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\n \n 2026\n \n \n (3)\n \n \n
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\n\n \n \n \n \n \n Structured factorization for single-cell gene expression data.\n \n \n \n\n\n \n Canale, A.; Galtarossa, L.; Risso, D.; Schiavon, L.; and Toto, G.\n\n\n \n\n\n\n
Journal of the Royal Statistical Society Series C: Applied Statistics,qlag009. 2026.\n
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@article{canale2023structured,\n title={Structured factorization for single-cell gene expression data},\n author={Canale, Antonio and Galtarossa, Luisa and Risso, Davide and Schiavon, Lorenzo and Toto, Giovanni},\n journal={Journal of the Royal Statistical Society Series C: Applied Statistics},\n year={2026},\n pages={qlag009}\n}\n\n\n
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\n\n \n \n \n \n \n A Latent Activated Olfactory Stem Cell State Revealed by Single-Cell Transcriptomic and Epigenomic Profiling.\n \n \n \n\n\n \n Van den Berge, K.; Bakalar, D.; Chou, H.; Kunda, D.; Risso, D.; Street, K.; Purdom, E.; Dudoit, S.; Ngai, J.; and Heavner, W.\n\n\n \n\n\n\n
Stem Cell Reports, 21: 102778. 2026.\n
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@article{van2025latent,\n title={A Latent Activated Olfactory Stem Cell State Revealed by Single-Cell Transcriptomic and Epigenomic Profiling},\n author={Van den Berge, Koen and Bakalar, Dana and Chou, Hsin-Jung and Kunda, Divya and Risso, Davide and Street, Kelly and Purdom, Elizabeth and Dudoit, Sandrine and Ngai, John and Heavner, Whitney},\n journal={Stem Cell Reports},\n volume={21},\n pages={102778},\n year={2026}\n}\n\n\n
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\n \n 2025\n \n \n (10)\n \n \n
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\n\n \n \n \n \n \n Guided structure learning of DAGs for count data.\n \n \n \n\n\n \n Nguyen, T. K. H.; Chiogna, M.; Risso, D.; and Banzato, E.\n\n\n \n\n\n\n
Statistical Modelling, 25(4): 366–390. 2025.\n
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@article{nguyen2025guided,\n title={Guided structure learning of DAGs for count data},\n author={Nguyen, Thi Kim Hue and Chiogna, Monica and Risso, Davide and Banzato, Erika},\n journal={Statistical Modelling},\n volume={25},\n number={4},\n pages={366--390},\n year={2025},\n publisher={Sage Publications Sage India: New Delhi, India}\n}\n\n\n
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\n\n \n \n \n \n \n Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles.\n \n \n \n\n\n \n Bhinder, B.; Friedl, V.; Sethuraman, S.; Risso, D.; Chiotti, K. E; Mashl, R J.; Ellrott, K. P; Lee, J. A; Wong, C. K; Gyan, K.; and others\n\n\n \n\n\n\n
Scientific Reports, 15(1): 23921. 2025.\n
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@article{bhinder2025pan,\n title={Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles},\n author={Bhinder, Bhavneet and Friedl, Verena and Sethuraman, Sunantha and Risso, Davide and Chiotti, Kami E and Mashl, R Jay and Ellrott, Kyle P and Lee, Jordan A and Wong, Christopher K and Gyan, Kofi and others},\n journal={Scientific Reports},\n volume={15},\n number={1},\n pages={23921},\n year={2025},\n publisher={Nature Publishing Group UK London}\n}\n\n\n
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\n\n \n \n \n \n \n Bioconductor’s Computational Ecosystem for Genomic Data Science in Cancer.\n \n \n \n\n\n \n Ramos, M.; Shepherd, L.; Sheffield, N. C; Mahmoud, A.; Pagès, H.; Wokaty, A.; Righelli, D.; Risso, D.; Davis, S.; Oh, S.; and others\n\n\n \n\n\n\n
Cancer Bioinformatics,1–46. 2025.\n
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@article{ramos2012bioconductor,\n title={Bioconductor’s Computational Ecosystem for Genomic Data Science in Cancer},\n author={Ramos, Marcel and Shepherd, Lori and Sheffield, Nathan C and Mahmoud, Alexandru and Pag{\\`e}s, Herv{\\'e} and Wokaty, Andres and Righelli, Dario and Risso, Davide and Davis, Sean and Oh, Sehyun and others},\n journal={Cancer Bioinformatics},\n pages={1--46},\n year={2025},\n publisher={Springer US New York, NY}\n}\n\n\n\n
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\n\n \n \n \n \n \n Spatially Regularized Gaussian Mixtures for Clustering Spatial Transcriptomic Data.\n \n \n \n\n\n \n Sottosanti, A.; Risso, D.; and Denti, F.\n\n\n \n\n\n\n
Journal of Classification,1–23. 2025.\n
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@article{sottosanti2025spatially,\n title={Spatially Regularized Gaussian Mixtures for Clustering Spatial Transcriptomic Data},\n author={Sottosanti, Andrea and Risso, Davide and Denti, Francesco},\n journal={Journal of Classification},\n pages={1--23},\n year={2025},\n publisher={Springer US}\n}\n\n\n
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\n\n \n \n \n \n \n Benchmarking large-scale single-cell RNA-seq analysis.\n \n \n \n\n\n \n Billato, I.; Pages, H.; Carey, V.; Waldron, L.; Sales, G.; Romualdi, C.; and Risso, D.\n\n\n \n\n\n\n
bioRxiv,2025–10. 2025.\n
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@article{billato2025benchmarking,\n title={Benchmarking large-scale single-cell RNA-seq analysis},\n author={Billato, Ilaria and Pages, Herve and Carey, Vince and Waldron, Levi and Sales, Gabriele and Romualdi, Chiara and Risso, Davide},\n journal={bioRxiv},\n pages={2025--10},\n year={2025},\n publisher={Cold Spring Harbor Laboratory}\n}\n\n\n
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\n\n \n \n \n \n \n Orchestrating Spatial Transcriptomics Analysis with Bioconductor.\n \n \n \n\n\n \n Crowell, H. L; Dong, Y.; Billato, I.; Cai, P.; Emons, M.; Gunz, S.; Guo, B.; Li, M.; Mahmoud, A.; Manukyan, A.; and others\n\n\n \n\n\n\n
bioRxiv,2025–11. 2025.\n
