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\n  \n 2020\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n \n Intravital optoacoustic and ultrasound bio-microscopy reveal radiation-inhibited skull angiogenesis.\n \n \n \n \n\n\n \n Estrada, H.; Rebling, J.; Sievert, W.; Hladik, D.; Hofmann, U.; Gottschalk, S.; Tapio, S.; Multhoff, G.; and Razansky, D.\n\n\n \n\n\n\n Bone, 133(October 2019). 2020.\n \n\n\n\n
\n\n\n\n \n \n \"IntravitalPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
\n 
@article{\n title = {Intravital optoacoustic and ultrasound bio-microscopy reveal radiation-inhibited skull angiogenesis},\n type = {article},\n year = {2020},\n keywords = {Bone angiogenesis,Image segmentation,Optoacoustic microscopy,Quantitative vasculature analysis,Radiation,Skull vasculature,Ultrasound microscopy},\n volume = {133},\n id = {dd04941c-3f70-3c65-959f-0451a6515fad},\n created = {2020-07-11T11:23:46.414Z},\n file_attached = {true},\n profile_id = {324e2dd8-ad33-3b22-a1f1-eb499a0e8419},\n group_id = {9be6478b-54cd-3713-9237-f1e3cf6da833},\n last_modified = {2020-07-18T08:43:14.406Z},\n read = {true},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Estrada2020},\n private_publication = {false},\n abstract = {Angiogenesis is critical in bone development and growth. Dense, large-scale, and multi-layered vascular networks formed by thin-walled sinusoidal vessels perfuse the plate bones and play an important role in bone repair. Yet, the intricate functional morphology of skull microvasculature remains poorly understood as it is difficult to visualize using existing intravital microscopy techniques. Here we introduced an intravital, fully-transcranial imaging approach based on hybrid optoacoustic and ultrasound bio-microscopy for large-scale observations and quantitative analysis of the vascular morphology, angiogenesis, vessel remodeling, and subsurface roughness in murine skulls. Our approach revealed radiation-inhibited angiogenesis in the skull bone. We also observed previously undocumented sinusoidal vascular networks spanning the entire skullcap, thus opening new vistas for studying the complex interactions between calvarial, pial, and cortical vascular systems.},\n bibtype = {article},\n author = {Estrada, Héctor and Rebling, Johannes and Sievert, Wolfgang and Hladik, Daniela and Hofmann, Urs and Gottschalk, Sven and Tapio, Soile and Multhoff, Gabriele and Razansky, Daniel},\n doi = {10.1016/j.bone.2020.115251},\n journal = {Bone},\n number = {October 2019}\n}
\n
\n\n\n
\n Angiogenesis is critical in bone development and growth. Dense, large-scale, and multi-layered vascular networks formed by thin-walled sinusoidal vessels perfuse the plate bones and play an important role in bone repair. Yet, the intricate functional morphology of skull microvasculature remains poorly understood as it is difficult to visualize using existing intravital microscopy techniques. Here we introduced an intravital, fully-transcranial imaging approach based on hybrid optoacoustic and ultrasound bio-microscopy for large-scale observations and quantitative analysis of the vascular morphology, angiogenesis, vessel remodeling, and subsurface roughness in murine skulls. Our approach revealed radiation-inhibited angiogenesis in the skull bone. We also observed previously undocumented sinusoidal vascular networks spanning the entire skullcap, thus opening new vistas for studying the complex interactions between calvarial, pial, and cortical vascular systems.\n
\n\n\n
\n\n\n\n\n\n
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\n
\n  \n 2019\n \n \n (1)\n \n \n
\n
\n \n \n
\n \n\n \n \n \n \n \n \n Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain.\n \n \n \n \n\n\n \n Gottschalk, S.; Degtyaruk, O.; Mc Larney, B.; Rebling, J.; Hutter, M., A.; Deán-Ben, X., L.; Shoham, S.; and Razansky, D.\n\n\n \n\n\n\n Nature Biomedical Engineering, 3(5): 392-401. 3 2019.\n \n\n\n\n
\n\n\n\n \n \n \"RapidWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n \n \n\n\n\n
\n 
