\n \n \n
\n
\n \n 2022\n \n \n (3)\n \n \n
\n
\n \n \n
\n\n\n
\n
\n\n \n \n \n \n \n \n Modeling and measuring glucose diffusion and consumption by colorectal cancer spheroids in hanging drops using integrated biosensors.\n \n \n \n \n\n\n \n Rousset, N.; Sandoval, R. L.; Modena, M. M.; Hierlemann, A.; and Misun, P. M\n\n\n \n\n\n\n
Microsystems & nanoengineering, 8(1): 1–18. 2022.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{rousset2022modeling,\n title={Modeling and measuring glucose diffusion and consumption by colorectal cancer spheroids in hanging drops using integrated biosensors},\n author={Rousset, Nassim and Sandoval, Rub{\\'e}n L{\\'o}pez and Modena, Mario Matteo and Hierlemann, Andreas and Misun, Patrick M},\n journal={Microsystems \\& nanoengineering},\n volume={8},\n number={1},\n pages={1--18},\n year={2022},\n publisher={Nature Publishing Group},\n doi = {10.1038/s41378-021-00348-w},\n URL = {https://doi.org/10.1038/s41378-021-00348-w},\n eprint = {https://doi.org/10.1038/s41378-021-00348-w}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n \n Live cell microscopy: From image to insight.\n \n \n \n \n\n\n \n Cuny, A. P.; Schlottmann, F. P.; Ewald, J. C.; Pelet, S.; and Schmoller, K. M.\n\n\n \n\n\n\n
Biophysics Reviews, 3(2): 021302. 2022.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n \n \n 1 download\n \n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{cuny2022live,\nauthor = {Cuny,Andreas P. and Schlottmann,Fabian P. and Ewald,Jennifer C. and Pelet,Serge and Schmoller,Kurt M. },\ntitle = {Live cell microscopy: From image to insight},\njournal = {Biophysics Reviews},\nvolume = {3},\nnumber = {2},\npages = {021302},\nyear = {2022},\npublisher={AIP Publishing LLC},\ndoi = {10.1063/5.0082799},\nURL = {https://doi.org/10.1063/5.0082799},\neprint = {https://doi.org/10.1063/5.0082799}\n}\n\n
\n
\n\n\n\n
\n\n\n\n\n\n
\n
\n\n
\n
\n \n 2021\n \n \n (4)\n \n \n
\n
\n \n \n
\n
\n\n \n \n \n \n \n \n Permeation Studies across Symmetric and Asymmetric Membranes in Microdroplet Arrays.\n \n \n \n \n\n\n \n Bachler, S.; Ort, M.; Krämer, S. D; and Dittrich, P. S\n\n\n \n\n\n\n
Analytical chemistry, 93(12): 5137–5144. 2021.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n \n \n 1 download\n \n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{bachler2021permeation,\n title={Permeation Studies across Symmetric and Asymmetric Membranes in Microdroplet Arrays},\n author={Bachler, Simon and Ort, Marion and Krämer, Stefanie D and Dittrich, Petra S},\n journal={Analytical chemistry},\n volume={93},\n number={12},\n pages={5137--5144},\n year={2021},\n publisher={ACS Publications},\n doi = {10.1021/acs.analchem.0c04939},\n URL = {https://doi.org/10.1021/acs.analchem.0c04939},\n eprint = {https://doi.org/10.1021/acs.analchem.0c04939}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n \n Rapid prototyping and design of cybergenetic single-cell controllers.\n \n \n \n \n\n\n \n Kumar, S.; Rullan, M.; and Khammash, M.\n\n\n \n\n\n\n
Nature communications, 12(1): 1–13. 2021.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{kumar2021rapid,\n title={Rapid prototyping and design of cybergenetic single-cell controllers},\n author={Kumar, Sant and Rullan, Marc and Khammash, Mustafa},\n journal={Nature communications},\n volume={12},\n number={1},\n pages={1--13},\n year={2021},\n publisher={Nature Publishing Group},\n doi = {10.1038/s41467-021-25754-6},\n URL = {https://doi.org/10.1038/s41467-021-25754-6},\n eprint = {https://doi.org/10.1038/s41467-021-25754-6}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n \n Cell region fingerprints enable highly precise single-cell tracking and lineage reconstruction.\n \n \n \n \n\n\n \n Cuny, A. P; Ponti, A.; Kündig, T.; Rudolf, F.; and Stelling, J.\n\n\n \n\n\n\n