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@article{crowell2025orchestrating,\n title={Orchestrating Spatial Transcriptomics Analysis with Bioconductor},\n author={Crowell, Helena L and Dong, Yixing and Billato, Ilaria and Cai, Peiying and Emons, Martin and Gunz, Samuel and Guo, Boyi and Li, Mengbo and Mahmoud, Alexandru and Manukyan, Art{\\"u}r and others},\n journal={bioRxiv},\n pages={2025--11},\n year={2025},\n publisher={Cold Spring Harbor Laboratory}\n}\n\n\n
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\n\n \n \n \n \n \n SpaceTrooper: a quality control framework for imaging-based spatial omics data.\n \n \n \n\n\n \n Banzi, B.; Righelli, D.; Marchionni, M.; Romano, O.; Forcato, M.; Risso, D.; and Bicciato, S.\n\n\n \n\n\n\n
bioRxiv,2025–12. 2025.\n
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@article{banzi2025spacetrooper,\n title={SpaceTrooper: a quality control framework for imaging-based spatial omics data},\n author={Banzi, Benedetta and Righelli, Dario and Marchionni, Matteo and Romano, Oriana and Forcato, Mattia and Risso, Davide and Bicciato, Silvio},\n journal={bioRxiv},\n pages={2025--12},\n year={2025},\n publisher={Cold Spring Harbor Laboratory}\n}\n\n
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\n \n 2024\n \n \n (5)\n \n \n
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\n\n \n \n \n \n \n Improving replicability in single-cell RNA-Seq cell type discovery with Dune.\n \n \n \n\n\n \n de Bézieux, H. R.; Street, K.; Fischer, S.; Van den Berge, K.; Chance, R.; Risso, D.; Gillis, J.; Ngai, J.; Purdom, E.; and Dudoit, S.\n\n\n \n\n\n\n
BMC Bioinformatics, 25: 198. 2024.\n
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@article{de2020improving,\n title={Improving replicability in single-cell RNA-Seq cell type discovery with Dune},\n author={de B{\\'e}zieux, Hector Roux and Street, Kelly and Fischer, Stephan and Van den Berge, Koen and Chance, Rebecca and Risso, Davide and Gillis, Jesse and Ngai, John and Purdom, Elizabeth and Dudoit, Sandrine},\n journal={BMC Bioinformatics},\n volume={25},\n pages={198},\n year={2024},\n publisher={Cold Spring Harbor Laboratory}\n}\n\n\n
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\n\n \n \n \n \n \n A global transcriptional atlas of the effect of acute sleep deprivation in the mouse frontal cortex.\n \n \n \n\n\n \n Ford, K.; Zuin, E.; Righelli, D.; Medina, E.; Schoch, H.; Singletary, K.; Muheim, C.; Frank, M. G; Hicks, S. C; Risso, D.; and others\n\n\n \n\n\n\n
iScience, 27(9). 2024.\n
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@article{ford2024global,\n title={A global transcriptional atlas of the effect of acute sleep deprivation in the mouse frontal cortex},\n author={Ford, Kaitlyn and Zuin, Elena and Righelli, Dario and Medina, Elizabeth and Schoch, Hannah and Singletary, Kristan and Muheim, Christine and Frank, Marcos G and Hicks, Stephanie C and Risso, Davide and others},\n journal={iScience},\n volume={27},\n number={9},\n year={2024},\n publisher={Elsevier}\n}\n\n\n
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\n\n \n \n \n \n \n Exploring public cancer gene expression signatures across bulk, single-cell and spatial transcriptomics data with signifinder Bioconductor package.\n \n \n \n\n\n \n Pirrotta, S.; Masatti, L.; Bortolato, A.; Corrà, A.; Pedrini, F.; Aere, M.; Esposito, G.; Martini, P.; Risso, D.; Romualdi, C.; and others\n\n\n \n\n\n\n
NAR Genomics and Bioinformatics, 6(4): lqae138. 2024.\n
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@article{pirrotta2024exploring,\n title={Exploring public cancer gene expression signatures across bulk, single-cell and spatial transcriptomics data with signifinder Bioconductor package},\n author={Pirrotta, Stefania and Masatti, Laura and Bortolato, Anna and Corr{\\`a}, Anna and Pedrini, Fabiola and Aere, Martina and Esposito, Giovanni and Martini, Paolo and Risso, Davide and Romualdi, Chiara and others},\n journal={NAR Genomics and Bioinformatics},\n volume={6},\n number={4},\n pages={lqae138},\n year={2024},\n publisher={Oxford University Press}\n}\n\n\n
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\n\n \n \n \n \n \n Stochastic gradient descent estimation of generalized matrix factorization models with application to single-cell RNA sequencing data.\n \n \n \n\n\n \n Castiglione, C.; Segers, A.; Clement, L.; and Risso, D.\n\n\n \n\n\n\n
arXiv preprint arXiv:2412.20509. 2024.\n
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@article{castiglione2024stochastic,\n title={Stochastic gradient descent estimation of generalized matrix factorization models with application to single-cell RNA sequencing data},\n author={Castiglione, Cristian and Segers, Alexandre and Clement, Lieven and Risso, Davide},\n journal={arXiv preprint arXiv:2412.20509},\n year={2024}\n}\n\n\n
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\n \n 2023\n \n \n (6)\n \n \n
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\n\n \n \n \n \n \n Structure learning for zero-inflated counts with an application to single-cell RNA sequencing data.\n \n \n \n\n\n \n Nguyen, T. K. H.; Van den Berge, K.; Chiogna, M.; and Risso, D.\n\n\n \n\n\n\n
The Annals of Applied Statistics, 17(3): 2555–2573. 2023.\n
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@article{nguyen2023structure,\n title={Structure learning for zero-inflated counts with an application to single-cell RNA sequencing data},\n author={Nguyen, Thi Kim Hue and Van den Berge, Koen and Chiogna, Monica and Risso, Davide},\n journal={The Annals of Applied Statistics},\n volume={17},\n number={3},\n pages={2555--2573},\n year={2023},\n publisher={Institute of Mathematical Statistics}\n}\n\n\n
