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\n \n 2025\n \n \n (1)\n \n \n
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\n\n \n \n \n \n \n Fes-Deficient Macrophages Prime CD8+ T Cells to Stimulate Anti-tumor Immunity and Improve Immunotherapy Efficacy.\n \n \n \n\n\n \n Laight, B. J; Harper, D.; Dmytryk, N.; Zhang, C. S; Shi, C.; Garven, A.; Nauman, R. W; Kment, J.; Alotaibi, F.; Shapovalov, I.; and others\n\n\n \n\n\n\n
Cancer Research. 2025.\n
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@article{laight2025fes,\r\n title={Fes-Deficient Macrophages Prime CD8+ T Cells to Stimulate Anti-tumor Immunity and Improve Immunotherapy Efficacy},\r\n author={Laight, Brian J and Harper, Danielle and Dmytryk, Natasha and Zhang, Connie S and Shi, Changnian and Garven, Andrew and Nauman, Richard W and Kment, Jacob and Alotaibi, Faizah and Shapovalov, Ivan and others},\r\n journal={Cancer Research},\r\n year={2025},\r\n publisher={American Association for Cancer Research}\r\n}\r\n\n
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\n \n 2024\n \n \n (3)\n \n \n
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\n\n \n \n \n \n \n DNA polymerase $ɛ$ and $δ$ variants drive mutagenesis in polypurine tracts in human tumors.\n \n \n \n\n\n \n Ostroverkhova, D.; Tyryshkin, K.; Beach, A. K; Moore, E. A; Masoudi-Sobhanzadeh, Y.; Barbari, S. R; Rogozin, I. B; Shaitan, K. V; Panchenko, A. R; and Shcherbakova, P. V\n\n\n \n\n\n\n
Cell reports, 43(1). 2024.\n
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@article{ostroverkhova2024dna,\r\n title={DNA polymerase $\\varepsilon$ and $\\delta$ variants drive mutagenesis in polypurine tracts in human tumors},\r\n author={Ostroverkhova, Daria and Tyryshkin, Kathrin and Beach, Annette K and Moore, Elizabeth A and Masoudi-Sobhanzadeh, Yosef and Barbari, Stephanie R and Rogozin, Igor B and Shaitan, Konstantin V and Panchenko, Anna R and Shcherbakova, Polina V},\r\n journal={Cell reports},\r\n volume={43},\r\n number={1},\r\n year={2024},\r\n publisher={Elsevier}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Fes-deficient macrophages enhance CD8+ T cell priming and tumour control through increased proinflammatory cytokine production and presentation.\n \n \n \n\n\n \n Laight, B. J; Harper, D.; Dmytryk, N.; Zhang, S.; Garven, A.; Shi, C.; Nauman, R.; Kment, J.; Alotaibi, F.; Gao, Y.; and others\n\n\n \n\n\n\n
bioRxiv,2024–02. 2024.\n
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@article{laight2024fes,\r\n title={Fes-deficient macrophages enhance CD8+ T cell priming and tumour control through increased proinflammatory cytokine production and presentation},\r\n author={Laight, Brian J and Harper, Danielle and Dmytryk, Natasha and Zhang, Shengnan and Garven, Andrew and Shi, Changnian and Nauman, Richard and Kment, Jacob and Alotaibi, Faizah and Gao, Yan and others},\r\n journal={bioRxiv},\r\n pages={2024--02},\r\n year={2024},\r\n publisher={Cold Spring Harbor Laboratory}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n MOLECULAR TRIAGE OF SUSPECTED LUNG CANCER LESIONS THROUGH MICRORNA-BASED LIQUID BIOPSY: FEASIBILITY OF USE IN A LUNG CANCER RAPID ASSESSMENT CLINIC.\n \n \n \n\n\n \n Wang, D. Y.; Damiani, S.; Mayotte, H.; Al-Aboosi, Y.; Fang, A.; Yang, X.; Tyryshkin, K.; Renwick, N.; and Digby, G. C\n\n\n \n\n\n\n
CHEST, 166(4): A4220–A4221. 2024.\n
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@article{wang2024molecular,\r\n title={MOLECULAR TRIAGE OF SUSPECTED LUNG CANCER LESIONS THROUGH MICRORNA-BASED LIQUID BIOPSY: FEASIBILITY OF USE IN A LUNG CANCER RAPID ASSESSMENT CLINIC},\r\n author={Wang, Dong Yao and Damiani, Simona and Mayotte, Harrison and Al-Aboosi, Yousif and Fang, Alexis and Yang, Xiaojing and Tyryshkin, Kathrin and Renwick, Neil and Digby, Genevieve C},\r\n journal={CHEST},\r\n volume={166},\r\n number={4},\r\n pages={A4220--A4221},\r\n year={2024},\r\n publisher={Elsevier}\r\n}\r\n\r\n\n
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\n \n 2023\n \n \n (8)\n \n \n
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\n\n \n \n \n \n \n A transcriptome analysis of basal and stimulated VWF release from endothelial cells derived from patients with type 1 VWD.\n \n \n \n\n\n \n Kloosterman, R.; Zago-Schmitt, M.; Grabell, J.; Thibeault, L.; De Lima, P. A; Bowman, M.; Tyryshkin, K.; Hindmarch, C. C.; Renwick, N.; and James, P.\n\n\n \n\n\n\n
Blood Advances, 7(8): 1477–1487. 2023.\n
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@article{kloosterman2023transcriptome,\r\n title={A transcriptome analysis of basal and stimulated VWF release from endothelial cells derived from patients with type 1 VWD},\r\n author={Kloosterman, Robert and Zago-Schmitt, Matteo and Grabell, Julie and Thibeault, Lisa and De Lima, Patricia A and Bowman, Mackenzie and Tyryshkin, Kathrin and Hindmarch, Charles CT and Renwick, Neil and James, Paula},\r\n journal={Blood Advances},\r\n volume={7},\r\n number={8},\r\n pages={1477--1487},\r\n year={2023},\r\n publisher={American Society of Hematology Washington, DC}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Expression of TCF3 target genes defines a subclass of diffuse large B-cell lymphoma characterized by up-regulation of MYC target genes and poor clinical outcome following R-CHOP therapy.\n \n \n \n\n\n \n Tyryshkin, K.; Moore, A.; Good, D.; Popov, J.; Crocker, S.; Rauh, M. J; Baetz, T.; and LeBrun, D. P\n\n\n \n\n\n\n
Leukemia & Lymphoma, 64(1): 119–129. 2023.\n
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@article{tyryshkin2023expression,\r\n title={Expression of TCF3 target genes defines a subclass of diffuse large B-cell lymphoma characterized by up-regulation of MYC target genes and poor clinical outcome following R-CHOP therapy},\r\n author={Tyryshkin, Kathrin and Moore, Alison and Good, David and Popov, Jesse and Crocker, Susan and Rauh, Michael J and Baetz, Tara and LeBrun, David P},\r\n journal={Leukemia \\& Lymphoma},\r\n volume={64},\r\n number={1},\r\n pages={119--129},\r\n year={2023},\r\n publisher={Taylor \\& Francis}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Establishing the role of the FES tyrosine kinase in the pathogenesis, pathophysiology, and severity of sepsis and its outcomes.\n \n \n \n\n\n \n Laight, B. J; Jawa, N. A; Tyryshkin, K.; Maslove, D. M; Boyd, J G.; and Greer, P. A\n\n\n \n\n\n\n
Frontiers in Immunology, 14: 1145826. 2023.\n
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@article{laight2023establishing,\r\n title={Establishing the role of the FES tyrosine kinase in the pathogenesis, pathophysiology, and severity of sepsis and its outcomes},\r\n author={Laight, Brian J and Jawa, Natasha A and Tyryshkin, Kathrin and Maslove, David M and Boyd, J Gordon and Greer, Peter A},\r\n journal={Frontiers in Immunology},\r\n volume={14},\r\n pages={1145826},\r\n year={2023},\r\n publisher={Frontiers Media SA}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Cancer cell genotype associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in high-grade serous ovarian cancer.\n \n \n \n\n\n \n Shakfa, N.; Li, D.; Conseil, G.; Lightbody, E. D; Wilson-Sanchez, J.; Hamade, A.; Chenard, S.; Jawa, N. A; Laight, B. J; Afriyie-Asante, A.; and others\n\n\n \n\n\n\n
Journal for Immunotherapy of Cancer, 11(4): e006170. 2023.\n
