Change in patient-reported outcomes in patients with and without mechanical symptoms undergoing arthroscopic meniscal surgery: A prospective cohort study. Pihl, K., Turkiewicz, A., Englund, M., Stefan Lohmander, L., Jørgensen, U., Nissen, N., Schjerning, J., & Thorlund, J. B. Osteoarthritis and Cartilage, 26(8):1008–1016, August, 2018.
Change in patient-reported outcomes in patients with and without mechanical symptoms undergoing arthroscopic meniscal surgery: A prospective cohort study [link]Paper  doi  abstract   bibtex   
OBJECTIVE: Patients with degenerative or traumatic meniscal tears are at high risk of developing knee osteoarthritis. We investigated if younger (≤40 years) and older (\textgreater40 years) patients with preoperative mechanical symptoms improved more in patient-reported outcomes after meniscal surgery than those without mechanical symptoms. DESIGN: Patients from Knee Arthroscopy Cohort Southern Denmark (KACS) undergoing arthroscopic surgery for a meniscal tear completed online questionnaires before surgery, and at 12 and 52 weeks follow-up. Questionnaires included self-reported presence of mechanical symptoms (i.e. sensation of catching and/or locking) and the Knee Injury and Osteoarthritis Outcome Score (KOOS). We analyzed between-group differences in change in KOOS4 from baseline to 52 weeks, using an adjusted mixed linear model. RESULTS: 150 younger patients (mean age 31 (SD 7), 67% men) and 491 older patients (mean age 54 (SD 9), 53% men) constituted the baseline cohorts. Patients with mechanical symptoms generally had worse self-reported outcomes before surgery. At 52 weeks follow-up, younger patients with preoperative mechanical symptoms had improved more in KOOS4 scores than younger patients without preoperative mechanical symptoms (adjusted mean difference 10.5, 95%CI: 4.3, 16.6), but did not exceed the absolute postoperative KOOS4 scores observed for those without mechanical symptoms. No difference in improvement was observed between older patients with or without mechanical symptoms (adjusted mean difference 0.7, 95%CI: -2.6, 3.9). CONCLUSIONS: Younger patients (≤40 years) with preoperative mechanical symptoms experienced greater improvements after arthroscopic surgery compared to younger patients without mechanical symptoms. Our observational study result needs to be confirmed in randomized trials.
@article{pihl_change_2018,
	title = {Change in patient-reported outcomes in patients with and without mechanical symptoms undergoing arthroscopic meniscal surgery: {A} prospective cohort study},
	volume = {26},
	issn = {1522-9653},
	shorttitle = {Change in patient-reported outcomes in patients with and without mechanical symptoms undergoing arthroscopic meniscal surgery},
	url = {https://doi.org/10.1016%2Fj.joca.2018.05.004},
	doi = {10.1016/j.joca.2018.05.004},
	abstract = {OBJECTIVE: Patients with degenerative or traumatic meniscal tears are at high risk of developing knee osteoarthritis. We investigated if younger (≤40 years) and older ({\textgreater}40 years) patients with preoperative mechanical symptoms improved more in patient-reported outcomes after meniscal surgery than those without mechanical symptoms.
DESIGN: Patients from Knee Arthroscopy Cohort Southern Denmark (KACS) undergoing arthroscopic surgery for a meniscal tear completed online questionnaires before surgery, and at 12 and 52 weeks follow-up. Questionnaires included self-reported presence of mechanical symptoms (i.e. sensation of catching and/or locking) and the Knee Injury and Osteoarthritis Outcome Score (KOOS). We analyzed between-group differences in change in KOOS4 from baseline to 52 weeks, using an adjusted mixed linear model.
RESULTS: 150 younger patients (mean age 31 (SD 7), 67\% men) and 491 older patients (mean age 54 (SD 9), 53\% men) constituted the baseline cohorts. Patients with mechanical symptoms generally had worse self-reported outcomes before surgery. At 52 weeks follow-up, younger patients with preoperative mechanical symptoms had improved more in KOOS4 scores than younger patients without preoperative mechanical symptoms (adjusted mean difference 10.5, 95\%CI: 4.3, 16.6), but did not exceed the absolute postoperative KOOS4 scores observed for those without mechanical symptoms. No difference in improvement was observed between older patients with or without mechanical symptoms (adjusted mean difference 0.7, 95\%CI: -2.6, 3.9).
CONCLUSIONS: Younger patients (≤40 years) with preoperative mechanical symptoms experienced greater improvements after arthroscopic surgery compared to younger patients without mechanical symptoms. Our observational study result needs to be confirmed in randomized trials.},
	language = {eng},
	number = {8},
	journal = {Osteoarthritis and Cartilage},
	author = {Pihl, Kenneth and Turkiewicz, Aleksandra and Englund, Martin and Stefan Lohmander, L. and Jørgensen, Uffe and Nissen, Nis and Schjerning, Jeppe and Thorlund, Jonas B.},
	month = aug,
	year = {2018},
	pmid = {29792925},
	keywords = {Arthroscopy, Knee, Mechanical symptoms, Meniscal tears, Osteoarthritis, Patient-reported outcomes, knee, mechanical symptoms, meniscal tears, osteoarthritis, patient-reported outcomes},
	pages = {1008--1016},
}

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