bioRxiv. 2021.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{cuny2021cell,\n title={Cell region fingerprints enable highly precise single-cell tracking and lineage reconstruction},\n author={Cuny, Andreas P and Ponti, Aaron and K{\\"u}ndig, Tomas and Rudolf, Fabian and Stelling, J{\\"o}rg},\n journal={bioRxiv},\n year={2021},\n publisher={Cold Spring Harbor Laboratory},\n doi = {10.1101/2021.10.26.465883},\n URL = {https://doi.org/10.1101/2021.10.26.465883},\n eprint = {https://doi.org/10.1101/2021.10.26.465883}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n\n\n\n\n\n
\n
\n\n
\n
\n \n 2020\n \n \n (7)\n \n \n
\n
\n \n \n
\n
\n\n \n \n \n \n \n \n DeLTA: Automated cell segmentation, tracking, and lineage reconstruction using deep learning.\n \n \n \n \n\n\n \n Lugagne, J.; Lin, H.; and Dunlop, M. J\n\n\n \n\n\n\n
PLoS computational biology, 16(4): e1007673. 2020.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{lugagne2020delta,\n title={DeLTA: Automated cell segmentation, tracking, and lineage reconstruction using deep learning},\n author={Lugagne, Jean-Baptiste and Lin, Haonan and Dunlop, Mary J},\n journal={PLoS computational biology},\n volume={16},\n number={4},\n pages={e1007673},\n year={2020},\n publisher={Public Library of Science San Francisco, CA USA},\n doi = {10.1371/journal.pcbi.1007673},\n URL = {https://doi.org/10.1371/journal.pcbi.1007673},\n eprint = {https://doi.org/10.1371/journal.pcbi.1007673}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n\n\n
\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n \n Preventing photomorbidity in long-term multi-color fluorescence imaging of Saccharomyces cerevisiae and S. pombe.\n \n \n \n \n\n\n \n Schmidt, G. W; Cuny, A. P; and Rudolf, F.\n\n\n \n\n\n\n
G3: Genes, Genomes, Genetics, 10(12): 4373–4385. 2020.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{schmidt2020preventing,\n title={Preventing photomorbidity in long-term multi-color fluorescence imaging of Saccharomyces cerevisiae and S. pombe},\n author={Schmidt, Gregor W and Cuny, Andreas P and Rudolf, Fabian},\n journal={G3: Genes, Genomes, Genetics},\n volume={10},\n number={12},\n pages={4373--4385},\n year={2020},\n publisher={Oxford University Press},\n doi = {10.1534/g3.120.401465},\n URL = {https://doi.org/10.1534/g3.120.401465},\n eprint = {https://doi.org/10.1534/g3.120.401465}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n Biological patterning in networks of interacting cells.\n \n \n \n\n\n \n Perkins, M. L.\n\n\n \n\n\n\n Ph.D. Thesis, 2020.\n
\n\n
\n\n
\n\n
\n\n \n\n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@phdthesis{perkins2020biological,\n title={Biological patterning in networks of interacting cells},\n author={Perkins, Melinda Liu},\n year={2020},\n publisher={University of California, Berkeley}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n\n\n\n\n\n
\n
\n\n
\n
\n \n 2019\n \n \n (2)\n \n \n
\n
\n \n \n
\n
\n\n \n \n \n \n \n \n A simple and flexible computational framework for inferring sources of heterogeneity from single-cell dynamics.\n \n \n \n \n\n\n \n Dharmarajan, L.; Kaltenbach, H.; Rudolf, F.; and Stelling, J.\n\n\n \n\n\n\n
Cell systems, 8(1): 15–26. 2019.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{dharmarajan2019simple,\n title={A simple and flexible computational framework for inferring sources of heterogeneity from single-cell dynamics},\n author={Dharmarajan, Lekshmi and Kaltenbach, Hans-Michael and Rudolf, Fabian and Stelling, Joerg},\n journal={Cell systems},\n volume={8},\n number={1},\n pages={15--26},\n year={2019},\n publisher={Elsevier},\n doi = {10.1016/j.cels.2018.12.007},\n URL = {https://doi.org/10.1016/j.cels.2018.12.007},\n eprint = {https://doi.org/10.1016/j.cels.2018.12.007}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n\n\n\n\n\n
\n
\n\n
\n
\n \n 2018\n \n \n (4)\n \n \n
\n
\n \n \n
\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n \n The CellClamper: a convenient microfluidic device for time-lapse imaging of yeast.\n \n \n \n \n\n\n \n Schmidt, G. W; Frey, O.; and Rudolf, F.\n\n\n \n\n\n\n In