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@article{shakfa2023cancer,\r\n title={Cancer cell genotype associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in high-grade serous ovarian cancer},\r\n author={Shakfa, Noor and Li, Deyang and Conseil, Gwenaelle and Lightbody, Elizabeth D and Wilson-Sanchez, Juliette and Hamade, Ali and Chenard, Stephen and Jawa, Natasha A and Laight, Brian J and Afriyie-Asante, Afrakoma and others},\r\n journal={Journal for Immunotherapy of Cancer},\r\n volume={11},\r\n number={4},\r\n pages={e006170},\r\n year={2023}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Association of Histone H3 Trimethylation in Circulating Monocytes with Lack of Early Recurrence in Patients with Bladder Cancer following BCG Induction Therapy.\n \n \n \n\n\n \n Paré, J.; Tabasinezhad, M.; Grossman, A.; Atallah, A.; Hindmarch, C. C.; Tyryshkin, K.; Siemens, D R.; and Graham, C. H\n\n\n \n\n\n\n
Bladder Cancer, 9(2): 175–186. 2023.\n
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@article{pare2023association,\r\n title={Association of Histone H3 Trimethylation in Circulating Monocytes with Lack of Early Recurrence in Patients with Bladder Cancer following BCG Induction Therapy},\r\n author={Par{\\'e}, Jean-Fran{\\c{c}}cois and Tabasinezhad, Maryam and Grossman, Arielle and Atallah, Aline and Hindmarch, Charles CT and Tyryshkin, Kathrin and Siemens, D Robert and Graham, Charles H},\r\n journal={Bladder Cancer},\r\n volume={9},\r\n number={2},\r\n pages={175--186},\r\n year={2023},\r\n publisher={SAGE Publications Sage UK: London, England}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Methods for Classifying Cancer.\n \n \n \n\n\n \n Renwick, N.; Tyryshkin, K.; Nanayakkara, J.; and Yang, X.\n\n\n \n\n\n\n August 31 2023.\n
US Patent App. 18/015,989\n\n
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@misc{renwick2023methods,\r\n title={Methods for Classifying Cancer},\r\n author={Renwick, Neil and Tyryshkin, Kathrin and Nanayakkara, Jina and Yang, Xiaojing},\r\n year={2023},\r\n month=aug # "~31",\r\n note={US Patent App. 18/015,989}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Increased stromal densities of B cells, CD103+ cells, and CD163+ M2-like macrophages associate with poor clinical outcomes in BCG treated non-muscle invasive bladder cancer.\n \n \n \n\n\n \n Ravenscroft, B.; Yolmo, P.; Chenard, S.; Rahimi, S.; Pace, K.; Sachdeva, K.; Jamaspishvilli, T.; Ghaedi, H.; Garven, A.; Tyryshkin, K.; and others\n\n\n \n\n\n\n
bioRxiv,2023–10. 2023.\n
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@article{ravenscroft2023increased,\r\n title={Increased stromal densities of B cells, CD103+ cells, and CD163+ M2-like macrophages associate with poor clinical outcomes in BCG treated non-muscle invasive bladder cancer},\r\n author={Ravenscroft, Benjamin and Yolmo, Priyanka and Chenard, Stephen and Rahimi, Sadaf and Pace, Keiran and Sachdeva, Kartik and Jamaspishvilli, Tamara and Ghaedi, Hamid and Garven, Andrew and Tyryshkin, Kathrin and others},\r\n journal={bioRxiv},\r\n pages={2023--10},\r\n year={2023},\r\n publisher={Cold Spring Harbor Laboratory}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n A user-driven machine learning approach for RNA-based sample discrimination and hierarchical classification.\n \n \n \n\n\n \n Imtiaz, T.; Nanayakkara, J.; Fang, A.; Jomaa, D.; Mayotte, H.; Damiani, S.; Javed, F.; Jones, T.; Kaczmarek, E.; Adebayo, F. O.; and others\n\n\n \n\n\n\n
STAR protocols, 4(4): 102661. 2023.\n
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@article{imtiaz2023user,\r\n title={A user-driven machine learning approach for RNA-based sample discrimination and hierarchical classification},\r\n author={Imtiaz, Tashifa and Nanayakkara, Jina and Fang, Alexis and Jomaa, Danny and Mayotte, Harrison and Damiani, Simona and Javed, Fiza and Jones, Tristan and Kaczmarek, Emily and Adebayo, Flourish Omolara and others},\r\n journal={STAR protocols},\r\n volume={4},\r\n number={4},\r\n pages={102661},\r\n year={2023},\r\n publisher={Elsevier}\r\n}\r\n\r\n\n
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\n \n 2022\n \n \n (6)\n \n \n
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\n\n \n \n \n \n \n High interobserver variability and frequent overdiagnosis of dysplasia in fundic gland polyps can be improved by detecting atypia on the surface epithelium and an abrupt transition to non-neoplastic cells.\n \n \n \n\n\n \n Orr, C. E; Beneck, D.; Jessurun, J.; Qin, L.; Tyryshkin, K.; Yantiss, R. K; and Chen, Y.\n\n\n \n\n\n\n
Histopathology, 80(2): 314–321. 2022.\n
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@article{orr2022high,\r\n title={High interobserver variability and frequent overdiagnosis of dysplasia in fundic gland polyps can be improved by detecting atypia on the surface epithelium and an abrupt transition to non-neoplastic cells},\r\n author={Orr, Christine E and Beneck, Debra and Jessurun, Jose and Qin, Lihui and Tyryshkin, Kathrin and Yantiss, Rhonda K and Chen, Yao-Tseng},\r\n journal={Histopathology},\r\n volume={80},\r\n number={2},\r\n pages={314--321},\r\n year={2022}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Discriminating neoplastic from nonneoplastic tissues using an miRNA-based deep cancer classifier.\n \n \n \n\n\n \n Kaczmarek, E.; Pyman, B.; Nanayakkara, J.; Tuschl, T.; Tyryshkin, K.; Renwick, N.; and Mousavi, P.\n\n\n \n\n\n\n
The American Journal of Pathology, 192(2): 344–352. 2022.\n
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@article{kaczmarek2022discriminating,\r\n title={Discriminating neoplastic from nonneoplastic tissues using an miRNA-based deep cancer classifier},\r\n author={Kaczmarek, Emily and Pyman, Blake and Nanayakkara, Jina and Tuschl, Thomas and Tyryshkin, Kathrin and Renwick, Neil and Mousavi, Parvin},\r\n journal={The American Journal of Pathology},\r\n volume={192},\r\n number={2},\r\n pages={344--352},\r\n year={2022},\r\n publisher={Elsevier}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Sex differences in the aging murine urinary bladder and influence on the tumor immune microenvironment of a carcinogen-induced model of bladder cancer.\n \n \n \n\n\n \n Hamade, A.; Li, D.; Tyryshkin, K.; Xu, M.; Conseil, G.; Yolmo, P.; Hamilton, J.; Chenard, S.; Robert Siemens, D; and Koti, M.\n\n\n \n\n\n\n
Biology of sex Differences, 13(1): 19. 2022.\n
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@article{hamade2022sex,\r\n title={Sex differences in the aging murine urinary bladder and influence on the tumor immune microenvironment of a carcinogen-induced model of bladder cancer},\r\n author={Hamade, Ali and Li, Deyang and Tyryshkin, Kathrin and Xu, Minqi and Conseil, Gwenaelle and Yolmo, Priyanka and Hamilton, Jake and Chenard, Stephen and Robert Siemens, D and Koti, Madhuri},\r\n journal={Biology of sex Differences},\r\n volume={13},\r\n number={1},\r\n pages={19},\r\n year={2022},\r\n publisher={BioMed Central London}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n PTEN and BRCA1 tumor suppressor loss associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in a murine model of ovarian cancer.\n \n \n \n\n\n \n Shakfa, N.; Li, D.; Conseil, G.; Lightbody, E.; Wilson-Sanchez, J.; Hamade, A.; Chenard, S.; Laight, B.; Afriyie-Asante, A.; Tyryshkin, K.; and others\n\n\n \n\n\n\n
bioRxiv,2022–06. 2022.\n
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@article{shakfa2022pten,\r\n title={PTEN and BRCA1 tumor suppressor loss associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in a murine model of ovarian cancer},\r\n author={Shakfa, Noor and Li, Deyang and Conseil, Gwena{\\"e}lle and Lightbody, Elizabeth and Wilson-Sanchez, Juliette and Hamade, Ali and Chenard, Stephen and Laight, Brian and Afriyie-Asante, Afrakoma and Tyryshkin, Kathrin and others},\r\n journal={bioRxiv},\r\n pages={2022--06},\r\n year={2022},\r\n publisher={Cold Spring Harbor Laboratory}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n A computational approach to identification of candidate biomarkers in high-dimensional molecular data.\n \n \n \n\n\n \n Gerolami, J.; Wong, J. J. M.; Zhang, R.; Chen, T.; Imtiaz, T.; Smith, M.; Jamaspishvili, T.; Koti, M.; Glasgow, J. I.; Mousavi, P.; and others\n\n\n \n\n\n\n