@article{\n title = {Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain},\n type = {article},\n year = {2019},\n keywords = {Imaging,Imaging and sensing,Neuroscience,Sensors and probes},\n pages = {392-401},\n volume = {3},\n websites = {http://www.nature.com/articles/s41551-019-0372-9,http://dx.doi.org/10.1038/s41551-019-0372-9},\n month = {3},\n publisher = {Springer US},\n day = {25},\n id = {acc7a159-f20c-30a0-afa5-f5091da6d8a0},\n created = {2020-07-18T08:43:14.059Z},\n accessed = {2019-04-02},\n file_attached = {false},\n profile_id = {324e2dd8-ad33-3b22-a1f1-eb499a0e8419},\n group_id = {9be6478b-54cd-3713-9237-f1e3cf6da833},\n last_modified = {2020-07-18T08:43:14.059Z},\n read = {true},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Gottschalk2019},\n private_publication = {false},\n abstract = {Efforts to scale neuroimaging towards the direct visualization of mammalian brain-wide neuronal activity have faced major challenges. Although high-resolution optical imaging of the whole brain in small animals has been achieved ex vivo, the real-time and direct monitoring of large-scale neuronal activity remains difficult, owing to the performance gap between localized, largely invasive, optical microscopy of rapid, cellular-resolved neuronal activity and whole-brain macroscopy of slow haemodynamics and metabolism. Here, we demonstrate both ex vivo and non-invasive in vivo functional optoacoustic (OA) neuroimaging of mice expressing the genetically encoded calcium indicator GCaMP6f. The approach offers rapid, high-resolution three-dimensional snapshots of whole-brain neuronal activity maps using single OA excitations, and of stimulus-evoked slow haemodynamics and fast calcium activity in the presence of strong haemoglobin background absorption. By providing direct neuroimaging at depths and spatiotemporal resolutions superior to optical fluorescence imaging, functional OA neuroimaging bridges the gap between functional microscopy and whole-brain macroscopy.},\n bibtype = {article},\n author = {Gottschalk, Sven and Degtyaruk, Oleksiy and Mc Larney, Benedict and Rebling, Johannes and Hutter, Magdalena Anastasia and Deán-Ben, Xosé Luís and Shoham, Shy and Razansky, Daniel},\n doi = {10.1038/s41551-019-0372-9},\n journal = {Nature Biomedical Engineering},\n number = {5}\n}
\n
\n\n\n
\n Efforts to scale neuroimaging towards the direct visualization of mammalian brain-wide neuronal activity have faced major challenges. Although high-resolution optical imaging of the whole brain in small animals has been achieved ex vivo, the real-time and direct monitoring of large-scale neuronal activity remains difficult, owing to the performance gap between localized, largely invasive, optical microscopy of rapid, cellular-resolved neuronal activity and whole-brain macroscopy of slow haemodynamics and metabolism. Here, we demonstrate both ex vivo and non-invasive in vivo functional optoacoustic (OA) neuroimaging of mice expressing the genetically encoded calcium indicator GCaMP6f. The approach offers rapid, high-resolution three-dimensional snapshots of whole-brain neuronal activity maps using single OA excitations, and of stimulus-evoked slow haemodynamics and fast calcium activity in the presence of strong haemoglobin background absorption. By providing direct neuroimaging at depths and spatiotemporal resolutions superior to optical fluorescence imaging, functional OA neuroimaging bridges the gap between functional microscopy and whole-brain macroscopy.\n
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\n
\n  \n 2018\n \n \n (2)\n \n \n
\n
\n \n \n
\n \n\n \n \n \n \n \n \n Dual-wavelength hybrid optoacoustic-ultrasound biomicroscopy for functional imaging of large-scale cerebral vascular networks.\n \n \n \n \n\n\n \n Rebling, J.; Estrada, H.; Gottschalk, S.; Sela, G.; Zwack, M.; Wissmeyer, G.; Ntziachristos, V.; and Razansky, D.\n\n\n \n\n\n\n Journal of Biophotonics, 11(9): e201800057. 9 2018.\n \n\n\n\n
\n\n\n\n \n \n \"Dual-wavelengthPaper\n  \n \n \n \"Dual-wavelengthWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
\n 
