Guidelines for imaging retinoblastoma: imaging principles and MRI standardization. de Graaf, P., Goricke, S., Rodjan, F., Galluzzi, P., Maeder, P., Castelijns, J. A., & Brisse, H. J. Pediatric Radiology, 42(1):2--14, January, 2012.
Guidelines for imaging retinoblastoma: imaging principles and MRI standardization [link]Paper  doi  abstract   bibtex   
Retinoblastoma is the most common intraocular tumor in children. The diagnosis is usually established by the ophthalmologist on the basis of fundoscopy and US. Together with US, high-resolution MRI has emerged as an important imaging modality for pretreatment assessment, i.e. for diagnostic confirmation, detection of local tumor extent, detection of associated developmental malformation of the brain and detection of associated intracranial primitive neuroectodermal tumor (trilateral retinoblastoma). Minimum requirements for pretreatment diagnostic evaluation of retinoblastoma or mimicking lesions are presented, based on consensus among members of the European Retinoblastoma Imaging Collaboration (ERIC). The most appropriate techniques for imaging in a child with leukocoria are reviewed. CT is no longer recommended. Implementation of a standardized MRI protocol for retinoblastoma in clinical practice may benefit children worldwide, especially those with hereditary retinoblastoma, since a decreased use of CT reduces the exposure to ionizing radiation.
@article{de_graaf_guidelines_2012,
	title = {Guidelines for imaging retinoblastoma: imaging principles and {MRI} standardization},
	volume = {42},
	issn = {0301-0449},
	shorttitle = {Guidelines for imaging retinoblastoma},
	url = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256324/},
	doi = {10.1007/s00247-011-2201-5},
	abstract = {Retinoblastoma is the most common intraocular tumor in children. The diagnosis is usually established by the ophthalmologist on the basis of fundoscopy and US. Together with US, high-resolution MRI has emerged as an important imaging modality for pretreatment assessment, i.e. for diagnostic confirmation, detection of local tumor extent, detection of associated developmental malformation of the brain and detection of associated intracranial primitive neuroectodermal tumor (trilateral retinoblastoma). Minimum requirements for pretreatment diagnostic evaluation of retinoblastoma or mimicking lesions are presented, based on consensus among members of the European Retinoblastoma Imaging Collaboration (ERIC). The most appropriate techniques for imaging in a child with leukocoria are reviewed. CT is no longer recommended. Implementation of a standardized MRI protocol for retinoblastoma in clinical practice may benefit children worldwide, especially those with hereditary retinoblastoma, since a decreased use of CT reduces the exposure to ionizing radiation.},
	number = {1},
	urldate = {2014-08-07TZ},
	journal = {Pediatric Radiology},
	author = {de Graaf, Pim and Goricke, Sophia and Rodjan, Firazia and Galluzzi, Paolo and Maeder, Philippe and Castelijns, Jonas A. and Brisse, Herve J.},
	month = jan,
	year = {2012},
	pmid = {21850471},
	pmcid = {PMC3256324},
	pages = {2--14}
}

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