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\n \n \n Fix it now\n

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\n  \n 2021\n \n \n (3)\n \n \n
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\n \n\n \n \n \n \n \n Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion.\n \n \n \n\n\n \n Leatherdale, A.; Parker, D.; Tasneem, S.; Wang, Y.; Bihan, D.; Bonna, A.; Hamaia, S. W; Gross, P. L; Ni, H.; Doble, B. W; and others\n\n\n \n\n\n\n Journal of Thrombosis and Haemostasis, 19(2): 547. 2021.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{leatherdale2021multimerin,\n  title={Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion},\n  author={Leatherdale, Alexander and Parker, D’Andra and Tasneem, Subia and Wang, Yiming and Bihan, Dominique and Bonna, Arkadiusz and Hamaia, Samir W and Gross, Peter L and Ni, Heyu and Doble, Bradley W and others},\n  journal={Journal of Thrombosis and Haemostasis},\n  volume={19},\n  number={2},\n  pages={547},\n  year={2021},\n  publisher={Wiley-Blackwell}\n}\n\n
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\n \n\n \n \n \n \n \n TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state.\n \n \n \n\n\n \n Doumpas, N.; Söderholm, S.; Narula, S.; Moreira, S.; Doble, B. W; Cantù, C.; and Basler, K.\n\n\n \n\n\n\n Cell reports, 36(11): 109705. 2021.\n \n\n\n\n
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@article{doumpas2021tcf,\n  title={TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state},\n  author={Doumpas, Nikolaos and S{\\"o}derholm, Simon and Narula, Smarth and Moreira, Steven and Doble, Bradley W and Cant{\\`u}, Claudio and Basler, Konrad},\n  journal={Cell reports},\n  volume={36},\n  number={11},\n  pages={109705},\n  year={2021},\n  publisher={Cell Press}\n}\n\n
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\n \n\n \n \n \n \n \n Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis.\n \n \n \n\n\n \n Chan, D. C.; Xu, J.; Vujovic, A.; Wong, N.; Gordon, V.; de Rooij, L. P.; Moreira, S.; Joyce, C. E; La Rose, J.; Sandı́, Marı́a-José; and others\n\n\n \n\n\n\n Blood advances, 5(16): 3120–3133. 2021.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{chan2021arhgef2,\n  title={Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis},\n  author={Chan, Derek CH and Xu, Joshua and Vujovic, Ana and Wong, Nicholas and Gordon, Victor and de Rooij, Laura PMH and Moreira, Steven and Joyce, Cailin E and La Rose, Jose and Sand{\\'\\i}, Mar{\\'\\i}a-Jos{\\'e} and others},\n  journal={Blood advances},\n  volume={5},\n  number={16},\n  pages={3120--3133},\n  year={2021},\n  publisher={American Society of Hematology Washington, DC}\n}\n
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\n  \n 2020\n \n \n (3)\n \n \n
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\n \n\n \n \n \n \n \n A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells.\n \n \n \n\n\n \n Manoranjan, B.; Chokshi, C.; Venugopal, C.; Subapanditha, M.; Savage, N.; Tatari, N.; Provias, J. P; Murty, N. K; Moffat, J.; Doble, B. W; and others\n\n\n \n\n\n\n Oncogene, 39(7): 1590–1599. 2020.\n \n\n\n\n
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@article{manoranjan2020cd133,\n  title={A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells},\n  author={Manoranjan, Branavan and Chokshi, Chirayu and Venugopal, Chitra and Subapanditha, Minomi and Savage, Neil and Tatari, Nazanin and Provias, John P and Murty, Naresh K and Moffat, Jason and Doble, Bradley W and others},\n  journal={Oncogene},\n  volume={39},\n  number={7},\n  pages={1590--1599},\n  year={2020},\n  publisher={Nature Publishing Group}\n}\n\n
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\n \n\n \n \n \n \n \n $β$-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus.\n \n \n \n\n\n \n Zhang, M.; Lai, Y.; Krupalnik, V.; Guo, P.; Guo, X.; Zhou, J.; Xu, Y.; Yu, Z.; Liu, L.; Jiang, A.; and others\n\n\n \n\n\n\n Science advances, 6(29): eaba1593. 2020.\n \n\n\n\n
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@article{zhang2020beta,\n  title={$\\beta$-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus},\n  author={Zhang, Meng and Lai, Yiwei and Krupalnik, Vladislav and Guo, Pengcheng and Guo, Xiangpeng and Zhou, Jianguo and Xu, Yan and Yu, Zhijun and Liu, Longqi and Jiang, Ao and others},\n  journal={Science advances},\n  volume={6},\n  number={29},\n  pages={eaba1593},\n  year={2020},\n  publisher={American Association for the Advancement of Science}\n}\n\n
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\n \n\n \n \n \n \n \n Wnt activation as a therapeutic strategy in medulloblastoma.\n \n \n \n\n\n \n Manoranjan, B.; Venugopal, C.; Bakhshinyan, D.; Adile, A. A; Richards, L.; Kameda-Smith, M. M; Whitley, O.; Dvorkin-Gheva, A.; Subapanditha, M.; Savage, N.; and others\n\n\n \n\n\n\n Nature communications, 11(1): 1–12. 2020.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{manoranjan2020wnt,\n  title={Wnt activation as a therapeutic strategy in medulloblastoma},\n  author={Manoranjan, Branavan and Venugopal, Chitra and Bakhshinyan, David and Adile, Ashley A and Richards, Laura and Kameda-Smith, Michelle M and Whitley, Owen and Dvorkin-Gheva, Anna and Subapanditha, Minomi and Savage, Neil and others},\n  journal={Nature communications},\n  volume={11},\n  number={1},\n  pages={1--12},\n  year={2020},\n  publisher={Nature Publishing Group}\n}\n\n
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\n  \n 2019\n \n \n (5)\n \n \n
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\n \n\n \n \n \n \n \n Endogenous BioID elucidates TCF7L1 interactome modulation upon GSK-3 inhibition in mouse ESCs.\n \n \n \n\n\n \n Moreira, S.; Seo, C.; Gordon, V.; Xing, S.; Wu, R.; Polena, E.; Fung, V.; Ng, D.; Wong, C. J; Larsen, B.; and others\n\n\n \n\n\n\n Available at SSRN 3348349. 2019.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{moreira2019endogenous,\n  title={Endogenous BioID elucidates TCF7L1 interactome modulation upon GSK-3 inhibition in mouse ESCs},\n  author={Moreira, Steven and Seo, Caleb and Gordon, Victor and Xing, Sansi and Wu, Ruilin and Polena, Enio and Fung, Vincent and Ng, Deborah and Wong, Cassandra J and Larsen, Brett and others},\n  journal={Available at SSRN 3348349},\n  year={2019}\n}\n\n
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\n \n\n \n \n \n \n \n BMI1 is a therapeutic target in recurrent medulloblastoma.\n \n \n \n\n\n \n \n\n\n \n\n\n\n Oncogene, 38(10): 1702–1716. 2019.\n \n\n\n\n
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@article{bakhshinyan2019bmi1,\n  title={BMI1 is a therapeutic target in recurrent medulloblastoma.},\n  journal={Oncogene},\n  volume={38},\n  number={10},\n  pages={1702--1716},\n  year={2019}\n}\n\n
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\n \n\n \n \n \n \n \n Regulation of thymocyte $β$-selection, development and positive selection by glycogen synthase kinase-3.\n \n \n \n\n\n \n Parsons, M. J; Patel, S.; Doble, B. W; Ohashi, P. S; and Woodgett, J. R\n\n\n \n\n\n\n bioRxiv,712521. 2019.\n \n\n\n\n
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@article{parsons2019regulation,\n  title={Regulation of thymocyte $\\beta$-selection, development and positive selection by glycogen synthase kinase-3},\n  author={Parsons, Michael J and Patel, Satish and Doble, Bradley W and Ohashi, Pamela S and Woodgett, James R},\n  journal={bioRxiv},\n  pages={712521},\n  year={2019},\n  publisher={Cold Spring Harbor Laboratory}\n}\n\n
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\n \n\n \n \n \n \n \n OTUD7A regulates neurodevelopmental phenotypes in the 15q13. 3 microdeletion syndrome.\n \n \n \n\n\n \n Mohammed, U; Unda, B.; Kwan, V; Holzapfel, N.; White, S.; Chalil, L; Woodbury-Smith, M; Ho, K.; Harward, E; Murtaza, N; and others\n\n\n \n\n\n\n In EUROPEAN JOURNAL OF HUMAN GENETICS, volume 27, pages 840–841, 2019. NATURE PUBLISHING GROUP MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND\n \n\n\n\n
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@inproceedings{mohammed2019otud7a,\n  title={OTUD7A regulates neurodevelopmental phenotypes in the 15q13. 3 microdeletion syndrome},\n  author={Mohammed, U and Unda, BK and Kwan, V and Holzapfel, NT and White, SH and Chalil, L and Woodbury-Smith, M and Ho, KH and Harward, E and Murtaza, N and others},\n  booktitle={EUROPEAN JOURNAL OF HUMAN GENETICS},\n  volume={27},\n  pages={840--841},\n  year={2019},\n  organization={NATURE PUBLISHING GROUP MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND}\n}\n\n
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\n \n\n \n \n \n \n \n Lfc/Arhgef2 regulates mitotic spindle orientation in hematopoietic stem and progenitor cells and is essential for productive hematopoiesis.\n \n \n \n\n\n \n Chan, D. C.; Vujovic, A.; Xu, J.; Gordon, V.; Wong, N.; de Rooij, L. P.; Joyce, C. E; La Rose, J.; Sandi, M.; Doble, B. W; and others\n\n\n \n\n\n\n bioRxiv,855577. 2019.\n \n\n\n\n
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@article{chan2019lfc,\n  title={Lfc/Arhgef2 regulates mitotic spindle orientation in hematopoietic stem and progenitor cells and is essential for productive hematopoiesis},\n  author={Chan, Derek CH and Vujovic, Ana and Xu, Joshua and Gordon, Victor and Wong, Nicholas and de Rooij, Laura PMH and Joyce, Cailin E and La Rose, Jose and Sandi, Maria-Jose and Doble, Bradley W and others},\n  journal={bioRxiv},\n  pages={855577},\n  year={2019},\n  publisher={Cold Spring Harbor Laboratory}\n}\n\n
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\n  \n 2018\n \n \n (3)\n \n \n
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\n \n\n \n \n \n \n \n Canonical Wnt activation as a therapeutic strategy in pediatric medulloblastoma.\n \n \n \n\n\n \n Singh, S. K.; Manoranjan, B.; Dvorkin-Gheva, A.; Venugopal, C.; Moreira, S.; Kameda-Smith, M.; Subapanditha, M.; Adile, A.; Bakhshinyan, D.; Savage, N.; and others\n\n\n \n\n\n\n 2018.\n \n\n\n\n
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@misc{singh2018canonical,\n  title={Canonical Wnt activation as a therapeutic strategy in pediatric medulloblastoma},\n  author={Singh, Sheila Kumari and Manoranjan, Branavan and Dvorkin-Gheva, Anna and Venugopal, Chitra and Moreira, Steven and Kameda-Smith, Michelle and Subapanditha, Minomi and Adile, Ashley and Bakhshinyan, David and Savage, Neil and others},\n  year={2018},\n  publisher={American Association for Cancer Research}\n}\n\n
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\n \n\n \n \n \n \n \n TCF7L1 and TCF7 differentially regulate specific mouse ES cell genes in response to GSK-3 inhibition.\n \n \n \n\n\n \n Moreira, S.; Seo, C.; Polena, E.; Mahendram, S.; Mercier, E.; Blais, A.; and Doble, B. W\n\n\n \n\n\n\n bioRxiv,473801. 2018.\n \n\n\n\n
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@article{moreira2018tcf7l1,\n  title={TCF7L1 and TCF7 differentially regulate specific mouse ES cell genes in response to GSK-3 inhibition},\n  author={Moreira, Steven and Seo, Caleb and Polena, Enio and Mahendram, Sujeivan and Mercier, Eloi and Blais, Alexandre and Doble, Bradley W},\n  journal={bioRxiv},\n  pages={473801},\n  year={2018},\n  publisher={Cold Spring Harbor Laboratory}\n}\n\n
