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\n  \n 2022\n \n \n (1)\n \n \n
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\n \n\n \n \n \n \n \n \n Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’.\n \n \n \n \n\n\n \n Barnett, A.; Beasley, R.; Buchan, C.; Chien, J.; Farah, C. S.; King, G.; McDonald, C. F.; Miller, B.; Munsif, M.; Psirides, A.; Reid, L.; Roberts, M.; Smallwood, N.; and Smith, S.\n\n\n \n\n\n\n Respirology, 27(4): 262–276. April 2022.\n \n\n\n\n
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@article{barnett_thoracic_2022,\n\ttitle = {Thoracic {Society} of {Australia} and {New} {Zealand} {Position} {Statement} on {Acute} {Oxygen} {Use} in {Adults}: ‘{Swimming} between the flags’},\n\tvolume = {27},\n\tissn = {1323-7799, 1440-1843},\n\tshorttitle = {Thoracic {Society} of {Australia} and {New} {Zealand} {Position} {Statement} on {Acute} {Oxygen} {Use} in {Adults}},\n\turl = {https://onlinelibrary.wiley.com/doi/10.1111/resp.14218},\n\tdoi = {10.1111/resp.14218},\n\tlanguage = {en},\n\tnumber = {4},\n\turldate = {2022-03-27},\n\tjournal = {Respirology},\n\tauthor = {Barnett, Adrian and Beasley, Richard and Buchan, Catherine and Chien, Jimmy and Farah, Claude S. and King, Gregory and McDonald, Christine F. and Miller, Belinda and Munsif, Maitri and Psirides, Alex and Reid, Lynette and Roberts, Mary and Smallwood, Natasha and Smith, Sheree},\n\tmonth = apr,\n\tyear = {2022},\n\tpages = {262--276},\n}\n\n
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\n  \n 2021\n \n \n (8)\n \n \n
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\n \n\n \n \n \n \n \n \n Audit of oxygen administration to achieve a target oxygen saturation range in acutely unwell medical patients.\n \n \n \n \n\n\n \n Harper, J.; Kearns, N.; Bird, G.; McLachlan, R.; Eathorne, A.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Postgraduate Medical Journal,postgradmedj–2020–139511. February 2021.\n \n\n\n\n
\n\n\n\n \n \n \"AuditPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n  \n \n 2 downloads\n \n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{harper_audit_2021,\n\ttitle = {Audit of oxygen administration to achieve a target oxygen saturation range in acutely unwell medical patients},\n\tissn = {0032-5473, 1469-0756},\n\turl = {https://pmj.bmj.com/lookup/doi/10.1136/postgradmedj-2020-139511},\n\tdoi = {10.1136/postgradmedj-2020-139511},\n\tabstract = {Purpose of the study\n              \n                To evaluate documentation of a target oxygen saturation (SpO\n                2\n                ) range and ability to achieve this range in acutely unwell inpatients.\n              \n            \n            \n              Study design\n              \n                In this single-centre audit, patients with discharge diagnoses of pneumonia, heart failure and exacerbation of asthma or COPD admitted to Wellington Regional Hospital, New Zealand between 1 June 2019 and 31 August 2019 who received oxygen were identified. In those with a documented target SpO\n                2\n                range, the proportion of SpO\n                2\n                measurements in the observation chart which were within, above and below range were determined as well as the maximum and minimum SpO\n                2\n                . Regression analysis was performed to determine whether these outcomes were influenced by the prescribed range, high-dependency care or the number of adjustments to oxygen administration.\n              \n            \n            \n              Results\n              \n                268 admissions were screened. Of the 100 eligible admissions who received oxygen, a target SpO\n                2\n                range was documented in 62. The mean (SD) proportion of SpO\n                2\n                measurements within range was 56.2 (30.6)\\%. A hypercapnic target SpO\n                2\n                range was associated with a higher probability of an SpO\n                2\n                above range; multivariate OR 5.34 (95\\% CI 1.65 to 17.3, p=0.006) and a lower probability of an SpO\n                2\n                below range; multivariate OR 0.25 (95\\% CI 0.08 to 0.80) p=0.02. The mean (SD) maximum SpO\n                2\n                was similar in those with a target range of 92\\%–96\\% versus a hypercapnic range; 96.2 (3.0)\\% and 95.2 (3.4)\\%, respectively.\n              \n            \n            \n              Conclusions\n              \n                Oxygen prescription and delivery in this clinical setting was suboptimal. SpO\n                2\n                values above the designated range are common, particularly in patients with a hypercapnic target range.},\n\tlanguage = {en},\n\turldate = {2022-03-04},\n\tjournal = {Postgraduate Medical Journal},\n\tauthor = {Harper, James and Kearns, Nethmi and Bird, Grace and McLachlan, Robert and Eathorne, Allie and Weatherall, Mark and Beasley, Richard},\n\tmonth = feb,\n\tyear = {2021},\n\tpages = {postgradmedj--2020--139511},\n}\n\n
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\n Purpose of the study To evaluate documentation of a target oxygen saturation (SpO 2 ) range and ability to achieve this range in acutely unwell inpatients. Study design In this single-centre audit, patients with discharge diagnoses of pneumonia, heart failure and exacerbation of asthma or COPD admitted to Wellington Regional Hospital, New Zealand between 1 June 2019 and 31 August 2019 who received oxygen were identified. In those with a documented target SpO 2 range, the proportion of SpO 2 measurements in the observation chart which were within, above and below range were determined as well as the maximum and minimum SpO 2 . Regression analysis was performed to determine whether these outcomes were influenced by the prescribed range, high-dependency care or the number of adjustments to oxygen administration. Results 268 admissions were screened. Of the 100 eligible admissions who received oxygen, a target SpO 2 range was documented in 62. The mean (SD) proportion of SpO 2 measurements within range was 56.2 (30.6)%. A hypercapnic target SpO 2 range was associated with a higher probability of an SpO 2 above range; multivariate OR 5.34 (95% CI 1.65 to 17.3, p=0.006) and a lower probability of an SpO 2 below range; multivariate OR 0.25 (95% CI 0.08 to 0.80) p=0.02. The mean (SD) maximum SpO 2 was similar in those with a target range of 92%–96% versus a hypercapnic range; 96.2 (3.0)% and 95.2 (3.4)%, respectively. Conclusions Oxygen prescription and delivery in this clinical setting was suboptimal. SpO 2 values above the designated range are common, particularly in patients with a hypercapnic target range.\n
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\n \n\n \n \n \n \n \n \n Determination of oxygen saturation compared to a prescribed target range using continuous pulse oximetry in acutely unwell medical patients.\n \n \n \n \n\n\n \n Harper, J. C. P.; Semprini, R.; Kearns, N. A.; Hatter, L.; Bird, G. E.; Braithwaite, I.; Eathorne, A.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n BMC Pulmonary Medicine, 21(1): 332. December 2021.\n \n\n\n\n
\n\n\n\n \n \n \"DeterminationPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n  \n \n 1 download\n \n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{harper_determination_2021,\n\ttitle = {Determination of oxygen saturation compared to a prescribed target range using continuous pulse oximetry in acutely unwell medical patients},\n\tvolume = {21},\n\tissn = {1471-2466},\n\turl = {https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-021-01700-6},\n\tdoi = {10.1186/s12890-021-01700-6},\n\tabstract = {Abstract\n            \n              Background\n              \n                Both inadequate and excessive administration of oxygen to acutely unwell patients results in risk of harm. Guidelines recommend titration of oxygen to achieve a target oxygen saturation (SpO\n                2\n                ) range. Information regarding whether this is being achieved is limited.\n              \n            \n            \n              Methods\n              \n                In this two-centre non-interventional study we used continuous pulse oximetry in acutely unwell medical patients over a 24-h period to determine the proportion of time spent with SpO\n                2\n                within the prescribed target range and whether this is influenced by the target range, age, care in a high-dependency area and the number of oxygen adjustments.\n              \n            \n            \n              Results\n              \n                Eighty participants were included in the analysis. The mean (SD) proportion of time spent in target range was 55.6\\% (23.6), this was lower in those with a reduced hypercapnic target range (88–92\\% or below) compared to those with a range of 92–96\\%; difference − 13.1\\% (95\\% CI − 3.0 to − 23.2),\n                P\n                 = 0.012. The proportion of time spent above range was 16.2\\% (22.9); this was higher in those with a reduced hypercapnic range; difference 21.6\\% (31.4 to 12),\n                P\n                 {\\textless} 0.001. The proportion of time below range was 28.4\\% (25.2); there was no difference between target ranges. The proportion of time spent in range was higher for those in a high dependency area in the multivariate model; difference 15.5\\% (95\\% CI 2.3 to 28.7),\n                P\n                 = 0.02.\n              \n            \n            \n              Conclusions\n              \n                Medical patients receiving oxygen in a ward setting spend significant periods of time with SpO\n                2\n                both above and below the prescribed target range while receiving oxygen therapy.},\n\tlanguage = {en},\n\tnumber = {1},\n\turldate = {2022-03-04},\n\tjournal = {BMC Pulmonary Medicine},\n\tauthor = {Harper, James C. P. and Semprini, Ruth and Kearns, Nethmi A. and Hatter, Lee and Bird, Grace E. and Braithwaite, Irene and Eathorne, Allie and Weatherall, Mark and Beasley, Richard},\n\tmonth = dec,\n\tyear = {2021},\n\tpages = {332},\n}\n\n
