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\n  \n 2021\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n \n 2021 Dangerous Goods Regulations Manual.\n \n \n \n \n\n\n \n \n\n\n \n\n\n\n 62 edition, 2021.\n \n\n\n\n
\n\n\n\n \n \n \"2021Website\n  \n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n 
@book{\n title = {2021 Dangerous Goods Regulations Manual},\n type = {book},\n year = {2021},\n websites = {https://store.iata.org/IEC_ProductDetails?id=9065-62&_ga=2.268599413.528324038.1605693602-1564562712.1605693599&_gac=1.247354870.1605693663.Cj0KCQiAqdP9BRDVARIsAGSZ8AkFYEsIDfTIN_bDCgdT2J0pYCFGjOoFSWSyLSJ1oK_hpk0qrW0U6LQaAh8qEALw_wcB},\n edition = {62},\n id = {c47ecca2-2ff0-3e7e-b595-8a7296334625},\n created = {2020-11-18T10:08:11.965Z},\n accessed = {2020-11-18},\n file_attached = {false},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2021-01-16T01:01:36.683Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n private_publication = {false},\n bibtype = {book},\n author = {}\n}
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\n  \n 2020\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n \n Technical and Anatomical Considerations for Reproducible Inactivation of Large Animal Carcasses by Steam Sterilization.\n \n \n \n \n\n\n \n Schinköthe, J.; Bartram-Sitzius, B.; Teifke, J., P.; Pfitzner, U.; and Reiche, S.\n\n\n \n\n\n\n Applied Biosafety. 2020.\n \n\n\n\n
\n\n\n\n \n \n \"TechnicalPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
\n 
@article{\n title = {Technical and Anatomical Considerations for Reproducible Inactivation of Large Animal Carcasses by Steam Sterilization},\n type = {article},\n year = {2020},\n keywords = {biological indicator,calf,carcass inactivation,large animal,pig,steam sterilization},\n publisher = {SAGE Publications Inc.},\n id = {5834837d-deb7-33ca-9113-5fdeb60d7452},\n created = {2020-11-16T02:35:00.516Z},\n accessed = {2020-11-16},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2021-01-15T23:29:14.894Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n private_publication = {false},\n abstract = {Introduction: The complete inactivation of infectious tissues of large animal carcasses is one of the most challenging tasks in high-containment facilities. Steam sterilization is a method frequently in use to achieve biological inactivation of liquid and solid waste. Objective: This study aims to highlight parameters most effective in creating reproducible cycles for steam sterilization of pig and calf carcasses. Methods: Two pigs or 1 calf were sterilized by running a liquid cycle (n = 3) at 121°C for at least 120 minutes in a pass-through autoclave. To assess the physical and biological parameters, temperature data loggers and biological indicators (BIs) with spores of Geobacillus stearothermophilus (ATCC 7953) were placed at defined positions within animal carcasses. After completion of each cycle, data loggers were analyzed and BIs were incubated for 7 days at 60°C. Results: Initial testing with an undissected pig carcass resulted in suboptimal temperatures at the tissue level with growth on 1 BI. After modifications of the used stainless-steel boxes and by placing the reference probe of the autoclave in the animal carcass, reproducible cycles could be created. A complete inactivation of BIs and a temperature profile of >121°C for at least 20 minutes could be achieved in almost all probed tissues. Conclusion: Only minor modifications in carcass preparation and the used sterilization equipment resulted in effective and reproducible cycles to inactivate large animal carcasses by using a steam autoclave.},\n bibtype = {article},\n author = {Schinköthe, Jan and Bartram-Sitzius, Benjamin and Teifke, Jens Peter and Pfitzner, Ute and Reiche, Sven},\n doi = {10.1177/1535676020919637},\n journal = {Applied Biosafety}\n}
\n
\n\n\n