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\n \n\n \n \n \n \n \n OTUD7A regulates neurodevelopmental phenotypes in the 15q13. 3 microdeletion syndrome.\n \n \n \n\n\n \n Uddin, M.; Unda, B. K; Kwan, V.; Holzapfel, N. T; White, S. H; Chalil, L.; Woodbury-Smith, M.; Ho, K. S; Harward, E.; Murtaza, N.; and others\n\n\n \n\n\n\n The American Journal of Human Genetics, 102(2): 278–295. 2018.\n \n\n\n\n
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@article{uddin2018otud7a,\n  title={OTUD7A regulates neurodevelopmental phenotypes in the 15q13. 3 microdeletion syndrome},\n  author={Uddin, Mohammed and Unda, Brianna K and Kwan, Vickie and Holzapfel, Nicholas T and White, Sean H and Chalil, Leon and Woodbury-Smith, Marc and Ho, Karen S and Harward, Erin and Murtaza, Nadeem and others},\n  journal={The American Journal of Human Genetics},\n  volume={102},\n  number={2},\n  pages={278--295},\n  year={2018},\n  publisher={Elsevier}\n}\n\n
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\n \n\n \n \n \n \n \n TRTH-29. CONTEXT-SPECIFIC TUMOR SUPPRESSIVE FUNCTION OF THE CANONICAL WNT PATHWAY IN PEDIATRIC MEDULLOBLASTOMA HIGHLIGHTS A THERAPEUTIC STRATEGY FOR TREATMENT-REFRACTORY SUBGROUPS.\n \n \n \n\n\n \n Manoranjan, B.; Venugopal, C.; Kameda-Smith, M.; Bakhshinyan, D.; Subapanditha, M.; Doble, B.; and Singh, S.\n\n\n \n\n\n\n Neuro-oncology, 19(Suppl 4): iv58. 2017.\n \n\n\n\n
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@article{manoranjan2017trth,\n  title={TRTH-29. CONTEXT-SPECIFIC TUMOR SUPPRESSIVE FUNCTION OF THE CANONICAL WNT PATHWAY IN PEDIATRIC MEDULLOBLASTOMA HIGHLIGHTS A THERAPEUTIC STRATEGY FOR TREATMENT-REFRACTORY SUBGROUPS},\n  author={Manoranjan, Branavan and Venugopal, Chitra and Kameda-Smith, Michelle and Bakhshinyan, David and Subapanditha, Minomi and Doble, Bradley and Singh, Sheila},\n  journal={Neuro-oncology},\n  volume={19},\n  number={Suppl 4},\n  pages={iv58},\n  year={2017},\n  publisher={Oxford University Press}\n}\n\n
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\n \n\n \n \n \n \n \n Activated Wnt signaling for the treatment of recurrent medulloblastoma.\n \n \n \n\n\n \n Manoranjan, B.; Venugopal, C.; Pavlovic, Z.; Bakhshinyan, D.; Kameda-Smith, M.; Subapanditha, M.; Mahendram, S.; Moffat, J.; Doble, B. W; and Singh, S.\n\n\n \n\n\n\n 2017.\n \n\n\n\n
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@misc{manoranjan2017activated,\n  title={Activated Wnt signaling for the treatment of recurrent medulloblastoma},\n  author={Manoranjan, Branavan and Venugopal, Chitra and Pavlovic, Zvezdan and Bakhshinyan, David and Kameda-Smith, Michelle and Subapanditha, Minomi and Mahendram, Sujeivan and Moffat, Jason and Doble, Bradley W and Singh, Sheila},\n  year={2017},\n  publisher={American Association for Cancer Research}\n}\n\n
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\n \n\n \n \n \n \n \n A Single TCF Transcription Factor, Regardless of Its Activation Capacity, Is Sufficient for Effective Trilineage Differentiation of ESCs.\n \n \n \n\n\n \n Moreira, S.; Polena, E.; Gordon, V.; Abdulla, S.; Mahendram, S.; Cao, J.; Blais, A.; Wood, G. A; Dvorkin-Gheva, A.; and Doble, B. W\n\n\n \n\n\n\n Cell reports, 20(10): 2424–2438. 2017.\n \n\n\n\n
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@article{moreira2017single,\n  title={A Single TCF Transcription Factor, Regardless of Its Activation Capacity, Is Sufficient for Effective Trilineage Differentiation of ESCs},\n  author={Moreira, Steven and Polena, Enio and Gordon, Victor and Abdulla, Solen and Mahendram, Sujeivan and Cao, Jiayi and Blais, Alexandre and Wood, Geoffrey A and Dvorkin-Gheva, Anna and Doble, Bradley W},\n  journal={Cell reports},\n  volume={20},\n  number={10},\n  pages={2424--2438},\n  year={2017},\n  publisher={Cell Press}\n}\n\n
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\n \n\n \n \n \n \n \n CSIG-22. A CD133-Akt-Wnt SIGNALING AXIS PROVIDES FUNCTIONAL INSIGHT INTO THE ROLE OF CD133 IN GLIOBLASTOMA BRAIN TUMOR-INITIATING CELLS.\n \n \n \n\n\n \n Manoranjan, B.; Venugopal, C.; Mahendram, S.; Subapanditha, M.; Savage, N.; Qazi, M.; Vora, P.; Moffat, J.; Doble, B.; and Singh, S.\n\n\n \n\n\n\n Neuro-oncology, 19(Suppl 6): vi54. 2017.\n \n\n\n\n
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@article{manoranjan2017csig,\n  title={CSIG-22. A CD133-Akt-Wnt SIGNALING AXIS PROVIDES FUNCTIONAL INSIGHT INTO THE ROLE OF CD133 IN GLIOBLASTOMA BRAIN TUMOR-INITIATING CELLS},\n  author={Manoranjan, Branavan and Venugopal, Chitra and Mahendram, Sujeivan and Subapanditha, Minomi and Savage, Neil and Qazi, Maleeha and Vora, Parvez and Moffat, Jason and Doble, Bradley and Singh, Sheila},\n  journal={Neuro-oncology},\n  volume={19},\n  number={Suppl 6},\n  pages={vi54},\n  year={2017},\n  publisher={Oxford University Press}\n}\n\n
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\n \n\n \n \n \n \n \n Multimerin-1 Binds to Specific Motifs in Vessel Wall Collagens and Contributes to Thrombosis: Novel Insights Regarding the Mechanisms That Support Human and Mouse Platelet Adhesion.\n \n \n \n\n\n \n Leatherdale, A.; Parker, D.; Tasneem, S.; Wang, Y.; Bonna, A.; Gross, P. L; Ni, H.; Doble, B.; Farndale, R. W; and Hayward, C. P.\n\n\n \n\n\n\n Blood, 130(Supplement 1): 549–549. 2017.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{leatherdale2017multimerin,\n  title={Multimerin-1 Binds to Specific Motifs in Vessel Wall Collagens and Contributes to Thrombosis: Novel Insights Regarding the Mechanisms That Support Human and Mouse Platelet Adhesion},\n  author={Leatherdale, Alexander and Parker, D'Andra and Tasneem, Subia and Wang, Yiming and Bonna, Arkadiusz and Gross, Peter L and Ni, Heyu and Doble, Bradley and Farndale, Richard W and Hayward, Catherine PM},\n  journal={Blood},\n  volume={130},\n  number={Supplement 1},\n  pages={549--549},\n  year={2017},\n  publisher={American Society of Hematology}\n}\n\n
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\n \n\n \n \n \n \n \n STEM-21. CONTEXT-SPECIFIC TUMOR SUPPRESSIVE FUNCTION OF THE CANONICAL Wnt PATHWAY IN PEDIATRIC MEDULLOBLASTOMA HIGHLIGHTS A THERAPEUTIC STRATEGY FOR TREATMENT-REFRACTORY SUBGROUPS.\n \n \n \n\n\n \n Manoranjan, B.; Venugopal, C.; Kameda-Smith, M.; Bakhshinyan, D.; Subapanditha, M.; Doble, B.; and Singh, S.\n\n\n \n\n\n\n Neuro-oncology, 19(Suppl 6): vi230. 2017.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{manoranjan2017stem,\n  title={STEM-21. CONTEXT-SPECIFIC TUMOR SUPPRESSIVE FUNCTION OF THE CANONICAL Wnt PATHWAY IN PEDIATRIC MEDULLOBLASTOMA HIGHLIGHTS A THERAPEUTIC STRATEGY FOR TREATMENT-REFRACTORY SUBGROUPS},\n  author={Manoranjan, Branavan and Venugopal, Chitra and Kameda-Smith, Michelle and Bakhshinyan, David and Subapanditha, Minomi and Doble, Bradley and Singh, Sheila},\n  journal={Neuro-oncology},\n  volume={19},\n  number={Suppl 6},\n  pages={vi230},\n  year={2017},\n  publisher={Oxford University Press}\n}\n\n
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\n \n\n \n \n \n \n \n Disease models and prognostic tools for pre-leukemia and leukemia.\n \n \n \n\n\n \n Bhatia, M.; DOBLE, B. W.; GUEZGUEZ, B.; ALMAKADI, M. S.; and GARCIA-RODRIQUEZ, J. L.\n\n\n \n\n\n\n 2017.\n \n\n\n\n
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@misc{bhatia2017disease,\n  title={Disease models and prognostic tools for pre-leukemia and leukemia},\n  author={Bhatia, Mickie and DOBLE, Bradley Wayne and GUEZGUEZ, Borhane and ALMAKADI, Mohammed Saleh and GARCIA-RODRIQUEZ, Juan Luis},\n  year={2017}\n}\n\n
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\n  \n 2016\n \n \n (3)\n \n \n
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\n \n \n
\n \n\n \n \n \n \n \n GSK3 deficiencies in hematopoietic stem cells initiate pre-neoplastic state that is predictive of clinical outcomes of human acute leukemia.\n \n \n \n\n\n \n Guezguez, B.; Almakadi, M.; Benoit, Y. D; Shapovalova, Z.; Rahmig, S.; Fiebig-Comyn, A.; Casado, F. L; Tanasijevic, B.; Bresolin, S.; Masetti, R.; and others\n\n\n \n\n\n\n Cancer cell, 29(1): 61–74. 2016.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{guezguez2016gsk3,\n  title={GSK3 deficiencies in hematopoietic stem cells initiate pre-neoplastic state that is predictive of clinical outcomes of human acute leukemia},\n  author={Guezguez, Borhane and Almakadi, Mohammed and Benoit, Yannick D and Shapovalova, Zoya and Rahmig, Susann and Fiebig-Comyn, Aline and Casado, Fanny L and Tanasijevic, Borko and Bresolin, Silvia and Masetti, Riccardo and others},\n  journal={Cancer cell},\n  volume={29},\n  number={1},\n  pages={61--74},\n  year={2016},\n  publisher={Cell Press}\n}\n\n
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\n \n\n \n \n \n \n \n MB-22 ACTIVATED Wnt SIGNALING FOR THE THERAPEUTIC TARGETING OF TREATMENT-REFRACTORY MEDULLOBLASTOMA STEM CELLS.\n \n \n \n\n\n \n Manoranjan, B.; Mahendram, S.; Bakhshinyan, D.; Kameda-Smith, M.; Venugopal, C.; Doble, B.; and Singh, S.\n\n\n \n\n\n\n Neuro-Oncology, 18(suppl_3): iii101–iii101. 2016.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{manoranjan2016mb,\n  title={MB-22 ACTIVATED Wnt SIGNALING FOR THE THERAPEUTIC TARGETING OF TREATMENT-REFRACTORY MEDULLOBLASTOMA STEM CELLS},\n  author={Manoranjan, Branavan and Mahendram, Sujeivan and Bakhshinyan, David and Kameda-Smith, Michelle and Venugopal, Chitra and Doble, Bradley and Singh, Sheila},\n  journal={Neuro-Oncology},\n  volume={18},\n  number={suppl\\_3},\n  pages={iii101--iii101},\n  year={2016},\n  publisher={Oxford University Press}\n}\n\n
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\n \n\n \n \n \n \n \n OS4-161 Activated Wnt Signaling for the Therapeutic Targeting of Treatment-Refractory Medulloblastoma Stem Cells.\n \n \n \n\n\n \n Manoranjan, B; Mahendram, S; Bakhshinyan, D; Kameda-Smith, M; Venugopal, C; Doble, B.; and Singh, S.\n\n\n \n\n\n\n Canadian Journal of Neurological Sciences, 43(S4): S2–S3. 2016.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{manoranjan2016os4,\n  title={OS4-161 Activated Wnt Signaling for the Therapeutic Targeting of Treatment-Refractory Medulloblastoma Stem Cells},\n  author={Manoranjan, B and Mahendram, S and Bakhshinyan, D and Kameda-Smith, M and Venugopal, C and Doble, BW and Singh, SK},\n  journal={Canadian Journal of Neurological Sciences},\n  volume={43},\n  number={S4},\n  pages={S2--S3},\n  year={2016},\n  publisher={Cambridge University Press}\n}\n\n
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\n  \n 2015\n \n \n (5)\n \n \n
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\n \n \n