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\n\n \n \n \n \n \n Co-clustering of spatially resolved transcriptomic data.\n \n \n \n\n\n \n Sottosanti, A.; and Risso, D.\n\n\n \n\n\n\n
The Annals of Applied Statistics, 17(2): 1444. 2023.\n
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@article{sottosanti2023co,\n title={Co-clustering of spatially resolved transcriptomic data},\n author={Sottosanti, Andrea and Risso, Davide},\n journal={The Annals of Applied Statistics},\n volume={17},\n number={2},\n pages={1444},\n year={2023}\n}\n\n\n
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\n\n \n \n \n \n \n Curated single cell multimodal landmark datasets for R/Bioconductor.\n \n \n \n\n\n \n Eckenrode, K. B; Righelli, D.; Ramos, M.; Argelaguet, R.; Vanderaa, C.; Geistlinger, L.; Culhane, A. C; Gatto, L.; Carey, V.; Morgan, M.; and others\n\n\n \n\n\n\n
PLOS Computational Biology, 19(8): e1011324. 2023.\n
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@article{eckenrode2023curated,\n title={Curated single cell multimodal landmark datasets for R/Bioconductor},\n author={Eckenrode, Kelly B and Righelli, Dario and Ramos, Marcel and Argelaguet, Ricard and Vanderaa, Christophe and Geistlinger, Ludwig and Culhane, Aedin C and Gatto, Laurent and Carey, Vincent and Morgan, Martin and others},\n journal={PLOS Computational Biology},\n volume={19},\n number={8},\n pages={e1011324},\n year={2023},\n publisher={Public Library of Science San Francisco, CA USA}\n}\n\n\n
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\n\n \n \n \n \n \n A Bartlett-type correction for likelihood ratio tests with application to testing equality of Gaussian graphical models.\n \n \n \n\n\n \n Banzato, E.; Chiogna, M.; Djordjilović, V.; and Risso, D.\n\n\n \n\n\n\n
Statistics & Probability Letters, 193: 109732. 2023.\n
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@article{banzato2023bartlett,\n title={A Bartlett-type correction for likelihood ratio tests with application to testing equality of Gaussian graphical models},\n author={Banzato, Erika and Chiogna, Monica and Djordjilovi{\\'c}, Vera and Risso, Davide},\n journal={Statistics \\& Probability Letters},\n volume={193},\n pages={109732},\n year={2023},\n publisher={North-Holland}\n}\n\n\n
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\n\n \n \n \n \n \n Designing spatial transcriptomic experiments.\n \n \n \n\n\n \n Righelli, D.; Sottosanti, A.; and Risso, D.\n\n\n \n\n\n\n
Nature Methods, 20(3): 355–356. 2023.\n
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@article{righelli2023designing,\n title={Designing spatial transcriptomic experiments},\n author={Righelli, Dario and Sottosanti, Andrea and Risso, Davide},\n journal={Nature Methods},\n volume={20},\n number={3},\n pages={355--356},\n year={2023},\n publisher={Nature Publishing Group US New York}\n}\n\n\n
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\n \n 2022\n \n \n (5)\n \n \n
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\n\n \n \n \n \n \n Normalization benchmark of ATAC-seq datasets shows the importance of accounting for GC-content effects.\n \n \n \n\n\n \n Van den Berge, K.; Chou, H.; de Bézieux, H. R.; Street, K.; Risso, D.; Ngai, J.; and Dudoit, S.\n\n\n \n\n\n\n
Cell Reports Methods, 2(11). 2022.\n
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@article{van2022normalization,\n title={Normalization benchmark of ATAC-seq datasets shows the importance of accounting for GC-content effects},\n author={Van den Berge, Koen and Chou, Hsin-Jung and de B{\\'e}zieux, Hector Roux and Street, Kelly and Risso, Davide and Ngai, John and Dudoit, Sandrine},\n journal={Cell Reports Methods},\n volume={2},\n number={11},\n year={2022},\n publisher={Elsevier}\n}\n\n\n
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\n\n \n \n \n \n \n SpatialExperiment: infrastructure for spatially-resolved transcriptomics data in R using Bioconductor.\n \n \n \n\n\n \n Righelli, D.; Weber, L. M; Crowell, H. L; Pardo, B.; Collado-Torres, L.; Ghazanfar, S.; Lun, A. T.; Hicks, S. C; and Risso, D.\n\n\n \n\n\n\n
Bioinformatics, 38(11): 3128–3131. 2022.\n
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@article{righelli2022spatialexperiment,\n title={SpatialExperiment: infrastructure for spatially-resolved transcriptomics data in R using Bioconductor},\n author={Righelli, Dario and Weber, Lukas M and Crowell, Helena L and Pardo, Brenda and Collado-Torres, Leonardo and Ghazanfar, Shila and Lun, Aaron TL and Hicks, Stephanie C and Risso, Davide},\n journal={Bioinformatics},\n volume={38},\n number={11},\n pages={3128--3131},\n year={2022},\n publisher={Oxford University Press}\n}\n\n\n
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\n\n \n \n \n \n \n PsiNorm: a scalable normalization for single-cell RNA-seq data.\n \n \n \n\n\n \n Borella, M.; Martello, G.; Risso, D.; and Romualdi, C.\n\n\n \n\n\n\n
Bioinformatics, 38(1): 164–172. 2022.\n
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@article{borella2022psinorm,\n title={PsiNorm: a scalable normalization for single-cell RNA-seq data},\n author={Borella, Matteo and Martello, Graziano and Risso, Davide and Romualdi, Chiara},\n journal={Bioinformatics},\n volume={38},\n number={1},\n pages={164--172},\n year={2022},\n publisher={Oxford University Press}\n}\n\n\n\n
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\n\n \n \n \n \n \n NewWave: a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA-seq data.\n \n \n \n\n\n \n Agostinis, F.; Romualdi, C.; Sales, G.; and Risso, D.\n\n\n \n\n\n\n
Bioinformatics, 38(9): 2648–2650. 2022.\n