\n Introduction: The complete inactivation of infectious tissues of large animal carcasses is one of the most challenging tasks in high-containment facilities. Steam sterilization is a method frequently in use to achieve biological inactivation of liquid and solid waste. Objective: This study aims to highlight parameters most effective in creating reproducible cycles for steam sterilization of pig and calf carcasses. Methods: Two pigs or 1 calf were sterilized by running a liquid cycle (n = 3) at 121°C for at least 120 minutes in a pass-through autoclave. To assess the physical and biological parameters, temperature data loggers and biological indicators (BIs) with spores of Geobacillus stearothermophilus (ATCC 7953) were placed at defined positions within animal carcasses. After completion of each cycle, data loggers were analyzed and BIs were incubated for 7 days at 60°C. Results: Initial testing with an undissected pig carcass resulted in suboptimal temperatures at the tissue level with growth on 1 BI. After modifications of the used stainless-steel boxes and by placing the reference probe of the autoclave in the animal carcass, reproducible cycles could be created. A complete inactivation of BIs and a temperature profile of >121°C for at least 20 minutes could be achieved in almost all probed tissues. Conclusion: Only minor modifications in carcass preparation and the used sterilization equipment resulted in effective and reproducible cycles to inactivate large animal carcasses by using a steam autoclave.\n
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\n  \n 2016\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n \n GOHLD GUIDELINES FOR Livestock Biosafety Manual Development.\n \n \n \n \n\n\n \n Group of High-Containment Laboratory Directors\n\n\n \n\n\n\n Technical Report 2016.\n \n\n\n\n
\n\n\n\n \n \n \"GOHLDWebsite\n  \n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n 
@techreport{\n title = {GOHLD GUIDELINES FOR Livestock Biosafety Manual Development},\n type = {techreport},\n year = {2016},\n pages = {140},\n websites = {http://www.ivbw.camp9.org/resources/Documents/GOHLD Guidance 2016/GOHLD Final Admin Update 042516.pdf},\n id = {23dcd5c6-7f9b-331e-84a9-96b5ae8a7da1},\n created = {2018-05-01T03:35:34.570Z},\n file_attached = {false},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2018-05-18T09:46:30.741Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {GroupofHigh-ContainmentLaboratoryDirectors2016},\n private_publication = {false},\n bibtype = {techreport},\n author = {Group of High-Containment Laboratory Directors, undefined}\n}
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\n  \n 2014\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n \n The Network of Animal Disease Infectiology and Research Facilities: Final Report.\n \n \n \n \n\n\n \n NADIR\n\n\n \n\n\n\n Technical Report 2014.\n \n\n\n\n
\n\n\n\n \n \n \"ThePaper\n  \n \n \n \"TheWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n 
@techreport{\n title = {The Network of Animal Disease Infectiology and Research Facilities: Final Report},\n type = {techreport},\n year = {2014},\n websites = {https://zenodo.org/record/438722#.WNr7VTsrJaQ},\n id = {99a62bf6-e309-3eb0-afe4-33227549ecdc},\n created = {2018-05-01T00:29:33.679Z},\n accessed = {2017-03-29},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2018-05-01T00:29:33.768Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {NADIR2014a},\n private_publication = {false},\n bibtype = {techreport},\n author = {NADIR, undefined},\n doi = {10.5281/ZENODO.438722}\n}
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\n  \n 2013\n \n \n (8)\n \n \n
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\n \n\n \n \n \n \n \n \n Best Practice On The Selection, Validation And Use Of Disinfectants In High Containment Animal Facilities.\n \n \n \n \n\n\n \n Abad, F., X.; and Solanes Foz, D.\n\n\n \n\n\n\n Technical Report 11 2013.\n \n\n\n\n
\n\n\n\n \n \n \"BestPaper\n  \n \n \n \"BestWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n\n\n\n
\n 
@techreport{\n title = {Best Practice On The Selection, Validation And Use Of Disinfectants In High Containment Animal Facilities},\n type = {techreport},\n year = {2013},\n keywords = {high containment,validation,veterinary disinfectants},\n websites = {https://doi.org/10.5281/zenodo.822076#.WWQ5XKbrL1E.mendeley},\n month = {11},\n day = {1},\n id = {df349cb1-79eb-35ee-8182-eae4636e8fd7},\n created = {2017-07-11T02:38:11.576Z},\n accessed = {2017-07-11},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2018-05-18T09:46:30.653Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Abad2013a},\n private_publication = {false},\n abstract = {This Best Practice Guidance covers the requirements for the selection and validation of disinfectants for use in containment level 3 (CL3) farm animal facilities It is important any disinfectant used in CL3 animal facilities must be selected and validated as fit for purpose with regard to both the target organism and also the situation of use.},\n bibtype = {techreport},\n author = {Abad, Francesc Xavier and Solanes Foz, David},\n doi = {10.5281/ZENODO.822076}\n}