Genome Instability, pages 537–555. Springer, 2018.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@incollection{schmidt2018cellclamper,\n title={The CellClamper: a convenient microfluidic device for time-lapse imaging of yeast},\n author={Schmidt, Gregor W and Frey, Olivier and Rudolf, Fabian},\n booktitle={Genome Instability},\n pages={537--555},\n year={2018},\n publisher={Springer},\n doi = {10.1007/978-1-4939-7306-4_36},\n URL = {https://doi.org/10.1007/978-1-4939-7306-4_36},\n eprint = {https://doi.org/10.1007/978-1-4939-7306-4_36}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n \n Fabrication and operation of microfluidic hanging-drop networks.\n \n \n \n \n\n\n \n Misun, P. M; Birchler, A. K; Lang, M.; Hierlemann, A.; and Frey, O.\n\n\n \n\n\n\n In
Cell-Based Microarrays, pages 183–202. Springer, 2018.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@incollection{misun2018fabrication,\n title={Fabrication and operation of microfluidic hanging-drop networks},\n author={Misun, Patrick M and Birchler, Axel K and Lang, Moritz and Hierlemann, Andreas and Frey, Olivier},\n booktitle={Cell-Based Microarrays},\n pages={183--202},\n year={2018},\n publisher={Springer},\n doi = {10.1007/978-1-4939-7792-5_15},\n URL = {https://doi.org/10.1007/978-1-4939-7792-5_15},\n eprint = {https://doi.org/10.1007/978-1-4939-7792-5_15}\n}\n\n
\n
\n\n\n\n
\n\n\n\n\n\n
\n
\n\n
\n
\n \n 2017\n \n \n (3)\n \n \n
\n
\n \n \n
\n
\n\n \n \n \n \n \n \n Optogenetic single-cell control of transcription achieves mrna tunability and reduced variability.\n \n \n \n \n\n\n \n Rullan, M.; Benzinger, D.; Schmidt, G. W; Gupta, A.; Milias-Argeitis, A.; and Khammash, M.\n\n\n \n\n\n\n
BioRxiv,142893. 2017.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{rullan2017optogenetic,\n title={Optogenetic single-cell control of transcription achieves mrna tunability and reduced variability},\n author={Rullan, Marc and Benzinger, Dirk and Schmidt, Gregor W and Gupta, Ankit and Milias-Argeitis, Andreas and Khammash, Mustafa},\n journal={BioRxiv},\n pages={142893},\n year={2017},\n publisher={Cold Spring Harbor Laboratory},\n doi = {10.1016/j.molcel.2018.04.012},\n URL = {https://doi.org/10.1016/j.molcel.2018.04.012},\n eprint = {https://doi.org/10.1016/j.molcel.2018.04.012}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n 3D High-content screening of organoids for drug discovery.\n \n \n \n\n\n \n Li, L; and LaBarbera, D.\n\n\n \n\n\n\n . 2017.\n
\n\n
\n\n
\n\n
\n\n \n\n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{li20173d,\n title={3D High-content screening of organoids for drug discovery},\n author={Li, L and LaBarbera, DV},\n year={2017},\n publisher={Elsevier}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n \n Microfluidic hydrogel hanging-drop network for high-resolution microscopy of 3D microtissues.\n \n \n \n \n\n\n \n Aeby, E. A; Misun, P. M; Müller, M.; Renggli, K.; Hierlemann, A.; and Frey, O.\n\n\n \n\n\n\n In
2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), pages 269–272, 2017. IEEE\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@inproceedings{aeby2017microfluidic,\n title={Microfluidic hydrogel hanging-drop network for high-resolution microscopy of 3D microtissues},\n author={Aeby, Elise A and Misun, Patrick M and M{\\"u}ller, Marius and Renggli, Kasper and Hierlemann, Andreas and Frey, Olivier},\n booktitle={2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)},\n pages={269--272},\n year={2017},\n organization={IEEE},\n doi = {10.1002/adbi.201800054},\n URL = {https://doi.org/10.1002/adbi.201800054},\n eprint = {https://doi.org/10.1002/adbi.201800054}\n}\n\n
\n
\n\n\n\n
\n\n\n\n\n\n
\n
\n\n
\n
\n \n 2016\n \n \n (2)\n \n \n
\n
\n \n \n
\n
\n\n \n \n \n \n \n \n Challenges in long-term imaging and quantification of single-cell dynamics.\n \n \n \n \n\n\n \n Skylaki, S.; Hilsenbeck, O.; and Schroeder, T.\n\n\n \n\n\n\n