Diagnostics, 12(8): 1997. 2022.\n
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@article{gerolami2022computational,\r\n title={A computational approach to identification of candidate biomarkers in high-dimensional molecular data},\r\n author={Gerolami, Justin and Wong, Justin Jong Mun and Zhang, Ricky and Chen, Tong and Imtiaz, Tashifa and Smith, Miranda and Jamaspishvili, Tamara and Koti, Madhuri and Glasgow, Janice Irene and Mousavi, Parvin and others},\r\n journal={Diagnostics},\r\n volume={12},\r\n number={8},\r\n pages={1997},\r\n year={2022},\r\n publisher={MDPI}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n miRNA-Based Cancer Classifier from TCGA Expression Profiles.\n \n \n \n\n\n \n Imtiaz, T.; Patel, D.; Wong, J. J.; Tyryshkin, K.; and Renwick, N.\n\n\n \n\n\n\n
The FASEB Journal, 36. 2022.\n
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@article{imtiaz2022mirna,\r\n title={miRNA-Based Cancer Classifier from TCGA Expression Profiles},\r\n author={Imtiaz, Tashifa and Patel, Dhruv and Wong, Justin JM and Tyryshkin, Kathrin and Renwick, Neil},\r\n journal={The FASEB Journal},\r\n volume={36},\r\n year={2022},\r\n publisher={The Federation of American Societies for Experimental Biology}\r\n}\r\n\r\n\n
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\n \n 2021\n \n \n (7)\n \n \n
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\n\n \n \n \n \n \n Lack of definitive presurgical pathological diagnosis is associated with inadequate surgical margins in breast-conserving surgery.\n \n \n \n\n\n \n Fauerbach, P. V N.; Tyryshkin, K.; Rodrigo, S. P.; Rudan, J.; Fichtinger, G.; Reedijk, M.; Varma, S.; and Berman, D. M\n\n\n \n\n\n\n
European Journal of Surgical Oncology, 47(10): 2483–2491. 2021.\n
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@article{fauerbach2021lack,\r\n title={Lack of definitive presurgical pathological diagnosis is associated with inadequate surgical margins in breast-conserving surgery},\r\n author={Fauerbach, Paola V Nasute and Tyryshkin, Kathrin and Rodrigo, Silvia Perez and Rudan, John and Fichtinger, Gabor and Reedijk, Michael and Varma, Sonal and Berman, David M},\r\n journal={European Journal of Surgical Oncology},\r\n volume={47},\r\n number={10},\r\n pages={2483--2491},\r\n year={2021},\r\n publisher={WB Saunders}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Investigating the age and sex associated mucosal immune landscape of urinary bladder.\n \n \n \n\n\n \n Hamade, A.; Li, D.; Tyryshkin, K.; Shakfa, N. E; Chenard, S.; Siemens, R.; and Koti, M.\n\n\n \n\n\n\n
The Journal of Immunology, 206(1_Supplement): 55–07. 2021.\n
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@article{hamade2021investigating,\r\n title={Investigating the age and sex associated mucosal immune landscape of urinary bladder},\r\n author={Hamade, Ali and Li, Deyang and Tyryshkin, Kathrin and Shakfa, Noor E and Chenard, Stephen and Siemens, Robert and Koti, Madhuri},\r\n journal={The Journal of Immunology},\r\n volume={206},\r\n number={1\\_Supplement},\r\n pages={55--07},\r\n year={2021},\r\n publisher={American Association of Immunologists}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n STING pathway mediated immunologic consequences of DNA damage repair gene losses in high-grade serous ovarian tumors.\n \n \n \n\n\n \n Shakfa, N. E; Lightbody, E.; Li, D.; Wilson-Sanchez, J.; Afriyie-Asante, A.; Chenard, S.; Hamade, A.; Tyryshkin, K.; and Koti, M.\n\n\n \n\n\n\n
The Journal of Immunology, 206(1_Supplement): 67–03. 2021.\n
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@article{shakfa2021sting,\r\n title={STING pathway mediated immunologic consequences of DNA damage repair gene losses in high-grade serous ovarian tumors},\r\n author={Shakfa, Noor E and Lightbody, Elizabeth and Li, Deyang and Wilson-Sanchez, Juliette and Afriyie-Asante, Afrakoma and Chenard, Stephen and Hamade, Ali and Tyryshkin, Kathrin and Koti, Madhuri},\r\n journal={The Journal of Immunology},\r\n volume={206},\r\n number={1\\_Supplement},\r\n pages={67--03},\r\n year={2021},\r\n publisher={American Association of Immunologists}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n The influence of age and sex on the pre-treatment immune microenvironment of a carcinogen induced murine model of bladder cancer.\n \n \n \n\n\n \n Hamade, A.; Li, D.; Tyryshkin, K.; Xu, M.; Chenard, S.; Conseil, G.; Yolmo, P.; Siemens, D R.; and Koti, M.\n\n\n \n\n\n\n
bioRxiv,2021–09. 2021.\n
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@article{hamade2021influence,\r\n title={The influence of age and sex on the pre-treatment immune microenvironment of a carcinogen induced murine model of bladder cancer},\r\n author={Hamade, Ali and Li, Deyang and Tyryshkin, Kathrin and Xu, Minqi and Chenard, Stephen and Conseil, Gwenaelle and Yolmo, Priyanka and Siemens, D Robert and Koti, Madhuri},\r\n journal={bioRxiv},\r\n pages={2021--09},\r\n year={2021},\r\n publisher={Cold Spring Harbor Laboratory}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n not otherwise specified; LVI, lymphovascular invasion; ILC, invasive Address:. 16pvnf@ queensu. ca (PV Nasute Fauerbach), kt40@ queensu. ca (K.\n \n \n \n\n\n \n Fauerbach, P. V; Tyryshkin, K.; Perez Rodrigo, S.; Rudan, J.; Fichtinger, G.; Reedijk, M.; Varma, S.; and Berman, D. M\n\n\n \n\n\n\n
EJSO, 47(10): 2483–2491. 2021.\n
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@article{fauerbach2021not,\r\n title={not otherwise specified; LVI, lymphovascular invasion; ILC, invasive Address:. 16pvnf@ queensu. ca (PV Nasute Fauerbach), kt40@ queensu. ca (K.},\r\n author={Fauerbach, Paola V and Tyryshkin, Kathrin and Perez Rodrigo, Silvia and Rudan, John and Fichtinger, Gabor and Reedijk, Michael and Varma, Sonal and Berman, David M},\r\n journal={EJSO},\r\n volume={47},\r\n number={10},\r\n pages={2483--2491},\r\n year={2021},\r\n publisher={ELSEVIER SCI LTD THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB~…}\r\n}\r\n\r\n\n
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\n \n 2020\n \n \n (8)\n \n \n
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\n\n \n \n \n \n \n Neutrophil recruitment and function in endometriosis patients and a syngeneic murine model.\n \n \n \n\n\n \n Symons, L. K; Miller, J. E; Tyryshkin, K.; Monsanto, S. P; Marks, R. M; Lingegowda, H.; Vanderbeck, K.; Childs, T.; Young, S. L; Lessey, B. A; and others\n\n\n \n\n\n\n
The FASEB Journal, 34(1): 1558–1575. 2020.\n
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@article{symons2020neutrophil,\r\n title={Neutrophil recruitment and function in endometriosis patients and a syngeneic murine model},\r\n author={Symons, Lindsey K and Miller, Jessica E and Tyryshkin, Kathrin and Monsanto, Stephany P and Marks, Ryan M and Lingegowda, Harshavardhan and Vanderbeck, Kaitlin and Childs, Timothy and Young, Steven L and Lessey, Bruce A and others},\r\n journal={The FASEB Journal},\r\n volume={34},\r\n number={1},\r\n pages={1558--1575},\r\n year={2020}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Objective quantification of BCL2 protein by multiplex immunofluorescence in routine biopsy samples of diffuse large B-cell lymphoma demonstrates associations with survival and BCL2 gene alterations.\n \n \n \n\n\n \n Chen, L.; Tyryshkin, K.; Moore, A.; Scott, D. W; Steidl, C.; Li, Y.; Shepherd, L. E; Rauh, M.; Deng, L.; Good, D.; and others\n\n\n \n\n\n\n
Leukemia & Lymphoma, 61(6): 1334–1344. 2020.\n