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\n Abstract Background Both inadequate and excessive administration of oxygen to acutely unwell patients results in risk of harm. Guidelines recommend titration of oxygen to achieve a target oxygen saturation (SpO 2 ) range. Information regarding whether this is being achieved is limited. Methods In this two-centre non-interventional study we used continuous pulse oximetry in acutely unwell medical patients over a 24-h period to determine the proportion of time spent with SpO 2 within the prescribed target range and whether this is influenced by the target range, age, care in a high-dependency area and the number of oxygen adjustments. Results Eighty participants were included in the analysis. The mean (SD) proportion of time spent in target range was 55.6% (23.6), this was lower in those with a reduced hypercapnic target range (88–92% or below) compared to those with a range of 92–96%; difference − 13.1% (95% CI − 3.0 to − 23.2), P  = 0.012. The proportion of time spent above range was 16.2% (22.9); this was higher in those with a reduced hypercapnic range; difference 21.6% (31.4 to 12), P  \\textless 0.001. The proportion of time below range was 28.4% (25.2); there was no difference between target ranges. The proportion of time spent in range was higher for those in a high dependency area in the multivariate model; difference 15.5% (95% CI 2.3 to 28.7), P  = 0.02. Conclusions Medical patients receiving oxygen in a ward setting spend significant periods of time with SpO 2 both above and below the prescribed target range while receiving oxygen therapy.\n
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\n \n\n \n \n \n \n \n \n Automatic versus manual oxygen titration using a novel nasal high-flow device in medical inpatients with an acute illness: a randomised controlled trial.\n \n \n \n \n\n\n \n Harper, J.; Kearns, N.; Bird, G.; Braithwaite, I.; Eathorne, A.; Shortt, N.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n BMJ Open Respiratory Research, 8(1): e000843. August 2021.\n \n\n\n\n
\n\n\n\n \n \n \"AutomaticPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n  \n \n 1 download\n \n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{harper_automatic_2021,\n\ttitle = {Automatic versus manual oxygen titration using a novel nasal high-flow device in medical inpatients with an acute illness: a randomised controlled trial},\n\tvolume = {8},\n\tissn = {2052-4439},\n\tshorttitle = {Automatic versus manual oxygen titration using a novel nasal high-flow device in medical inpatients with an acute illness},\n\turl = {https://bmjopenrespres.bmj.com/lookup/doi/10.1136/bmjresp-2020-000843},\n\tdoi = {10.1136/bmjresp-2020-000843},\n\tabstract = {Background\n              \n                Guideline recommendations state oxygen should be administered to acutely unwell patients to achieve a target oxygen saturation (SpO\n                2\n                ) range. The current practice of manual oxygen titration frequently results in SpO\n                2\n                outside of a prescribed range. The aim of this study was to assess the efficacy of automatic oxygen titration using a closed-loop feedback system to achieve SpO\n                2\n                within a prescribed target range\n              \n            \n            \n              Methods\n              \n                An open-label randomised parallel group trial was undertaken comparing automatic oxygen titration using a novel nasal high-flow device to manual oxygen titration using nasal high flow. Medical inpatients requiring oxygen therapy in Wellington Regional Hospital, New Zealand with a prescribed target SpO\n                2\n                range of 88\\%–92\\% or 92\\%–96\\% were recruited and randomised equally between the interventions for a period of 24 hours. The primary outcome was the proportion of time spent with SpO\n                2\n                within the prescribed range.\n              \n            \n            \n              Results\n              \n                20 patients were included in the analysis. Automatic oxygen titration resulted in a median (IQR) 96.2\\% (95.2–97.8) of time within the target range compared with 71\\% (59.4–88.3) with manual titration; difference (95\\% CI) 24.2\\% (7.9\\% to 35\\%), p{\\textless}0.001. There was a reduction in the time spent with SpO\n                2\n                ≥2\\% above and ≥2\\% below range in the automatic titration group, although the point estimate for the differences were small; −1\\% (−8.2\\% to −0.04\\%), p=0.017 and −2.4\\% (−11.5\\% to 0.3\\%), p=0.05 respectively.\n              \n            \n            \n              Conclusions\n              \n                Nasal high-flow with automatic oxygen titration resulted in a greater proportion of time spent with SpO\n                2\n                in target range compared with manual titration.\n              \n            \n            \n              Trial registration\n              The trial was registered with the Australian and New Zealand Clinical Trials Registry (ACTRN12619000901101).},\n\tlanguage = {en},\n\tnumber = {1},\n\turldate = {2021-10-02},\n\tjournal = {BMJ Open Respiratory Research},\n\tauthor = {Harper, James and Kearns, Nethmi and Bird, Grace and Braithwaite, Irene and Eathorne, Allie and Shortt, Nicholas and Weatherall, Mark and Beasley, Richard},\n\tmonth = aug,\n\tyear = {2021},\n\tpages = {e000843},\n}\n\n
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\n Background Guideline recommendations state oxygen should be administered to acutely unwell patients to achieve a target oxygen saturation (SpO 2 ) range. The current practice of manual oxygen titration frequently results in SpO 2 outside of a prescribed range. The aim of this study was to assess the efficacy of automatic oxygen titration using a closed-loop feedback system to achieve SpO 2 within a prescribed target range Methods An open-label randomised parallel group trial was undertaken comparing automatic oxygen titration using a novel nasal high-flow device to manual oxygen titration using nasal high flow. Medical inpatients requiring oxygen therapy in Wellington Regional Hospital, New Zealand with a prescribed target SpO 2 range of 88%–92% or 92%–96% were recruited and randomised equally between the interventions for a period of 24 hours. The primary outcome was the proportion of time spent with SpO 2 within the prescribed range. Results 20 patients were included in the analysis. Automatic oxygen titration resulted in a median (IQR) 96.2% (95.2–97.8) of time within the target range compared with 71% (59.4–88.3) with manual titration; difference (95% CI) 24.2% (7.9% to 35%), p\\textless0.001. There was a reduction in the time spent with SpO 2 ≥2% above and ≥2% below range in the automatic titration group, although the point estimate for the differences were small; −1% (−8.2% to −0.04%), p=0.017 and −2.4% (−11.5% to 0.3%), p=0.05 respectively. Conclusions Nasal high-flow with automatic oxygen titration resulted in a greater proportion of time spent with SpO 2 in target range compared with manual titration. Trial registration The trial was registered with the Australian and New Zealand Clinical Trials Registry (ACTRN12619000901101).\n
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\n \n\n \n \n \n \n \n \n Closed-Loop Oxygen Control Using a Novel Nasal High-Flow Device: A Randomized Crossover Trial.\n \n \n \n \n\n\n \n Harper, J. C.; Kearns, N. A; Maijers, I.; Bird, G. E; Braithwaite, I.; Shortt, N. P; Eathorne, A.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Respiratory Care, 66(3): 416–424. March 2021.\n \n\n\n\n
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@article{harper_closed-loop_2021,\n\ttitle = {Closed-{Loop} {Oxygen} {Control} {Using} a {Novel} {Nasal} {High}-{Flow} {Device}: {A} {Randomized} {Crossover} {Trial}},\n\tvolume = {66},\n\tissn = {0020-1324, 1943-3654},\n\tshorttitle = {Closed-{Loop} {Oxygen} {Control} {Using} a {Novel} {Nasal} {High}-{Flow} {Device}},\n\turl = {http://rc.rcjournal.com/lookup/doi/10.4187/respcare.08087},\n\tdoi = {10.4187/respcare.08087},\n\tlanguage = {en},\n\tnumber = {3},\n\turldate = {2021-04-28},\n\tjournal = {Respiratory Care},\n\tauthor = {Harper, James CP and Kearns, Nethmi A and Maijers, Ingrid and Bird, Grace E and Braithwaite, Irene and Shortt, Nicholas P and Eathorne, Allie and Weatherall, Mark and Beasley, Richard},\n\tmonth = mar,\n\tyear = {2021},\n\tpages = {416--424},\n}\n\n
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\n \n\n \n \n \n \n \n \n Audit of oxygen administration to achieve a target oxygen saturation range in acutely unwell medical patients.\n \n \n \n \n\n\n \n Harper, J.; Kearns, N.; Bird, G.; McLachlan, R.; Eathorne, A.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Postgraduate Medical Journal,postgradmedj–2020–139511. February 2021.\n \n\n\n\n