Nature Biotechnology, 34(11): 1137–1144. 2016.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{skylaki2016challenges,\n title={Challenges in long-term imaging and quantification of single-cell dynamics},\n author={Skylaki, Stavroula and Hilsenbeck, Oliver and Schroeder, Timm},\n journal={Nature Biotechnology},\n volume={34},\n number={11},\n pages={1137--1144},\n year={2016},\n publisher={Nature Publishing Group},\n doi = {10.1038/nbt.3713},\n URL = {https://doi.org/10.1038/nbt.3713},\n eprint = {https://doi.org/10.1038/nbt.3713}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n \n A shuttle vector series for precise genetic engineering of Saccharomyces cerevisiae.\n \n \n \n \n\n\n \n Gnügge, R.; Liphardt, T.; and Rudolf, F.\n\n\n \n\n\n\n
Yeast, 33(3): 83–98. 2016.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{gnugge2016shuttle,\n title={A shuttle vector series for precise genetic engineering of Saccharomyces cerevisiae},\n author={Gn{\\"u}gge, Robert and Liphardt, Thomas and Rudolf, Fabian},\n journal={Yeast},\n volume={33},\n number={3},\n pages={83--98},\n year={2016},\n publisher={Wiley Online Library},\n doi = {10.1002/yea.3144},\n URL = {https://doi.org/10.1002/yea.3144},\n eprint = {https://doi.org/10.1002/yea.3144}\n}\n\n
\n
\n\n\n\n
\n\n\n\n\n\n
\n
\n\n
\n
\n \n 2015\n \n \n (1)\n \n \n
\n
\n \n \n
\n
\n\n \n \n \n \n \n \n Engineering of synthetic gene regulatory networks in Saccharomyces cerevisiae.\n \n \n \n \n\n\n \n Gnügge, R. J.\n\n\n \n\n\n\n Ph.D. Thesis, ETH Zurich, 2015.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@phdthesis{gnugge2015engineering,\n title={Engineering of synthetic gene regulatory networks in Saccharomyces cerevisiae},\n author={Gn{\\"u}gge, Robert Julius},\n year={2015},\n school={ETH Zurich},\n doi = {10.3929/ethz-a-010603388},\n URL = {https://doi.org/10.3929/ethz-a-010603388},\n eprint = {https://doi.org/10.3929/ethz-a-010603388}\n}\n\n
\n
\n\n\n\n
\n\n\n\n\n\n
\n
\n\n
\n
\n \n 2013\n \n \n (2)\n \n \n
\n
\n \n \n
\n
\n\n \n \n \n \n \n \n Probing cellular processes by long-term live imaging–historic problems and current solutions.\n \n \n \n \n\n\n \n Coutu, D. L; and Schroeder, T.\n\n\n \n\n\n\n
Journal of cell science, 126(17): 3805–3815. 2013.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@article{coutu2013probing,\n title={Probing cellular processes by long-term live imaging--historic problems and current solutions},\n author={Coutu, Daniel L and Schroeder, Timm},\n journal={Journal of cell science},\n volume={126},\n number={17},\n pages={3805--3815},\n year={2013},\n publisher={The Company of Biologists Bidder Building, 140 Cowley Road, Cambridge},\n doi = {10.1242/jcs.118349},\n URL = {https://doi.org/10.1242/jcs.118349},\n eprint = {https://doi.org/10.1242/jcs.118349}\n}\n\n
\n
\n\n\n\n
\n\n\n
\n
\n\n \n \n \n \n \n \n Implementation of a closed-loop microscopy pipeline to stitch and segment images of growing cell populations.\n \n \n \n \n\n\n \n Kumar, S. K. S.\n\n\n \n\n\n\n Master's thesis, ETH Zurich, 2013.\n
\n\n
\n\n
\n\n
\n\n \n \n
Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n
@mastersthesis{kumar2013implementation,\n title={Implementation of a closed-loop microscopy pipeline to stitch and segment images of growing cell populations},\n author={Kumar, Sri Krishna Suresh},\n year={2013},\n school={ETH Zurich},\n doi = {10.3929/ethz-a-009935780},\n URL = {https://doi.org/10.3929/ethz-a-009935780},\n eprint = {https://doi.org/10.3929/ethz-a-009935780}\n}\n\n
\n
\n\n\n\n
\n\n\n\n\n\n
\n
\n\n
\n
\n \n undefined\n \n \n (1)\n \n \n
\n
\n \n \n
\n
\n\n \n \n \n \n \n .\n \n \n \n\n\n \n \n\n\n \n\n\n\n . .\n
\n\n
\n\n
\n\n
\n\n \n\n \n\n \n link\n \n \n\n bibtex\n \n\n \n\n \n \n \n 9 downloads\n \n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
\n\n\n\n
\n\n\n\n\n\n
\n
\n\n\n\n\n