\n
\n\n\n
\n This Best Practice Guidance covers the requirements for the selection and validation of disinfectants for use in containment level 3 (CL3) farm animal facilities It is important any disinfectant used in CL3 animal facilities must be selected and validated as fit for purpose with regard to both the target organism and also the situation of use.\n
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\n \n\n \n \n \n \n \n \n Best Practice for House Keeping in Animal High Containment Facilities.\n \n \n \n \n\n\n \n Simmons, H.\n\n\n \n\n\n\n Technical Report 8 2013.\n \n\n\n\n
\n\n\n\n \n \n \"BestPaper\n  \n \n \n \"BestWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n\n\n\n
\n 
@techreport{\n title = {Best Practice for House Keeping in Animal High Containment Facilities},\n type = {techreport},\n year = {2013},\n keywords = {animal facilities,biosafety,hygiene},\n websites = {https://zenodo.org/record/1156398},\n month = {8},\n day = {3},\n id = {5d52fb0b-a9c4-321e-b7a7-8514a5209d47},\n created = {2018-05-01T01:46:17.497Z},\n accessed = {2018-05-01},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2018-05-01T11:46:35.235Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n private_publication = {false},\n bibtype = {techreport},\n author = {Simmons, Hugh},\n doi = {10.5281/ZENODO.1156398}\n}
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\n \n\n \n \n \n \n \n \n Animal rooms: fumigation and sealability requirements.\n \n \n \n \n\n\n \n Simmons, H.\n\n\n \n\n\n\n Technical Report 11 2013.\n \n\n\n\n
\n\n\n\n \n \n \"AnimalPaper\n  \n \n \n \"AnimalWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n 
@techreport{\n title = {Animal rooms: fumigation and sealability requirements},\n type = {techreport},\n year = {2013},\n websites = {https://zenodo.org/record/822082},\n month = {11},\n day = {17},\n id = {9305fa18-cbbd-3d41-a65d-372b0297d739},\n created = {2018-05-01T02:48:03.824Z},\n accessed = {2018-05-01},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2018-05-01T03:01:25.053Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Simmons2013},\n private_publication = {false},\n bibtype = {techreport},\n author = {Simmons, Hugh},\n doi = {10.5281/ZENODO.822082}\n}
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\n \n\n \n \n \n \n \n \n Best Practice for Fumigation using Formaldehyde (Microbiological Safety Cabinets, Isolators and Rooms).\n \n \n \n \n\n\n \n Simmons, H.\n\n\n \n\n\n\n Technical Report 6 2013.\n \n\n\n\n
\n\n\n\n \n \n \"BestPaper\n  \n \n \n \"BestWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n\n\n\n
\n 
@techreport{\n title = {Best Practice for Fumigation using Formaldehyde (Microbiological Safety Cabinets, Isolators and Rooms)},\n type = {techreport},\n year = {2013},\n keywords = {Gaseous decontamination,formaldehyde},\n websites = {https://zenodo.org/record/1156396},\n month = {6},\n day = {30},\n id = {07f6479f-94b9-31be-9872-9d0e80030ba7},\n created = {2018-05-01T02:48:03.827Z},\n accessed = {2018-05-01},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2018-05-01T11:46:35.741Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n private_publication = {false},\n bibtype = {techreport},\n author = {Simmons, Hugh},\n doi = {10.5281/ZENODO.1156396}\n}
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\n \n\n \n \n \n \n \n \n High Containment Facilities Building Officer – Guidance Notes.\n \n \n \n \n\n\n \n Simmons, H.\n\n\n \n\n\n\n Technical Report 11 2013.\n \n\n\n\n
\n\n\n\n \n \n \"HighPaper\n  \n \n \n \"HighWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n\n\n\n
\n 
@techreport{\n title = {High Containment Facilities Building Officer – Guidance Notes},\n type = {techreport},\n year = {2013},\n keywords = {biosafety,building officer,high containment},\n websites = {https://zenodo.org/record/822129},\n month = {11},\n day = {1},\n id = {f40436c6-ef93-31a5-9f72-1f75ecaedf64},\n created = {2018-05-01T02:48:03.858Z},\n accessed = {2018-05-01},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2018-05-18T09:46:30.739Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Simmons2013b},\n private_publication = {false},\n bibtype = {techreport},\n author = {Simmons, Hugh},\n doi = {10.5281/ZENODO.822129}\n}