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@article{chen2020objective,\r\n title={Objective quantification of BCL2 protein by multiplex immunofluorescence in routine biopsy samples of diffuse large B-cell lymphoma demonstrates associations with survival and BCL2 gene alterations},\r\n author={Chen, Lina and Tyryshkin, Kathrin and Moore, Alison and Scott, David W and Steidl, Christian and Li, Yi and Shepherd, Lois E and Rauh, Michael and Deng, Lan and Good, David and others},\r\n journal={Leukemia \\& Lymphoma},\r\n volume={61},\r\n number={6},\r\n pages={1334--1344},\r\n year={2020},\r\n publisher={Taylor \\& Francis}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n MicroRNA-Based Classification of Neuroendocrine Neoplasms.\n \n \n \n\n\n \n Vanderbeck, K.; Nanayakkara, J.; Tyryshkin, K.; Wong, J.; Yang, X.; Ginter, P.; Scognamiglio, T.; and Renwick, N.\n\n\n \n\n\n\n In
LABORATORY INVESTIGATION, volume 100, pages 832–833, 2020. NATURE PUBLISHING GROUP 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA\n
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@inproceedings{vanderbeck2020microrna,\r\n title={MicroRNA-Based Classification of Neuroendocrine Neoplasms},\r\n author={Vanderbeck, Kaitlin and Nanayakkara, Jina and Tyryshkin, Kathrin and Wong, Justin and Yang, Xiaojing and Ginter, Paula and Scognamiglio, Theresa and Renwick, Neil},\r\n booktitle={LABORATORY INVESTIGATION},\r\n volume={100},\r\n number={SUPPL 1},\r\n pages={832--833},\r\n year={2020},\r\n organization={NATURE PUBLISHING GROUP 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n MicroRNA-Based Classification of Neuroendocrine Neoplasms.\n \n \n \n\n\n \n Nanayakkara, J.; Tyryshkin, K.; Yang, X.; Wong, J.; Tuschl, T.; and Renwick, N.\n\n\n \n\n\n\n In
PANCREAS, volume 49, pages 481–481, 2020. LIPPINCOTT WILLIAMS & WILKINS TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA …\n
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@inproceedings{nanayakkara2020microrna,\r\n title={MicroRNA-Based Classification of Neuroendocrine Neoplasms},\r\n author={Nanayakkara, Jina and Tyryshkin, Kathrin and Yang, Xiaojing and Wong, Justin and Tuschl, Thomas and Renwick, Neil},\r\n booktitle={PANCREAS},\r\n volume={49},\r\n number={3},\r\n pages={481--481},\r\n year={2020},\r\n organization={LIPPINCOTT WILLIAMS \\& WILKINS TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA~…}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Characterizing and classifying neuroendocrine neoplasms through microRNA sequencing and data mining.\n \n \n \n\n\n \n Nanayakkara, J.; Tyryshkin, K.; Yang, X.; Wong, J. J.; Vanderbeck, K.; Ginter, P. S; Scognamiglio, T.; Chen, Y.; Panarelli, N.; Cheung, N.; and others\n\n\n \n\n\n\n
NAR cancer, 2(3): zcaa009. 2020.\n
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@article{nanayakkara2020characterizing,\r\n title={Characterizing and classifying neuroendocrine neoplasms through microRNA sequencing and data mining},\r\n author={Nanayakkara, Jina and Tyryshkin, Kathrin and Yang, Xiaojing and Wong, Justin JM and Vanderbeck, Kaitlin and Ginter, Paula S and Scognamiglio, Theresa and Chen, Yao-Tseng and Panarelli, Nicole and Cheung, Nai-Kong and others},\r\n journal={NAR cancer},\r\n volume={2},\r\n number={3},\r\n pages={zcaa009},\r\n year={2020},\r\n publisher={Oxford University Press}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Classifying lung neuroendocrine neoplasms through microRNA Sequence Data Mining.\n \n \n \n\n\n \n Wong, J. J.; Ginter, P. S; Tyryshkin, K.; Yang, X.; Nanayakkara, J.; Zhou, Z.; Tuschl, T.; Chen, Y.; and Renwick, N.\n\n\n \n\n\n\n
Cancers, 12(9): 2653. 2020.\n
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@article{wong2020classifying,\r\n title={Classifying lung neuroendocrine neoplasms through microRNA Sequence Data Mining},\r\n author={Wong, Justin JM and Ginter, Paula S and Tyryshkin, Kathrin and Yang, Xiaojing and Nanayakkara, Jina and Zhou, Zier and Tuschl, Thomas and Chen, Yao-Tseng and Renwick, Neil},\r\n journal={Cancers},\r\n volume={12},\r\n number={9},\r\n pages={2653},\r\n year={2020},\r\n publisher={MDPI}\r\n}\r\n\r\n\n
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\n \n 2019\n \n \n (5)\n \n \n
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\n\n \n \n \n \n \n Evaluating gastroenteropancreatic neuroendocrine tumors through microRNA sequencing.\n \n \n \n\n\n \n Panarelli, N.; Tyryshkin, K.; Wong, J. J. M.; Majewski, A.; Yang, X.; Scognamiglio, T.; Kim, M. K.; Bogardus, K.; Tuschl, T.; Chen, Y.; and others\n\n\n \n\n\n\n
Endocrine-related cancer, 26(1): 47–57. 2019.\n
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@article{panarelli2019evaluating,\r\n title={Evaluating gastroenteropancreatic neuroendocrine tumors through microRNA sequencing},\r\n author={Panarelli, Nicole and Tyryshkin, Kathrin and Wong, Justin Jong Mun and Majewski, Adrianna and Yang, Xiaojing and Scognamiglio, Theresa and Kim, Michelle Kang and Bogardus, Kimberly and Tuschl, Thomas and Chen, Yao-Tseng and others},\r\n journal={Endocrine-related cancer},\r\n volume={26},\r\n number={1},\r\n pages={47--57},\r\n year={2019},\r\n publisher={Bioscientifica Ltd}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Plasma microRNA expression levels and their targeted pathways in patients with major depressive disorder who are responsive to duloxetine treatment.\n \n \n \n\n\n \n Kim, H. K.; Tyryshkin, K.; Elmi, N.; Dharsee, M.; Evans, K. R; Good, J.; Javadi, M.; McCormack, S.; Vaccarino, A. L; Zhang, X.; and others\n\n\n \n\n\n\n
Journal of Psychiatric Research, 110: 38–44. 2019.\n
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@article{kim2019plasma,\r\n title={Plasma microRNA expression levels and their targeted pathways in patients with major depressive disorder who are responsive to duloxetine treatment},\r\n author={Kim, Helena Kyunghee and Tyryshkin, Kathrin and Elmi, Nika and Dharsee, Moyez and Evans, Kenneth R and Good, Jennifer and Javadi, Mojib and McCormack, Stephanie and Vaccarino, Anthony L and Zhang, Xiao and others},\r\n journal={Journal of Psychiatric Research},\r\n volume={110},\r\n pages={38--44},\r\n year={2019},\r\n publisher={Pergamon}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Validation of diagnostic gene sets to identify critically ill patients with sepsis.\n \n \n \n\n\n \n Maslove, D. M; Shapira, T.; Tyryshkin, K.; Veldhoen, R. A; Marshall, J. C; and Muscedere, J.\n\n\n \n\n\n\n
Journal of Critical Care, 49: 92–98. 2019.\n
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@article{maslove2019validation,\r\n title={Validation of diagnostic gene sets to identify critically ill patients with sepsis},\r\n author={Maslove, David M and Shapira, Tal and Tyryshkin, Kathrin and Veldhoen, Richard A and Marshall, John C and Muscedere, John},\r\n journal={Journal of Critical Care},\r\n volume={49},\r\n pages={92--98},\r\n year={2019},\r\n publisher={WB Saunders}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Response to Letter to the Editor (Mangioni et al).\n \n \n \n\n\n \n Maslove, D. M; Shapira, T.; Tyryshkin, K.; Veldhoen, R. A; Marshall, J. C; and Muscedere, J.\n\n\n \n\n\n\n
Journal of critical care, 52: 269. 2019.\n
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@article{maslove2019response,\r\n title={Response to Letter to the Editor (Mangioni et al)},\r\n author={Maslove, David M and Shapira, Tal and Tyryshkin, Kathrin and Veldhoen, Richard A and Marshall, John C and Muscedere, John},\r\n journal={Journal of critical care},\r\n volume={52},\r\n pages={269},\r\n year={2019}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Classifying and Grading Archived Gastrointestinal Neuroendocrine Tumors Through microRNA Sequencing.\n \n \n \n\n\n \n Panarelli, N.; Tyryshkin, K.; Wong, J.; Yang, X.; Kim, M.; Tuschl, T.; Chen, Y.; and Renwick, N.\n\n\n \n\n\n\n In
