Neuron-Semiconductor Chip with Chemical Synapse between Identified Neurons. Kaul, R. A.; Syed, N. I.; and Fromherz, P. Physical Review Letters, 92(3):038102, APS, jan, 2004.
Neuron-Semiconductor Chip with Chemical Synapse between Identified Neurons [link]Paper  doi  abstract   bibtex   
Noninvasive electrical stimulation and recording of neuronal networks from semiconductor chips is a prerequisite for the development of neuroelectronic devices. In a proof-of-principle experiment, we implemented the fundamental element of such future hybrids by joining a silicon chip with an excitatory chemical synapse between a pair of identified neurons from the pond snail. We stimulated the presynaptic cell (VD4) with a chip capacitor and recorded the activity of the postsynaptic cell (LPeD1) with a transistor. We enhanced the strength of the soma-soma synapse by repetitive capacitor stimulation, establishing a neuronal memory on the silicon chip.
@article{pop00427,
abstract = {Noninvasive electrical stimulation and recording of neuronal networks from semiconductor chips is a prerequisite for the development of neuroelectronic devices. In a proof-of-principle experiment, we implemented the fundamental element of such future hybrids by joining a silicon chip with an excitatory chemical synapse between a pair of identified neurons from the pond snail. We stimulated the presynaptic cell (VD4) with a chip capacitor and recorded the activity of the postsynaptic cell (LPeD1) with a transistor. We enhanced the strength of the soma-soma synapse by repetitive capacitor stimulation, establishing a neuronal memory on the silicon chip.},
annote = {Query date: 2020-06-29 13:05:30},
author = {Kaul, R. Alexander and Syed, Naweed I. and Fromherz, Peter},
doi = {10.1103/PhysRevLett.92.038102},
issn = {0031-9007},
journal = {Physical Review Letters},
month = {jan},
number = {3},
pages = {038102},
publisher = {APS},
title = {{Neuron-Semiconductor Chip with Chemical Synapse between Identified Neurons}},
url = {https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.92.038102 https://link.aps.org/doi/10.1103/PhysRevLett.92.038102},
volume = {92},
year = {2004}
}
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