\n \n\n \n \n \n \n \n Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells.\n \n \n \n\n\n \n Meredith, G. D; D'Ippolito, A.; Dudas, M.; Zeidner, L. C; Hostetter, L.; Faulds, K.; Arnold, T. H; Popkie, A. P; Doble, B. W; Marnellos, G.; and others\n\n\n \n\n\n\n Molecular biology of the cell, 26(11): 2139–2150. 2015.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{meredith2015glycogen,\n  title={Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells},\n  author={Meredith, Gavin D and D'Ippolito, Anthony and Dudas, Miroslav and Zeidner, Leigh C and Hostetter, Logan and Faulds, Kelsie and Arnold, Thomas H and Popkie, Anthony P and Doble, Bradley W and Marnellos, George and others},\n  journal={Molecular biology of the cell},\n  volume={26},\n  number={11},\n  pages={2139--2150},\n  year={2015},\n  publisher={The American Society for Cell Biology}\n}\n\n
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\n \n\n \n \n \n \n \n MB-15 ACTIVATED Wnt SIGNALING TARGETS Sox2+ TREATMENT-REFRACTORY Shh-DEPENDENT MEDULLOBLASTOMA STEM CELLS.\n \n \n \n\n\n \n Manoranjan, B.; Venugopal, C.; Mahendram, S.; Moreira, S.; Hallett, R.; Vijayakumar, T.; Bakhshinyan, D.; McFarlane, N.; Hassell, J.; Doble, B.; and others\n\n\n \n\n\n\n Neuro-oncology, 17(suppl_3): iii23–iii23. 2015.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{manoranjan2015mb,\n  title={MB-15 ACTIVATED Wnt SIGNALING TARGETS Sox2+ TREATMENT-REFRACTORY Shh-DEPENDENT MEDULLOBLASTOMA STEM CELLS},\n  author={Manoranjan, Branavan and Venugopal, Chitra and Mahendram, Sujeivan and Moreira, Steven and Hallett, Robin and Vijayakumar, Thusyanth and Bakhshinyan, David and McFarlane, Nicole and Hassell, John and Doble, Bradley and others},\n  journal={Neuro-oncology},\n  volume={17},\n  number={suppl\\_3},\n  pages={iii23--iii23},\n  year={2015},\n  publisher={Oxford University Press}\n}\n\n
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\n \n\n \n \n \n \n \n Fine-tuning of the RIG-I-Like receptor/interferon regulatory factor 3-dependent antiviral innate immune response by the glycogen synthase kinase 3/$β$-catenin pathway.\n \n \n \n\n\n \n Khan, K. A.; Dô, F.; Marineau, A.; Doyon, P.; Clément, J.; Woodgett, J. R; Doble, B. W; and Servant, M. J\n\n\n \n\n\n\n Molecular and cellular biology, 35(17): 3029–3043. 2015.\n \n\n\n\n
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@article{khan2015fine,\n  title={Fine-tuning of the RIG-I-Like receptor/interferon regulatory factor 3-dependent antiviral innate immune response by the glycogen synthase kinase 3/$\\beta$-catenin pathway},\n  author={Khan, Kashif Aziz and D{\\^o}, Florence and Marineau, Alexandre and Doyon, Priscilla and Cl{\\'e}ment, Jean-Fran{\\c{c}}ois and Woodgett, James R and Doble, Bradley W and Servant, Marc J},\n  journal={Molecular and cellular biology},\n  volume={35},\n  number={17},\n  pages={3029--3043},\n  year={2015},\n  publisher={American Society for Microbiology 1752 N St., NW, Washington, DC}\n}\n\n
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\n \n\n \n \n \n \n \n Pyrvinium targets CD133 in human glioblastoma brain tumor–initiating cells.\n \n \n \n\n\n \n Venugopal, C.; Hallett, R.; Vora, P.; Manoranjan, B.; Mahendram, S.; Qazi, M. A; McFarlane, N.; Subapanditha, M.; Nolte, S. M; Singh, M.; and others\n\n\n \n\n\n\n Clinical Cancer Research, 21(23): 5324–5337. 2015.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{venugopal2015pyrvinium,\n  title={Pyrvinium targets CD133 in human glioblastoma brain tumor--initiating cells},\n  author={Venugopal, Chitra and Hallett, Robin and Vora, Parvez and Manoranjan, Branavan and Mahendram, Sujeivan and Qazi, Maleeha A and McFarlane, Nicole and Subapanditha, Minomi and Nolte, Sara M and Singh, Mohini and others},\n  journal={Clinical Cancer Research},\n  volume={21},\n  number={23},\n  pages={5324--5337},\n  year={2015},\n  publisher={American Association for Cancer Research}\n}\n\n
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\n \n\n \n \n \n \n \n STEM-23 Pyrvinium targets CD133 in human glioblastoma brain tumor-initiating cells.\n \n \n \n\n\n \n Venugopal, C.; Hallett, R.; Vora, P.; Manoranjan, B.; Mahendram, S.; Qazi, M.; McFarlane, N.; Subapanditha, M.; Nolte, S.; Singh, M.; and others\n\n\n \n\n\n\n Neuro-oncology, 17(suppl_5): v213–v213. 2015.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{venugopal2015stem,\n  title={STEM-23 Pyrvinium targets CD133 in human glioblastoma brain tumor-initiating cells},\n  author={Venugopal, Chitra and Hallett, Robin and Vora, Parvez and Manoranjan, Branavan and Mahendram, Sujeivan and Qazi, Maleeha and McFarlane, Nicole and Subapanditha, Minomi and Nolte, Sara and Singh, Mohini and others},\n  journal={Neuro-oncology},\n  volume={17},\n  number={suppl\\_5},\n  pages={v213--v213},\n  year={2015},\n  publisher={Oxford University Press}\n}\n\n
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\n  \n 2014\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n Gene expression profiling in mouse embryonic stem cells reveals glycogen synthase kinase-3-dependent targets of phosphatidylinositol 3-kinase and Wnt/$β$-catenin signaling pathways.\n \n \n \n\n\n \n Bartman, C. M; Egelston, J.; Kattula, S.; Zeidner, L. C; D’Ippolito, A.; Doble, B. W; and Phiel, C. J\n\n\n \n\n\n\n Frontiers in endocrinology, 5: 133. 2014.\n \n\n\n\n
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@article{bartman2014gene,\n  title={Gene expression profiling in mouse embryonic stem cells reveals glycogen synthase kinase-3-dependent targets of phosphatidylinositol 3-kinase and Wnt/$\\beta$-catenin signaling pathways},\n  author={Bartman, Colleen M and Egelston, Jennifer and Kattula, Sravya and Zeidner, Leigh C and D’Ippolito, Anthony and Doble, Bradley W and Phiel, Christopher J},\n  journal={Frontiers in endocrinology},\n  volume={5},\n  pages={133},\n  year={2014},\n  publisher={Frontiers}\n}\n\n
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\n  \n 2013\n \n \n (3)\n \n \n
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\n \n\n \n \n \n \n \n Medulloblastoma stem cells: modeling tumor heterogeneity.\n \n \n \n\n\n \n Manoranjan, B.; Venugopal, C.; McFarlane, N.; Doble, B. W; Dunn, S. E; Scheinemann, K.; and Singh, S. K\n\n\n \n\n\n\n Cancer letters, 338(1): 23–31. 2013.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{manoranjan2013medulloblastoma,\n  title={Medulloblastoma stem cells: modeling tumor heterogeneity},\n  author={Manoranjan, Branavan and Venugopal, Chitra and McFarlane, Nicole and Doble, Bradley W and Dunn, Sandra E and Scheinemann, Katrin and Singh, Sheila K},\n  journal={Cancer letters},\n  volume={338},\n  number={1},\n  pages={23--31},\n  year={2013},\n  publisher={Elsevier}\n}\n\n
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\n \n\n \n \n \n \n \n Ectopic $γ$-catenin Expression Partially Mimics the Effects of Stabilized $β$-catenin on Embryonic Stem Cell Differentiation.\n \n \n \n\n\n \n Mahendram, S.; Kelly, K. F.; Paez-Parent, S.; Mahmood, S.; Polena, E.; Cooney, A. J.; and Doble, B. W.\n\n\n \n\n\n\n PLoS ONE, 8(5): e65320. 2013.\n \n\n\n\n
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@article{mahendram2013ectopic,\n  title={Ectopic $\\gamma$-catenin Expression Partially Mimics the Effects of Stabilized $\\beta$-catenin on Embryonic Stem Cell Differentiation},\n  author={Mahendram, Sujeivan and Kelly, Kevin F. and Paez-Parent, Sabrina and Mahmood, Sharmeen and Polena, Enio and Cooney, Austin J. and Doble, Bradley W.},\n  journal={PLoS ONE},\n  volume={8},\n  number={5},\n  pages={e65320},\n  year={2013},\n  publisher={Public Library of Science}\n}\n\n
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\n \n\n \n \n \n \n \n The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin.\n \n \n \n\n\n \n Holowacz, T.; Alexson, T. O; Coles, B. L; Doble, B. W; Kelly, K. F; Woodgett, J. R; and Van Der Kooy, D.\n\n\n \n\n\n\n Biology open, 2(8): 812–821. 2013.\n \n\n\n\n
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@article{holowacz2013responses,\n  title={The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin},\n  author={Holowacz, Tamara and Alexson, Tania O and Coles, Brenda L and Doble, Bradley W and Kelly, Kevin F and Woodgett, James R and Van Der Kooy, Derek},\n  journal={Biology open},\n  volume={2},\n  number={8},\n  pages={812--821},\n  year={2013},\n  publisher={The Company of Biologists Bidder Building, 140 Cowley Road, Cambridge, CB4~…}\n}\n\n
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\n  \n 2012\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n Medulloblastoma stem cells: where development and cancer cross pathways.\n \n \n \n\n\n \n Manoranjan, B.; Venugopal, C.; McFarlane, N.; Doble, B. W; Dunn, S. E; Scheinemann, K.; and Singh, S. K\n\n\n \n\n\n\n Pediatric research, 71(2): 516–522. 2012.\n \n\n\n\n
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@article{manoranjan2012medulloblastoma,\n  title={Medulloblastoma stem cells: where development and cancer cross pathways},\n  author={Manoranjan, Branavan and Venugopal, Chitra and McFarlane, Nicole and Doble, Bradley W and Dunn, Sandra E and Scheinemann, Katrin and Singh, Sheila K},\n  journal={Pediatric research},\n  volume={71},\n  number={2},\n  pages={516--522},\n  year={2012},\n  publisher={Nature Publishing Group}\n}\n\n
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\n \n\n \n \n \n \n \n Effects of Ischemia on Cardiomyocyte.\n \n \n \n\n\n \n Tanguy, S.; Jeyaraman, M.; Doble, B. W; Jiang, Z.; Fandrich, R. R; and Kardami, E.\n\n\n \n\n\n\n Pathophysiology of Cardiovascular Disease, 10: 257. 2012.\n \n\n\n\n
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@article{tanguy2012effects,\n  title={Effects of Ischemia on Cardiomyocyte},\n  author={Tanguy, St{\\'e}phane and Jeyaraman, Madhumathy and Doble, Bradley W and Jiang, Zhisheng and Fandrich, Robert R and Kardami, Elissavet},\n  journal={Pathophysiology of Cardiovascular Disease},\n  volume={10},\n  pages={257},\n  year={2012},\n  publisher={Springer Science \\& Business Media}\n}\n\n
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\n  \n 2011\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n $β$-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism.\n \n \n \n\n\n \n Kelly, K. F; Ng, D. Y; Jayakumaran, G.; Wood, G. A; Koide, H.; and Doble, B. W\n\n\n \n\n\n\n Cell stem cell, 8(2): 214–227. 2011.\n \n\n\n\n
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@article{kelly2011beta,\n  title={$\\beta$-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism},\n  author={Kelly, Kevin F and Ng, Deborah Y and Jayakumaran, Gowtham and Wood, Geoffrey A and Koide, Hiroshi and Doble, Bradley W},\n  journal={Cell stem cell},\n  volume={8},\n  number={2},\n  pages={214--227},\n  year={2011},\n  publisher={Elsevier}\n}\n\n
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\n \n\n \n \n \n \n \n Molecular Mechanisms Underlying Pluripotency and Lineage Commitment–The Role of GSK-3.\n \n \n \n\n\n \n Doble, B. W; Kelly, K. F; and Woodgett, J. R\n\n\n \n\n\n\n Embryonic Stem Cells: Basic Biology to Bioengineering,369. 2011.\n \n\n\n\n
