time, further supporting the impact of regulatory actions on the opioid use in the study population.
Conclusion
Among patients with knee or hip osteoarthritis and chronic opioid use, a standardised treatment program did not change opioid use when regulatory changes in opioid prescribing were taken into account.},
	language = {en},
	urldate = {2022-08-26},
	journal = {Osteoarthritis and Cartilage},
	author = {Johansson, M. S. and Pottegård, A. and Søndergaard, J. and Englund, M. and Grønne, D. T. and Skou, S. T. and Roos, E. M. and Thorlund, J. B.},
	month = aug,
	year = {2022},
	keywords = {Chronic opioid use, Deprescribing, Exercise therapy, Osteoarthritis, Patient education},
}

{"_id":"v7kGJzxEgpm8ZifBs","bibbaseid":"johansson-pottegrd-sndergaard-englund-grnne-skou-roos-thorlund-chronicopioidusebeforeandafterexercisetherapyandpatienteducationamongpatientswithkneeorhiposteoarthritis-2022","author_short":["Johansson, M. S.","Pottegård, A.","Søndergaard, J.","Englund, M.","Grønne, D. T.","Skou, S. T.","Roos, E. M.","Thorlund, J. B."],"bibdata":{"bibtype":"article","type":"article","title":"Chronic opioid use before and after exercise therapy and patient education among patients with knee or hip osteoarthritis","issn":"1063-4584","url":"https://www.sciencedirect.com/science/article/pii/S1063458422008032","doi":"10.1016/j.joca.2022.08.001","abstract":"Objective To investigate changes in opioid use after supervised exercise therapy and patient education among knee or hip osteoarthritis patients with chronic opioid use. Method In this cohort study, we linked data from the Good Life with osteoArthritis in Denmark register (GLA:D®; standardised treatment program for osteoarthritis; January 2013 to November 2018) with national health registries. Among 35,549 patients, 1,262 were classified as chronic opioid users based on amount and temporal distribution of dispensed opioids the year before the intervention. We investigated changes in opioid use, measured as mg oral morphine equivalents (OMEQs), from the year before the intervention to the year after using generalized estimating equations. Results We found a 10% decrease in mg OMEQs from the year before to the year after the intervention (incidence rate ratio [IRR]: 0.90, 95% confidence interval [CI]: 0.86, 0.94). Additional analyses suggested this decrease to be mainly attributable to regulatory actions targeting opioid prescribing during the study period (IRR among patients participating in the intervention before: 0.98 [95% CI: 0.89, 1.07] vs after: 0.83 [0.74, 0.93] regulatory actions). In a random general population sample of matched chronic opioid users, a similar opioid use pattern was observed over time, further supporting the impact of regulatory actions on the opioid use in the study population. Conclusion Among patients with knee or hip osteoarthritis and chronic opioid use, a standardised treatment program did not change opioid use when regulatory changes in opioid prescribing were taken into account.","language":"en","urldate":"2022-08-26","journal":"Osteoarthritis and Cartilage","author":[{"propositions":[],"lastnames":["Johansson"],"firstnames":["M.","S."],"suffixes":[]},{"propositions":[],"lastnames":["Pottegård"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Søndergaard"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Englund"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Grønne"],"firstnames":["D.","T."],"suffixes":[]},{"propositions":[],"lastnames":["Skou"],"firstnames":["S.","T."],"suffixes":[]},{"propositions":[],"lastnames":["Roos"],"firstnames":["E.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Thorlund"],"firstnames":["J.","B."],"suffixes":[]}],"month":"August","year":"2022","keywords":"Chronic opioid use, Deprescribing, Exercise therapy, Osteoarthritis, Patient education","bibtex":"@article{johansson_chronic_2022,\n\ttitle = {Chronic opioid use before and after exercise therapy and patient education among patients with knee or hip osteoarthritis},\n\tissn = {1063-4584},\n\turl = {https://www.sciencedirect.com/science/article/pii/S1063458422008032},\n\tdoi = {10.1016/j.joca.2022.08.001},\n\tabstract = {Objective\nTo investigate changes in opioid use after supervised exercise therapy and patient education among knee or hip osteoarthritis patients with chronic opioid use.\nMethod\nIn this cohort study, we linked data from the Good Life with osteoArthritis in Denmark register (GLA:D®; standardised treatment program for osteoarthritis; January 2013 to November 2018) with national health registries. Among 35,549 patients, 1,262 were classified as chronic opioid users based on amount and temporal distribution of dispensed opioids the year before the intervention. We investigated changes in opioid use, measured as mg oral morphine equivalents (OMEQs), from the year before the intervention to the year after using generalized estimating equations.\nResults\nWe found a 10\\% decrease in mg OMEQs from the year before to the year after the intervention (incidence rate ratio [IRR]: 0.90, 95\\% confidence interval [CI]: 0.86, 0.94). Additional analyses suggested this decrease to be mainly attributable to regulatory actions targeting opioid prescribing during the study period (IRR among patients participating in the intervention before: 0.98 [95\\% CI: 0.89, 1.07] vs after: 0.83 [0.74, 0.93] regulatory actions). In a random general population sample of matched chronic opioid users, a similar opioid use pattern was observed over time, further supporting the impact of regulatory actions on the opioid use in the study population.\nConclusion\nAmong patients with knee or hip osteoarthritis and chronic opioid use, a standardised treatment program did not change opioid use when regulatory changes in opioid prescribing were taken into account.},\n\tlanguage = {en},\n\turldate = {2022-08-26},\n\tjournal = {Osteoarthritis and Cartilage},\n\tauthor = {Johansson, M. S. and Pottegård, A. and Søndergaard, J. and Englund, M. and Grønne, D. T. and Skou, S. T. and Roos, E. M. and Thorlund, J. B.},\n\tmonth = aug,\n\tyear = {2022},\n\tkeywords = {Chronic opioid use, Deprescribing, Exercise therapy, Osteoarthritis, Patient education},\n}\n\n","author_short":["Johansson, M. S.","Pottegård, A.","Søndergaard, J.","Englund, M.","Grønne, D. T.","Skou, S. T.","Roos, E. M.","Thorlund, J. B."],"key":"johansson_chronic_2022","id":"johansson_chronic_2022","bibbaseid":"johansson-pottegrd-sndergaard-englund-grnne-skou-roos-thorlund-chronicopioidusebeforeandafterexercisetherapyandpatienteducationamongpatientswithkneeorhiposteoarthritis-2022","role":"author","urls":{"Paper":"https://www.sciencedirect.com/science/article/pii/S1063458422008032"},"keyword":["Chronic opioid use","Deprescribing","Exercise therapy","Osteoarthritis","Patient education"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://api.zotero.org/groups/5155143/items?key=IVTAjWy1U5EkGJqE2Z2qQCfh&format=bibtex&limit=100","dataSources":["7PYyrRz6AvkoBBchz","NGDbv8dMYDaDn8kqm","5jEuhQhgRx3py8LmG","LPTeGao77ndnG4Tks"],"keywords":["chronic opioid use","deprescribing","exercise therapy","osteoarthritis","patient education"],"search_terms":["chronic","opioid","use","before","exercise","therapy","patient","education","patients","knee","hip","osteoarthritis","johansson","pottegård","søndergaard","englund","grønne","skou","roos","thorlund"],"title":"Chronic opioid use before and after exercise therapy and patient education among patients with knee or hip osteoarthritis","year":2022}