\n\n\n\n \n \n \"AuditPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n  \n \n 2 downloads\n \n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{harper_audit_2021-1,\n\ttitle = {Audit of oxygen administration to achieve a target oxygen saturation range in acutely unwell medical patients},\n\tissn = {0032-5473, 1469-0756},\n\turl = {https://pmj.bmj.com/lookup/doi/10.1136/postgradmedj-2020-139511},\n\tdoi = {10.1136/postgradmedj-2020-139511},\n\tabstract = {Purpose of the study\n              \n                To evaluate documentation of a target oxygen saturation (SpO\n                2\n                ) range and ability to achieve this range in acutely unwell inpatients.\n              \n            \n            \n              Study design\n              \n                In this single-centre audit, patients with discharge diagnoses of pneumonia, heart failure and exacerbation of asthma or COPD admitted to Wellington Regional Hospital, New Zealand between 1 June 2019 and 31 August 2019 who received oxygen were identified. In those with a documented target SpO\n                2\n                range, the proportion of SpO\n                2\n                measurements in the observation chart which were within, above and below range were determined as well as the maximum and minimum SpO\n                2\n                . Regression analysis was performed to determine whether these outcomes were influenced by the prescribed range, high-dependency care or the number of adjustments to oxygen administration.\n              \n            \n            \n              Results\n              \n                268 admissions were screened. Of the 100 eligible admissions who received oxygen, a target SpO\n                2\n                range was documented in 62. The mean (SD) proportion of SpO\n                2\n                measurements within range was 56.2 (30.6)\\%. A hypercapnic target SpO\n                2\n                range was associated with a higher probability of an SpO\n                2\n                above range; multivariate OR 5.34 (95\\% CI 1.65 to 17.3, p=0.006) and a lower probability of an SpO\n                2\n                below range; multivariate OR 0.25 (95\\% CI 0.08 to 0.80) p=0.02. The mean (SD) maximum SpO\n                2\n                was similar in those with a target range of 92\\%–96\\% versus a hypercapnic range; 96.2 (3.0)\\% and 95.2 (3.4)\\%, respectively.\n              \n            \n            \n              Conclusions\n              \n                Oxygen prescription and delivery in this clinical setting was suboptimal. SpO\n                2\n                values above the designated range are common, particularly in patients with a hypercapnic target range.},\n\tlanguage = {en},\n\turldate = {2021-04-28},\n\tjournal = {Postgraduate Medical Journal},\n\tauthor = {Harper, James and Kearns, Nethmi and Bird, Grace and McLachlan, Robert and Eathorne, Allie and Weatherall, Mark and Beasley, Richard},\n\tmonth = feb,\n\tyear = {2021},\n\tpages = {postgradmedj--2020--139511},\n}\n\n
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\n Purpose of the study To evaluate documentation of a target oxygen saturation (SpO 2 ) range and ability to achieve this range in acutely unwell inpatients. Study design In this single-centre audit, patients with discharge diagnoses of pneumonia, heart failure and exacerbation of asthma or COPD admitted to Wellington Regional Hospital, New Zealand between 1 June 2019 and 31 August 2019 who received oxygen were identified. In those with a documented target SpO 2 range, the proportion of SpO 2 measurements in the observation chart which were within, above and below range were determined as well as the maximum and minimum SpO 2 . Regression analysis was performed to determine whether these outcomes were influenced by the prescribed range, high-dependency care or the number of adjustments to oxygen administration. Results 268 admissions were screened. Of the 100 eligible admissions who received oxygen, a target SpO 2 range was documented in 62. The mean (SD) proportion of SpO 2 measurements within range was 56.2 (30.6)%. A hypercapnic target SpO 2 range was associated with a higher probability of an SpO 2 above range; multivariate OR 5.34 (95% CI 1.65 to 17.3, p=0.006) and a lower probability of an SpO 2 below range; multivariate OR 0.25 (95% CI 0.08 to 0.80) p=0.02. The mean (SD) maximum SpO 2 was similar in those with a target range of 92%–96% versus a hypercapnic range; 96.2 (3.0)% and 95.2 (3.4)%, respectively. Conclusions Oxygen prescription and delivery in this clinical setting was suboptimal. SpO 2 values above the designated range are common, particularly in patients with a hypercapnic target range.\n
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\n \n\n \n \n \n \n \n \n Is less really more for oxygen therapy in patients with acute respiratory failure?.\n \n \n \n \n\n\n \n Young, P. J.; Gladwin, B.; and Capdevila, M.\n\n\n \n\n\n\n Anaesthesia Critical Care & Pain Medicine, 40(2): 100858. April 2021.\n \n\n\n\n
\n\n\n\n \n \n \"IsPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{young_is_2021,\n\ttitle = {Is less really more for oxygen therapy in patients with acute respiratory failure?},\n\tvolume = {40},\n\tissn = {23525568},\n\turl = {https://linkinghub.elsevier.com/retrieve/pii/S2352556821000618},\n\tdoi = {10.1016/j.accpm.2021.100858},\n\tlanguage = {en},\n\tnumber = {2},\n\turldate = {2021-04-28},\n\tjournal = {Anaesthesia Critical Care \\& Pain Medicine},\n\tauthor = {Young, Paul J. and Gladwin, Benjamin and Capdevila, Mathieu},\n\tmonth = apr,\n\tyear = {2021},\n\tpages = {100858},\n}\n\n
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\n \n\n \n \n \n \n \n Effect of Oxygen Therapy on Mortality in the ICU.\n \n \n \n\n\n \n Young, P. J.\n\n\n \n\n\n\n The New England Journal of Medicine, 384(14): 1361–1363. April 2021.\n \n\n\n\n
\n\n\n\n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
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@article{young_effect_2021,\n\ttitle = {Effect of {Oxygen} {Therapy} on {Mortality} in the {ICU}},\n\tvolume = {384},\n\tissn = {1533-4406},\n\tdoi = {10.1056/NEJMe2101538},\n\tlanguage = {eng},\n\tnumber = {14},\n\tjournal = {The New England Journal of Medicine},\n\tauthor = {Young, Paul J.},\n\tmonth = apr,\n\tyear = {2021},\n\tpmid = {33826824},\n\tkeywords = {Humans, Intensive Care Units, Oxygen, Oxygen Inhalation Therapy, Respiratory Insufficiency},\n\tpages = {1361--1363},\n}\n\n
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\n \n\n \n \n \n \n \n \n Searching for the optimal oxygen saturation range in acutely unwell patients.\n \n \n \n \n\n\n \n Pilcher, J. M.; Kearns, C.; and Beasley, R.\n\n\n \n\n\n\n Emergency Medicine Journal, 38(3): 168–169. March 2021.\n \n\n\n\n
\n\n\n\n \n \n \"SearchingPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n  \n \n 5 downloads\n \n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{pilcher_searching_2021,\n\ttitle = {Searching for the optimal oxygen saturation range in acutely unwell patients},\n\tvolume = {38},\n\tissn = {1472-0205, 1472-0213},\n\turl = {https://emj.bmj.com/lookup/doi/10.1136/emermed-2020-210749},\n\tdoi = {10.1136/emermed-2020-210749},\n\tlanguage = {en},\n\tnumber = {3},\n\turldate = {2021-02-24},\n\tjournal = {Emergency Medicine Journal},\n\tauthor = {Pilcher, Janine Marie and Kearns, Ciléin and Beasley, Richard},\n\tmonth = mar,\n\tyear = {2021},\n\tpages = {168--169},\n}\n\n
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\n  \n 2020\n \n \n (5)\n \n \n
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\n \n\n \n \n \n \n \n \n Where to from here with recommendations for perioperative oxygen therapy?.\n \n \n \n \n\n\n \n Frei, D.; and Young, P. J.\n\n\n \n\n\n\n Anaesthesia Critical Care & Pain Medicine, 39(6): 755–757. December 2020.\n \n\n\n\n
\n\n\n\n \n \n \"WherePaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n  \n \n 1 download\n \n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{frei_where_2020,\n\ttitle = {Where to from here with recommendations for perioperative oxygen therapy?},\n\tvolume = {39},\n\tissn = {23525568},\n\turl = {https://linkinghub.elsevier.com/retrieve/pii/S2352556820302381},\n\tdoi = {10.1016/j.accpm.2020.07.022},\n\tlanguage = {en},\n\tnumber = {6},\n\turldate = {2021-05-12},\n\tjournal = {Anaesthesia Critical Care \\& Pain Medicine},\n\tauthor = {Frei, Daniel and Young, Paul J.},\n\tmonth = dec,\n\tyear = {2020},\n\tpages = {755--757},\n}\n\n
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\n \n\n \n \n \n \n \n \n The effect of conservative oxygen therapy on systemic biomarkers of oxidative stress in critically ill patients.\n \n \n \n \n\n\n \n Carr, A. C.; Spencer, E.; Mackle, D.; Hunt, A.; Judd, H.; Mehrtens, J.; Parker, K.; Stockwell, Z.; Gale, C.; Beaumont, M.; Kaur, S.; Bihari, S.; and Young, P. J.\n\n\n \n\n\n\n Free Radical Biology and Medicine, 160: 13–18. November 2020.\n \n\n\n\n