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@article{agostinis2022newwave,\n title={NewWave: a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA-seq data},\n author={Agostinis, Federico and Romualdi, Chiara and Sales, Gabriele and Risso, Davide},\n journal={Bioinformatics},\n volume={38},\n number={9},\n pages={2648--2650},\n year={2022},\n publisher={Oxford University Press}\n}\n\n\n
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\n\n \n \n \n \n \n Receiver operating characteristic estimation and threshold selection criteria in three-class classification problems for clustered data.\n \n \n \n\n\n \n To, D.; Adimari, G.; Chiogna, M.; and Risso, D.\n\n\n \n\n\n\n
Statistical Methods in Medical Research, 31(7): 1325–1341. 2022.\n
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@article{to2022receiver,\n title={Receiver operating characteristic estimation and threshold selection criteria in three-class classification problems for clustered data},\n author={To, Duc-Khanh and Adimari, Gianfranco and Chiogna, Monica and Risso, Davide},\n journal={Statistical Methods in Medical Research},\n volume={31},\n number={7},\n pages={1325--1341},\n year={2022},\n publisher={SAGE Publications Sage UK: London, England}\n}\n\n\n
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\n \n 2021\n \n \n (7)\n \n \n
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\n\n \n \n \n \n \n mbkmeans: Fast clustering for single cell data using mini-batch k-means.\n \n \n \n\n\n \n Hicks, S. C; Liu, R.; Ni, Y.; Purdom, E.; and Risso, D.\n\n\n \n\n\n\n
PLoS Computational Biology, 17(1): e1008625. 2021.\n
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@article{hicks2021mbkmeans,\n title={mbkmeans: Fast clustering for single cell data using mini-batch k-means},\n author={Hicks, Stephanie C and Liu, Ruoxi and Ni, Yuwei and Purdom, Elizabeth and Risso, Davide},\n journal={PLoS Computational Biology},\n volume={17},\n number={1},\n pages={e1008625},\n year={2021},\n publisher={Public Library of Science San Francisco, CA USA}\n}\n\n\n
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\n\n \n \n \n \n \n Per-sample standardization and asymmetric winsorization lead to accurate clustering of RNA-seq expression profiles.\n \n \n \n\n\n \n Risso, D.; and Pagnotta, S. M.\n\n\n \n\n\n\n
Bioinformatics, 37(16): 2356–2364. 2021.\n
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@article{risso2021per,\n title={Per-sample standardization and asymmetric winsorization lead to accurate clustering of RNA-seq expression profiles},\n author={Risso, Davide and Pagnotta, Stefano Maria},\n journal={Bioinformatics},\n volume={37},\n number={16},\n pages={2356--2364},\n year={2021},\n publisher={Oxford University Press}\n}\n\n\n
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\n\n \n \n \n \n \n A spatially resolved brain region-and cell type-specific isoform atlas of the postnatal mouse brain.\n \n \n \n\n\n \n Joglekar, A.; Prjibelski, A.; Mahfouz, A.; Collier, P.; Lin, S.; Schlusche, A. K.; Marrocco, J.; Williams, S. R; Haase, B.; Hayes, A.; and others\n\n\n \n\n\n\n
Nature Communications, 12(1): 463. 2021.\n
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@article{joglekar2021spatially,\n title={A spatially resolved brain region-and cell type-specific isoform atlas of the postnatal mouse brain},\n author={Joglekar, Anoushka and Prjibelski, Andrey and Mahfouz, Ahmed and Collier, Paul and Lin, Susan and Schlusche, Anna Katharina and Marrocco, Jordan and Williams, Stephen R and Haase, Bettina and Hayes, Ashley and others},\n journal={Nature Communications},\n volume={12},\n number={1},\n pages={463},\n year={2021},\n publisher={Nature Publishing Group UK London}\n}\n\n\n
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\n\n \n \n \n \n \n Normalization of single-cell RNA-seq data.\n \n \n \n\n\n \n Risso, D.\n\n\n \n\n\n\n In
RNA Bioinformatics, pages 303–329. Springer US New York, NY, 2021.\n
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@incollection{risso2021normalization,\n title={Normalization of single-cell RNA-seq data},\n author={Risso, Davide},\n booktitle={RNA Bioinformatics},\n pages={303--329},\n year={2021},\n publisher={Springer US New York, NY}\n}\n\n\n
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\n\n \n \n \n \n \n A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex.\n \n \n \n\n\n \n Yao, Z.; Liu, H.; Xie, F.; Fischer, S.; Adkins, R. S; Aldridge, A. I; Ament, S. A; Bartlett, A.; Behrens, M M.; Van den Berge, K.; and others\n\n\n \n\n\n\n
Nature, 598(7879): 103–110. 2021.\n
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@article{yao2021transcriptomic,\n title={A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex},\n author={Yao, Zizhen and Liu, Hanqing and Xie, Fangming and Fischer, Stephan and Adkins, Ricky S and Aldridge, Andrew I and Ament, Seth A and Bartlett, Anna and Behrens, M Margarita and Van den Berge, Koen and others},\n journal={Nature},\n volume={598},\n number={7879},\n pages={103--110},\n year={2021},\n publisher={Nature Publishing Group UK London}\n}\n\n\n
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\n\n \n \n \n \n \n A multimodal cell census and atlas of the mammalian primary motor cortex.\n \n \n \n\n\n \n (BICCN), B. I. C. C. N.\n\n\n \n\n\n\n
Nature, 598(7879): 86–102. 2021.\n
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@article{brain2021multimodal,\n title={A multimodal cell census and atlas of the mammalian primary motor cortex},\n author={BRAIN Initiative Cell Census Network (BICCN)},\n journal={Nature},\n volume={598},\n number={7879},\n pages={86--102},\n year={2021},\n publisher={Nature Publishing Group UK London}\n}\n\n\n
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\n \n 2020\n \n \n (5)\n \n \n