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@article{doble2011molecular,\n  title={Molecular Mechanisms Underlying Pluripotency and Lineage Commitment--The Role of GSK-3},\n  author={Doble, Bradley W and Kelly, Kevin F and Woodgett, James R},\n  journal={Embryonic Stem Cells: Basic Biology to Bioengineering},\n  pages={369},\n  year={2011},\n  publisher={BoD--Books on Demand}\n}\n\n
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\n  \n 2010\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n GSK-3$α$ directly regulates $β$-adrenergic signaling and the response of the heart to hemodynamic stress in mice.\n \n \n \n\n\n \n Zhou, J.; Lal, H.; Chen, X.; Shang, X.; Song, J.; Li, Y.; Kerkela, R.; Doble, B. W; MacAulay, K.; DeCaul, M.; and others\n\n\n \n\n\n\n The Journal of clinical investigation, 120(7): 2280–2291. 2010.\n \n\n\n\n
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@article{zhou2010gsk,\n  title={GSK-3$\\alpha$ directly regulates $\\beta$-adrenergic signaling and the response of the heart to hemodynamic stress in mice},\n  author={Zhou, Jibin and Lal, Hind and Chen, Xiongwen and Shang, Xiying and Song, Jianliang and Li, Yingxin and Kerkela, Risto and Doble, Bradley W and MacAulay, Katrina and DeCaul, Morgan and others},\n  journal={The Journal of clinical investigation},\n  volume={120},\n  number={7},\n  pages={2280--2291},\n  year={2010},\n  publisher={American Society for Clinical Investigation}\n}\n\n
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\n \n\n \n \n \n \n \n Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci.\n \n \n \n\n\n \n Popkie, A. P; Zeidner, L. C; Albrecht, A. M; D'Ippolito, A.; Eckardt, S.; Newsom, D. E; Groden, J.; Doble, B. W; Aronow, B.; McLaughlin, K J.; and others\n\n\n \n\n\n\n Journal of Biological Chemistry, 285(53): 41337–41347. 2010.\n \n\n\n\n
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@article{popkie2010phosphatidylinositol,\n  title={Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci},\n  author={Popkie, Anthony P and Zeidner, Leigh C and Albrecht, Ashley M and D'Ippolito, Anthony and Eckardt, Sigrid and Newsom, David E and Groden, Joanna and Doble, Bradley W and Aronow, Bruce and McLaughlin, K John and others},\n  journal={Journal of Biological Chemistry},\n  volume={285},\n  number={53},\n  pages={41337--41347},\n  year={2010},\n  publisher={Elsevier}\n}\n\n
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\n  \n 2009\n \n \n (7)\n \n \n
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\n \n\n \n \n \n \n \n GSK-3 is a master regulator of neural progenitor homeostasis.\n \n \n \n\n\n \n Kim, W.; Wang, X.; Wu, Y.; Doble, B. W; Patel, S.; Woodgett, J. R; and Snider, W. D\n\n\n \n\n\n\n Nature neuroscience, 12(11): 1390–1397. 2009.\n \n\n\n\n
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@article{kim2009gsk,\n  title={GSK-3 is a master regulator of neural progenitor homeostasis},\n  author={Kim, Woo-Yang and Wang, Xinshuo and Wu, Yaohong and Doble, Bradley W and Patel, Satish and Woodgett, James R and Snider, William D},\n  journal={Nature neuroscience},\n  volume={12},\n  number={11},\n  pages={1390--1397},\n  year={2009},\n  publisher={Nature Publishing Group}\n}\n\n
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\n \n\n \n \n \n \n \n Abnormalities in brain structure and behavior in GSK-3alpha mutant mice.\n \n \n \n\n\n \n Kaidanovich-Beilin, O.; Lipina, T. V; Takao, K.; Van Eede, M.; Hattori, S.; Laliberté, C.; Khan, M.; Okamoto, K.; Chambers, J. W; Fletcher, P. J; and others\n\n\n \n\n\n\n Molecular brain, 2(1): 1–23. 2009.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{kaidanovich2009abnormalities,\n  title={Abnormalities in brain structure and behavior in GSK-3alpha mutant mice},\n  author={Kaidanovich-Beilin, Oksana and Lipina, Tatiana V and Takao, Keizo and Van Eede, Matthijs and Hattori, Satoko and Lalibert{\\'e}, Christine and Khan, Mustafa and Okamoto, Kenichi and Chambers, John W and Fletcher, Paul J and others},\n  journal={Molecular brain},\n  volume={2},\n  number={1},\n  pages={1--23},\n  year={2009},\n  publisher={BioMed Central}\n}\n\n
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\n \n\n \n \n \n \n \n Exploring pluripotency with chemical genetics.\n \n \n \n\n\n \n Doble, B. W; and Woodgett, J. R\n\n\n \n\n\n\n Cell Stem Cell, 4(2): 98–100. 2009.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{doble2009exploring,\n  title={Exploring pluripotency with chemical genetics},\n  author={Doble, Bradley W and Woodgett, James R},\n  journal={Cell Stem Cell},\n  volume={4},\n  number={2},\n  pages={98--100},\n  year={2009},\n  publisher={Cell Press}\n}\n\n
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\n \n\n \n \n \n \n \n IL-17 receptor signaling inhibits C/EBP$β$ by sequential phosphorylation of the regulatory 2 domain.\n \n \n \n\n\n \n Shen, F.; Li, N.; Gade, P.; Kalvakolanu, D. V; Weibley, T.; Doble, B.; Woodgett, J. R; Wood, T. D; and Gaffen, S. L\n\n\n \n\n\n\n Science signaling, 2(59): ra8–ra8. 2009.\n \n\n\n\n
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@article{shen200917,\n  title={IL-17 receptor signaling inhibits C/EBP$\\beta$ by sequential phosphorylation of the regulatory 2 domain},\n  author={Shen, Fang and Li, Nan and Gade, Padmaja and Kalvakolanu, Dhananjaya V and Weibley, Timothy and Doble, Brad and Woodgett, James R and Wood, Troy D and Gaffen, Sarah L},\n  journal={Science signaling},\n  volume={2},\n  number={59},\n  pages={ra8--ra8},\n  year={2009},\n  publisher={American Association for the Advancement of Science}\n}\n\n
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\n \n\n \n \n \n \n \n Deletion of GSK-3 alpha, but Not GSK-3 beta, Defines an Essential Role in beta-Adrenergic Responsiveness and Identifies a Novel Strategy for beta-Blockade.\n \n \n \n\n\n \n Zhou, J.; Woulfe, K.; Chen, X.; Gao, E.; Fan, Q.; Li, Y.; Lal, H.; Farber, J. L; Shang, X.; Doble, B. W; and others\n\n\n \n\n\n\n In CIRCULATION RESEARCH, volume 105, pages E56–E56, 2009. LIPPINCOTT WILLIAMS & WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA\n \n\n\n\n
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@inproceedings{zhou2009deletion,\n  title={Deletion of GSK-3 alpha, but Not GSK-3 beta, Defines an Essential Role in beta-Adrenergic Responsiveness and Identifies a Novel Strategy for beta-Blockade},\n  author={Zhou, Jibin and Woulfe, Kathleen and Chen, Xiongwen and Gao, Erhe and Fan, Qian and Li, Yingxin and Lal, Hind and Farber, John L and Shang, Xiying and Doble, Bradley W and others},\n  booktitle={CIRCULATION RESEARCH},\n  volume={105},\n  number={12},\n  pages={E56--E56},\n  year={2009},\n  organization={LIPPINCOTT WILLIAMS \\& WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA}\n}\n\n
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\n \n\n \n \n \n \n \n Chambers John W; Fletcher Paul J; MacAulay Katrina; Doble Bradley W; Henkelman Mark; Miyakawa Tsuyoshi; Roder John; Woodgett James R.\n \n \n \n\n\n \n Christine, L.; Mustafa, K.; and Kenichi, O.\n\n\n \n\n\n\n Molecular brain, 2: 35. 2009.\n \n\n\n\n
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@article{christine2009chambers,\n  title={Chambers John W; Fletcher Paul J; MacAulay Katrina; Doble Bradley W; Henkelman Mark; Miyakawa Tsuyoshi; Roder John; Woodgett James R},\n  author={Christine, Laliberte and Mustafa, Khan and Kenichi, Okamoto},\n  journal={Molecular brain},\n  volume={2},\n  pages={35},\n  year={2009}\n}\n\n
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\n \n\n \n \n \n \n \n IL-1 7 r ecep tor signaling negatively r egulates C/E BP? by sequentialp hosp horylation of the r egulator y 2 d om ain.\n \n \n \n\n\n \n Shen, F; Li, N; Gade, P; Kalvakolanu, D.; Weibley, T; Doble, B; Woodgett, J.; Wood, T.; and Gaffen, S.\n\n\n \n\n\n\n Sci. Signal, 2. 2009.\n \n\n\n\n
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@article{shen20091,\n  title={IL-1 7 r ecep tor signaling negatively r egulates C/E BP? by sequentialp hosp horylation of the r egulator y 2 d om ain},\n  author={Shen, F and Li, N and Gade, P and Kalvakolanu, DV and Weibley, T and Doble, B and Woodgett, JR and Wood, TD and Gaffen, SL},\n  journal={Sci. Signal},\n  volume={2},\n  year={2009}\n}\n\n
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\n  \n 2008\n \n \n (10)\n \n \n
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\n \n\n \n \n \n \n \n The ground state of embryonic stem cell self-renewal.\n \n \n \n\n\n \n Ying, Q.; Wray, J.; Nichols, J.; Batlle-Morera, L.; Doble, B.; Woodgett, J.; Cohen, P.; and Smith, A.\n\n\n \n\n\n\n nature, 453(7194): 519–523. 2008.\n \n\n\n\n
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@article{ying2008ground,\n  title={The ground state of embryonic stem cell self-renewal},\n  author={Ying, Qi-Long and Wray, Jason and Nichols, Jennifer and Batlle-Morera, Laura and Doble, Bradley and Woodgett, James and Cohen, Philip and Smith, Austin},\n  journal={nature},\n  volume={453},\n  number={7194},\n  pages={519--523},\n  year={2008},\n  publisher={Nature Publishing Group}\n}\n\n
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\n \n\n \n \n \n \n \n Phosphorylation by p38 MAPK as an alternative pathway for GSK3$β$ inactivation.\n \n \n \n\n\n \n Thornton, T. M; Pedraza-Alva, G.; Deng, B.; Wood, C D.; Aronshtam, A.; Clements, J. L; Sabio, G.; Davis, R. J; Matthews, D. E; Doble, B.; and others\n\n\n \n\n\n\n Science, 320(5876): 667–670. 2008.\n \n\n\n\n
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@article{thornton2008phosphorylation,\n  title={Phosphorylation by p38 MAPK as an alternative pathway for GSK3$\\beta$ inactivation},\n  author={Thornton, Tina M and Pedraza-Alva, Gustavo and Deng, Bin and Wood, C David and Aronshtam, Alexander and Clements, James L and Sabio, Guadalupe and Davis, Roger J and Matthews, Dwight E and Doble, Bradley and others},\n  journal={Science},\n  volume={320},\n  number={5876},\n  pages={667--670},\n  year={2008},\n  publisher={American Association for the Advancement of Science}\n}\n\n
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\n \n\n \n \n \n \n \n Deletion of GSK-3$β$ in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation.\n \n \n \n\n\n \n Kerkela, R.; Kockeritz, L.; MacAulay, K.; Zhou, J.; Doble, B. W; Beahm, C.; Greytak, S.; Woulfe, K.; Trivedi, C. M; Woodgett, J. R; and others\n\n\n \n\n\n\n The Journal of clinical investigation, 118(11): 3609–3618. 2008.\n \n\n\n\n
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@article{kerkela2008deletion,\n  title={Deletion of GSK-3$\\beta$ in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation},\n  author={Kerkela, Risto and Kockeritz, Lisa and MacAulay, Katrina and Zhou, Jibin and Doble, Bradley W and Beahm, Cara and Greytak, Sarah and Woulfe, Kathleen and Trivedi, Chinmay M and Woodgett, James R and others},\n  journal={The Journal of clinical investigation},\n  volume={118},\n  number={11},\n  pages={3609--3618},\n  year={2008},\n  publisher={American Society for Clinical Investigation}\n}\n\n