\n\n\n\n \n \n \"ThePaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{carr_effect_2020,\n\ttitle = {The effect of conservative oxygen therapy on systemic biomarkers of oxidative stress in critically ill patients},\n\tvolume = {160},\n\tissn = {08915849},\n\turl = {https://linkinghub.elsevier.com/retrieve/pii/S0891584920311151},\n\tdoi = {10.1016/j.freeradbiomed.2020.06.018},\n\tlanguage = {en},\n\turldate = {2021-05-07},\n\tjournal = {Free Radical Biology and Medicine},\n\tauthor = {Carr, Anitra C. and Spencer, Emma and Mackle, Diane and Hunt, Anna and Judd, Harriet and Mehrtens, Jan and Parker, Kim and Stockwell, Zoe and Gale, Caitlin and Beaumont, Megan and Kaur, Simran and Bihari, Shailesh and Young, Paul J.},\n\tmonth = nov,\n\tyear = {2020},\n\tpages = {13--18},\n}\n\n
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\n \n\n \n \n \n \n \n \n Closed-Loop Oxygen Control Using a Novel Nasal High-Flow Device: A Randomized Crossover Trial.\n \n \n \n \n\n\n \n Harper, J. C.; Kearns, N. A; Maijers, I.; Bird, G. E; Braithwaite, I.; Shortt, N. P; Eathorne, A.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Respiratory Care,respcare.08087. October 2020.\n \n\n\n\n
\n\n\n\n \n \n \"Closed-LoopPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{harper_closed-loop_2020,\n\ttitle = {Closed-{Loop} {Oxygen} {Control} {Using} a {Novel} {Nasal} {High}-{Flow} {Device}: {A} {Randomized} {Crossover} {Trial}},\n\tissn = {0020-1324, 1943-3654},\n\tshorttitle = {Closed-{Loop} {Oxygen} {Control} {Using} a {Novel} {Nasal} {High}-{Flow} {Device}},\n\turl = {http://rc.rcjournal.com/lookup/doi/10.4187/respcare.08087},\n\tdoi = {10.4187/respcare.08087},\n\tlanguage = {en},\n\turldate = {2020-12-02},\n\tjournal = {Respiratory Care},\n\tauthor = {Harper, James CP and Kearns, Nethmi A and Maijers, Ingrid and Bird, Grace E and Braithwaite, Irene and Shortt, Nicholas P and Eathorne, Allie and Weatherall, Mark and Beasley, Richard},\n\tmonth = oct,\n\tyear = {2020},\n\tpages = {respcare.08087},\n}\n\n
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\n \n\n \n \n \n \n \n \n Searching for the optimal oxygen saturation range in acutely unwell patients.\n \n \n \n \n\n\n \n Pilcher, J. M.; Kearns, C.; and Beasley, R.\n\n\n \n\n\n\n Emergency Medicine Journal,emermed–2020–210749. November 2020.\n \n\n\n\n
\n\n\n\n \n \n \"SearchingPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n  \n \n 1 download\n \n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{pilcher_searching_2020,\n\ttitle = {Searching for the optimal oxygen saturation range in acutely unwell patients},\n\tissn = {1472-0205, 1472-0213},\n\turl = {https://emj.bmj.com/lookup/doi/10.1136/emermed-2020-210749},\n\tdoi = {10.1136/emermed-2020-210749},\n\tlanguage = {en},\n\turldate = {2020-11-27},\n\tjournal = {Emergency Medicine Journal},\n\tauthor = {Pilcher, Janine Marie and Kearns, Ciléin and Beasley, Richard},\n\tmonth = nov,\n\tyear = {2020},\n\tpages = {emermed--2020--210749},\n}\n\n
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\n \n\n \n \n \n \n \n \n Conservative Oxygen Therapy during Mechanical Ventilation in the ICU.\n \n \n \n \n\n\n \n The ICU-ROX Investigators; Australian, t.; and Group, N. Z. I. C. S. C. T.\n\n\n \n\n\n\n New England Journal of Medicine, 382(11): 989–998. March 2020.\n Number: 11\n\n\n\n
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@article{the_icu-rox_investigators_and_the_australian_and_new_zealand_intensive_care_society_clinical_trials_group_conservative_2020,\n\ttitle = {Conservative {Oxygen} {Therapy} during {Mechanical} {Ventilation} in the {ICU}},\n\tvolume = {382},\n\tissn = {0028-4793, 1533-4406},\n\turl = {http://www.nejm.org/doi/10.1056/NEJMoa1903297},\n\tdoi = {10.1056/NEJMoa1903297},\n\tlanguage = {en},\n\tnumber = {11},\n\turldate = {2020-08-23},\n\tjournal = {New England Journal of Medicine},\n\tauthor = {{The ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group}},\n\tmonth = mar,\n\tyear = {2020},\n\tnote = {Number: 11},\n\tpages = {989--998},\n}\n\n
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\n  \n 2019\n \n \n (8)\n \n \n
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\n \n\n \n \n \n \n \n O2, do we know what to do?.\n \n \n \n\n\n \n Young, P. J.; Bagshaw, S. M.; Bailey, M.; Bellomo, R.; Mackle, D.; Pilcher, D.; Landoni, G.; Nichol, A.; and Martin, D.\n\n\n \n\n\n\n Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine, 21(4): 230–232. December 2019.\n Number: 4\n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n \n \n \n \n\n\n\n
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@article{young_o2_2019,\n\ttitle = {O2, do we know what to do?},\n\tvolume = {21},\n\tissn = {1441-2772},\n\tlanguage = {eng},\n\tnumber = {4},\n\tjournal = {Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine},\n\tauthor = {Young, Paul J. and Bagshaw, Sean M. and Bailey, Michael and Bellomo, Rinaldo and Mackle, Diane and Pilcher, David and Landoni, Giovanni and Nichol, Alistair and Martin, Daniel},\n\tmonth = dec,\n\tyear = {2019},\n\tpmid = {31778627},\n\tnote = {Number: 4},\n\tkeywords = {Humans, Oxygen},\n\tpages = {230--232},\n}\n\n
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\n \n\n \n \n \n \n \n \n Accuracy and precision of transcutaneous carbon dioxide monitoring: a systematic review and meta-analysis.\n \n \n \n \n\n\n \n Conway, A.; Tipton, E.; Liu, W.; Conway, Z.; Soalheira, K.; Sutherland, J.; and Fingleton, J.\n\n\n \n\n\n\n Thorax, 74(2): 157–163. February 2019.\n Number: 2\n\n\n\n
\n\n\n\n \n \n \"AccuracyPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{conway_accuracy_2019,\n\ttitle = {Accuracy and precision of transcutaneous carbon dioxide monitoring: a systematic review and meta-analysis},\n\tvolume = {74},\n\tissn = {0040-6376, 1468-3296},\n\tshorttitle = {Accuracy and precision of transcutaneous carbon dioxide monitoring},\n\turl = {http://thorax.bmj.com/lookup/doi/10.1136/thoraxjnl-2017-211466},\n\tdoi = {10.1136/thoraxjnl-2017-211466},\n\tabstract = {Background\n              \n                Transcutaneous carbon dioxide (TcCO\n                2\n                ) monitoring is a non-invasive alternative to arterial blood sampling. The aim of this review was to determine the accuracy and precision of TcCO\n                2\n                measurements.\n              \n            \n            \n              Methods\n              \n                Medline and EMBASE (2000–2016) were searched for studies that reported on a measurement of PaCO\n                2\n                that coincided with a measurement of TcCO\n                2\n                . Study selection and quality assessment (using the revised Quality Assessment of Diagnostic Accuracy Studies tool (QUADAS-2)) were performed independently. The Grading Quality of Evidence and Strength of Recommendation approach was used to summarise the strength of the body of evidence. Pooled estimates of the mean bias between TcCO\n                2\n                and PaCO\n                2\n                and limits of agreement with outer 95\\% CIs (termed population limits of agreement) were calculated.\n              \n            \n            \n              Results\n              \n                The mean bias was −0.1 mm Hg and the population limits of agreement were −15 to 15 mm Hg for 7021 paired measurements taken from 2817 participants in 73 studies, which was outside of the clinically acceptable range (7.5 mm Hg). The lowest PaCO\n                2\n                reported in the studies was 18 mm Hg and the highest was 103 mm Hg. The major sources of inconsistency were sensor location and temperature. The population limits of agreement were within the clinically acceptable range across 3974 paired measurements from 1786 participants in 44 studies that applied the sensor to the earlobe using the TOSCA and Sentec devices (−6 to 6 mm Hg).\n              \n            \n            \n              Conclusion\n              \n                There are substantial differences between TcCO\n                2\n                and PaCO\n                2\n                depending on the context in which this technology is used. TcCO\n                2\n                sensors should preferentially be applied to the earlobe and users should consider setting the temperature of the sensor higher than 42°C when monitoring at other sites.\n              \n            \n            \n              Systematic review registration number\n              PROSPERO; CRD42017057450.},\n\tlanguage = {en},\n\tnumber = {2},\n\turldate = {2020-08-23},\n\tjournal = {Thorax},\n\tauthor = {Conway, Aaron and Tipton, Elizabeth and Liu, Wei-Hong and Conway, Zachary and Soalheira, Kathleen and Sutherland, Joanna and Fingleton, James},\n\tmonth = feb,\n\tyear = {2019},\n\tnote = {Number: 2},\n\tpages = {157--163},\n}\n\n