PANCREAS, volume 48, pages 447–447, 2019. LIPPINCOTT WILLIAMS & WILKINS TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA …\n
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@inproceedings{panarelli2019classifying,\r\n title={Classifying and Grading Archived Gastrointestinal Neuroendocrine Tumors Through microRNA Sequencing},\r\n author={Panarelli, Nicole and Tyryshkin, Kathrin and Wong, Justin and Yang, Xiaojing and Kim, Michelle and Tuschl, Thomas and Chen, Yao-Tseng and Renwick, Neil},\r\n booktitle={PANCREAS},\r\n volume={48},\r\n number={3},\r\n pages={447--447},\r\n year={2019},\r\n organization={LIPPINCOTT WILLIAMS \\& WILKINS TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA~…}\r\n}\r\n\r\n\n
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\n \n 2018\n \n \n (7)\n \n \n
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\n\n \n \n \n \n \n Overexpression of Arginase 1 is linked to DNMT3A and TET2 mutations in lower-grade myelodysplastic syndromes and chronic myelomonocytic leukemia.\n \n \n \n\n\n \n Cull, A.; Mahendru, D; Snetsinger, B; Good, D; Tyryshkin, K; Chesney, A; Ghorab, Z; Reis, M; Buckstein, R; Wells, R.; and others\n\n\n \n\n\n\n
Leukemia Research, 65: 5–13. 2018.\n
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@article{cull2018overexpression,\r\n title={Overexpression of Arginase 1 is linked to DNMT3A and TET2 mutations in lower-grade myelodysplastic syndromes and chronic myelomonocytic leukemia},\r\n author={Cull, AH and Mahendru, D and Snetsinger, B and Good, D and Tyryshkin, K and Chesney, A and Ghorab, Z and Reis, M and Buckstein, R and Wells, RA and others},\r\n journal={Leukemia Research},\r\n volume={65},\r\n pages={5--13},\r\n year={2018},\r\n publisher={Pergamon}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Examining redox modulation pathways in the post-mortem frontal cortex in patients with bipolar disorder through data mining of microRNA expression datasets.\n \n \n \n\n\n \n Kim, H. K.; Tyryshkin, K.; Elmi, N.; Feilotter, H.; and Andreazza, A. C.\n\n\n \n\n\n\n
Journal of Psychiatric Research, 99: 39–49. 2018.\n
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@article{kim2018examining,\r\n title={Examining redox modulation pathways in the post-mortem frontal cortex in patients with bipolar disorder through data mining of microRNA expression datasets},\r\n author={Kim, Helena Kyunghee and Tyryshkin, Kathrin and Elmi, Nika and Feilotter, Harriet and Andreazza, Ana Cristina},\r\n journal={Journal of Psychiatric Research},\r\n volume={99},\r\n pages={39--49},\r\n year={2018},\r\n publisher={Pergamon}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Data mining study of microRNA expression datasets from the post-mortem frontal cortex examining redox modulation pathways in patients with bipolar disorder.\n \n \n \n\n\n \n Kim, H; Tyryshkin, K; Elmi, N; Feilotter, H; and Andreazza, A.\n\n\n \n\n\n\n In
BIPOLAR DISORDERS, volume 20, pages 111–111, 2018. WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA\n
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@inproceedings{kim2018data,\r\n title={Data mining study of microRNA expression datasets from the post-mortem frontal cortex examining redox modulation pathways in patients with bipolar disorder},\r\n author={Kim, H and Tyryshkin, K and Elmi, N and Feilotter, H and Andreazza, AC},\r\n booktitle={BIPOLAR DISORDERS},\r\n volume={20},\r\n pages={111--111},\r\n year={2018},\r\n organization={WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Objective Quantification of BCL2 Protein and Transcript in Routine Biopsy Samples Demonstrates Associations with BCL2 Translocation, BCL2 Copy Number Increase, and Response to R-CHOP in Patients with Diffuse Large B-cell Lymphoma.\n \n \n \n\n\n \n Chen, L.; Li, Y.; Tyryshkin, K.; Deng, L.; Scott, D.; Rauh, M.; Crocker, S.; Baetz, T.; and LeBrun, D.\n\n\n \n\n\n\n In
LABORATORY INVESTIGATION, volume 98, pages 506–506, 2018. NATURE PUBLISHING GROUP 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA\n
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@inproceedings{chen2018objective,\r\n title={Objective Quantification of BCL2 Protein and Transcript in Routine Biopsy Samples Demonstrates Associations with BCL2 Translocation, BCL2 Copy Number Increase, and Response to R-CHOP in Patients with Diffuse Large B-cell Lymphoma},\r\n author={Chen, Lina and Li, Yi and Tyryshkin, Kathrin and Deng, Lan and Scott, David and Rauh, Michael and Crocker, Susan and Baetz, Tara and LeBrun, David},\r\n booktitle={LABORATORY INVESTIGATION},\r\n volume={98},\r\n pages={506--506},\r\n year={2018},\r\n organization={NATURE PUBLISHING GROUP 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Novel prognostic and predictive microRNA targets for triple-negative breast cancer.\n \n \n \n\n\n \n Turashvili, G.; Lightbody, E. D; Tyryshkin, K.; SenGupta, S. K; Elliott, B. E; Madarnas, Y.; Ghaffari, A.; Day, A.; and Nicol, C. J.\n\n\n \n\n\n\n
The FASEB Journal, 32(11): 5937–5954. 2018.\n
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@article{turashvili2018novel,\r\n title={Novel prognostic and predictive microRNA targets for triple-negative breast cancer},\r\n author={Turashvili, Gulisa and Lightbody, Elizabeth D and Tyryshkin, Kathrin and SenGupta, Sandip K and Elliott, Bruce E and Madarnas, Yolanda and Ghaffari, Abdi and Day, Andrew and Nicol, Christopher JB},\r\n journal={The FASEB Journal},\r\n volume={32},\r\n number={11},\r\n pages={5937--5954},\r\n year={2018},\r\n publisher={Federation of American Societies for Experimental Biology}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Exploring microRNA regulation of cancer with context-aware deep cancer classifier.\n \n \n \n\n\n \n Pyman, B.; Sedghi, A.; Azizi, S.; Tyryshkin, K.; Renwick, N.; and Mousavi, P.\n\n\n \n\n\n\n In
BIOCOMPUTING 2019: Proceedings of the Pacific Symposium, pages 160–171, 2018. \n
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@inproceedings{pyman2018exploring,\r\n title={Exploring microRNA regulation of cancer with context-aware deep cancer classifier},\r\n author={Pyman, Blake and Sedghi, Alireza and Azizi, Shekoofeh and Tyryshkin, Kathrin and Renwick, Neil and Mousavi, Parvin},\r\n booktitle={BIOCOMPUTING 2019: Proceedings of the Pacific Symposium},\r\n pages={160--171},\r\n year={2018}\r\n}\r\n\r\n\n
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\n \n 2017\n \n \n (6)\n \n \n
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\n\n \n \n \n \n \n MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.\n \n \n \n\n\n \n Lopez, J. P.; Fiori, L. M; Cruceanu, C.; Lin, R.; Labonte, B.; Cates, H. M; Heller, E. A; Vialou, V.; Ku, S. M; Gerald, C.; and others\n\n\n \n\n\n\n
Nature communications, 8(1): 15497. 2017.\n
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@article{lopez2017micrornas,\r\n title={MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes},\r\n author={Lopez, Juan Pablo and Fiori, Laura M and Cruceanu, Cristiana and Lin, Rixing and Labonte, Benoit and Cates, Hannah M and Heller, Elizabeth A and Vialou, Vincent and Ku, Stacy M and Gerald, Christophe and others},\r\n journal={Nature communications},\r\n volume={8},\r\n number={1},\r\n pages={15497},\r\n year={2017},\r\n publisher={Nature Publishing Group UK London}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n BCL2 mRNA or protein abundance is superior to gene rearrangement status in predicting clinical outcomes in patients with diffuse large B-cell lymphoma.\n \n \n \n\n\n \n Li, Y; Tyryshkin, K; Good, D; Farmer, P; Scott, D.; Crocker, S; Baetz, T; and LeBrun, D\n\n\n \n\n\n\n