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\n \n\n \n \n \n \n \n \n Emergency Procedures and Contingency Planning in Containment Facilities.\n \n \n \n \n\n\n \n Simmons, H.\n\n\n \n\n\n\n Technical Report 10 2013.\n \n\n\n\n
\n\n\n\n \n \n \"EmergencyPaper\n  \n \n \n \"EmergencyWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n\n\n\n
\n 
@techreport{\n title = {Emergency Procedures and Contingency Planning in Containment Facilities},\n type = {techreport},\n year = {2013},\n keywords = {biosafety facility,contingency planning},\n websites = {https://zenodo.org/record/1156394},\n month = {10},\n day = {14},\n id = {a2b156cb-e5c3-3664-b192-1c1324460616},\n created = {2018-05-01T02:48:03.866Z},\n accessed = {2018-05-01},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2018-05-18T09:46:30.661Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n citation_key = {Simmons2013a},\n private_publication = {false},\n bibtype = {techreport},\n author = {Simmons, Hugh},\n doi = {10.5281/ZENODO.1156394}\n}
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\n \n\n \n \n \n \n \n \n Training and Competence for Working in Containment Level 3 Animal Facilities.\n \n \n \n \n\n\n \n Simmons, H.\n\n\n \n\n\n\n Technical Report 10 2013.\n \n\n\n\n
\n\n\n\n \n \n \"TrainingPaper\n  \n \n \n \"TrainingWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n 
@techreport{\n title = {Training and Competence for Working in Containment Level 3 Animal Facilities},\n type = {techreport},\n year = {2013},\n websites = {https://zenodo.org/record/822072},\n month = {10},\n day = {23},\n id = {ce1e4f8a-326a-3847-9d84-eb86277b92cb},\n created = {2018-05-01T02:48:03.868Z},\n accessed = {2018-05-01},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2018-05-01T03:04:44.459Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n private_publication = {false},\n bibtype = {techreport},\n author = {Simmons, Hugh},\n doi = {10.5281/ZENODO.822072}\n}
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\n \n\n \n \n \n \n \n \n Biosafety considerations for in vivo work with risk group 3 pathogens in large animals and wildlife in North America.\n \n \n \n \n\n\n \n Olsen, S., C.\n\n\n \n\n\n\n 2013.\n \n\n\n\n
\n\n\n\n \n \n \"BiosafetyWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
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@misc{\n title = {Biosafety considerations for in vivo work with risk group 3 pathogens in large animals and wildlife in North America.},\n type = {misc},\n year = {2013},\n source = {Animal health research reviews / Conference of Research Workers in Animal Diseases},\n keywords = {Animal Diseases / epidemiology,Animal Diseases / prevention & control*,Animals,MEDLINE,NCBI,NIH,NLM,National Center for Biotechnology Information,National Institutes of Health,National Library of Medicine,North America,PubMed Abstract,Review,S C Olsen,United States / epidemiology,Wild / microbiology,Zoonoses / epidemiology,Zoonoses / prevention & control*,doi:10.1017/S1466252312000217,pmid:23286223},\n pages = {2-10},\n volume = {14},\n issue = {1},\n websites = {https://pubmed.ncbi.nlm.nih.gov/23286223/},\n publisher = {Anim Health Res Rev},\n id = {1f5b0344-dbf9-3902-8535-e2637a102b20},\n created = {2020-09-24T09:43:28.188Z},\n accessed = {2020-09-24},\n file_attached = {false},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2021-01-15T23:29:10.470Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n private_publication = {false},\n abstract = {Regulations in the United States require animal biosafety level 3 (ABSL-3) or biosafety level 3 agriculture (BSL-3-Ag) containment for many endemic zoonotic pathogens and etiologic agents of foreign animal diseases. In an effort to protect public health, billions of dollars were invested in regulatory programs over many years to reduce the prevalence of zoonotic pathogens such as Brucella and Mycobacterium bovis in domestic livestock. In addition to research needs in domestic livestock hosts, the establishment