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\n Background Transcutaneous carbon dioxide (TcCO 2 ) monitoring is a non-invasive alternative to arterial blood sampling. The aim of this review was to determine the accuracy and precision of TcCO 2 measurements. Methods Medline and EMBASE (2000–2016) were searched for studies that reported on a measurement of PaCO 2 that coincided with a measurement of TcCO 2 . Study selection and quality assessment (using the revised Quality Assessment of Diagnostic Accuracy Studies tool (QUADAS-2)) were performed independently. The Grading Quality of Evidence and Strength of Recommendation approach was used to summarise the strength of the body of evidence. Pooled estimates of the mean bias between TcCO 2 and PaCO 2 and limits of agreement with outer 95% CIs (termed population limits of agreement) were calculated. Results The mean bias was −0.1 mm Hg and the population limits of agreement were −15 to 15 mm Hg for 7021 paired measurements taken from 2817 participants in 73 studies, which was outside of the clinically acceptable range (7.5 mm Hg). The lowest PaCO 2 reported in the studies was 18 mm Hg and the highest was 103 mm Hg. The major sources of inconsistency were sensor location and temperature. The population limits of agreement were within the clinically acceptable range across 3974 paired measurements from 1786 participants in 44 studies that applied the sensor to the earlobe using the TOSCA and Sentec devices (−6 to 6 mm Hg). Conclusion There are substantial differences between TcCO 2 and PaCO 2 depending on the context in which this technology is used. TcCO 2 sensors should preferentially be applied to the earlobe and users should consider setting the temperature of the sensor higher than 42°C when monitoring at other sites. Systematic review registration number PROSPERO; CRD42017057450.\n
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\n \n\n \n \n \n \n \n \n Sequence analysis of capnography waveform abnormalities during nurse-administered procedural sedation and analgesia in the cardiac catheterization laboratory.\n \n \n \n \n\n\n \n Conway, A.; Collins, P.; Chang, K.; Mafeld, S.; Sutherland, J.; and Fingleton, J.\n\n\n \n\n\n\n Scientific Reports, 9(1): 10214. December 2019.\n Number: 1\n\n\n\n
\n\n\n\n \n \n \"SequencePaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{conway_sequence_2019,\n\ttitle = {Sequence analysis of capnography waveform abnormalities during nurse-administered procedural sedation and analgesia in the cardiac catheterization laboratory},\n\tvolume = {9},\n\tissn = {2045-2322},\n\turl = {http://www.nature.com/articles/s41598-019-46751-2},\n\tdoi = {10.1038/s41598-019-46751-2},\n\tlanguage = {en},\n\tnumber = {1},\n\turldate = {2020-08-23},\n\tjournal = {Scientific Reports},\n\tauthor = {Conway, Aaron and Collins, Peter and Chang, Kristina and Mafeld, Sebastian and Sutherland, Joanna and Fingleton, James},\n\tmonth = dec,\n\tyear = {2019},\n\tnote = {Number: 1},\n\tpages = {10214},\n}\n\n
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\n \n\n \n \n \n \n \n \n Practice patterns and perceptions of Australian and New Zealand anaesthetists towards perioperative oxygen therapy.\n \n \n \n \n\n\n \n Frei, D. R; Beasley, R.; Campbell, D.; Leslie, K.; Merry, A. F; Moore, M.; Myles, P. S; Ruawai-Hamilton, L.; Short, T. G; and Young, P. J\n\n\n \n\n\n\n Anaesthesia and Intensive Care, 47(3): 288–294. May 2019.\n Number: 3\n\n\n\n
\n\n\n\n \n \n \"PracticePaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n  \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{frei_practice_2019,\n\ttitle = {Practice patterns and perceptions of {Australian} and {New} {Zealand} anaesthetists towards perioperative oxygen therapy},\n\tvolume = {47},\n\tissn = {0310-057X, 1448-0271},\n\turl = {http://journals.sagepub.com/doi/10.1177/0310057X19842245},\n\tdoi = {10.1177/0310057X19842245},\n\tabstract = {We conducted a survey of Australian and New Zealand anaesthetists to determine self-reported practice of perioperative oxygen administration and to quantify perceptions regarding the perceived benefits and risks resulting from liberal oxygen therapy delivered in a manner consistent with the current World Health Organization guidelines. In addition, we sought feedback on the acceptability of several proposed clinical trial designs aiming to assess the overall effect of liberal and restricted perioperative oxygen regimens on patient outcomes. We developed a 23-question electronic survey that was emailed to 972 randomly selected Australian and New Zealand College of Anaesthetists (ANZCA) Fellows. We received responses from 282 of 972 invitees (response rate 29\\%). The majority of survey participants indicated that they routinely titrate inspired oxygen to a level they feel is safe (164/282, 58\\%) or minimise oxygen administration (82/282, 29\\%), while 5\\% of respondents indicated that they aim to maximise oxygen administration. The mean value for targeted intraoperative fraction inspired oxygen (FiO\n              2\n              ) was 0.41 (standard deviation 0.12). Of the survey respondents, 2/282 (0.7\\%) indicated they believe that routine intra- and postoperative administration of ≥80\\% oxygen reduces the risk of surgical site infection. Well-designed and conducted randomised trials on this topic may help to better direct clinicians' choices. A high level of willingness to participate (80\\% of responses) in a study designed to investigate the impact of differing approaches to perioperative oxygen administration suggests that recruitment is likely to be feasible in a future study.},\n\tlanguage = {en},\n\tnumber = {3},\n\turldate = {2020-08-23},\n\tjournal = {Anaesthesia and Intensive Care},\n\tauthor = {Frei, Daniel R and Beasley, Richard and Campbell, Douglas and Leslie, Kate and Merry, Alan F and Moore, Matthew and Myles, Paul S and Ruawai-Hamilton, Laura and Short, Tim G and Young, Paul J},\n\tmonth = may,\n\tyear = {2019},\n\tnote = {Number: 3},\n\tpages = {288--294},\n}\n\n
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\n We conducted a survey of Australian and New Zealand anaesthetists to determine self-reported practice of perioperative oxygen administration and to quantify perceptions regarding the perceived benefits and risks resulting from liberal oxygen therapy delivered in a manner consistent with the current World Health Organization guidelines. In addition, we sought feedback on the acceptability of several proposed clinical trial designs aiming to assess the overall effect of liberal and restricted perioperative oxygen regimens on patient outcomes. We developed a 23-question electronic survey that was emailed to 972 randomly selected Australian and New Zealand College of Anaesthetists (ANZCA) Fellows. We received responses from 282 of 972 invitees (response rate 29%). The majority of survey participants indicated that they routinely titrate inspired oxygen to a level they feel is safe (164/282, 58%) or minimise oxygen administration (82/282, 29%), while 5% of respondents indicated that they aim to maximise oxygen administration. The mean value for targeted intraoperative fraction inspired oxygen (FiO 2 ) was 0.41 (standard deviation 0.12). Of the survey respondents, 2/282 (0.7%) indicated they believe that routine intra- and postoperative administration of ≥80% oxygen reduces the risk of surgical site infection. Well-designed and conducted randomised trials on this topic may help to better direct clinicians' choices. A high level of willingness to participate (80% of responses) in a study designed to investigate the impact of differing approaches to perioperative oxygen administration suggests that recruitment is likely to be feasible in a future study.\n
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\n \n\n \n \n \n \n \n \n Pre-apneic capnography waveform abnormalities during procedural sedation and analgesia.\n \n \n \n \n\n\n \n Conway, A.; Collins, P.; Chang, K.; Mafeld, S.; Sutherland, J.; Fingleton, J.; and Parotto, M.\n\n\n \n\n\n\n Journal of Clinical Monitoring and Computing. September 2019.\n \n\n\n\n
\n\n\n\n \n \n \"Pre-apneicPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n  \n \n 1 download\n \n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{conway_pre-apneic_2019,\n\ttitle = {Pre-apneic capnography waveform abnormalities during procedural sedation and analgesia},\n\tissn = {1387-1307, 1573-2614},\n\turl = {http://link.springer.com/10.1007/s10877-019-00391-z},\n\tdoi = {10.1007/s10877-019-00391-z},\n\tlanguage = {en},\n\turldate = {2020-08-23},\n\tjournal = {Journal of Clinical Monitoring and Computing},\n\tauthor = {Conway, Aaron and Collins, Peter and Chang, Kristina and Mafeld, Sebastian and Sutherland, Joanna and Fingleton, James and Parotto, Matteo},\n\tmonth = sep,\n\tyear = {2019},\n}\n\n
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\n \n\n \n \n \n \n \n \n Increased risk of mortality with liberal oxygen therapy compared with conservative oxygen therapy in critically ill adults.\n \n \n \n \n\n\n \n Beasley, R.; and Mackle, D.\n\n\n \n\n\n\n BMJ Evidence-Based Medicine, 24(3): 113–114. June 2019.\n Number: 3\n\n\n\n
\n\n\n\n \n \n \"IncreasedPaper\n  \n \n\n \n \n doi\n  \n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{beasley_increased_2019,\n\ttitle = {Increased risk of mortality with liberal oxygen therapy compared with conservative oxygen therapy in critically ill adults},\n\tvolume = {24},\n\tissn = {2515-446X, 2515-4478},\n\turl = {http://ebm.bmj.com/lookup/doi/10.1136/bmjebm-2018-111054},\n\tdoi = {10.1136/bmjebm-2018-111054},\n\tlanguage = {en},\n\tnumber = {3},\n\turldate = {2020-08-23},\n\tjournal = {BMJ Evidence-Based Medicine},\n\tauthor = {Beasley, Richard and Mackle, Diane},\n\tmonth = jun,\n\tyear = {2019},\n\tnote = {Number: 3},\n\tpages = {113--114},\n}\n\n
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\n \n\n \n \n \n \n \n Practice patterns and perceptions of Australian and New Zealand anaesthetists towards perioperative oxygen therapy.\n \n \n \n\n\n \n R Frei, D.; Beasley, R.; Campbell, D.; Leslie, K.; Merry, A.; Moore, M.; S Myles, P.; Ruawai-Hamilton, L.; G Short, T.; and Young, P.\n\n\n \n\n\n\n Anaesthesia and Intensive Care,0310057X1984224. 2019.\n \n\n\n\n