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\n\n \n \n \n \n \n Orchestrating single-cell analysis with Bioconductor.\n \n \n \n\n\n \n Amezquita, R. A; Lun, A. T.; Becht, E.; Carey, V. J; Carpp, L. N; Geistlinger, L.; Marini, F.; Rue-Albrecht, K.; Risso, D.; Soneson, C.; and others\n\n\n \n\n\n\n
Nature Methods, 17(2): 137–145. 2020.\n
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@article{amezquita2020orchestrating,\n title={Orchestrating single-cell analysis with Bioconductor},\n author={Amezquita, Robert A and Lun, Aaron TL and Becht, Etienne and Carey, Vince J and Carpp, Lindsay N and Geistlinger, Ludwig and Marini, Federico and Rue-Albrecht, Kevin and Risso, Davide and Soneson, Charlotte and others},\n journal={Nature Methods},\n volume={17},\n number={2},\n pages={137--145},\n year={2020},\n publisher={Nature Publishing Group US New York}\n}\n\n\n
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\n\n \n \n \n \n \n Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia.\n \n \n \n\n\n \n Brann, D. H; Tsukahara, T.; Weinreb, C.; Lipovsek, M.; Van den Berge, K.; Gong, B.; Chance, R.; Macaulay, I. C; Chou, H.; Fletcher, R. B; and others\n\n\n \n\n\n\n
Science Advances, 6(31): eabc5801. 2020.\n
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@article{brann2020non,\n title={Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia},\n author={Brann, David H and Tsukahara, Tatsuya and Weinreb, Caleb and Lipovsek, Marcela and Van den Berge, Koen and Gong, Boying and Chance, Rebecca and Macaulay, Iain C and Chou, Hsin-Jung and Fletcher, Russell B and others},\n journal={Science Advances},\n volume={6},\n number={31},\n pages={eabc5801},\n year={2020},\n publisher={American Association for the Advancement of Science}\n}\n\n\n
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\n\n \n \n \n \n \n Multi-omic data integration in oncology.\n \n \n \n\n\n \n Finotello, F.; Calura, E.; Risso, D.; Hautaniemi, S.; and Romualdi, C.\n\n\n \n\n\n\n
Frontiers in Oncology, 10: 1768. 2020.\n
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@article{finotello2020multi,\n title={Multi-omic data integration in oncology},\n author={Finotello, Francesca and Calura, Enrica and Risso, Davide and Hautaniemi, Sampsa and Romualdi, Chiara},\n journal={Frontiers in Oncology},\n volume={10},\n pages={1768},\n year={2020}\n}\n\n\n
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\n \n 2019\n \n \n (4)\n \n \n
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\n\n \n \n \n \n \n Shank3 modulates sleep and expression of circadian transcription factors.\n \n \n \n\n\n \n Ingiosi, A. M; Schoch, H.; Wintler, T.; Singletary, K. G; Righelli, D.; Roser, L. G; Medina, E.; Risso, D.; Frank, M. G; and Peixoto, L.\n\n\n \n\n\n\n
Elife, 8: e42819. 2019.\n
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@article{ingiosi2019shank3,\n title={Shank3 modulates sleep and expression of circadian transcription factors},\n author={Ingiosi, Ashley M and Schoch, Hannah and Wintler, Taylor and Singletary, Kristan G and Righelli, Dario and Roser, Leandro G and Medina, Elizabeth and Risso, Davide and Frank, Marcos G and Peixoto, Lucia},\n journal={Elife},\n volume={8},\n pages={e42819},\n year={2019},\n publisher={eLife Sciences Publications, Ltd}\n}\n\n\n
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\n\n \n \n \n \n \n Complementary networks of cortical somatostatin interneurons enforce layer specific control.\n \n \n \n\n\n \n Naka, A.; Veit, J.; Shababo, B.; Chance, R. K; Risso, D.; Stafford, D.; Snyder, B.; Egladyous, A.; Chu, D.; Sridharan, S.; and others\n\n\n \n\n\n\n
Elife, 8: e43696. 2019.\n
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@article{naka2019complementary,\n title={Complementary networks of cortical somatostatin interneurons enforce layer specific control},\n author={Naka, Alexander and Veit, Julia and Shababo, Ben and Chance, Rebecca K and Risso, Davide and Stafford, David and Snyder, Benjamin and Egladyous, Andrew and Chu, Desiree and Sridharan, Savitha and others},\n journal={Elife},\n volume={8},\n pages={e43696},\n year={2019},\n publisher={eLife Sciences Publications, Ltd}\n}\n\n\n
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\n\n \n \n \n \n \n Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.\n \n \n \n\n\n \n Gaiti, F.; Chaligne, R.; Gu, H.; Brand, R. M; Kothen-Hill, S.; Schulman, R. C; Grigorev, K.; Risso, D.; Kim, K.; Pastore, A.; and others\n\n\n \n\n\n\n
Nature, 569(7757): 576–580. 2019.\n
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@article{gaiti2019epigenetic,\n title={Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia},\n author={Gaiti, Federico and Chaligne, Ronan and Gu, Hongcang and Brand, Ryan M and Kothen-Hill, Steven and Schulman, Rafael C and Grigorev, Kirill and Risso, Davide and Kim, Kyu-Tae and Pastore, Alessandro and others},\n journal={Nature},\n volume={569},\n number={7757},\n pages={576--580},\n year={2019},\n publisher={Nature Publishing Group UK London}\n}\n\n\n
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\n \n 2018\n \n \n (7)\n \n \n
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\n\n \n \n \n \n \n Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics.\n \n \n \n\n\n \n Street, K.; Risso, D.; Fletcher, R. B; Das, D.; Ngai, J.; Yosef, N.; Purdom, E.; and Dudoit, S.\n\n\n \n\n\n\n
BMC Genomics, 19(1): 477. 2018.\n
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@article{street2018slingshot,\n title={Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics},\n author={Street, Kelly and Risso, Davide and Fletcher, Russell B and Das, Diya and Ngai, John and Yosef, Nir and Purdom, Elizabeth and Dudoit, Sandrine},\n journal={BMC Genomics},\n volume={19},\n number={1},\n pages={477},\n year={2018},\n publisher={BioMed Central London}\n}\n\n\n