Hematological Oncology, 35: 288–289. 2017.\n
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\n
@article{li2017bcl2,\r\n title={BCL2 mRNA or protein abundance is superior to gene rearrangement status in predicting clinical outcomes in patients with diffuse large B-cell lymphoma},\r\n author={Li, Y and Tyryshkin, K and Good, D and Farmer, P and Scott, DW and Crocker, S and Baetz, T and LeBrun, D},\r\n journal={Hematological Oncology},\r\n volume={35},\r\n pages={288--289},\r\n year={2017}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n The role of micrornas in regulating redox modulation in bipolar disorder.\n \n \n \n\n\n \n Kim, H; Tyryshkin, K; Elmi, N; Oliviera, V; Andreazza, A; and Feilotter, H\n\n\n \n\n\n\n
European Psychiatry, 41(S1): S119–S119. 2017.\n
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\n
@article{kim2017role,\r\n title={The role of micrornas in regulating redox modulation in bipolar disorder},\r\n author={Kim, H and Tyryshkin, K and Elmi, N and Oliviera, V and Andreazza, A and Feilotter, H},\r\n journal={European Psychiatry},\r\n volume={41},\r\n number={S1},\r\n pages={S119--S119},\r\n year={2017},\r\n publisher={Cambridge University Press}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n COMPREHENSIVE IMMUNE TRANSCRIPTOMIC ANALYSIS IN BLADDER CANCER REVEALS SUBTYPE SPECIFIC IMMUNE GENE EXPRESSION PATTERNS: MP88-05.\n \n \n \n\n\n \n Siemens, D; Ren, R.; Tyryshkin, K.; and Koti, M.\n\n\n \n\n\n\n
Journal of Urology, 197(4): e1175–e1176. 2017.\n
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@article{siemens2017comprehensive,\r\n title={COMPREHENSIVE IMMUNE TRANSCRIPTOMIC ANALYSIS IN BLADDER CANCER REVEALS SUBTYPE SPECIFIC IMMUNE GENE EXPRESSION PATTERNS: MP88-05},\r\n author={Siemens, D and Ren, Runhan and Tyryshkin, Kathrin and Koti, Madhuri},\r\n journal={Journal of Urology},\r\n volume={197},\r\n number={4},\r\n pages={e1175--e1176},\r\n year={2017},\r\n publisher={LWW}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Comprehensive immune transcriptomic analysis in bladder cancer reveals subtype specific immune gene expression patterns of prognostic relevance.\n \n \n \n\n\n \n Ren, R.; Tyryshkin, K.; Graham, C. H; Koti, M.; and Siemens, D R.\n\n\n \n\n\n\n
Oncotarget, 8(41): 70982. 2017.\n
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@article{ren2017comprehensive,\r\n title={Comprehensive immune transcriptomic analysis in bladder cancer reveals subtype specific immune gene expression patterns of prognostic relevance},\r\n author={Ren, Runhan and Tyryshkin, Kathrin and Graham, Charles H and Koti, Madhuri and Siemens, D Robert},\r\n journal={Oncotarget},\r\n volume={8},\r\n number={41},\r\n pages={70982},\r\n year={2017}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Differential expression of miRNAs in lung neuroendocrine tumours using barcoded small RNA sequencing.\n \n \n \n\n\n \n Ginter, P. S; Barsoum, I. B; Yang, X.; Tyryshkin, K.; Scognamiglio, T.; Panarelli, N. C; Tuschl, T.; Renwick, N.; and Chen, Y.\n\n\n \n\n\n\n
Canadian Journal of Pathology, 9. 2017.\n
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@article{ginter2017differential,\r\n title={Differential expression of miRNAs in lung neuroendocrine tumours using barcoded small RNA sequencing.},\r\n author={Ginter, Paula S and Barsoum, Ivraym B and Yang, Xiaojing and Tyryshkin, Kathrin and Scognamiglio, Theresa and Panarelli, Nicole C and Tuschl, Thomas and Renwick, Neil and Chen, Yao-Tseng},\r\n journal={Canadian Journal of Pathology},\r\n volume={9},\r\n year={2017}\r\n}\r\n\r\n\n
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\n \n 2016\n \n \n (6)\n \n \n
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\n\n \n \n \n \n \n microRNA-guided diagnostics in clinical samples.\n \n \n \n\n\n \n Gustafson, D.; Tyryshkin, K.; and Renwick, N.\n\n\n \n\n\n\n
Best practice & research Clinical endocrinology & metabolism, 30(5): 563–575. 2016.\n
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@article{gustafson2016microrna,\r\n title={microRNA-guided diagnostics in clinical samples},\r\n author={Gustafson, Dakota and Tyryshkin, Kathrin and Renwick, Neil},\r\n journal={Best practice \\& research Clinical endocrinology \\& metabolism},\r\n volume={30},\r\n number={5},\r\n pages={563--575},\r\n year={2016},\r\n publisher={Bailli{\\`e}re Tindall}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Differential expression of TCF3 target genes defines subclasses of diffuse large B-cell lymphoma with striking differences in clinical outcome following R-CHOP therapy.\n \n \n \n\n\n \n Tyryshkin, K.; Li, Y. D; Good, D.; Shepherd, L. E; Baetz, T.; Rauh, M. J; and LeBrun, D. P\n\n\n \n\n\n\n
Blood, 128(22): 3037. 2016.\n
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@article{tyryshkin2016differential,\r\n title={Differential expression of TCF3 target genes defines subclasses of diffuse large B-cell lymphoma with striking differences in clinical outcome following R-CHOP therapy},\r\n author={Tyryshkin, Kathrin and Li, Yi D and Good, David and Shepherd, Lois E and Baetz, Tara and Rauh, Michael J and LeBrun, David P},\r\n journal={Blood},\r\n volume={128},\r\n number={22},\r\n pages={3037},\r\n year={2016},\r\n publisher={Content Repository Only!}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Objective Quantification of BCL2 by Immunofluorescence in Routine Biopsy Samples Predicts Response to R-CHOP and Overall Survival in Diffuse Large B-Cell Lymphoma.\n \n \n \n\n\n \n Li, Y.; Tyryshkin, K.; Allan, D.; Mansoor, S. A.; Baetz, T.; LeBrun, D. P; Akhter, A.; and Oh, D.\n\n\n \n\n\n\n In
LABORATORY INVESTIGATION, volume 96, pages 359A–359A, 2016. NATURE PUBLISHING GROUP 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA\n
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@inproceedings{li2016objective,\r\n title={Objective Quantification of BCL2 by Immunofluorescence in Routine Biopsy Samples Predicts Response to R-CHOP and Overall Survival in Diffuse Large B-Cell Lymphoma},\r\n author={Li, Yi and Tyryshkin, Kathrin and Allan, Douglas and Mansoor, Stewart Adnan and Baetz, Tara and LeBrun, David P and Akhter, Ariz and Oh, Danielle},\r\n booktitle={LABORATORY INVESTIGATION},\r\n volume={96},\r\n pages={359A--359A},\r\n year={2016},\r\n organization={NATURE PUBLISHING GROUP 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Genetic fitness and selection intensity in a population affected with high-incidence spinocerebellar ataxia type 1.\n \n \n \n\n\n \n Platonov, F. A; Tyryshkin, K.; Tikhonov, D. G; Neustroyeva, T. S; Sivtseva, T. M; Yakovleva, N. V; Nikolaev, V. P; Sidorova, O. G; Kononova, S. K; Goldfarb, L. G; and others\n\n\n \n\n\n\n
Neurogenetics, 17: 179–185. 2016.\n
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@article{platonov2016genetic,\r\n title={Genetic fitness and selection intensity in a population affected with high-incidence spinocerebellar ataxia type 1},\r\n author={Platonov, Fedor A and Tyryshkin, Kathrin and Tikhonov, Dmitriy G and Neustroyeva, Tatyana S and Sivtseva, Tatyana M and Yakovleva, Natalya V and Nikolaev, Valerian P and Sidorova, Oksana G and Kononova, Sardana K and Goldfarb, Lev G and others},\r\n journal={Neurogenetics},\r\n volume={17},\r\n pages={179--185},\r\n year={2016},\r\n publisher={Springer Berlin Heidelberg}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n A Small Panel of microRNAs Effectively Separates Typical Carcinoids from Neuroendocrine Carcinomas and May Predict Outcome in Atypical Carcinoid Tumors.\n \n \n \n\n\n \n Chen, Y.; Yang, X.; Tyryshkin, K.; Ginter, P.; Tuschl, T.; and Renwick, N.\n\n\n \n\n\n\n In