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@article{r_frei_practice_2019,\n\ttitle = {Practice patterns and perceptions of {Australian} and {New} {Zealand} anaesthetists towards perioperative oxygen therapy},\n\tdoi = {10.1177/0310057X19842245},\n\tjournal = {Anaesthesia and Intensive Care},\n\tauthor = {R Frei, Daniel and Beasley, Richard and Campbell, Douglas and Leslie, Kate and Merry, Alan and Moore, Matthew and S Myles, Paul and Ruawai-Hamilton, Laura and G Short, Tim and Young, Paul},\n\tyear = {2019},\n\tpages = {0310057X1984224},\n}\n\n
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\n \n\n \n \n \n \n \n Oxygen: a new look at an old therapy.\n \n \n \n\n\n \n Beasley, R.; Mackle, D.; and Young, P.\n\n\n \n\n\n\n Journal of the Royal Society of New Zealand,1–17. 2019.\n \n\n\n\n
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@article{beasley_oxygen_2019,\n\ttitle = {Oxygen: a new look at an old therapy},\n\tdoi = {10.1080/03036758.2019.1566154},\n\tjournal = {Journal of the Royal Society of New Zealand},\n\tauthor = {Beasley, Richard and Mackle, Diane and Young, Paul},\n\tyear = {2019},\n\tpages = {1--17},\n}\n\n
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\n  \n 2018\n \n \n (6)\n \n \n
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\n \n\n \n \n \n \n \n Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX).\n \n \n \n\n\n \n Mackle, D. M; Bailey, M. J; Beasley, R. W; Bellomo, R.; Bennett, V.; Deane, A.; Eastwood, G. M; Finfer, S.; Freebairn, R.; and Litton, E.\n\n\n \n\n\n\n Critical Care and Resuscitation, 20(1): 22. 2018.\n Number: 1 Publisher: The Australasian Medical Publishing Company\n\n\n\n
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@article{mackle_protocol_2018,\n\ttitle = {Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy ({ICU}-{ROX})},\n\tvolume = {20},\n\tnumber = {1},\n\tjournal = {Critical Care and Resuscitation},\n\tauthor = {Mackle, Diane M and Bailey, Michael J and Beasley, Richard W and Bellomo, Rinaldo and Bennett, Victoria and Deane, Adam and Eastwood, Glenn M and Finfer, Simon and Freebairn, Ross and Litton, Edward},\n\tyear = {2018},\n\tnote = {Number: 1\nPublisher: The Australasian Medical Publishing Company},\n\tpages = {22},\n}\n\n
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\n \n\n \n \n \n \n \n Oxygen versus air-driven nebulisers for exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial.\n \n \n \n\n\n \n Bardsley, G.; Pilcher, J.; McKinstry, S.; Shirtcliffe, P.; Berry, J.; Fingleton, J.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n BMC Pulmonary Medicine, 18. 2018.\n \n\n\n\n
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@article{bardsley_oxygen_2018,\n\ttitle = {Oxygen versus air-driven nebulisers for exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial},\n\tvolume = {18},\n\tdoi = {10.1186/s12890-018-0720-7},\n\tjournal = {BMC Pulmonary Medicine},\n\tauthor = {Bardsley, George and Pilcher, Janine and McKinstry, Steven and Shirtcliffe, Philippa and Berry, James and Fingleton, James and Weatherall, Mark and Beasley, Richard},\n\tyear = {2018},\n}\n\n
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\n \n\n \n \n \n \n \n Oxygen therapy in acute resuscitation.\n \n \n \n\n\n \n Frei, D. R; and Young, P. J\n\n\n \n\n\n\n Current opinion in critical care, 24(6): 506–511. 2018.\n Number: 6 Publisher: LWW\n\n\n\n
\n\n\n\n \n\n \n\n \n link\n  \n \n\n bibtex\n \n\n \n\n \n\n \n \n \n \n \n \n \n\n  \n \n \n\n\n\n
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@article{frei_oxygen_2018,\n\ttitle = {Oxygen therapy in acute resuscitation},\n\tvolume = {24},\n\tissn = {1070-5295},\n\tnumber = {6},\n\tjournal = {Current opinion in critical care},\n\tauthor = {Frei, Daniel R and Young, Paul J},\n\tyear = {2018},\n\tnote = {Number: 6\nPublisher: LWW},\n\tpages = {506--511},\n}\n\n
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\n \n\n \n \n \n \n \n Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis.\n \n \n \n\n\n \n Chu, D. K; Kim, L. H Y; Young, P. J; Zamiri, N.; Almenawer, S. A; Jaeschke, R.; Szczeklik, W.; Schünemann, H. J; Neary, J. D; and Alhazzani, W.\n\n\n \n\n\n\n The Lancet, 391(10131): 1693–1705. 2018.\n Number: 10131 Publisher: Elsevier\n\n\n\n
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@article{chu_mortality_2018,\n\ttitle = {Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy ({IOTA}): a systematic review and meta-analysis},\n\tvolume = {391},\n\tissn = {0140-6736},\n\tnumber = {10131},\n\tjournal = {The Lancet},\n\tauthor = {Chu, Derek K and Kim, Lisa H Y and Young, Paul J and Zamiri, Nima and Almenawer, Saleh A and Jaeschke, Roman and Szczeklik, Wojciech and Schünemann, Holger J and Neary, John D and Alhazzani, Waleed},\n\tyear = {2018},\n\tnote = {Number: 10131\nPublisher: Elsevier},\n\tpages = {1693--1705},\n}\n\n
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\n \n\n \n \n \n \n \n Increased risk of mortality with liberal oxygen therapy compared with conservative oxygen therapy in critically ill adults.\n \n \n \n\n\n \n Beasley, R.; and Mackle, D.\n\n\n \n\n\n\n BMJ Evidence-Based Medicine,bmjebm–2018. 2018.\n \n\n\n\n
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@article{beasley_increased_2018,\n\ttitle = {Increased risk of mortality with liberal oxygen therapy compared with conservative oxygen therapy in critically ill adults},\n\tdoi = {10.1136/bmjebm-2018-111054},\n\tjournal = {BMJ Evidence-Based Medicine},\n\tauthor = {Beasley, Richard and Mackle, Diane},\n\tyear = {2018},\n\tpages = {bmjebm--2018},\n}\n\n
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\n \n\n \n \n \n \n \n A two centre observational study of simultaneous pulse oximetry and arterial oxygen saturation recordings in intensive care unit patients.\n \n \n \n\n\n \n Ebmeier, S J; Barker, M; Bacon, M; Beasley, R C; Bellomo, R.; Chong, C K.; Eastwood, G. M; Gilchrist, J; Kagaya, H; and Pilcher, J\n\n\n \n\n\n\n Anaesthesia and intensive care, 46(3): 297–303. 2018.\n Number: 3 Publisher: SAGE Publications Sage UK: London, England\n\n\n\n
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@article{ebmeier_two_2018,\n\ttitle = {A two centre observational study of simultaneous pulse oximetry and arterial oxygen saturation recordings in intensive care unit patients},\n\tvolume = {46},\n\tissn = {0310-057X},\n\tnumber = {3},\n\tjournal = {Anaesthesia and intensive care},\n\tauthor = {Ebmeier, S J and Barker, M and Bacon, M and Beasley, R C and Bellomo, Rinaldo and Chong, C Knee and Eastwood, Glenn M and Gilchrist, J and Kagaya, H and Pilcher, J},\n\tyear = {2018},\n\tnote = {Number: 3\nPublisher: SAGE Publications Sage UK: London, England},\n\tpages = {297--303},\n}\n\n
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\n  \n 2017\n \n \n (6)\n \n \n
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\n \n\n \n \n \n \n \n Target oxygen saturation range: 92–96% Versus 94–98%.\n \n \n \n\n\n \n Beasley, R.; Chien, J.; Douglas, J.; Eastlake, L.; Farah, C.; King, G.; Moore, R.; Pilcher, J.; Richards, M.; and Smith, S.\n\n\n \n\n\n\n Respirology, 22(1): 200–202. 2017.\n Number: 1 Publisher: Wiley Online Library\n\n\n\n
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@article{beasley_target_2017,\n\ttitle = {Target oxygen saturation range: 92–96\\% {Versus} 94–98\\%},\n\tvolume = {22},\n\tissn = {1323-7799},\n\tnumber = {1},\n\tjournal = {Respirology},\n\tauthor = {Beasley, Richard and Chien, Jimmy and Douglas, James and Eastlake, Leonie and Farah, Claude and King, Gregory and Moore, Rosemary and Pilcher, Janine and Richards, Michael and Smith, Sheree},\n\tyear = {2017},\n\tnote = {Number: 1\nPublisher: Wiley Online Library},\n\tpages = {200--202},\n}\n\n
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\n \n\n \n \n \n \n \n Physiological effects of titrated oxygen via nasal high-flow cannulae in COPD exacerbations: A randomized controlled cross-over trial.\n \n \n \n\n\n \n Pilcher, J.; Eastlake, L.; Richards, M.; Power, S.; Cripps, T.; Bibby, S.; Braithwaite, I.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Respirology (Carlton, Vic.), 22. 2017.\n \n\n\n\n
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@article{pilcher_physiological_2017,\n\ttitle = {Physiological effects of titrated oxygen via nasal high-flow cannulae in {COPD} exacerbations: {A} randomized controlled cross-over trial},\n\tvolume = {22},\n\tdoi = {10.1111/resp.13050},\n\tjournal = {Respirology (Carlton, Vic.)},\n\tauthor = {Pilcher, Janine and Eastlake, Leonie and Richards, Michael and Power, Sharon and Cripps, Terrianne and Bibby, Susan and Braithwaite, Irene and Weatherall, Mark and Beasley, Richard},\n\tyear = {2017},\n}\n\n
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\n \n\n \n \n \n \n \n Oxygen compared to air driven nebulisers for acute exacerbations of COPD: a randomised controlled trial.\n \n \n \n\n\n \n Bardsley, G.; McKinstry, S.; Pilcher, J.; Fingleton, J.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n In pages PA684, 2017. \n \n\n\n\n
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@inproceedings{bardsley_oxygen_2017,\n\ttitle = {Oxygen compared to air driven nebulisers for acute exacerbations of {COPD}: a randomised controlled trial},\n\tdoi = {10.1183/1393003.congress-2017.PA684},\n\tauthor = {Bardsley, George and McKinstry, Steve and Pilcher, Janine and Fingleton, James and Weatherall, Mark and Beasley, Richard},\n\tyear = {2017},\n\tpages = {PA684},\n}\n\n
