In vivo diffusion tensor imaging of the human calf muscle. Sinha, S., Sinha, U., & Edgerton, V. R. Journal of Magnetic Resonance Imaging, 24(1):182--190, July, 2006. 00000
In vivo diffusion tensor imaging of the human calf muscle [link]Paper  doi  abstract   bibtex   
Purpose To demonstrate the feasibility of in vivo calf muscle fiber tracking in human subjects. Materials and Methods An EPI-based diffusion tensor imaging (DTI) sequence with six-direction diffusion gradient sensitization was implemented, and DT images were acquired at 3 Tesla on five subjects using an extremity coil. The mean diffusivity, fractional anisotropy (FA), and fiber angle (with respect to the magnet z-axis) were measured in different muscles, and fibers were tracked from several regions of interest (ROIs). Results The fiber orientations in the current DTI studies agree well with those determined in previous spectroscopic studies. The orientation angles ranged from 13.4° in the lateral gastrocnemius to 48.5° in the medial soleus. The diffusion ellipsoid in muscle tissue is anisotropic and approximates a prolate model, as shown by color maps of the anisotropy. Fibers were tracked from the different muscle regions, and the unipennate and bipennate structure of muscle fibers was visualized. Conclusion The study clearly shows that in vivo fiber tracking of muscle fibers is feasible and could potentially be applied to study muscle structure function relationships. J. Magn. Reson. Imaging 2006. © 2006 Wiley-Liss, Inc.
@article{sinha_vivo_2006,
	title = {In vivo diffusion tensor imaging of the human calf muscle},
	volume = {24},
	copyright = {Copyright © 2006 Wiley-Liss, Inc.},
	issn = {1522-2586},
	url = {http://proxy.library.upenn.edu:2077/doi/10.1002/jmri.20593/abstract},
	doi = {10.1002/jmri.20593},
	abstract = {Purpose
To demonstrate the feasibility of in vivo calf muscle fiber tracking in human subjects.
Materials and Methods
An EPI-based diffusion tensor imaging (DTI) sequence with six-direction diffusion gradient sensitization was implemented, and DT images were acquired at 3 Tesla on five subjects using an extremity coil. The mean diffusivity, fractional anisotropy (FA), and fiber angle (with respect to the magnet z-axis) were measured in different muscles, and fibers were tracked from several regions of interest (ROIs).
Results
The fiber orientations in the current DTI studies agree well with those determined in previous spectroscopic studies. The orientation angles ranged from 13.4° in the lateral gastrocnemius to 48.5° in the medial soleus. The diffusion ellipsoid in muscle tissue is anisotropic and approximates a prolate model, as shown by color maps of the anisotropy. Fibers were tracked from the different muscle regions, and the unipennate and bipennate structure of muscle fibers was visualized.
Conclusion
The study clearly shows that in vivo fiber tracking of muscle fibers is feasible and could potentially be applied to study muscle structure function relationships. J. Magn. Reson. Imaging 2006. © 2006 Wiley-Liss, Inc.},
	language = {en},
	number = {1},
	urldate = {2014-09-02TZ},
	journal = {Journal of Magnetic Resonance Imaging},
	author = {Sinha, Shantanu and Sinha, Usha and Edgerton, V. Reggie},
	month = jul,
	year = {2006},
	note = {00000},
	keywords = {3T in vivo muscle DTI, EPI diffusion imaging, diffusion anisotropy, fiber orientation, muscle diffusion anisotropy, muscle diffusion tensor imaging, muscle diffusion trace, muscle fiber orientation, muscle fiber tracts, tetrahedral encoded diffusion},
	pages = {182--190}
}

Downloads: 0