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\n \n\n \n \n \n \n \n Tissue-specific role of glycogen synthase kinase 3$β$ in glucose homeostasis and insulin action.\n \n \n \n\n\n \n Patel, S.; Doble, B. W; MacAulay, K.; Sinclair, E. M; Drucker, D. J; and Woodgett, J. R\n\n\n \n\n\n\n Molecular and cellular biology, 28(20): 6314–6328. 2008.\n \n\n\n\n
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@article{patel2008tissue,\n  title={Tissue-specific role of glycogen synthase kinase 3$\\beta$ in glucose homeostasis and insulin action},\n  author={Patel, Satish and Doble, Bradley W and MacAulay, Katrina and Sinclair, Elaine M and Drucker, Daniel J and Woodgett, James R},\n  journal={Molecular and cellular biology},\n  volume={28},\n  number={20},\n  pages={6314--6328},\n  year={2008},\n  publisher={American Society for Microbiology}\n}\n\n
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\n \n\n \n \n \n \n \n Genetic deficiency of glycogen synthase kinase-3$β$ corrects diabetes in mouse models of insulin resistance.\n \n \n \n\n\n \n Tanabe, K.; Liu, Z.; Patel, S.; Doble, B. W; Li, L.; Cras-Méneur, C.; Martinez, S. C; Welling, C. M; White, M. F; Bernal-Mizrachi, E.; and others\n\n\n \n\n\n\n PLoS biology, 6(2): e37. 2008.\n \n\n\n\n
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@article{tanabe2008genetic,\n  title={Genetic deficiency of glycogen synthase kinase-3$\\beta$ corrects diabetes in mouse models of insulin resistance},\n  author={Tanabe, Katsuya and Liu, Zhonghao and Patel, Satish and Doble, Bradley W and Li, Lin and Cras-M{\\'e}neur, Corentin and Martinez, Sara C and Welling, Cris M and White, Morris F and Bernal-Mizrachi, Ernesto and others},\n  journal={PLoS biology},\n  volume={6},\n  number={2},\n  pages={e37},\n  year={2008},\n  publisher={Public Library of Science San Francisco, USA}\n}\n\n
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\n \n\n \n \n \n \n \n O1-04–06: Glycogen synthase kinase-3$β$ and the p25 activator of cyclin-dependent kinase-5 regulate axoplasmic transport of mitochondria by increasing their stationary behavior.\n \n \n \n\n\n \n Morel, M.; Dedecker, R.; Doble, B.; Cruz, J.; and Brion, J.\n\n\n \n\n\n\n Alzheimer's & Dementia, 4: T116–T116. 2008.\n \n\n\n\n
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@article{morel2008o1,\n  title={O1-04--06: Glycogen synthase kinase-3$\\beta$ and the p25 activator of cyclin-dependent kinase-5 regulate axoplasmic transport of mitochondria by increasing their stationary behavior},\n  author={Morel, Marina and Dedecker, Robert and Doble, Bradley and Cruz, Jonathan and Brion, Jean-Pierre},\n  journal={Alzheimer's \\& Dementia},\n  volume={4},\n  pages={T116--T116},\n  year={2008}\n}\n\n
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\n \n\n \n \n \n \n \n O1-03–02: Analyzing the endogenous roles of GSK-3 isoforms in APP processing in GSK-3 deficient cells.\n \n \n \n\n\n \n Popkie, A.; Buescher, J. L; Miranda, C. J; Kaspar, B. K; Phiel, C. J; and Doble, B. W\n\n\n \n\n\n\n Alzheimer's & Dementia, 4: T112–T112. 2008.\n \n\n\n\n
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@article{popkie2008o1,\n  title={O1-03--02: Analyzing the endogenous roles of GSK-3 isoforms in APP processing in GSK-3 deficient cells},\n  author={Popkie, Anthony and Buescher, Jessica L and Miranda, Carlos J and Kaspar, Brian K and Phiel, Christopher J and Doble, Bradley W},\n  journal={Alzheimer's \\& Dementia},\n  volume={4},\n  pages={T112--T112},\n  year={2008}\n}\n\n
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\n \n\n \n \n \n \n \n Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.\n \n \n \n\n\n \n Zeng, X.; Huang, H.; Tamai, K.; Zhang, X.; Harada, Y.; Yokota, C.; Almeida, K.; Wang, J.; Doble, B.; Woodgett, J.; and others\n\n\n \n\n\n\n . 2008.\n \n\n\n\n
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@article{zeng2008initiation,\n  title={Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions},\n  author={Zeng, Xin and Huang, He and Tamai, Keiko and Zhang, Xinjun and Harada, Yuko and Yokota, Chika and Almeida, Karla and Wang, Jianbo and Doble, Brad and Woodgett, Jim and others},\n  year={2008},\n  publisher={Oxford University Press for The Company of Biologists Limited}\n}\n\n
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\n \n\n \n \n \n \n \n Prevention of amino acid conversion in SILAC experiments with embryonic stem cells.\n \n \n \n\n\n \n Bendall, S. C; Hughes, C.; Stewart, M. H; Doble, B.; Bhatia, M.; and Lajoie, G. A\n\n\n \n\n\n\n Molecular & Cellular Proteomics, 7(9): 1587–1597. 2008.\n \n\n\n\n
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@article{bendall2008prevention,\n  title={Prevention of amino acid conversion in SILAC experiments with embryonic stem cells},\n  author={Bendall, Sean C and Hughes, Chris and Stewart, Morag H and Doble, Brad and Bhatia, Mickie and Lajoie, Gilles A},\n  journal={Molecular \\& Cellular Proteomics},\n  volume={7},\n  number={9},\n  pages={1587--1597},\n  year={2008},\n  publisher={Elsevier}\n}\n\n
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\n \n\n \n \n \n \n \n Deletion of Glycogen Synthase Kinase-3$α$ (GKS-3$α$) Causes a Glycogen Storage Cardiomyopathy.\n \n \n \n\n\n \n Zhou, J.; Kerkela, R.; Harris, D.; MacAulay, K.; Kocheritz, L.; Doble, B. W; Schneider, T.; Woulfe, K.; Gao, E.; Lei, Y.; and others\n\n\n \n\n\n\n 2008.\n \n\n\n\n
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@misc{zhou2008deletion,\n  title={Deletion of Glycogen Synthase Kinase-3$\\alpha$ (GKS-3$\\alpha$) Causes a Glycogen Storage Cardiomyopathy},\n  author={Zhou, Jibin and Kerkela, Risto and Harris, David and MacAulay, Katrina and Kocheritz, Lisa and Doble, Bradley W and Schneider, Timothy and Woulfe, Kathleen and Gao, Erhe and Lei, Yonghong and others},\n  year={2008},\n  publisher={Lippincott Williams \\& Wilkins}\n}\n\n
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\n \n\n \n \n \n \n \n Functional redundancy of GSK-3$α$ and GSK-3$β$ in Wnt/$β$-catenin signaling shown by using an allelic series of embryonic stem cell lines.\n \n \n \n\n\n \n Doble, B. W; Patel, S.; Wood, G. A; Kockeritz, L. K; and Woodgett, J. R\n\n\n \n\n\n\n Developmental cell, 12(6): 957–971. 2007.\n \n\n\n\n
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@article{doble2007functional,\n  title={Functional redundancy of GSK-3$\\alpha$ and GSK-3$\\beta$ in Wnt/$\\beta$-catenin signaling shown by using an allelic series of embryonic stem cell lines},\n  author={Doble, Bradley W and Patel, Satish and Wood, Geoffrey A and Kockeritz, Lisa K and Woodgett, James R},\n  journal={Developmental cell},\n  volume={12},\n  number={6},\n  pages={957--971},\n  year={2007},\n  publisher={Elsevier}\n}\n\n
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\n \n\n \n \n \n \n \n Glycogen synthase kinase 3$α$-specific regulation of murine hepatic glycogen metabolism.\n \n \n \n\n\n \n MacAulay, K.; Doble, B. W; Patel, S.; Hansotia, T.; Sinclair, E. M; Drucker, D. J; Nagy, A.; and Woodgett, J. R\n\n\n \n\n\n\n Cell metabolism, 6(4): 329–337. 2007.\n \n\n\n\n
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@article{macaulay2007glycogen,\n  title={Glycogen synthase kinase 3$\\alpha$-specific regulation of murine hepatic glycogen metabolism},\n  author={MacAulay, Katrina and Doble, Bradley W and Patel, Satish and Hansotia, Tanya and Sinclair, Elaine M and Drucker, Daniel J and Nagy, Andras and Woodgett, James R},\n  journal={Cell metabolism},\n  volume={6},\n  number={4},\n  pages={329--337},\n  year={2007},\n  publisher={Cell Press}\n}\n\n
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\n \n\n \n \n \n \n \n Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions.\n \n \n \n\n\n \n Doble, B. W; and Woodgett, J. R\n\n\n \n\n\n\n Cells Tissues Organs, 185(1-3): 73–84. 2007.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{doble2007role,\n  title={Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions},\n  author={Doble, Bradley W and Woodgett, James R},\n  journal={Cells Tissues Organs},\n  volume={185},\n  number={1-3},\n  pages={73--84},\n  year={2007},\n  publisher={Karger Publishers}\n}\n\n
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\n \n\n \n \n \n \n \n R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and $β$-catenin signaling.\n \n \n \n\n\n \n Wei, Q.; Yokota, C.; Semenov, M. V; Doble, B.; Woodgett, J.; and He, X.\n\n\n \n\n\n\n Journal of Biological Chemistry, 282(21): 15903–15911. 2007.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{wei2007r,\n  title={R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and $\\beta$-catenin signaling},\n  author={Wei, Qiou and Yokota, Chika and Semenov, Mikhail V and Doble, Brad and Woodgett, Jim and He, Xi},\n  journal={Journal of Biological Chemistry},\n  volume={282},\n  number={21},\n  pages={15903--15911},\n  year={2007},\n  publisher={Elsevier}\n}\n\n
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\n \n\n \n \n \n \n \n Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium.\n \n \n \n\n\n \n Kaladchibachi, S. A; Doble, B.; Anthopoulos, N.; Woodgett, J. R; and Manoukian, A. S\n\n\n \n\n\n\n Journal of circadian rhythms, 5(1): 1–12. 2007.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n
@article{kaladchibachi2007glycogen,\n  title={Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium},\n  author={Kaladchibachi, Sevag A and Doble, Brad and Anthopoulos, Norman and Woodgett, James R and Manoukian, Armen S},\n  journal={Journal of circadian rhythms},\n  volume={5},\n  number={1},\n  pages={1--12},\n  year={2007},\n  publisher={BioMed Central}\n}\n\n
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\n \n\n \n \n \n \n \n Targeted Deletion of Glycogen Synthase Kinase-3$α$ (GSK-3$α$) vs. GSK-3$β$ identifies unique isoform-specific effects on development and hypertrophy.\n \n \n \n\n\n \n Zhou, J.; Kerkela, R.; MaCauly, K.; Kockeritz, L.; Doble, B. W; Woulfe, K.; Gao, E.; Pesant, S.; Lei, Y.; Trivedi, C. M; and others\n\n\n \n\n\n\n 2007.\n \n\n\n\n
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@misc{zhou2007targeted,\n  title={Targeted Deletion of Glycogen Synthase Kinase-3$\\alpha$ (GSK-3$\\alpha$) vs. GSK-3$\\beta$ identifies unique isoform-specific effects on development and hypertrophy},\n  author={Zhou, Jibin and Kerkela, Risto and MaCauly, Katrina and Kockeritz, Lisa and Doble, Bradley W and Woulfe, Kathleen and Gao, Erhe and Pesant, Stéphanie and Lei, Yonghong and Trivedi, Chinmay M and others},\n  year={2007},\n  publisher={Lippincott Williams \\& Wilkins}\n}\n\n
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\n  \n 2006\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n Glycogen synthase kinase-3-an overview of an over-achieving protein kinase.\n \n \n \n\n\n \n Kockeritz, L.; Doble, B.; Patel, S.; and Woodgett, J. R\n\n\n \n\n\n\n Current drug targets, 7(11): 1377–1388. 2006.\n \n\n\n\n
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@article{kockeritz2006glycogen,\n  title={Glycogen synthase kinase-3-an overview of an over-achieving protein kinase},\n  author={Kockeritz, Lisa and Doble, Bradley and Patel, Satish and Woodgett, James R},\n  journal={Current drug targets},\n  volume={7},\n  number={11},\n  pages={1377--1388},\n  year={2006},\n  publisher={Bentham Science Publishers}\n}\n\n