@article{\n title = {Dual-wavelength hybrid optoacoustic-ultrasound biomicroscopy for functional imaging of large-scale cerebral vascular networks},\n type = {article},\n year = {2018},\n keywords = {blood vessels,brain,cerebral,microscopy,photoacoustics,ultrasound},\n pages = {e201800057},\n volume = {11},\n websites = {http://doi.wiley.com/10.1002/jbio.201800057},\n month = {9},\n id = {f23e0733-7bd7-319f-acf3-512fbf13fbdf},\n created = {2020-07-11T11:23:46.153Z},\n file_attached = {true},\n profile_id = {324e2dd8-ad33-3b22-a1f1-eb499a0e8419},\n group_id = {9be6478b-54cd-3713-9237-f1e3cf6da833},\n last_modified = {2020-07-18T08:43:14.309Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Rebling2018},\n private_publication = {false},\n abstract = {A critical link exists between pathological changes of cerebral vasculature and diseases affecting brain function. Microscopic techniques have played an indispensable role in the study of neurovascular anatomy and functions. Yet, investigations are often hindered by suboptimal trade-offs between the spatiotemporal resolution, field-of-view (FOV) and type of contrast offered by the existing optical microscopy techniques. We present a hybrid dual-wavelength optoacoustic (OA) biomicroscope capable of rapid transcranial visualization of large-scale cerebral vascular networks. The system offers 3-dimensional views of the morphology and oxygenation status of the cerebral vasculature with single capillary resolution and a FOV exceeding 6 × 8 mm2, thus covering the entire cortical vasculature in mice. The large-scale OA imaging capacity is complemented by simultaneously acquired pulse-echo ultrasound (US) biomicroscopy scans of the mouse skull. The new approach holds great potential to provide better insights into cerebrovascular function and facilitate efficient studies into neurological and vascular abnormalities of the brain.},\n bibtype = {article},\n author = {Rebling, Johannes and Estrada, Héctor and Gottschalk, Sven and Sela, Gali and Zwack, Michael and Wissmeyer, Georg and Ntziachristos, Vasilis and Razansky, Daniel},\n doi = {10.1002/jbio.201800057},\n journal = {Journal of Biophotonics},\n number = {9}\n}
\n
\n\n\n
\n A critical link exists between pathological changes of cerebral vasculature and diseases affecting brain function. Microscopic techniques have played an indispensable role in the study of neurovascular anatomy and functions. Yet, investigations are often hindered by suboptimal trade-offs between the spatiotemporal resolution, field-of-view (FOV) and type of contrast offered by the existing optical microscopy techniques. We present a hybrid dual-wavelength optoacoustic (OA) biomicroscope capable of rapid transcranial visualization of large-scale cerebral vascular networks. The system offers 3-dimensional views of the morphology and oxygenation status of the cerebral vasculature with single capillary resolution and a FOV exceeding 6 × 8 mm2, thus covering the entire cortical vasculature in mice. The large-scale OA imaging capacity is complemented by simultaneously acquired pulse-echo ultrasound (US) biomicroscopy scans of the mouse skull. The new approach holds great potential to provide better insights into cerebrovascular function and facilitate efficient studies into neurological and vascular abnormalities of the brain.\n
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\n \n\n \n \n \n \n \n \n Integrated catheter for simultaneous radio frequency ablation and optoacoustic monitoring of lesion progression.\n \n \n \n \n\n\n \n Rebling, J.; Oyaga Landa, F., J.; Deán-Ben, X., L.; Douplik, A.; and Razansky, D.\n\n\n \n\n\n\n Optics Letters, 43(8): 1886. 2018.\n \n\n\n\n
\n\n\n\n \n \n \"IntegratedPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n 
@article{\n title = {Integrated catheter for simultaneous radio frequency ablation and optoacoustic monitoring of lesion progression},\n type = {article},\n year = {2018},\n pages = {1886},\n volume = {43},\n id = {4b164390-a608-3d95-bb00-6dacdabea8b8},\n created = {2020-07-11T11:23:46.426Z},\n file_attached = {true},\n profile_id = {324e2dd8-ad33-3b22-a1f1-eb499a0e8419},\n group_id = {9be6478b-54cd-3713-9237-f1e3cf6da833},\n last_modified = {2020-07-18T08:43:14.557Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Rebling2018a},\n private_publication = {false},\n abstract = {© 2018 Optical Society of America. Radio frequency (RF) catheter ablation is commonly used to eliminate dysfunctional cardiac tissue by heating