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\n\n \n \n \n \n \n Learning-dependent chromatin remodeling highlights noncoding regulatory regions linked to autism.\n \n \n \n\n\n \n Koberstein, J. N; Poplawski, S. G; Wimmer, M. E; Porcari, G.; Kao, C.; Gomes, B.; Risso, D.; Hakonarson, H.; Zhang, N. R; Schultz, R. T; and others\n\n\n \n\n\n\n
Science Signaling, 11(513): eaan6500. 2018.\n
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@article{koberstein2018learning,\n title={Learning-dependent chromatin remodeling highlights noncoding regulatory regions linked to autism},\n author={Koberstein, John N and Poplawski, Shane G and Wimmer, Mathieu E and Porcari, Giulia and Kao, Charlly and Gomes, Bruce and Risso, Davide and Hakonarson, Hakon and Zhang, Nancy R and Schultz, Robert T and others},\n journal={Science Signaling},\n volume={11},\n number={513},\n pages={eaan6500},\n year={2018},\n publisher={American Association for the Advancement of Science}\n}\n\n\n
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\n\n \n \n \n \n \n A general and flexible method for signal extraction from single-cell RNA-seq data.\n \n \n \n\n\n \n Risso, D.; Perraudeau, F.; Gribkova, S.; Dudoit, S.; and Vert, J.\n\n\n \n\n\n\n
Nature Communications, 9(1): 284. 2018.\n
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@article{risso2018general,\n title={A general and flexible method for signal extraction from single-cell RNA-seq data},\n author={Risso, Davide and Perraudeau, Fanny and Gribkova, Svetlana and Dudoit, Sandrine and Vert, Jean-Philippe},\n journal={Nature Communications},\n volume={9},\n number={1},\n pages={284},\n year={2018},\n publisher={Nature Publishing Group UK London}\n}\n\n\n
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\n\n \n \n \n \n \n clusterExperiment and RSEC: A Bioconductor package and framework for clustering of single-cell and other large gene expression datasets.\n \n \n \n\n\n \n Risso, D.; Purvis, L.; Fletcher, R. B; Das, D.; Ngai, J.; Dudoit, S.; and Purdom, E.\n\n\n \n\n\n\n
PLoS Computational Biology, 14(9): e1006378. 2018.\n
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@article{risso2018clusterexperiment,\n title={clusterExperiment and RSEC: A Bioconductor package and framework for clustering of single-cell and other large gene expression datasets},\n author={Risso, Davide and Purvis, Liam and Fletcher, Russell B and Das, Diya and Ngai, John and Dudoit, Sandrine and Purdom, Elizabeth},\n journal={PLoS Computational Biology},\n volume={14},\n number={9},\n pages={e1006378},\n year={2018},\n publisher={Public Library of Science}\n}\n\n\n
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\n\n \n \n \n \n \n Combinatorial expression of Grp and Neurod6 defines dopamine neuron populations with distinct projection patterns and disease vulnerability.\n \n \n \n\n\n \n Kramer, D. J; Risso, D.; Kosillo, P.; Ngai, J.; and Bateup, H. S\n\n\n \n\n\n\n
eNeuro, 5(3). 2018.\n
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@article{kramer2018combinatorial,\n title={Combinatorial expression of Grp and Neurod6 defines dopamine neuron populations with distinct projection patterns and disease vulnerability},\n author={Kramer, Daniel J and Risso, Davide and Kosillo, Polina and Ngai, John and Bateup, Helen S},\n journal={eNeuro},\n volume={5},\n number={3},\n year={2018},\n publisher={Society for Neuroscience}\n}\n\n\n
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\n\n \n \n \n \n \n Differential Enriched Scan 2 (DEScan2): a fast pipeline for broad peak analysis.\n \n \n \n\n\n \n Righelli, D.; Koberstein, J.; Zhang, N.; Angelini, C.; Peixoto, L.; and Risso, D.\n\n\n \n\n\n\n Technical Report PeerJ Preprints, 2018.\n
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@techreport{righelli2018differential,\n title={Differential Enriched Scan 2 (DEScan2): a fast pipeline for broad peak analysis},\n author={Righelli, Dario and Koberstein, John and Zhang, Nancy and Angelini, Claudia and Peixoto, Lucia and Risso, Davide},\n year={2018},\n institution={PeerJ Preprints}\n}\n\n\n
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\n \n 2017\n \n \n (5)\n \n \n
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\n\n \n \n \n \n \n Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells.\n \n \n \n\n\n \n Choi, Y. J.; Lin, C.; Risso, D.; Chen, S.; Kim, T. A.; Tan, M. H.; Li, J. B.; Wu, Y.; Chen, C.; Xuan, Z.; and others\n\n\n \n\n\n\n
Science, 355(6325): eaag1927. 2017.\n
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@article{choi2017deficiency,\n title={Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells},\n author={Choi, Yong Jin and Lin, Chao-Po and Risso, Davide and Chen, Sean and Kim, Thomas Aquinas and Tan, Meng How and Li, Jin Billy and Wu, Yalei and Chen, Caifu and Xuan, Zhenyu and others},\n journal={Science},\n volume={355},\n number={6325},\n pages={eaag1927},\n year={2017},\n publisher={American Association for the Advancement of Science}\n}\n\n\n
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\n\n \n \n \n \n \n Deconstructing olfactory stem cell trajectories at single-cell resolution.\n \n \n \n\n\n \n Fletcher, R. B; Das, D.; Gadye, L.; Street, K. N; Baudhuin, A.; Wagner, A.; Cole, M. B; Flores, Q.; Choi, Y. G.; Yosef, N.; and others\n\n\n \n\n\n\n
Cell Stem Cell, 20(6): 817–830. 2017.\n
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@article{fletcher2017deconstructing,\n title={Deconstructing olfactory stem cell trajectories at single-cell resolution},\n author={Fletcher, Russell B and Das, Diya and Gadye, Levi and Street, Kelly N and Baudhuin, Ariane and Wagner, Allon and Cole, Michael B and Flores, Quetzal and Choi, Yoon Gi and Yosef, Nir and others},\n journal={Cell Stem Cell},\n volume={20},\n number={6},\n pages={817--830},\n year={2017},\n publisher={Elsevier}\n}\n\n\n