LABORATORY INVESTIGATION, volume 96, pages 468A–468A, 2016. NATURE PUBLISHING GROUP 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA\n
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@inproceedings{chen2016small,\r\n title={A Small Panel of microRNAs Effectively Separates Typical Carcinoids from Neuroendocrine Carcinomas and May Predict Outcome in Atypical Carcinoid Tumors},\r\n author={Chen, Yao-Tseng and Yang, Xiaojing and Tyryshkin, Kathrin and Ginter, Paula and Tuschl, Thomas and Renwick, Neil},\r\n booktitle={LABORATORY INVESTIGATION},\r\n volume={96},\r\n pages={468A--468A},\r\n year={2016},\r\n organization={NATURE PUBLISHING GROUP 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Improving prostate cancer risk assessment using pre-treatment clinical and pathological variables.\n \n \n \n\n\n \n Jamaspishvili, T.; Tyryshkin, K.; How, N.; Patel, P.; and Berman, D. M\n\n\n \n\n\n\n
Canadian Journal of Pathology, 8. 2016.\n
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@article{jamaspishvili2016improving,\r\n title={Improving prostate cancer risk assessment using pre-treatment clinical and pathological variables.},\r\n author={Jamaspishvili, Tamara and Tyryshkin, Kathrin and How, Nathan and Patel, Palak and Berman, David M},\r\n journal={Canadian Journal of Pathology},\r\n volume={8},\r\n year={2016}\r\n}\r\n\r\n\n
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\n \n 2015\n \n \n (2)\n \n \n
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\n \n 2014\n \n \n (2)\n \n \n
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\n\n \n \n \n \n \n A robotic object hitting task to quantify sensorimotor impairments in participants with stroke.\n \n \n \n\n\n \n Tyryshkin, K.; Coderre, A. M; Glasgow, J. I; Herter, T. M; Bagg, S. D; Dukelow, S. P; and Scott, S. H\n\n\n \n\n\n\n
Journal of neuroengineering and rehabilitation, 11: 1–12. 2014.\n
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@article{tyryshkin2014robotic,\r\n title={A robotic object hitting task to quantify sensorimotor impairments in participants with stroke},\r\n author={Tyryshkin, Kathrin and Coderre, Angela M and Glasgow, Janice I and Herter, Troy M and Bagg, Stephen D and Dukelow, Sean P and Scott, Stephen H},\r\n journal={Journal of neuroengineering and rehabilitation},\r\n volume={11},\r\n pages={1--12},\r\n year={2014},\r\n publisher={BioMed Central}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Advanced Techniques for Robotic Assessment of Neurological Impairments In Stroke Patients.\n \n \n \n\n\n \n Tyryshkin, K.\n\n\n \n\n\n\n Ph.D. Thesis, 2014.\n
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@phdthesis{tyryshkin2014advanced,\r\n title={Advanced Techniques for Robotic Assessment of Neurological Impairments In Stroke Patients},\r\n author={Tyryshkin, Kathrin},\r\n year={2014}\r\n}\r\n\r\n\n
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\n \n 2013\n \n \n (1)\n \n \n
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\n\n \n \n \n \n \n Hand usage and inter-limb coordination parameters for the bimanual rapid visuomotor task to quantify sensorimotor dysfunction of participants with stroke.\n \n \n \n\n\n \n Tyryshkin, K.; Dukelow, S. P; Glasgow, J. I; and Scott, S. H\n\n\n \n\n\n\n
BMC Neuroscience, 14: 1–2. 2013.\n
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@article{tyryshkin2013hand,\r\n title={Hand usage and inter-limb coordination parameters for the bimanual rapid visuomotor task to quantify sensorimotor dysfunction of participants with stroke},\r\n author={Tyryshkin, Kathrin and Dukelow, Sean P and Glasgow, Janice I and Scott, Stephen H},\r\n journal={BMC Neuroscience},\r\n volume={14},\r\n pages={1--2},\r\n year={2013},\r\n publisher={BioMed Central}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n SELECTED PAPERS USING THE KINARM ROBOT FOR STUDY OF HUMAN BEHAVIOUR.\n \n \n \n\n\n \n Kenzie, J.; Semrau, J.; Findlater, S.; Herter, T.; Scott, S.; Dukelow, S.; Lowrey, C.; Jackson, C.; Bagg, S; Fung, D; and others\n\n\n \n\n\n\n
therapy, 36(2): 58–67. 2012.\n
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@article{kenzie2012selected,\r\n title={SELECTED PAPERS USING THE KINARM ROBOT FOR STUDY OF HUMAN BEHAVIOUR},\r\n author={Kenzie, JM and Semrau, JA and Findlater, SE and Herter, TM and Scott, SH and Dukelow, SP and Lowrey, CR and Jackson, CPT and Bagg, S and Fung, D and others},\r\n journal={therapy},\r\n volume={36},\r\n number={2},\r\n pages={58--67},\r\n year={2012}\r\n}\r\n\r\n\n
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\n \n 2011\n \n \n (1)\n \n \n
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\n\n \n \n \n \n \n Robotic assessment of visuomotor control and position sense in patients with hemispatial neglect.\n \n \n \n\n\n \n Herter, T; Tyryshkin, K; Bourque, M; Scott, S.; and Dukelow, S.\n\n\n \n\n\n\n In
STROKE, volume 42, pages E612–E612, 2011. LIPPINCOTT WILLIAMS & WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA\n
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@inproceedings{herter2011robotic,\r\n title={Robotic assessment of visuomotor control and position sense in patients with hemispatial neglect},\r\n author={Herter, T and Tyryshkin, K and Bourque, M and Scott, SH and Dukelow, SP},\r\n booktitle={STROKE},\r\n volume={42},\r\n number={11},\r\n pages={E612--E612},\r\n year={2011},\r\n organization={LIPPINCOTT WILLIAMS \\& WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA}\r\n}\r\n\r\n\n
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\n \n 2009\n \n \n (1)\n \n \n
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\n\n \n \n \n \n \n Evaluation of stroke impairment using time series analysis.\n \n \n \n\n\n \n Tyryshkin, K.; Glasgow, J. I; and Scott, S. H\n\n\n \n\n\n\n
BMC Neuroscience, 10(Suppl 1): P331. 2009.\n
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@article{tyryshkin2009evaluation,\r\n title={Evaluation of stroke impairment using time series analysis},\r\n author={Tyryshkin, Kathrin and Glasgow, Janice I and Scott, Stephen H},\r\n journal={BMC Neuroscience},\r\n volume={10},\r\n number={Suppl 1},\r\n pages={P331},\r\n year={2009},\r\n publisher={BioMed Central London}\r\n}\r\n\r\n\n
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\n \n 2007\n \n \n (3)\n \n \n
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\n\n \n \n \n \n \n A navigation system for shoulder arthroscopic surgery.\n \n \n \n\n\n \n Tyryshkin, K; Mousavi, P; Beek, M; Ellis, R.; Pichora, D.; and Abolmaesumi, P\n\n\n \n\n\n\n
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 221(7): 801–812. 2007.\n
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@article{tyryshkin2007navigation,\r\n title={A navigation system for shoulder arthroscopic surgery},\r\n author={Tyryshkin, K and Mousavi, P and Beek, M and Ellis, RE and Pichora, DR and Abolmaesumi, P},\r\n journal={Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine},\r\n volume={221},\r\n number={7},\r\n pages={801--812},\r\n year={2007},\r\n publisher={SAGE Publications Sage UK: London, England}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Computer-assisted navigation system for shoulder arthroscopic surgery.\n \n \n \n\n\n \n Tyryshkin, K.\n\n\n \n\n\n\n Ph.D. Thesis, Library and Archives Canada= Bibliothèque et Archives Canada, Ottawa, 2007.\n
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@phdthesis{tyryshkin2007computer,\r\n title={Computer-assisted navigation system for shoulder arthroscopic surgery.},\r\n author={Tyryshkin, Kathrin},\r\n year={2007},\r\n school={Library and Archives Canada= Bibliothèque et Archives Canada, Ottawa}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n A novel graphical user interface for ultrasound-guided shoulder arthroscopic surgery.\n \n \n \n\n\n \n Tyryshkin, K.; Mousavi, P.; Beek, M.; Pichora, D; and Abolmaesumi, P.\n\n\n \n\n\n\n In