via an alternating current. Clinical outcomes are highly dependent on careful anatomical guidance, electrophysiological mapping, and careful RF power titration during the procedure. Yet, current treatments rely mainly on the expertise of the surgeon to assess lesion formation, causing large variabilities in the success rate. We present an integrated catheter design suitable for simultaneous RF ablation and real-time optoacoustic monitoring of the forming lesion. The catheter design utilizes copper-coated multimode light guides capable of delivering both ablation current and near-infrared pulsed-laser illumination to the target tissue. The generated optoacoustic responses were used to visualize the ablation lesion formation in an ex-vivo bovine heart specimen in 3D. The presented catheter design enables the monitoring of ablation lesions with high spatiotemporal resolution while the overall therapy-monitoring approach remains compatible with commercially available catheter designs.},\n bibtype = {article},\n author = {Rebling, Johannes and Oyaga Landa, Francisco Javier and Deán-Ben, Xosé Luís and Douplik, Alexandre and Razansky, Daniel},\n doi = {10.1364/ol.43.001886},\n journal = {Optics Letters},\n number = {8}\n}
\n
\n\n\n
\n © 2018 Optical Society of America. Radio frequency (RF) catheter ablation is commonly used to eliminate dysfunctional cardiac tissue by heating via an alternating current. Clinical outcomes are highly dependent on careful anatomical guidance, electrophysiological mapping, and careful RF power titration during the procedure. Yet, current treatments rely mainly on the expertise of the surgeon to assess lesion formation, causing large variabilities in the success rate. We present an integrated catheter design suitable for simultaneous RF ablation and real-time optoacoustic monitoring of the forming lesion. The catheter design utilizes copper-coated multimode light guides capable of delivering both ablation current and near-infrared pulsed-laser illumination to the target tissue. The generated optoacoustic responses were used to visualize the ablation lesion formation in an ex-vivo bovine heart specimen in 3D. The presented catheter design enables the monitoring of ablation lesions with high spatiotemporal resolution while the overall therapy-monitoring approach remains compatible with commercially available catheter designs.\n
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\n
\n  \n 2017\n \n \n (1)\n \n \n
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\n \n \n
\n \n\n \n \n \n \n \n \n Optical imaging of post-embryonic zebrafish using multi orientation raster scan optoacoustic mesoscopy.\n \n \n \n \n\n\n \n Omar, M.; Rebling, J.; Wicker, K.; Schmitt-Manderbach, T.; Schwarz, M.; Gateau, J.; López-Schier, H.; Mappes, T.; and Ntziachristos, V.\n\n\n \n\n\n\n Light: Science and Applications, 6(1): e16186-e16186. 1 2017.\n \n\n\n\n
\n\n\n\n \n \n \"OpticalWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
\n 
@article{\n title = {Optical imaging of post-embryonic zebrafish using multi orientation raster scan optoacoustic mesoscopy},\n type = {article},\n year = {2017},\n keywords = {deconvolution,development,mesoscopy,multiview,optoacoustics,photoacoustics},\n pages = {e16186-e16186},\n volume = {6},\n websites = {http://www.nature.com/articles/lsa2016186},\n month = {1},\n day = {11},\n id = {16ecc034-a2f0-3fff-9656-556cefcfe4ee},\n created = {2020-07-11T11:23:46.025Z},\n file_attached = {false},\n profile_id = {324e2dd8-ad33-3b22-a1f1-eb499a0e8419},\n group_id = {9be6478b-54cd-3713-9237-f1e3cf6da833},\n last_modified = {2020-07-18T08:43:14.270Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Omar2017},\n private_publication = {false},\n abstract = {Whole-body optical imaging of post-embryonic stage model organisms is a challenging and long sought-after goal. It requires a combination of high-resolution performance and high-penetration depth. Optoacoustic (photoacoustic) mesoscopy holds great promise, as it penetrates deeper than optical and optoacoustic microscopy while providing high-spatial resolution. However, optoacoustic mesoscopic techniques only offer partial visibility of oriented structures, such