The prevalence of primary angle closure glaucoma in European derived populations: A systematic review. Day, A, Bunce, C, Foster, P, Gazzard, G, Baio, G, Azuara-Blanco, A, Munoz, B, & Friedman, D British Journal of Ophthalmology, 96(9):1162-1167, Sep, 2012.
doi  abstract   bibtex   
Aim: To estimate the prevalence of primary angle closure glaucoma (PACG) in European derived populations. Method: Systematic review and modelling of PACG prevalence data from population studies. PACG was defined according to the ISGEO definition requiring structural and/or functional evidence of glaucomatous optic neuropathy. Prevalence estimates were applied to the 2010 United Nations projected population figures to estimate case numbers. Results: The prevalence of PACG in those 40 years or more is 0.4% (95% CI 0.3% to 0.5%). Age-specific prevalence values are 0.02% (CI 0.00 to 0.08) for those 40-49 years, 0.60% (0.27 to 1.00) for those 50-59 years, 0.20% (0.06 to 0.42) for those 60-69 years and 0.94% (0.63 to 1.35) for those 70 years and older. Three-quarters of all cases occur in female subjects (3.25 female to 1 male; CI 1.76 to 5.94). Conclusion: This analysis provides a current evidence-based estimate of PACG prevalence in European derived populations and suggests there are 130 000 people in the UK, 1.60 million people in Europe and 581 000 people in the USA with PACG today. Accounting for ageing population structures, cases are predicted to increase by 19% in the UK, 9% in Europe and 18% in the USA within the next decade. PACG is more common than previously thought, and all primary glaucoma cases should be considered to be PACG until the anterior chamber angle is shown to be open on gonioscopy.
@ARTICLE{Dayetal:2012,
  author = {Day, A and Bunce, C and Foster, P and Gazzard, G and Baio, G and
	Azuara-Blanco, A and Munoz, B and Friedman, D},
  title = {{The prevalence of primary angle closure glaucoma in European derived populations: A systematic review}},
  journal = {British Journal of Ophthalmology},
  year = {2012},
  volume = {96},
  pages = {1162-1167},
  month = {Sep},
  abstract = {Aim: To estimate the prevalence of primary angle closure glaucoma
	(PACG) in European derived populations. Method: Systematic review
	and modelling of PACG prevalence data from population studies. PACG
	was defined according to the ISGEO definition requiring structural
	and/or functional evidence of glaucomatous optic neuropathy. Prevalence
	estimates were applied to the 2010 United Nations projected population
	figures to estimate case numbers. Results: The prevalence of PACG
	in those 40 years or more is 0.4% (95% CI 0.3% to 0.5%). Age-specific
	prevalence values are 0.02% (CI 0.00 to 0.08) for those 40-49 years,
	0.60% (0.27 to 1.00) for those 50-59 years, 0.20% (0.06 to 0.42)
	for those 60-69 years and 0.94% (0.63 to 1.35) for those 70 years
	and older. Three-quarters of all cases occur in female subjects (3.25
	female to 1 male; CI 1.76 to 5.94). Conclusion: This analysis provides
	a current evidence-based estimate of PACG prevalence in European
	derived populations and suggests there are 130 000 people in the
	UK, 1.60 million people in Europe and 581 000 people in the USA with
	PACG today. Accounting for ageing population structures, cases are
	predicted to increase by 19% in the UK, 9% in Europe and 18% in the
	USA within the next decade. PACG is more common than previously thought,
	and all primary glaucoma cases should be considered to be PACG until
	the anterior chamber angle is shown to be open on gonioscopy.},
  doi = {10.1136/bjophthalmol-2011-301189},
  eissn = {1468-2079},
  issn = {0007-1161},
  number = {9}
}

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