of brucellosis and tuberculosis in wildlife in the United States has created a need for research studies addressing these zoonotic diseases. As guidelines in the Biosafety in Microbiological and Biomedical Laboratories (BMBL, 2009) for BSL-3 and BSL-3-Ag facilities are primarily directed toward laboratory or vivarium facilities, additional issues should be considered in designing large animal containment facilities for domestic livestock and/or wildlife. Flight distance, herd orientation, social needs, aggressiveness, and predictability are all factors we considered on a species by species basis for designing our containment facilities and for work practices with large ruminants. Although safety risk cannot be completely eliminated when working with large animals, studies in natural hosts are critical for advancing vaccine and diagnostic development, and providing basic knowledge of disease pathogenesis in natural hosts. Data gathered in these types of studies are vital for state and national regulatory personnel in their efforts to design strategies to control or eradicate diseases such as brucellosis and tuberculosis in their natural hosts, whether it is domestic livestock or wildlife. It is likely that failure to address the prevalence of disease in wildlife reservoirs will lead to re-emergence in domestic livestock. The overall benefit of these studies is to protect public health, provide economic benefits to producers, and protect the economic investment made in regulatory programs.},\n bibtype = {misc},\n author = {Olsen, S. C.},\n doi = {10.1017/S1466252312000217}\n}
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\n Regulations in the United States require animal biosafety level 3 (ABSL-3) or biosafety level 3 agriculture (BSL-3-Ag) containment for many endemic zoonotic pathogens and etiologic agents of foreign animal diseases. In an effort to protect public health, billions of dollars were invested in regulatory programs over many years to reduce the prevalence of zoonotic pathogens such as Brucella and Mycobacterium bovis in domestic livestock. In addition to research needs in domestic livestock hosts, the establishment of brucellosis and tuberculosis in wildlife in the United States has created a need for research studies addressing these zoonotic diseases. As guidelines in the Biosafety in Microbiological and Biomedical Laboratories (BMBL, 2009) for BSL-3 and BSL-3-Ag facilities are primarily directed toward laboratory or vivarium facilities, additional issues should be considered in designing large animal containment facilities for domestic livestock and/or wildlife. Flight distance, herd orientation, social needs, aggressiveness, and predictability are all factors we considered on a species by species basis for designing our containment facilities and for work practices with large ruminants. Although safety risk cannot be completely eliminated when working with large animals, studies in natural hosts are critical for advancing vaccine and diagnostic development, and providing basic knowledge of disease pathogenesis in natural hosts. Data gathered in these types of studies are vital for state and national regulatory personnel in their efforts to design strategies to control or eradicate diseases such as brucellosis and tuberculosis in their natural hosts, whether it is domestic livestock or wildlife. It is likely that failure to address the prevalence of disease in wildlife reservoirs will lead to re-emergence in domestic livestock. The overall benefit of these studies is to protect public health, provide economic benefits to producers, and protect the economic investment made in regulatory programs.\n
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\n  \n 2009\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n \n Infection control in the management of highly pathogenic infectious diseases: consensus of the European Network of Infectious Disease.\n \n \n \n \n\n\n \n Brouqui, P.; Puro, V.; Fusco, F., M.; Bannister, B.; Schilling, S.; Follin, P.; Gottschalk, R.; Hemmer, R.; Maltezou, H., C.; Ott, K.; Peleman, R.; Perronne, C.; Sheehan, G.; Siikamäki, H.; Skinhoj, P.; and Ippolito, G.\n\n\n \n\n\n\n 5 2009.\n \n\n\n\n