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\n \n\n \n \n \n \n \n P3–307: Glycogen synthase kinase–3beta and the p25 activator of cyclin–dependent kinase–5 decrease neuritogenesis and fast axoplasmic transport in differentiated PC12 cells.\n \n \n \n\n\n \n Morel, M.; Leroy, K.; Doble, B.; Cruz, J.; Tsai, L.; Woodgett, J.; and Brion, J.\n\n\n \n\n\n\n Alzheimer's & Dementia, 2: S465–S465. 2006.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{morel2006p3,\n  title={P3--307: Glycogen synthase kinase--3beta and the p25 activator of cyclin--dependent kinase--5 decrease neuritogenesis and fast axoplasmic transport in differentiated PC12 cells},\n  author={Morel, Marina and Leroy, Karelle and Doble, Brad and Cruz, Jonathan and Tsai, Liu-Huei and Woodgett, Jim and Brion, Jean-Pierre},\n  journal={Alzheimer's \\& Dementia},\n  volume={2},\n  pages={S465--S465},\n  year={2006}\n}\n\n
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\n  \n 2005\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation.\n \n \n \n\n\n \n Zeng, X.; Tamai, K.; Doble, B.; Li, S.; Huang, H.; Habas, R.; Okamura, H.; Woodgett, J.; and He, X.\n\n\n \n\n\n\n Nature, 438(7069): 873–877. 2005.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{zeng2005dual,\n  title={A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation},\n  author={Zeng, Xin and Tamai, Keiko and Doble, Brad and Li, Shitao and Huang, He and Habas, Raymond and Okamura, Heidi and Woodgett, Jim and He, Xi},\n  journal={Nature},\n  volume={438},\n  number={7069},\n  pages={873--877},\n  year={2005},\n  publisher={Nature Publishing Group}\n}\n\n
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\n \n\n \n \n \n \n \n Genetic analysis of GSK-3 alpha and beta in conditional knockout mice and stem cells.\n \n \n \n\n\n \n Woodgett, J; Doble, B; Patel, S; and Kockeritz, L\n\n\n \n\n\n\n In NEUROPSYCHOPHARMACOLOGY, volume 30, pages S39–S40, 2005. NATURE PUBLISHING GROUP MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND\n \n\n\n\n
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@inproceedings{woodgett2005genetic,\n  title={Genetic analysis of GSK-3 alpha and beta in conditional knockout mice and stem cells},\n  author={Woodgett, J and Doble, B and Patel, S and Kockeritz, L},\n  booktitle={NEUROPSYCHOPHARMACOLOGY},\n  volume={30},\n  pages={S39--S40},\n  year={2005},\n  organization={NATURE PUBLISHING GROUP MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND}\n}\n\n
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\n  \n 2004\n \n \n (4)\n \n \n
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\n \n\n \n \n \n \n \n Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword?.\n \n \n \n\n\n \n Patel, S; Doble, B; and Woodgett, J.\n\n\n \n\n\n\n Biochemical Society Transactions, 32(5): 803–808. 2004.\n \n\n\n\n
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@article{patel2004glycogen,\n  title={Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword?},\n  author={Patel, S and Doble, B and Woodgett, JR},\n  journal={Biochemical Society Transactions},\n  volume={32},\n  number={5},\n  pages={803--808},\n  year={2004},\n  publisher={Portland Press Ltd.}\n}\n\n
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\n \n\n \n \n \n \n \n Phosphorylation of serine 262 in the gap junction protein connexin-43 regulates DNA synthesis in cell-cell contact forming cardiomyocytes.\n \n \n \n\n\n \n Doble, B. W; Dang, X.; Ping, P.; Fandrich, R. R; Nickel, B. E; Jin, Y.; Cattini, P. A; and Kardami, E.\n\n\n \n\n\n\n Journal of cell science, 117(3): 507–514. 2004.\n \n\n\n\n
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@article{doble2004phosphorylation,\n  title={Phosphorylation of serine 262 in the gap junction protein connexin-43 regulates DNA synthesis in cell-cell contact forming cardiomyocytes},\n  author={Doble, Bradley W and Dang, Xitong and Ping, Peipei and Fandrich, Robert R and Nickel, Barbara E and Jin, Yan and Cattini, Peter A and Kardami, Elissavet},\n  journal={Journal of cell science},\n  volume={117},\n  number={3},\n  pages={507--514},\n  year={2004},\n  publisher={Company of Biologists}\n}\n\n
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\n \n\n \n \n \n \n \n Effects of Ischemia on Cardiomyocyte Connexin-43 Distribution and Phosphorylation Studied in in vivo and in vitro Models.\n \n \n \n\n\n \n Tanguy, S.; Jeyaraman, M.; Doble, B. W; Jiang, Z.; Fandrich, R. R; and Kardami, E.\n\n\n \n\n\n\n In Pathophysiology of Cardiovascular Disease, pages 257–268. Springer, Boston, MA, 2004.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@incollection{tanguy2004effects,\n  title={Effects of Ischemia on Cardiomyocyte Connexin-43 Distribution and Phosphorylation Studied in in vivo and in vitro Models},\n  author={Tanguy, St{\\'e}phane and Jeyaraman, Madhumathy and Doble, Bradley W and Jiang, Zhisheng and Fandrich, Robert R and Kardami, Elissavet},\n  booktitle={Pathophysiology of Cardiovascular Disease},\n  pages={257--268},\n  year={2004},\n  publisher={Springer, Boston, MA}\n}\n\n
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\n \n\n \n \n \n \n \n Inhibition of TGF$β$ signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesis.\n \n \n \n\n\n \n Sheikh, F.; Hirst, C. J.; Jin, Y.; Bock, M. E; Fandrich, R. R; Nickel, B. E; Doble, B. W; Kardami, E.; and Cattini, P. A\n\n\n \n\n\n\n Cardiovascular research, 64(3): 516–525. 2004.\n \n\n\n\n
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@article{sheikh2004inhibition,\n  title={Inhibition of TGF$\\beta$ signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesis},\n  author={Sheikh, Farah and Hirst, Cheryl JA and Jin, Yan and Bock, Margaret E and Fandrich, Robert R and Nickel, Barbara E and Doble, Brad W and Kardami, Elissavet and Cattini, Peter A},\n  journal={Cardiovascular research},\n  volume={64},\n  number={3},\n  pages={516--525},\n  year={2004},\n  publisher={Elsevier Science}\n}\n\n
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\n  \n 2003\n \n \n (5)\n \n \n
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\n \n\n \n \n \n \n \n GSK-3: tricks of the trade for a multi-tasking kinase.\n \n \n \n\n\n \n Doble, B. W; and Woodgett, J. R\n\n\n \n\n\n\n Journal of cell science, 116(7): 1175–1186. 2003.\n \n\n\n\n
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@article{doble2003gsk,\n  title={GSK-3: tricks of the trade for a multi-tasking kinase},\n  author={Doble, Bradley W and Woodgett, James R},\n  journal={Journal of cell science},\n  volume={116},\n  number={7},\n  pages={1175--1186},\n  year={2003},\n  publisher={Company of Biologists}\n}\n\n
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\n \n\n \n \n \n \n \n The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growth.\n \n \n \n\n\n \n Dang, X.; Doble, B. W; and Kardami, E.\n\n\n \n\n\n\n Molecular and cellular biochemistry, 242(1): 35–38. 2003.\n \n\n\n\n
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@article{dang2003carboxy,\n  title={The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growth},\n  author={Dang, Xitong and Doble, Bradley W and Kardami, Elissavet},\n  journal={Molecular and cellular biochemistry},\n  volume={242},\n  number={1},\n  pages={35--38},\n  year={2003},\n  publisher={Kluwer Academic Publishers}\n}\n\n
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\n \n\n \n \n \n \n \n PKC-dependent phosphorylation may regulate the ability of connexin43 to inhibit DNA synthesis.\n \n \n \n\n\n \n Kardami, E; Banerji, S; Doble, B.; Dang, X; Fandrich, R.; Jin, Y; and Cattini, P.\n\n\n \n\n\n\n Cell communication & adhesion, 10(4-6): 293–297. 2003.\n \n\n\n\n
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@article{kardami2003pkc,\n  title={PKC-dependent phosphorylation may regulate the ability of connexin43 to inhibit DNA synthesis},\n  author={Kardami, E and Banerji, S and Doble, BW and Dang, X and Fandrich, RR and Jin, Y and Cattini, PA},\n  journal={Cell communication \\& adhesion},\n  volume={10},\n  number={4-6},\n  pages={293--297},\n  year={2003},\n  publisher={Taylor \\& Francis}\n}\n\n
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\n \n\n \n \n \n \n \n Index to Volume 242.\n \n \n \n\n\n \n Baetz, D; Bernard, M; Pinet, C; Tamareille, S; Chattou, S; El Banani, H; Coulombe, A; Feuvray, D; Bauer, E.; Kostin, S; and others\n\n\n \n\n\n\n Molecular and Cellular Biochemistry, 242: 189–191. 2003.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{baetz2003index,\n  title={Index to Volume 242},\n  author={Baetz, D and Bernard, M and Pinet, C and Tamareille, S and Chattou, S and El Banani, H and Coulombe, A and Feuvray, D and Bauer, EP and Kostin, S and others},\n  journal={Molecular and Cellular Biochemistry},\n  volume={242},\n  pages={189--191},\n  year={2003},\n  publisher={Springer}\n}\n\n
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\n \n\n \n \n \n \n \n Inhibition of cardiomyocyte DNA synthesis by connexin-43 is reversed by phosphorylation at ser-262, a PKC site.\n \n \n \n\n\n \n Kardami, E; Doble, B.; Dang, X.; Ping, P.; Fandrich, R.; Nickel, B; Jin, Y; and Cattini, P.\n\n\n \n\n\n\n In JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, volume 35, pages A32–A32, 2003. ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND\n \n\n\n\n
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@inproceedings{kardami2003inhibition,\n  title={Inhibition of cardiomyocyte DNA synthesis by connexin-43 is reversed by phosphorylation at ser-262, a PKC site.},\n  author={Kardami, E and Doble, BW and Dang, XT and Ping, PP and Fandrich, RR and Nickel, B and Jin, Y and Cattini, PA},\n  booktitle={JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY},\n  volume={35},\n  number={6},\n  pages={A32--A32},\n  year={2003},\n  organization={ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND}\n}\n\n
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\n  \n 2002\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n Acute protection of ischemic heart by FGF-2: involvement of FGF-2 receptors and protein kinase C.\n \n \n \n\n\n \n Jiang, Z.; Padua, R. R; Ju, H.; Doble, B. W; Jin, Y.; Hao, J.; Cattini, P. A; Dixon, I. M.; and Kardami, E.\n\n\n \n\n\n\n American Journal of Physiology-Heart and Circulatory Physiology, 282(3): H1071–H1080. 2002.\n \n\n\n\n
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@article{jiang2002acute,\n  title={Acute protection of ischemic heart by FGF-2: involvement of FGF-2 receptors and protein kinase C},\n  author={Jiang, Zhi-Sheng and Padua, Raymond R and Ju, Haisong and Doble, Bradley W and Jin, Yan and Hao, Jianming and Cattini, Peter A and Dixon, Ian MC and Kardami, Elissavet},\n  journal={American Journal of Physiology-Heart and Circulatory Physiology},\n  volume={282},\n  number={3},\n  pages={H1071--H1080},\n  year={2002},\n  publisher={American Physiological Society Bethesda, MD}\n}\n\n
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\n  \n 2001\n \n \n (4)\n \n \n