as blood vessels, due to a limited angular detection aperture or the use of ultrasound frequencies that yield insufficient resolution. We introduce 360° multi orientation (multi-projection) raster scan optoacoustic mesoscopy (MORSOM) based on detecting an ultra-wide frequency bandwidth (up to 160 MHz) and weighted deconvolution to synthetically enlarge the angular aperture. We report unprecedented isotropic in-plane resolution at the 9-17 μm range and improved signal to noise ratio in phantoms and opaque 21-day-old Zebrafish. We find that MORSOM performance defines a new operational specification for optoacoustic mesoscopy of adult organisms, with possible applications in the developmental biology of adulthood and aging.},\n bibtype = {article},\n author = {Omar, Murad and Rebling, Johannes and Wicker, Kai and Schmitt-Manderbach, Tobias and Schwarz, Mathias and Gateau, Jérôme and López-Schier, Hérnan and Mappes, Timo and Ntziachristos, Vasilis},\n doi = {10.1038/lsa.2016.186},\n journal = {Light: Science and Applications},\n number = {1}\n}
\n
\n\n\n
\n Whole-body optical imaging of post-embryonic stage model organisms is a challenging and long sought-after goal. It requires a combination of high-resolution performance and high-penetration depth. Optoacoustic (photoacoustic) mesoscopy holds great promise, as it penetrates deeper than optical and optoacoustic microscopy while providing high-spatial resolution. However, optoacoustic mesoscopic techniques only offer partial visibility of oriented structures, such as blood vessels, due to a limited angular detection aperture or the use of ultrasound frequencies that yield insufficient resolution. We introduce 360° multi orientation (multi-projection) raster scan optoacoustic mesoscopy (MORSOM) based on detecting an ultra-wide frequency bandwidth (up to 160 MHz) and weighted deconvolution to synthetically enlarge the angular aperture. We report unprecedented isotropic in-plane resolution at the 9-17 μm range and improved signal to noise ratio in phantoms and opaque 21-day-old Zebrafish. We find that MORSOM performance defines a new operational specification for optoacoustic mesoscopy of adult organisms, with possible applications in the developmental biology of adulthood and aging.\n
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\n  \n 2013\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n \n Chirped-pulse and cavity-based fourier transform microwave spectroscopy of a chiral epoxy ester: Methyl glycidate.\n \n \n \n \n\n\n \n Thomas, J.; Yiu, J.; Rebling, J.; Jäger, W.; and Xu, Y.\n\n\n \n\n\n\n Journal of Physical Chemistry A, 117(50): 13249-13254. 12 2013.\n \n\n\n\n
\n\n\n\n \n \n \"Chirped-pulseWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n 
@article{\n title = {Chirped-pulse and cavity-based fourier transform microwave spectroscopy of a chiral epoxy ester: Methyl glycidate},\n type = {article},\n year = {2013},\n pages = {13249-13254},\n volume = {117},\n websites = {http://pubs.acs.org/doi/10.1021/jp402552t},\n month = {12},\n day = {19},\n id = {6bdbc21e-765d-35e0-bada-3df857515260},\n created = {2020-07-11T11:23:46.028Z},\n file_attached = {false},\n profile_id = {324e2dd8-ad33-3b22-a1f1-eb499a0e8419},\n group_id = {9be6478b-54cd-3713-9237-f1e3cf6da833},\n last_modified = {2020-07-18T08:43:14.381Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Thomas2013},\n private_publication = {false},\n abstract = {Rotational spectra of a chiral epoxy ester, methyl glycidate, were measured using a chirped-pulse and a cavity-based Fourier transform microwave spectrometer. The two lowest energy conformers where the epoxy oxygen and the ester oxygen atoms are in the syn and anti relative orientation with respect to each other were identified experimentally. Spectra of four 13C isotopologues of the lowest energy conformer of methyl glycidate were also measured and assigned. All of the observed rotational transitions are split into doublets due to the presence of the ester methyl internal rotor. The rotational constants and the internal rotation barrier height for the ester methyl group were determined for both conformers of methyl glycidate and for the four 13C isotopologues of the most stable conformer. A value for the interconversion barrier between the two most stable conformers was estimated. Furthermore, comparison to strawberry aldehyde, a larger derivative of methyl glycidate, shows how the syn-anti conformational equilibrium shifts as a result of the additional bulky substituents at the epoxy ring and at the ester oxygen atom. © 2013 American Chemical Society.},\n bibtype = {article},\n author = {Thomas, Javix and Yiu, Jensen and Rebling, Johannes and Jäger, Wolfgang and Xu, Yunjie},\n doi = {10.1021/jp402552t},\n journal = {Journal of Physical Chemistry A},\n number = {50}\n}