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\n \n\n \n \n \n \n \n Intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX): results of the pilot phase.\n \n \n \n\n\n \n Young, P. J; Mackle, D. M; Bailey, M. J; Beasley, R. W; Bennett, V. L; Deane, A. M; Eastwood, G. M; Finfer, S.; Freebairn, R. C; and Litton, E.\n\n\n \n\n\n\n Critical care and resuscitation: journal of the Australasian Academy of Critical Care Medicine, 19(4): 344–354. 2017.\n Number: 4 Publisher: Australasian Medical Publishing Co. Ltd\n\n\n\n
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@article{young_intensive_2017,\n\ttitle = {Intensive care unit randomised trial comparing two approaches to oxygen therapy ({ICU}-{ROX}): results of the pilot phase},\n\tvolume = {19},\n\tissn = {1441-2772},\n\tnumber = {4},\n\tjournal = {Critical care and resuscitation: journal of the Australasian Academy of Critical Care Medicine},\n\tauthor = {Young, Paul J and Mackle, Diane M and Bailey, Michael J and Beasley, Richard W and Bennett, Victoria L and Deane, Adam M and Eastwood, Glenn M and Finfer, Simon and Freebairn, Ross C and Litton, Edward},\n\tyear = {2017},\n\tnote = {Number: 4\nPublisher: Australasian Medical Publishing Co. Ltd},\n\tpages = {344--354},\n}\n\n
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\n \n\n \n \n \n \n \n High flow or titrated oxygen for obese medical inpatients: A randomised crossover trial.\n \n \n \n\n\n \n Pilcher, J.; Richards, M.; Eastlake, L.; J McKinstry, S.; Bardsley, G.; Jefferies, S.; Braithwaite, I.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n The Medical Journal of Australia, 207: 430–434. 2017.\n \n\n\n\n
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@article{pilcher_high_2017,\n\ttitle = {High flow or titrated oxygen for obese medical inpatients: {A} randomised crossover trial},\n\tvolume = {207},\n\tdoi = {10.5694/mja17.00270},\n\tjournal = {The Medical Journal of Australia},\n\tauthor = {Pilcher, Janine and Richards, Michael and Eastlake, Leonie and J McKinstry, Steven and Bardsley, George and Jefferies, Sarah and Braithwaite, Irene and Weatherall, Mark and Beasley, Richard},\n\tyear = {2017},\n\tpages = {430--434},\n}\n\n
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\n \n\n \n \n \n \n \n BTS guideline for oxygen use in adults in healthcare and emergency settings.\n \n \n \n\n\n \n O'driscoll, B R; Howard, L S; Earis, J; and Mak, V\n\n\n \n\n\n\n Thorax, 72(Suppl 1): ii1–ii90. 2017.\n Number: Suppl 1 Publisher: BMJ Publishing Group Ltd\n\n\n\n
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@article{odriscoll_bts_2017,\n\ttitle = {{BTS} guideline for oxygen use in adults in healthcare and emergency settings},\n\tvolume = {72},\n\tissn = {0040-6376},\n\tnumber = {Suppl 1},\n\tjournal = {Thorax},\n\tauthor = {O'driscoll, B R and Howard, L S and Earis, J and Mak, V},\n\tyear = {2017},\n\tnote = {Number: Suppl 1\nPublisher: BMJ Publishing Group Ltd},\n\tpages = {ii1--ii90},\n}\n\n
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\n  \n 2016\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n Target oxygen saturation range: 92-96% Versus 94-98%.\n \n \n \n\n\n \n Chien, J.; King, G.; Farah, C.; Walters, H.; Moore, R.; Douglas, J.; Smith, S.; Pilcher, J.; Eastlake, L.; Beasley, R.; and Richards, M.\n\n\n \n\n\n\n Respirology, 22(1): 200–202. 2016.\n Number: 1\n\n\n\n
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@article{chien_target_2016,\n\ttitle = {Target oxygen saturation range: 92-96\\% {Versus} 94-98\\%},\n\tvolume = {22},\n\tdoi = {10.1111/resp.12879},\n\tnumber = {1},\n\tjournal = {Respirology},\n\tauthor = {Chien, Jimmy and King, Gregory and Farah, Claude and Walters, Haydn and Moore, Rosemary and Douglas, James and Smith, Sheree and Pilcher, Janine and Eastlake, Leonie and Beasley, Richard and Richards, Michael},\n\tyear = {2016},\n\tnote = {Number: 1},\n\tkeywords = {abbreviations, adult, apy, british thoracic society, bts, chronic, copd, fio 2, fraction of inspired, guideline, obstructive pulmonary disease, oxygen, oxygen inhalation ther-, target oxygen saturation range},\n\tpages = {200--202},\n}\n\n
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\n \n\n \n \n \n \n \n Conservative versus liberal oxygenation targets for mechanically ventilated patients. A pilot multicenter randomized controlled trial.\n \n \n \n\n\n \n Panwar, R.; Hardie, M.; Bellomo, R.; Barrot, L.; Eastwood, G. M; Young, P. J; Capellier, G.; Harrigan, P. W J; and Bailey, M.\n\n\n \n\n\n\n American journal of respiratory and critical care medicine, 193(1): 43–51. 2016.\n Number: 1 Publisher: American Thoracic Society\n\n\n\n
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@article{panwar_conservative_2016,\n\ttitle = {Conservative versus liberal oxygenation targets for mechanically ventilated patients. {A} pilot multicenter randomized controlled trial},\n\tvolume = {193},\n\tissn = {1073-449X},\n\tnumber = {1},\n\tjournal = {American journal of respiratory and critical care medicine},\n\tauthor = {Panwar, Rakshit and Hardie, Miranda and Bellomo, Rinaldo and Barrot, Loïc and Eastwood, Glenn M and Young, Paul J and Capellier, Gilles and Harrigan, Peter W J and Bailey, Michael},\n\tyear = {2016},\n\tnote = {Number: 1\nPublisher: American Thoracic Society},\n\tpages = {43--51},\n}\n\n
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\n  \n 2015\n \n \n (4)\n \n \n
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\n \n\n \n \n \n \n \n Thoracic Society of Australia and New Zealand oxygen guidelines for acute oxygen use in adults: ‘Swimming between the flags'.\n \n \n \n\n\n \n Beasley, R.; Chien, J.; Douglas, J.; Eastlake, L.; Farah, C.; King, G.; Moore, R.; Pilcher, J.; Richards, M.; Smith, S.; and Walters, H.\n\n\n \n\n\n\n Respirology, 20: 1182–1191. 2015.\n \n\n\n\n
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@article{beasley_thoracic_2015,\n\ttitle = {Thoracic {Society} of {Australia} and {New} {Zealand} oxygen guidelines for acute oxygen use in adults: ‘{Swimming} between the flags'},\n\tvolume = {20},\n\tdoi = {10.1111/resp.12620},\n\tjournal = {Respirology},\n\tauthor = {Beasley, Richard and Chien, Jimmy and Douglas, James and Eastlake, Leonie and Farah, Claude and King, Gregory and Moore, Rosemary and Pilcher, Janine and Richards, Michael and Smith, Sheree and Walters, Haydn},\n\tyear = {2015},\n\tpages = {1182--1191},\n}\n\n
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\n \n\n \n \n \n \n \n Oxygenation targets and monitoring in the critically ill: a point prevalence study of clinical practice in australia and New Zealand.\n \n \n \n\n\n \n Young, P. J; Beasley, R. W; Capellier, G.; Eastwood, G. M; and Webb, S. A R\n\n\n \n\n\n\n Critical Care and Resuscitation, 17(3): 202. 2015.\n Number: 3 Publisher: The Australasian Medical Publishing Company\n\n\n\n
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@article{young_oxygenation_2015,\n\ttitle = {Oxygenation targets and monitoring in the critically ill: a point prevalence study of clinical practice in australia and {New} {Zealand}},\n\tvolume = {17},\n\tnumber = {3},\n\tjournal = {Critical Care and Resuscitation},\n\tauthor = {Young, Paul J and Beasley, Richard W and Capellier, Gilles and Eastwood, Glenn M and Webb, Steve A R},\n\tyear = {2015},\n\tnote = {Number: 3\nPublisher: The Australasian Medical Publishing Company},\n\tpages = {202},\n}\n\n
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\n \n\n \n \n \n \n \n Oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease.\n \n \n \n\n\n \n Pilcher, J.; Weatherall, M.; Perrin, K.; and Beasley, R.\n\n\n \n\n\n\n Expert review of respiratory medicine, 9: 1–7. 2015.\n \n\n\n\n
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@article{pilcher_oxygen_2015,\n\ttitle = {Oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease},\n\tvolume = {9},\n\tdoi = {10.1586/17476348.2015.1016503},\n\tjournal = {Expert review of respiratory medicine},\n\tauthor = {Pilcher, Janine and Weatherall, Mark and Perrin, Kyle and Beasley, Richard},\n\tyear = {2015},\n\tpages = {1--7},\n}\n\n
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\n \n\n \n \n \n \n \n Acute use of oxygen therapy.\n \n \n \n\n\n \n Pilcher, J.; and Beasley, R.\n\n\n \n\n\n\n Australian prescriber, 38(3): 98. 2015.\n Number: 3 Publisher: Citeseer\n\n\n\n
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@article{pilcher_acute_2015,\n\ttitle = {Acute use of oxygen therapy},\n\tvolume = {38},\n\tnumber = {3},\n\tjournal = {Australian prescriber},\n\tauthor = {Pilcher, Janine and Beasley, Richard},\n\tyear = {2015},\n\tnote = {Number: 3\nPublisher: Citeseer},\n\tpages = {98},\n}\n\n
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\n  \n 2013\n \n \n (2)\n \n \n
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\n \n\n \n \n \n \n \n The effect of high concentration oxygen therapy on PaCO2 in acute and chronic respiratory disorders.\n \n \n \n\n\n \n Pilcher, J.; Perrin, K.; and Beasley, R.\n\n\n \n\n\n\n Translational Respiratory Medicine, 1. 2013.\n \n\n\n\n
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@article{pilcher_effect_2013,\n\ttitle = {The effect of high concentration oxygen therapy on {PaCO2} in acute and chronic respiratory disorders},\n\tvolume = {1},\n\tdoi = {10.1186/2213-0802-1-8},\n\tjournal = {Translational Respiratory Medicine},\n\tauthor = {Pilcher, Janine and Perrin, Kyle and Beasley, Richard},\n\tyear = {2013},\n}\n\n
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\n \n\n \n \n \n \n \n Comparative audit of oxygen use in the prehospital setting in acute COPD exacerbation over 5 years.\n \n \n \n\n\n \n Pilcher, J.; Cameron, L.; Braithwaite, I.; Bowles, D.; Swain, A.; Bailey, M.; Weatherall, M.; Beasley, R.; and Perrin, K.\n\n\n \n\n\n\n Emergency medicine journal : EMJ, 32. 2013.\n \n\n\n\n