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\n \n\n \n \n \n \n \n CUG-initiated FGF-2 induces chromatin compaction in cultured cardiac myocytes and in vitro.\n \n \n \n\n\n \n Sun, G.; Doble, B. W; Sun, J.; Fandrich, R. R; Florkiewicz, R.; Kirshenbaum, L.; Davie, J. R; Cattini, P. A; and Kardami, E.\n\n\n \n\n\n\n Journal of cellular physiology, 186(3): 457–467. 2001.\n \n\n\n\n
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@article{sun2001cug,\n  title={CUG-initiated FGF-2 induces chromatin compaction in cultured cardiac myocytes and in vitro},\n  author={Sun, Guangping and Doble, Bradley W and Sun, Jian-Min and Fandrich, Robert R and Florkiewicz, Robert and Kirshenbaum, Lorrie and Davie, James R and Cattini, Peter A and Kardami, Elissavet},\n  journal={Journal of cellular physiology},\n  volume={186},\n  number={3},\n  pages={457--467},\n  year={2001},\n  publisher={John Wiley \\& Sons, Inc. New York}\n}\n\n
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\n \n\n \n \n \n \n \n Protein kinase C-epsilon mediates phorbol ester-induced phosphorylation of connexin-43.\n \n \n \n\n\n \n Doble, B.; Ping, P; Fandrich, R.; Cattini, P.; and Kardami, E\n\n\n \n\n\n\n Cell communication & adhesion, 8(4-6): 253–256. 2001.\n \n\n\n\n
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@article{doble2001protein,\n  title={Protein kinase C-epsilon mediates phorbol ester-induced phosphorylation of connexin-43},\n  author={Doble, BW and Ping, P and Fandrich, RR and Cattini, PA and Kardami, E},\n  journal={Cell communication \\& adhesion},\n  volume={8},\n  number={4-6},\n  pages={253--256},\n  year={2001},\n  publisher={Taylor \\& Francis}\n}\n\n
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\n \n\n \n \n \n \n \n Cardiac gap junctions, a target of growth factor signaling.\n \n \n \n\n\n \n Doble, B. W.\n\n\n \n\n\n\n . 2001.\n \n\n\n\n
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@article{doble2001cardiac,\n  title={Cardiac gap junctions, a target of growth factor signaling},\n  author={Doble, Bradley Wayne},\n  year={2001}\n}\n\n
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\n \n\n \n \n \n \n \n AJP-Heart Articles in PresS. Published on November 14, 2001 as DOI 10.1152/ajpheart. 00290.2001.\n \n \n \n\n\n \n Jiang, Z.; Padua, R. R; Ju, H.; Doble, B. W; Jin, Y.; Hao, J.; Cattini, P. A; Dixon, I. M.; Kardami, E.; and Kardami, E.\n\n\n \n\n\n\n . 2001.\n \n\n\n\n
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@article{jiang2001ajp,\n  title={AJP-Heart Articles in PresS. Published on November 14, 2001 as DOI 10.1152/ajpheart. 00290.2001},\n  author={Jiang, Zhi-Sheng and Padua, Raymond R and Ju, Haisong and Doble, Bradley W and Jin, Yan and Hao, Jianming and Cattini, Peter A and Dixon, Ian MC and Kardami, Elissavet and Kardami, Elissavet},\n  year={2001}\n}\n\n
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\n  \n 2000\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n The $ɛ$ subtype of protein kinase C is required for cardiomyocyte connexin-43 phosphorylation.\n \n \n \n\n\n \n Doble, B. W; Ping, P.; and Kardami, E.\n\n\n \n\n\n\n Circulation research, 86(3): 293–301. 2000.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n
@article{doble2000varepsilon,\n  title={The $\\varepsilon$ subtype of protein kinase C is required for cardiomyocyte connexin-43 phosphorylation},\n  author={Doble, Bradley W and Ping, Peipei and Kardami, Elissavet},\n  journal={Circulation research},\n  volume={86},\n  number={3},\n  pages={293--301},\n  year={2000},\n  publisher={Lippincott Williams \\& Wilkins}\n}\n\n
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\n \n\n \n \n \n \n \n Phosphorylation of a specific serine on connexin-43 affects cardiomyocyte proliferation.\n \n \n \n\n\n \n Doble, B.; Dang, X.; Jin, Y; Cattini, P.; and Kardami, E\n\n\n \n\n\n\n In MOLECULAR BIOLOGY OF THE CELL, volume 11, pages 224A–225A, 2000. AMER SOC CELL BIOLOGY 8120 WOODMONT AVE, STE 750, BETHESDA, MD 20814-2755 USA\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n
@inproceedings{doble2000phosphorylation,\n  title={Phosphorylation of a specific serine on connexin-43 affects cardiomyocyte proliferation},\n  author={Doble, BW and Dang, XT and Jin, Y and Cattini, PA and Kardami, E},\n  booktitle={MOLECULAR BIOLOGY OF THE CELL},\n  volume={11},\n  pages={224A--225A},\n  year={2000},\n  organization={AMER SOC CELL BIOLOGY 8120 WOODMONT AVE, STE 750, BETHESDA, MD 20814-2755 USA}\n}\n\n
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\n  \n 1998\n \n \n (3)\n \n \n
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\n \n\n \n \n \n \n \n FGF-2-induced negative inotropism and cardioprotection are inhibited by chelerythrine: involvement of sarcolemmal calcium-independent protein kinase C.\n \n \n \n\n\n \n Padua, R. R; Merle, P.; Doble, B. W; Yu, C.; Zahradka, P.; Pierce, G. N; Panagia, V.; and Kardami, E.\n\n\n \n\n\n\n Journal of molecular and cellular cardiology, 30(12): 2695–2709. 1998.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
\n
@article{padua1998fgf,\n  title={FGF-2-induced negative inotropism and cardioprotection are inhibited by chelerythrine: involvement of sarcolemmal calcium-independent protein kinase C},\n  author={Padua, Raymond R and Merle, Pierre-Laurent and Doble, Bradley W and Yu, Chang-Hua and Zahradka, Peter and Pierce, Grant N and Panagia, Vincenzo and Kardami, Elissavet},\n  journal={Journal of molecular and cellular cardiology},\n  volume={30},\n  number={12},\n  pages={2695--2709},\n  year={1998},\n  publisher={Academic Press}\n}\n\n
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\n \n\n \n \n \n \n \n Cardiomyocyte gap junctions: A target of growth-promoting signaling.\n \n \n \n\n\n \n Kardami, E.; and Doble, B. W\n\n\n \n\n\n\n Trends in cardiovascular medicine, 8(4): 180–187. 1998.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{kardami1998cardiomyocyte,\n  title={Cardiomyocyte gap junctions: A target of growth-promoting signaling},\n  author={Kardami, Elissavet and Doble, Bradley W},\n  journal={Trends in cardiovascular medicine},\n  volume={8},\n  number={4},\n  pages={180--187},\n  year={1998},\n  publisher={Elsevier}\n}\n\n
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\n \n\n \n \n \n \n \n Involvement of protein kinase C-ein mediating growth factor induced phosphorylation of connexin43 at gap junctions of the intact cardiomyocyte.\n \n \n \n\n\n \n Doble, B.; Merle, P.; and Kardami, E\n\n\n \n\n\n\n In Circulation, volume 98, pages 677–677, 1998. LIPPINCOTT WILLIAMS & WILKINS 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 USA\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@inproceedings{doble1998involvement,\n  title={Involvement of protein kinase C-ein mediating growth factor induced phosphorylation of connexin43 at gap junctions of the intact cardiomyocyte},\n  author={Doble, BW and Merle, PL and Kardami, E},\n  booktitle={Circulation},\n  volume={98},\n  number={17},\n  pages={677--677},\n  year={1998},\n  organization={LIPPINCOTT WILLIAMS \\& WILKINS 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106 USA}\n}\n\n
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\n  \n 1997\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n Selective monoclonal antibody recognition and cellular localization of an unphosphorylated form of connexin43.\n \n \n \n\n\n \n Nagy, J.; Li, W.; Roy, C; Doble, B.; Gilchrist, J.; Kardami, E; and Hertzberg, E.\n\n\n \n\n\n\n Experimental cell research, 236(1): 127–136. 1997.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{nagy1997selective,\n  title={Selective monoclonal antibody recognition and cellular localization of an unphosphorylated form of connexin43},\n  author={Nagy, JI and Li, WEI and Roy, C and Doble, BW and Gilchrist, JS and Kardami, E and Hertzberg, EL},\n  journal={Experimental cell research},\n  volume={236},\n  number={1},\n  pages={127--136},\n  year={1997},\n  publisher={Academic Press}\n}\n\n
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\n\n\n
\n \n\n \n \n \n \n \n Fibroblast Growth Factor-2 Stimulates Connexin-43 Phosphorylation and Decreases Metabolic Coupling of Cardiomyocytes by Protein Kinase C But Not Mitogen Activated Protein Kinase-Dependent Signaling.\n \n \n \n\n\n \n Doble, B. W; and Kardami, E.\n\n\n \n\n\n\n Circulation, 96(8S). 1997.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{doble1997fibroblast,\n  title={Fibroblast Growth Factor-2 Stimulates Connexin-43 Phosphorylation and Decreases Metabolic Coupling of Cardiomyocytes by Protein Kinase C But Not Mitogen Activated Protein Kinase-Dependent Signaling},\n  author={Doble, Bradley W and Kardami, Elissavet},\n  journal={Circulation},\n  volume={96},\n  number={8S},\n  year={1997}\n}\n\n
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\n  \n 1996\n \n \n (2)\n \n \n
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\n \n \n
\n \n\n \n \n \n \n \n Fibroblast growth factor-2 decreases metabolic coupling and stimulates phosphorylation as well as masking of connexin43 epitopes in cardiac myocytes.\n \n \n \n\n\n \n Doble, B. W; Chen, Y.; Bosc, D. G; Litchfield, D. W; and Kardami, E.\n\n\n \n\n\n\n Circulation research, 79(4): 647–658. 1996.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{doble1996fibroblast,\n  title={Fibroblast growth factor-2 decreases metabolic coupling and stimulates phosphorylation as well as masking of connexin43 epitopes in cardiac myocytes},\n  author={Doble, Bradley W and Chen, Yijing and Bosc, Denis G and Litchfield, David W and Kardami, Elissavet},\n  journal={Circulation research},\n  volume={79},\n  number={4},\n  pages={647--658},\n  year={1996},\n  publisher={Lippincott Williams \\& Wilkins}\n}\n\n
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\n\n\n\n
\n\n\n
\n \n\n \n \n \n \n \n Evidence that FGF-2 may induce association of connexin-43 with tyrosine-phosphorylated protein (s) in cardiac myocytes, leading to decreased intercellular communication.\n \n \n \n\n\n \n Doble, B.; Bosc, D; Litchfield, D; Hertzberg, E; and Kardami, E\n\n\n \n\n\n\n Biochemistry and Cell Biology, 74(4): 601–601. 1996.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{doble1996evidence,\n  title={Evidence that FGF-2 may induce association of connexin-43 with tyrosine-phosphorylated protein (s) in cardiac myocytes, leading to decreased intercellular communication},\n  author={Doble, BW and Bosc, D and Litchfield, D and Hertzberg, E and Kardami, E},\n  journal={Biochemistry and Cell Biology},\n  volume={74},\n  number={4},\n  pages={601--601},\n  year={1996},\n  publisher={Ottawa: National Research Council of Canada= Conseil national de recherches~…}\n}\n\n
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\n  \n 1995\n \n \n (2)\n \n \n
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\n \n \n
\n \n\n \n \n \n \n \n Basic fibroblast growth factor stimulates connexin-43 expression and intercellular communication of cardiac fibroblasts.\n \n \n \n\n\n \n Doble, B. W; and Kardami, E.\n\n\n \n\n\n\n Molecular and cellular biochemistry, 143(1): 81–87. 1995.\n \n\n\n\n