Medical Imaging 2007: Visualization and Image-Guided Procedures, volume 6509, pages 341–349, 2007. SPIE\n
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@inproceedings{tyryshkin2007novel,\r\n title={A novel graphical user interface for ultrasound-guided shoulder arthroscopic surgery},\r\n author={Tyryshkin, Kathrin and Mousavi, Purang and Beek, Maarten and Pichora, D and Abolmaesumi, Purang},\r\n booktitle={Medical Imaging 2007: Visualization and Image-Guided Procedures},\r\n volume={6509},\r\n pages={341--349},\r\n year={2007},\r\n organization={SPIE}\r\n}\r\n\r\n\n
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\n \n 2006\n \n \n (4)\n \n \n
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\n\n \n \n \n \n \n Identification of anatomical landmarks for registration of CT and ultrasound images in computer-assisted shoulder arthroscopy.\n \n \n \n\n\n \n Tyryshkin, K.; Mousavi, P.; Pichora, D. R; and Abolmaesumi, P.\n\n\n \n\n\n\n In
2006 International Conference of the IEEE Engineering in Medicine and Biology Society, pages 416–419, 2006. IEEE\n
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@inproceedings{tyryshkin2006identification,\r\n title={Identification of anatomical landmarks for registration of CT and ultrasound images in computer-assisted shoulder arthroscopy},\r\n author={Tyryshkin, Kathrin and Mousavi, Parvin and Pichora, David R and Abolmaesumi, Purang},\r\n booktitle={2006 International Conference of the IEEE Engineering in Medicine and Biology Society},\r\n pages={416--419},\r\n year={2006},\r\n organization={IEEE}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n A novel ultrasound-guided shoulder arthroscopic surgery.\n \n \n \n\n\n \n Tyryshkin, K.; Mousavi, P.; Beek, M.; Chen, T; Pichora, D; and Abolmaesumi, P.\n\n\n \n\n\n\n In
Medical Imaging 2006: Visualization, Image-Guided Procedures, and Display, volume 6141, pages 767–774, 2006. SPIE\n
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@inproceedings{tyryshkin2006novel,\r\n title={A novel ultrasound-guided shoulder arthroscopic surgery},\r\n author={Tyryshkin, Kathrin and Mousavi, Purang and Beek, Maarten and Chen, T and Pichora, D and Abolmaesumi, Purang},\r\n booktitle={Medical Imaging 2006: Visualization, Image-Guided Procedures, and Display},\r\n volume={6141},\r\n pages={767--774},\r\n year={2006},\r\n organization={SPIE}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Anatomical landmarks for optimal registration using ultrasound in navigated shoulder arthroscopy.\n \n \n \n\n\n \n Tyryshkin, K; Mousavi, P; Pichora, D.; and Abolmaesumi, P\n\n\n \n\n\n\n In
Proceedings of 6th Annual Meeting of CAOS-International, pages 543–546, 2006. \n
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@inproceedings{tyryshkin2006anatomical,\r\n title={Anatomical landmarks for optimal registration using ultrasound in navigated shoulder arthroscopy},\r\n author={Tyryshkin, K and Mousavi, P and Pichora, DR and Abolmaesumi, P},\r\n booktitle={Proceedings of 6th Annual Meeting of CAOS-International},\r\n pages={543--546},\r\n year={2006}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n A novel ultrasound-guided shoulder arthroscopic surgery [6141-94].\n \n \n \n\n\n \n Tyryshkin, K; Mousavi, P; Beek, M; Chen, T; Pichora, D; and Abolmaesumi, P\n\n\n \n\n\n\n In
PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, volume 6141, pages 61412L, 2006. International Society for Optical Engineering; 1999\n
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@inproceedings{tyryshkin2006novel,\r\n title={A novel ultrasound-guided shoulder arthroscopic surgery [6141-94]},\r\n author={Tyryshkin, K and Mousavi, P and Beek, M and Chen, T and Pichora, D and Abolmaesumi, P},\r\n booktitle={PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING},\r\n volume={6141},\r\n pages={61412L},\r\n year={2006},\r\n organization={International Society for Optical Engineering; 1999}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Manual Alignment of CT and Ultrasound Images for Computer-Assisted Shoulder Arthroscopy.\n \n \n \n\n\n \n Tyryshkin, K; Mousavi, P; Abolmaesumi, P; and Pichora, D\n\n\n \n\n\n\n . .\n
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@article{tyryshkinmanual,\r\n title={Manual Alignment of CT and Ultrasound Images for Computer-Assisted Shoulder Arthroscopy},\r\n author={Tyryshkin, K and Mousavi, P and Abolmaesumi, P and Pichora, D},\r\n publisher={Citeseer}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Evaluation of New Parameters for Assessment of Stroke Impairment.\n \n \n \n\n\n \n Tyryshkin, K.; Glasgow, J. I; and Scott, S. H\n\n\n \n\n\n\n
Thursday May 20,71. .\n
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@article{tyryshkin20evaluation,\r\n title={Evaluation of New Parameters for Assessment of Stroke Impairment},\r\n author={Tyryshkin, Kathrin and Glasgow, Janice I and Scott, Stephen H},\r\n journal={Thursday May 20},\r\n pages={71}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n A NOVEL INTERFACE FOR ULTRASOUND-GUIDED SHOULDER ARTHROSCOPY.\n \n \n \n\n\n \n Pichora, D; Abolmaesumi, P; Tyryshkin, K; Beek, M; Chen, T; and Mousavi, P\n\n\n \n\n\n\n . .\n
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@article{pichoranovel,\r\n title={A NOVEL INTERFACE FOR ULTRASOUND-GUIDED SHOULDER ARTHROSCOPY},\r\n author={Pichora, D and Abolmaesumi, P and Tyryshkin, K and Beek, M and Chen, T and Mousavi, P}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n Fractal Time-Series Analysis of Reaching Motion in Stroke Affected Arms.\n \n \n \n\n\n \n King, T. F; Tyryshkin, K.; and Glasgow, J. I\n\n\n \n\n\n\n
Thursday May 20,99. .\n
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@article{king20fractal,\r\n title={Fractal Time-Series Analysis of Reaching Motion in Stroke Affected Arms},\r\n author={King, Tanny F and Tyryshkin, Kathrin and Glasgow, Janice I},\r\n journal={Thursday May 20},\r\n pages={99}\r\n}\r\n\r\n\n
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\n\n \n \n \n \n \n of mutations in A: T and G: C sites during the affinity maturation of immunoglobulin genes. Previously, we demonstrated that AID contributes to mutagenesis in (de) methylated genomic DNA in various cancers. Our current analysis of methylation data from malignant lymphomas suggests that driver genes are subject to different (de) methylation processes than non-driver genes and, in addition to AID, the activity of pols $η$ and $θ$.\n \n \n \n\n\n \n Rogozin, I. B; Roche-Lima, A.; Tyryshkin, K.; Carrasquillo-Carrión, K.; Lada, A. G; Poliakov, L. Y; Schwartz, E.; Saura, A.; Yurchenko, V.; Cooper, D. N; and others\n\n\n \n\n\n\n . .\n
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@article{rogozinmutations,\r\n title={of mutations in A: T and G: C sites during the affinity maturation of immunoglobulin genes. Previously, we demonstrated that AID contributes to mutagenesis in (de) methylated genomic DNA in various cancers. Our current analysis of methylation data from malignant lymphomas suggests that driver genes are subject to different (de) methylation processes than non-driver genes and, in addition to AID, the activity of pols $\\eta$ and $\\theta$},\r\n author={Rogozin, Igor B and Roche-Lima, Abiel and Tyryshkin, Kathrin and Carrasquillo-Carri{\\'o}n, Kelvin and Lada, Artem G and Poliakov, Lennard Y and Schwartz, Elena and Saura, Andreu and Yurchenko, Vyacheslav and Cooper, David N and others}\r\n}\r\n\r\n\n
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