\n\n\n\n \n \n \"InfectionPaper\n  \n \n \n \"InfectionWebsite\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@misc{\n title = {Infection control in the management of highly pathogenic infectious diseases: consensus of the European Network of Infectious Disease},\n type = {misc},\n year = {2009},\n source = {The Lancet Infectious Diseases},\n pages = {301-311},\n volume = {9},\n issue = {5},\n websites = {/pmc/articles/PMC7106353/?report=abstract,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106353/},\n month = {5},\n publisher = {Elsevier},\n id = {aae93928-4535-396b-a8ba-b25d10b4728c},\n created = {2020-09-06T11:31:46.735Z},\n accessed = {2020-09-06},\n file_attached = {true},\n profile_id = {f7328406-3e7e-3e37-9ea0-01d7cb781b09},\n group_id = {3455ce01-3ebd-33b1-bddf-c7304973b8e6},\n last_modified = {2021-01-15T23:29:07.577Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n private_publication = {false},\n abstract = {The European Network for Infectious Diseases (EUNID) is a network of clinicians, public health epidemiologists, microbiologists, infection control, and critical-care doctors from the European member states, who are experienced in the management of patients with highly infectious diseases. We aim to develop a consensus recommendation for infection control during clinical management and invasive procedures in such patients. After an extensive literature review, draft recommendations were amended jointly by 27 partners from 15 European countries. Recommendations include repetitive training of staff to ascertain infection control, systematic use of cough and respiratory etiquette at admission to the emergency department, fluid sampling in the isolation room, and analyses in biosafety level 3/4 laboratories, and preference for point-of-care bedside laboratory tests. Children should be cared for by paediatricians and intensive-care patients should be cared for by critical-care doctors in high-level isolation units (HLIU). Invasive procedures should be avoided if unnecessary or done in the HLIU, as should chest radiography, ultrasonography, and renal dialysis. Procedures that require transport of patients out of the HLIU should be done during designated sessions or hours in secure transport. Picture archiving and communication systems should be used. Post-mortem examination should be avoided; biopsy or blood collection is preferred. © 2009 Elsevier Ltd. All rights reserved.},\n bibtype = {misc},\n author = {Brouqui, Philippe and Puro, Vincenzo and Fusco, Francesco M. and Bannister, Barbara and Schilling, Stephan and Follin, Per and Gottschalk, René and Hemmer, Robert and Maltezou, Helena C. and Ott, Kristi and Peleman, Renaat and Perronne, Christian and Sheehan, Gerard and Siikamäki, Heli and Skinhoj, Peter and Ippolito, Giuseppe},\n doi = {10.1016/S1473-3099(09)70070-2}\n}
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\n The European Network for Infectious Diseases (EUNID) is a network of clinicians, public health epidemiologists, microbiologists, infection control, and critical-care doctors from the European member states, who are experienced in the management of patients with highly infectious diseases. We aim to develop a consensus recommendation for infection control during clinical management and invasive procedures in such patients. After an extensive literature review, draft recommendations were amended jointly by 27 partners from 15 European countries. Recommendations include repetitive training of staff to ascertain infection control, systematic use of cough and respiratory etiquette at admission to the emergency department, fluid sampling in the isolation room, and analyses in biosafety level 3/4 laboratories, and preference for point-of-care bedside laboratory tests. Children should be cared for by paediatricians and intensive-care patients should be cared for by critical-care doctors in high-level isolation units (HLIU). Invasive procedures should be avoided if unnecessary or done in the HLIU, as should chest radiography, ultrasonography, and renal dialysis. Procedures that require transport of patients out of the HLIU should be done during designated sessions or hours in secure transport. Picture archiving and communication systems should be used. Post-mortem examination should be avoided; biopsy or blood collection is preferred. © 2009 Elsevier Ltd. All rights reserved.\n
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