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@article{doble1995basic,\n  title={Basic fibroblast growth factor stimulates connexin-43 expression and intercellular communication of cardiac fibroblasts},\n  author={Doble, Bradley W and Kardami, Elissavet},\n  journal={Molecular and cellular biochemistry},\n  volume={143},\n  number={1},\n  pages={81--87},\n  year={1995},\n  publisher={Kluwer Academic Publishers}\n}\n\n
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\n \n\n \n \n \n \n \n Regulation of basic fibroblast growth factor (bFGF) and FGF receptors in the heart.\n \n \n \n\n\n \n Kardami, E.; Liu, L.; Kishore, S; Pasumarthi, B; Doble, B. W; and Cattini, P. A\n\n\n \n\n\n\n Annals of the New York Academy of Sciences-Paper Edition, 752: 353–369. 1995.\n \n\n\n\n
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@article{kardami1995regulation,\n  title={Regulation of basic fibroblast growth factor (bFGF) and FGF receptors in the heart},\n  author={Kardami, Elissavet and Liu, Lei and Kishore, S and Pasumarthi, B and Doble, Bradley W and Cattini, Peter A},\n  journal={Annals of the New York Academy of Sciences-Paper Edition},\n  volume={752},\n  pages={353--369},\n  year={1995},\n  publisher={New York: New York Academy of Sciences.}\n}\n\n
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\n  \n 1994\n \n \n (2)\n \n \n
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\n \n \n
\n \n\n \n \n \n \n \n Over-expression of CUG-or AUG-initiated forms of basic fibroblast growth factor in cardiac myocytes results in similar effects on mitosis and protein synthesis but distinct nuclear morphologies.\n \n \n \n\n\n \n Pasumarthi, K. B.; Doble, B. W; Kardami, E.; and Cattini, P. A\n\n\n \n\n\n\n Journal of molecular and cellular cardiology, 26(8): 1045–1060. 1994.\n \n\n\n\n
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@article{pasumarthi1994over,\n  title={Over-expression of CUG-or AUG-initiated forms of basic fibroblast growth factor in cardiac myocytes results in similar effects on mitosis and protein synthesis but distinct nuclear morphologies},\n  author={Pasumarthi, Kishore BS and Doble, Bradley W and Kardami, Elissavet and Cattini, Peter A},\n  journal={Journal of molecular and cellular cardiology},\n  volume={26},\n  number={8},\n  pages={1045--1060},\n  year={1994},\n  publisher={Academic Press}\n}\n\n
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\n \n\n \n \n \n \n \n BASIC FIBROBLAST GROWTH-FACTOR (BFGF) INCREASES CONNEXIN43 (CX43) MESSENGER-RNA ACCUMULATION AND CELL-CELL COMMUNICATION IN CARDIAC FIBROBLASTS.\n \n \n \n\n\n \n DOBLE, B; and KARDAMI, E\n\n\n \n\n\n\n In FASEB JOURNAL, volume 8, pages A51–A51, 1994. FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@inproceedings{doble1994basic,\n  title={BASIC FIBROBLAST GROWTH-FACTOR (BFGF) INCREASES CONNEXIN43 (CX43) MESSENGER-RNA ACCUMULATION AND CELL-CELL COMMUNICATION IN CARDIAC FIBROBLASTS},\n  author={DOBLE, B and KARDAMI, E},\n  booktitle={FASEB JOURNAL},\n  volume={8},\n  number={4},\n  pages={A51--A51},\n  year={1994},\n  organization={FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998}\n}\n\n
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\n  \n 1993\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n Perinatal phenotype and hypothyroidism are associated with elevated levels of 21.5-to 22-kDa basic fibroblast growth factor in cardiac ventricles.\n \n \n \n\n\n \n Liu, L.; Doble, B. W; and Kardami, E.\n\n\n \n\n\n\n Developmental biology, 157(2): 507–516. 1993.\n \n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{liu1993perinatal,\n  title={Perinatal phenotype and hypothyroidism are associated with elevated levels of 21.5-to 22-kDa basic fibroblast growth factor in cardiac ventricles},\n  author={Liu, Lei and Doble, Bradley W and Kardami, Elissavet},\n  journal={Developmental biology},\n  volume={157},\n  number={2},\n  pages={507--516},\n  year={1993},\n  publisher={Academic Press}\n}\n\n
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\n \n\n \n \n \n \n \n Basic fibroblast growth factor in cardiac myocytes: expression and effects.\n \n \n \n\n\n \n Kardami, E.; Padua, R. R; Pasumarthi, K. B. S; Liu, L.; Doble, B. W; Davey, S. E; and Cattini, P. A\n\n\n \n\n\n\n In Growth factors and the cardiovascular system, pages 55–75. Springer, Boston, MA, 1993.\n \n\n\n\n
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@incollection{kardami1993basic,\n  title={Basic fibroblast growth factor in cardiac myocytes: expression and effects},\n  author={Kardami, Elissavet and Padua, Raymond R and Pasumarthi, Kishore Babu S and Liu, Lei and Doble, Bradley W and Davey, Sarah E and Cattini, Peter A},\n  booktitle={Growth factors and the cardiovascular system},\n  pages={55--75},\n  year={1993},\n  publisher={Springer, Boston, MA}\n}\n\n
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\n  \n 1992\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n OVER EXPRESSION OF BASIC FIBROBLAST GROWTH-FACTOR (BFGF) IN CARDIAC MYOCYTES IS ASSOCIATED WITH NUCLEAR FRAGMENTATION.\n \n \n \n\n\n \n Pasumarthi, S.; Doble, B; Liu, L; Bock, M; Kardami, E; and Cattini, P.\n\n\n \n\n\n\n In FASEB JOURNAL, volume 6, pages A1078–A1078, 1992. FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998\n \n\n\n\n
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@inproceedings{pasumarthi1992over,\n  title={OVER EXPRESSION OF BASIC FIBROBLAST GROWTH-FACTOR (BFGF) IN CARDIAC MYOCYTES IS ASSOCIATED WITH NUCLEAR FRAGMENTATION},\n  author={Pasumarthi, SKB and Doble, B and Liu, L and Bock, M and Kardami, E and Cattini, PA},\n  booktitle={FASEB JOURNAL},\n  volume={6},\n  number={4},\n  pages={A1078--A1078},\n  year={1992},\n  organization={FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998}\n}\n\n
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\n  \n 1991\n \n \n (3)\n \n \n
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\n \n\n \n \n \n \n \n Biochemical and ultrastructural evidence for the association of basic fibroblast growth factor with cardiac gap junctions.\n \n \n \n\n\n \n Kardami, E; Stoski, R.; Doble, B.; Yamamoto, T; Hertzberg, E.; and Nagy, J.\n\n\n \n\n\n\n Journal of Biological Chemistry, 266(29): 19551–19557. 1991.\n \n\n\n\n
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@article{kardami1991biochemical,\n  title={Biochemical and ultrastructural evidence for the association of basic fibroblast growth factor with cardiac gap junctions.},\n  author={Kardami, E and Stoski, RM and Doble, BW and Yamamoto, T and Hertzberg, EL and Nagy, JI},\n  journal={Journal of Biological Chemistry},\n  volume={266},\n  number={29},\n  pages={19551--19557},\n  year={1991},\n  publisher={Elsevier}\n}\n\n
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\n \n\n \n \n \n \n \n Basic fibroblast growth factor in cultured cardiac myocytes.\n \n \n \n\n\n \n Kardami, E.; Liu, L.; and Doble, B. W\n\n\n \n\n\n\n Ann NY Acad Sci, 638: 244–255. 1991.\n \n\n\n\n
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@article{kardami1991basic,\n  title={Basic fibroblast growth factor in cultured cardiac myocytes},\n  author={Kardami, Elissavet and Liu, Lei and Doble, Bradley W},\n  journal={Ann NY Acad Sci},\n  volume={638},\n  pages={244--255},\n  year={1991}\n}\n\n
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\n \n\n \n \n \n \n \n Basic fibroblast growth factor in development and after isoproterenol-induced injury in the rat heart.\n \n \n \n\n\n \n Padua, R. R; Doble, B. W; Liu, L.; and Kardami, E.\n\n\n \n\n\n\n Journal of Molecular and Cellular Cardiology, 23: S90. 1991.\n \n\n\n\n
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@article{padua1991basic,\n  title={Basic fibroblast growth factor in development and after isoproterenol-induced injury in the rat heart},\n  author={Padua, Raymond R and Doble, Bradley W and Liu, Lei and Kardami, Elissavet},\n  journal={Journal of Molecular and Cellular Cardiology},\n  volume={23},\n  pages={S90},\n  year={1991},\n  publisher={Academic Press}\n}\n\n
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\n  \n 1990\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n Calcium protects pituitary basic fibroblast growth factors from limited proteolysis by co-purifying proteases.\n \n \n \n\n\n \n Doble, B. W; Fandrich, R. R; Liu, L.; Padua, R. R; and Kardami, E.\n\n\n \n\n\n\n Biochemical and biophysical research communications, 173(3): 1116–1122. 1990.\n \n\n\n\n
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@article{doble1990calcium,\n  title={Calcium protects pituitary basic fibroblast growth factors from limited proteolysis by co-purifying proteases},\n  author={Doble, Bradley W and Fandrich, Robert R and Liu, Lei and Padua, Raymond R and Kardami, Elissavet},\n  journal={Biochemical and biophysical research communications},\n  volume={173},\n  number={3},\n  pages={1116--1122},\n  year={1990},\n  publisher={Elsevier}\n}\n\n
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\n  \n 1988\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n Nucleotide sequence of katG, encoding catalase HPI of Escherichia coli.\n \n \n \n\n\n \n Triggs-Raine, B. L; Doble, B.; Mulvey, M.; Sorby, P.; and Loewen, P.\n\n\n \n\n\n\n Journal of bacteriology, 170(9): 4415–4419. 1988.\n \n\n\n\n
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@article{triggs1988nucleotide,\n  title={Nucleotide sequence of katG, encoding catalase HPI of Escherichia coli},\n  author={Triggs-Raine, Barbara L and Doble, BW and Mulvey, MR and Sorby, PA and Loewen, PC},\n  journal={Journal of bacteriology},\n  volume={170},\n  number={9},\n  pages={4415--4419},\n  year={1988}\n}\n\n
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\n \n\n \n \n \n \n \n Genetic analysis of the Wnt signaling pathway in stem cell differentiation and cancer.\n \n \n \n\n\n \n Woodgett, J.; Doble, B; and Patel, S\n\n\n \n\n\n\n . .\n \n\n\n\n
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@article{woodgettgenetic,\n  title={Genetic analysis of the Wnt signaling pathway in stem cell differentiation and cancer},\n  author={Woodgett, JR and Doble, B and Patel, S}\n}\n\n
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\n \n\n \n \n \n \n \n Supplemental Data Functional Redundancy of GSK-3$α$ and GSK-3$β$ in Wnt/$β$-Catenin Signaling Shown by Using an Allelic Series of Embryonic Stem Cell Lines.\n \n \n \n\n\n \n Doble, B. W; Patel, S.; Wood, G. A; Kockeritz, L. K; and Woodgett, J. R\n\n\n \n\n\n\n . .\n \n\n\n\n
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@article{doblesupplemental,\n  title={Supplemental Data Functional Redundancy of GSK-3$\\alpha$ and GSK-3$\\beta$ in Wnt/$\\beta$-Catenin Signaling Shown by Using an Allelic Series of Embryonic Stem Cell Lines},\n  author={Doble, Bradley W and Patel, Satish and Wood, Geoffrey A and Kockeritz, Lisa K and Woodgett, James R}\n}\n\n
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