\n
\n\n\n
\n Rotational spectra of a chiral epoxy ester, methyl glycidate, were measured using a chirped-pulse and a cavity-based Fourier transform microwave spectrometer. The two lowest energy conformers where the epoxy oxygen and the ester oxygen atoms are in the syn and anti relative orientation with respect to each other were identified experimentally. Spectra of four 13C isotopologues of the lowest energy conformer of methyl glycidate were also measured and assigned. All of the observed rotational transitions are split into doublets due to the presence of the ester methyl internal rotor. The rotational constants and the internal rotation barrier height for the ester methyl group were determined for both conformers of methyl glycidate and for the four 13C isotopologues of the most stable conformer. A value for the interconversion barrier between the two most stable conformers was estimated. Furthermore, comparison to strawberry aldehyde, a larger derivative of methyl glycidate, shows how the syn-anti conformational equilibrium shifts as a result of the additional bulky substituents at the epoxy ring and at the ester oxygen atom. © 2013 American Chemical Society.\n
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\n  \n 2012\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n \n All-optical switching of a signal by a pair of interacting nematicons.\n \n \n \n \n\n\n \n Izdebskaya, Y., V.; Rebling, J.; Desyatnikov, A., S.; Assanto, G.; and Kivshar, Y., S.\n\n\n \n\n\n\n Optics Express, 20(22): 24701. 10 2012.\n \n\n\n\n
\n\n\n\n \n \n \"All-opticalWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{\n title = {All-optical switching of a signal by a pair of interacting nematicons},\n type = {article},\n year = {2012},\n pages = {24701},\n volume = {20},\n websites = {https://www.osapublishing.org/oe/abstract.cfm?uri=oe-20-22-24701},\n month = {10},\n day = {22},\n id = {e9802a12-378f-3b75-95a3-b926ad384f47},\n created = {2020-07-11T11:23:46.412Z},\n file_attached = {false},\n profile_id = {324e2dd8-ad33-3b22-a1f1-eb499a0e8419},\n group_id = {9be6478b-54cd-3713-9237-f1e3cf6da833},\n last_modified = {2020-07-18T08:43:14.386Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Izdebskaya2012},\n private_publication = {false},\n abstract = {We investigate a power tunable junction formed by two interacting spatial solitons self-trapped in nematic liquid crystals. By launching a counter-propagating copolarized probe we assess the guided-wave behavior induced by the solitons and demonstrate a novel all-optical switch. Varying soliton power the probe gets trapped into one or two or three guided-waves by the soliton-induced index perturbation, an effect supported by the nonlocal nonlinearity. © 2012 Optical Society of America.},\n bibtype = {article},\n author = {Izdebskaya, Ya. V. and Rebling, J. and Desyatnikov, A. S. and Assanto, G. and Kivshar, Yu. S.},\n doi = {10.1364/oe.20.024701},\n journal = {Optics Express},\n number = {22}\n}
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\n We investigate a power tunable junction formed by two interacting spatial solitons self-trapped in nematic liquid crystals. By launching a counter-propagating copolarized probe we assess the guided-wave behavior induced by the solitons and demonstrate a novel all-optical switch. Varying soliton power the probe gets trapped into one or two or three guided-waves by the soliton-induced index perturbation, an effect supported by the nonlocal nonlinearity. © 2012 Optical Society of America.\n
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