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\n\n \n \n \n \n \n Normalizing single-cell RNA sequencing data: challenges and opportunities.\n \n \n \n\n\n \n Vallejos, C. A; Risso, D.; Scialdone, A.; Dudoit, S.; and Marioni, J. C\n\n\n \n\n\n\n
Nature Methods, 14(6): 565–571. 2017.\n
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@article{vallejos2017normalizing,\n title={Normalizing single-cell RNA sequencing data: challenges and opportunities},\n author={Vallejos, Catalina A and Risso, Davide and Scialdone, Antonio and Dudoit, Sandrine and Marioni, John C},\n journal={Nature Methods},\n volume={14},\n number={6},\n pages={565--571},\n year={2017},\n publisher={Nature Publishing Group US New York}\n}\n\n\n
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\n\n \n \n \n \n \n Bioconductor workflow for single-cell RNA sequencing: Normalization, dimensionality reduction, clustering, and lineage inference.\n \n \n \n\n\n \n Perraudeau, F.; Risso, D.; Street, K.; Purdom, E.; and Dudoit, S.\n\n\n \n\n\n\n
F1000Research, 6: 1158. 2017.\n
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\n
@article{perraudeau2017bioconductor,\n title={Bioconductor workflow for single-cell RNA sequencing: Normalization, dimensionality reduction, clustering, and lineage inference},\n author={Perraudeau, Fanny and Risso, Davide and Street, Kelly and Purdom, Elizabeth and Dudoit, Sandrine},\n journal={F1000Research},\n volume={6},\n pages={1158},\n year={2017}\n}\n\n\n
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\n\n \n \n \n \n \n Injury activates transient olfactory stem cell states with diverse lineage capacities.\n \n \n \n\n\n \n Gadye, L.; Das, D.; Sanchez, M. A; Street, K.; Baudhuin, A.; Wagner, A.; Cole, M. B; Choi, Y. G.; Yosef, N.; Purdom, E.; and others\n\n\n \n\n\n\n
Cell Stem Cell, 21(6): 775–790. 2017.\n
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@article{gadye2017injury,\n title={Injury activates transient olfactory stem cell states with diverse lineage capacities},\n author={Gadye, Levi and Das, Diya and Sanchez, Michael A and Street, Kelly and Baudhuin, Ariane and Wagner, Allon and Cole, Michael B and Choi, Yoon Gi and Yosef, Nir and Purdom, Elizabeth and others},\n journal={Cell Stem Cell},\n volume={21},\n number={6},\n pages={775--790},\n year={2017},\n publisher={Elsevier}\n}\n\n\n
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\n \n 2016\n \n \n (3)\n \n \n
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\n\n \n \n \n \n \n Comparison of computed tomography and magnetic resonance imaging in the discrimination of intraperitoneal and extraperitoneal rectal cancer: initial experience.\n \n \n \n\n\n \n Revelli, M.; Paparo, F.; Bacigalupo, L.; Puppo, C.; Furnari, M.; Conforti, C.; Binda, G. A.; Savarino, E.; Risso, D.; and Rollandi, G. A.\n\n\n \n\n\n\n
Clinical Imaging, 40(1): 57–62. 2016.\n
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@article{revelli2016comparison,\n title={Comparison of computed tomography and magnetic resonance imaging in the discrimination of intraperitoneal and extraperitoneal rectal cancer: initial experience},\n author={Revelli, Matteo and Paparo, Francesco and Bacigalupo, Lorenzo and Puppo, Cristina and Furnari, Manuele and Conforti, Cristina and Binda, Gian Andrea and Savarino, Edoardo and Risso, Davide and Rollandi, Gian Andrea},\n journal={Clinical Imaging},\n volume={40},\n number={1},\n pages={57--62},\n year={2016},\n publisher={Elsevier}\n}\n\n\n
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\n\n \n \n \n \n \n Contextual fear conditioning induces differential alternative splicing.\n \n \n \n\n\n \n Poplawski, S. G; Peixoto, L.; Porcari, G. S; Wimmer, M. E; McNally, A. G; Mizuno, K.; Giese, K P.; Chatterjee, S.; Koberstein, J. N; Risso, D.; and others\n\n\n \n\n\n\n
Neurobiology of Learning and Memory, 134: 221–235. 2016.\n
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@article{poplawski2016contextual,\n title={Contextual fear conditioning induces differential alternative splicing},\n author={Poplawski, Shane G and Peixoto, Lucia and Porcari, Giulia S and Wimmer, Mathieu E and McNally, Anna G and Mizuno, Keiko and Giese, K Peter and Chatterjee, Snehajyoti and Koberstein, John N and Risso, Davide and others},\n journal={Neurobiology of Learning and Memory},\n volume={134},\n pages={221--235},\n year={2016},\n publisher={Academic Press}\n}\n\n\n
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\n\n \n \n \n \n \n Removal of unwanted variation reveals novel patterns of gene expression linked to sleep homeostasis in murine cortex.\n \n \n \n\n\n \n Gerstner, J. R; Koberstein, J. N; Watson, A. J; Zapero, N.; Risso, D.; Speed, T. P; Frank, M. G; and Peixoto, L.\n\n\n \n\n\n\n
BMC Genomics, 17(Suppl 8): 727. 2016.\n
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@article{gerstner2016removal,\n title={Removal of unwanted variation reveals novel patterns of gene expression linked to sleep homeostasis in murine cortex},\n author={Gerstner, Jason R and Koberstein, John N and Watson, Adam J and Zapero, Nikolai and Risso, Davide and Speed, Terence P and Frank, Marcos G and Peixoto, Lucia},\n journal={BMC Genomics},\n volume={17},\n number={Suppl 8},\n pages={727},\n year={2016},\n publisher={BioMed Central London}\n}\n\n\n
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\n \n 2015\n \n \n (1)\n \n \n
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\n\n \n \n \n \n \n How data analysis affects power, reproducibility and biological insight of RNA-seq studies in complex datasets.\n \n \n \n\n\n \n Peixoto, L.; Risso, D.; Poplawski, S. G; Wimmer, M. E; Speed, T. P; Wood, M. A; and Abel, T.\n\n\n \n\n\n\n