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@article{pilcher_comparative_2013,\n\ttitle = {Comparative audit of oxygen use in the prehospital setting in acute {COPD} exacerbation over 5 years},\n\tvolume = {32},\n\tdoi = {10.1136/emermed-2013-203094},\n\tjournal = {Emergency medicine journal : EMJ},\n\tauthor = {Pilcher, Janine and Cameron, Laird and Braithwaite, Irene and Bowles, Darren and Swain, Andrew and Bailey, Mark and Weatherall, Mark and Beasley, Richard and Perrin, Kyle},\n\tyear = {2013},\n}\n\n
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\n  \n 2012\n \n \n (4)\n \n \n
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\n \n\n \n \n \n \n \n The association between early arterial oxygenation and mortality in ventilated patients with acute ischaemic stroke.\n \n \n \n\n\n \n Young, P.; Beasley, R.; Bailey, M.; Bellomo, R.; Eastwood, G.; Nichol, A.; Pilcher, D.; Yunos, N.; Egi, M.; Hart, G.; Reade, M.; and James Cooper, D\n\n\n \n\n\n\n Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 14: 14–19. 2012.\n \n\n\n\n
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@article{young_association_2012,\n\ttitle = {The association between early arterial oxygenation and mortality in ventilated patients with acute ischaemic stroke},\n\tvolume = {14},\n\tjournal = {Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine},\n\tauthor = {Young, Paul and Beasley, Richard and Bailey, Michael and Bellomo, Rinaldo and Eastwood, Glenn and Nichol, Alistair and Pilcher, David and Yunos, Nor'azim and Egi, Moritoki and Hart, Graeme and Reade, Michael and James Cooper, D},\n\tyear = {2012},\n\tpages = {14--19},\n}\n\n
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\n \n\n \n \n \n \n \n Randomized controlled trial of high concentration oxygen in suspected community-acquired pneumonia.\n \n \n \n\n\n \n Wijesinghe, M.; Perrin, K.; Healy, B.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Journal of the Royal Society of Medicine, 105: 208–216. 2012.\n \n\n\n\n
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@article{wijesinghe_randomized_2012,\n\ttitle = {Randomized controlled trial of high concentration oxygen in suspected community-acquired pneumonia},\n\tvolume = {105},\n\tdoi = {10.1258/jrsm.2012.110084},\n\tjournal = {Journal of the Royal Society of Medicine},\n\tauthor = {Wijesinghe, Meme and Perrin, Kyle and Healy, Bridget and Weatherall, Mark and Beasley, Richard},\n\tyear = {2012},\n\tpages = {208--216},\n}\n\n
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\n \n\n \n \n \n \n \n High-concentration versus titrated oxygen therapy in ST-elevation myocardial infarction: A pilot randomized controlled trial.\n \n \n \n\n\n \n Ranchord, A.; Argyle, R.; Beynon, R.; Perrin, K.; Sharma, V.; Weatherall, M.; Simmonds, M.; Heatlie, G.; Brooks, N.; and Beasley, R.\n\n\n \n\n\n\n American heart journal, 163: 168–175. 2012.\n \n\n\n\n
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@article{ranchord_high-concentration_2012,\n\ttitle = {High-concentration versus titrated oxygen therapy in {ST}-elevation myocardial infarction: {A} pilot randomized controlled trial},\n\tvolume = {163},\n\tdoi = {10.1016/j.ahj.2011.10.013},\n\tjournal = {American heart journal},\n\tauthor = {Ranchord, Anil and Argyle, Rachel and Beynon, Rhys and Perrin, Kyle and Sharma, Vishal and Weatherall, Mark and Simmonds, Mark and Heatlie, Grant and Brooks, Nicholas and Beasley, Richard},\n\tyear = {2012},\n\tpages = {168--175},\n}\n\n
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\n \n\n \n \n \n \n \n Delivery of titrated oxygen via a self-inflating resuscitation bag.\n \n \n \n\n\n \n Young, P.; Pilcher, J.; Patel, M.; Cameron, L.; Braithwaite, I.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Resuscitation, 84. 2012.\n \n\n\n\n
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@article{young_delivery_2012,\n\ttitle = {Delivery of titrated oxygen via a self-inflating resuscitation bag},\n\tvolume = {84},\n\tdoi = {10.1016/j.resuscitation.2012.08.330},\n\tjournal = {Resuscitation},\n\tauthor = {Young, Paul and Pilcher, Janine and Patel, Mitesh and Cameron, Laird and Braithwaite, Irene and Weatherall, Mark and Beasley, Richard},\n\tyear = {2012},\n}\n\n
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\n  \n 2011\n \n \n (6)\n \n \n
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\n \n\n \n \n \n \n \n The Effect of Supplemental Oxygen on Hypercapnia in Subjects With Obesity-Associated Hypoventilation A Randomized, Crossover, Clinical Study.\n \n \n \n\n\n \n Wijesinghe, M.; Williams, M.; Perrin, K.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Chest, 139: 1018–1024. 2011.\n \n\n\n\n
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@article{wijesinghe_effect_2011,\n\ttitle = {The {Effect} of {Supplemental} {Oxygen} on {Hypercapnia} in {Subjects} {With} {Obesity}-{Associated} {Hypoventilation} {A} {Randomized}, {Crossover}, {Clinical} {Study}},\n\tvolume = {139},\n\tdoi = {10.1378/chest.10-1280},\n\tjournal = {Chest},\n\tauthor = {Wijesinghe, Meme and Williams, Mathew and Perrin, Kyle and Weatherall, Mark and Beasley, Richard},\n\tyear = {2011},\n\tpages = {1018--1024},\n}\n\n
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\n \n\n \n \n \n \n \n Randomised controlled trial of high concentration versus titrated oxygen therapy in severe exacerbations of asthma.\n \n \n \n\n\n \n Perrin, K.; Wijesinghe, M.; Healy, B.; Wadsworth, K.; Bowditch, R.; Bibby, S.; Baker, T.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Thorax, 66: 937–941. 2011.\n \n\n\n\n
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@article{perrin_randomised_2011,\n\ttitle = {Randomised controlled trial of high concentration versus titrated oxygen therapy in severe exacerbations of asthma},\n\tvolume = {66},\n\tdoi = {10.1136/thx.2010.155259},\n\tjournal = {Thorax},\n\tauthor = {Perrin, Kyle and Wijesinghe, Meme and Healy, Bridget and Wadsworth, Kirsten and Bowditch, Richard and Bibby, Susan and Baker, Tanya and Weatherall, Mark and Beasley, Richard},\n\tyear = {2011},\n\tpages = {937--941},\n}\n\n
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\n \n\n \n \n \n \n \n Randomised controlled crossover trial of the effect on Pt-CO2 of oxygen-driven versus air-driven nebulisers in severe chronic obstructive pulmonary disease.\n \n \n \n\n\n \n Edwards, L.; Perrin, K.; Williams, M.; Weatherall, M.; and Beasley, R.\n\n\n \n\n\n\n Emergency medicine journal : EMJ, 29: 894–898. 2011.\n \n\n\n\n
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@article{edwards_randomised_2011,\n\ttitle = {Randomised controlled crossover trial of the effect on {Pt}-{CO2} of oxygen-driven versus air-driven nebulisers in severe chronic obstructive pulmonary disease},\n\tvolume = {29},\n\tdoi = {10.1136/emermed-2011-200443},\n\tjournal = {Emergency medicine journal : EMJ},\n\tauthor = {Edwards, Llifon and Perrin, Kyle and Williams, Mathew and Weatherall, Mark and Beasley, Richard},\n\tyear = {2011},\n\tpages = {894--898},\n}\n\n
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\n \n\n \n \n \n \n \n High-concentration oxygen therapy in COPD.\n \n \n \n\n\n \n Beasley, R.; Patel, M.; Perrin, K.; and Ronan O'Driscoll, B\n\n\n \n\n\n\n Lancet, 378: 969–970. 2011.\n \n\n\n\n
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@article{beasley_high-concentration_2011,\n\ttitle = {High-concentration oxygen therapy in {COPD}},\n\tvolume = {378},\n\tdoi = {10.1016/S0140-6736(11)61431-1},\n\tjournal = {Lancet},\n\tauthor = {Beasley, Richard and Patel, Mitesh and Perrin, Kyle and Ronan O'Driscoll, B},\n\tyear = {2011},\n\tpages = {969--970},\n}\n\n
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\n \n\n \n \n \n \n \n Arterial oxygen tension and mortality in mechanically ventilated patients.\n \n \n \n\n\n \n Eastwood, G.; Bellomo, R.; Bailey, M.; Taori, G.; Pilcher, D.; Young, P.; and Beasley, R.\n\n\n \n\n\n\n Intensive care medicine, 38: 91–98. 2011.\n \n\n\n\n
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@article{eastwood_arterial_2011,\n\ttitle = {Arterial oxygen tension and mortality in mechanically ventilated patients},\n\tvolume = {38},\n\tdoi = {10.1007/s00134-011-2419-6},\n\tjournal = {Intensive care medicine},\n\tauthor = {Eastwood, Glenn and Bellomo, Rinaldo and Bailey, Michael and Taori, Gopal and Pilcher, David and Young, Paul and Beasley, Richard},\n\tyear = {2011},\n\tpages = {91--98},\n}\n\n
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\n \n\n \n \n \n \n \n A randomised controlled trial of the effect of high concentration oxygen on myocardial ischaemia during exercise.\n \n \n \n\n\n \n Ranchord, A.; Perrin, K.; Weatherall, M.; Beasley, R.; and Simmonds, M.\n\n\n \n\n\n\n International journal of cardiology, 160: 201–205. 2011.\n \n\n\n\n
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@article{ranchord_randomised_2011,\n\ttitle = {A randomised controlled trial of the effect of high concentration oxygen on myocardial ischaemia during exercise},\n\tvolume = {160},\n\tdoi = {10.1016/j.ijcard.2011.04.017},\n\tjournal = {International journal of cardiology},\n\tauthor = {Ranchord, Anil and Perrin, Kyle and Weatherall, Mark and Beasley, Richard and Simmonds, Mark},\n\tyear = {2011},\n\tpages = {201--205},\n}\n
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