Nucleic Acids Research, 43(16): 7664–7674. 2015.\n
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@article{peixoto2015data,\n title={How data analysis affects power, reproducibility and biological insight of RNA-seq studies in complex datasets},\n author={Peixoto, Lucia and Risso, Davide and Poplawski, Shane G and Wimmer, Mathieu E and Speed, Terence P and Wood, Marcelo A and Abel, Ted},\n journal={Nucleic Acids Research},\n volume={43},\n number={16},\n pages={7664--7674},\n year={2015},\n publisher={Oxford University Press}\n}\n\n\n
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\n \n 2014\n \n \n (3)\n \n \n
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\n\n \n \n \n \n \n Silencing of odorant receptor genes by G protein $β$$γ$ signaling ensures the expression of one odorant receptor per olfactory sensory neuron.\n \n \n \n\n\n \n Ferreira, T.; Wilson, S. R; Choi, Y. G.; Risso, D.; Dudoit, S.; Speed, T. P; and Ngai, J.\n\n\n \n\n\n\n
Neuron, 81(4): 847–859. 2014.\n
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@article{ferreira2014silencing,\n title={Silencing of odorant receptor genes by G protein $\\beta$$\\gamma$ signaling ensures the expression of one odorant receptor per olfactory sensory neuron},\n author={Ferreira, Todd and Wilson, Sarah R and Choi, Yoon Gi and Risso, Davide and Dudoit, Sandrine and Speed, Terence P and Ngai, John},\n journal={Neuron},\n volume={81},\n number={4},\n pages={847--859},\n year={2014},\n publisher={Elsevier}\n}\n\n\n
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\n\n \n \n \n \n \n The role of spike-in standards in the normalization of RNA-seq.\n \n \n \n\n\n \n Risso, D.; Ngai, J.; Speed, T. P; and Dudoit, S.\n\n\n \n\n\n\n In
Statistical Analysis of Next Generation Sequencing Data, pages 169–190. Springer International Publishing Cham, 2014.\n
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@incollection{risso2014role,\n title={The role of spike-in standards in the normalization of RNA-seq},\n author={Risso, Davide and Ngai, John and Speed, Terence P and Dudoit, Sandrine},\n booktitle={Statistical Analysis of Next Generation Sequencing Data},\n pages={169--190},\n year={2014},\n publisher={Springer International Publishing Cham}\n}\n\n\n
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\n\n \n \n \n \n \n Normalization of RNA-seq data using factor analysis of control genes or samples.\n \n \n \n\n\n \n Risso, D.; Ngai, J.; Speed, T. P; and Dudoit, S.\n\n\n \n\n\n\n
Nature Biotechnology, 32(9): 896–902. 2014.\n
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\n
@article{risso2014normalization,\n title={Normalization of RNA-seq data using factor analysis of control genes or samples},\n author={Risso, Davide and Ngai, John and Speed, Terence P and Dudoit, Sandrine},\n journal={Nature Biotechnology},\n volume={32},\n number={9},\n pages={896--902},\n year={2014},\n publisher={Nature Publishing Group}\n}\n\n\n
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\n\n
\n
\n \n 2012\n \n \n (1)\n \n \n
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\n\n \n \n \n \n \n A hierarchical Bayesian model for RNA-Seq data.\n \n \n \n\n\n \n Risso, D.; Sales, G.; Romualdi, C.; and Chiogna, M.\n\n\n \n\n\n\n In
Complex Models and Computational Methods in Statistics, pages 215–227. Springer Milan Milano, 2012.\n
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\n
@incollection{risso2012hierarchical,\n title={A hierarchical Bayesian model for RNA-Seq data},\n author={Risso, Davide and Sales, Gabriele and Romualdi, Chiara and Chiogna, Monica},\n booktitle={Complex Models and Computational Methods in Statistics},\n pages={215--227},\n year={2012},\n publisher={Springer Milan Milano}\n}\n\n\n
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\n \n 2011\n \n \n (3)\n \n \n
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\n\n \n \n \n \n \n A novel approach to the clustering of microarray data via nonparametric density estimation.\n \n \n \n\n\n \n De Bin, R.; and Risso, D.\n\n\n \n\n\n\n
BMC Bioinformatics, 12(1): 49. 2011.\n
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\n
@article{de2011novel,\n title={A novel approach to the clustering of microarray data via nonparametric density estimation},\n author={De Bin, Riccardo and Risso, Davide},\n journal={BMC Bioinformatics},\n volume={12},\n number={1},\n pages={49},\n year={2011},\n publisher={BioMed Central Ltd}\n}\n\n\n
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\n\n \n \n \n \n \n GC-content normalization for RNA-Seq data.\n \n \n \n\n\n \n Risso, D.; Schwartz, K.; Sherlock, G.; and Dudoit, S.\n\n\n \n\n\n\n
BMC Bioinformatics, 12(1): 480. 2011.\n
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@article{risso2011gc,\n title={GC-content normalization for RNA-Seq data},\n author={Risso, Davide and Schwartz, Katja and Sherlock, Gavin and Dudoit, Sandrine},\n journal={BMC Bioinformatics},\n volume={12},\n number={1},\n pages={480},\n year={2011},\n publisher={BioMed Central London}\n}\n\n\n
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\n \n 2009\n \n \n (3)\n \n \n
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\n\n \n \n \n \n \n A comparison on effects of normalisations in the detection of differentially expressed genes.\n \n \n \n\n\n \n Chiogna, M.; Massa, M. S.; Risso, D.; and Romualdi, C.\n\n\n \n\n\n\n
BMC Bioinformatics, 10(1): 61. 2009.\n
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@article{chiogna2009comparison,\n title={A comparison on effects of normalisations in the detection of differentially expressed genes},\n author={Chiogna, Monica and Massa, Maria Sofia and Risso, Davide and Romualdi, Chiara},\n journal={BMC Bioinformatics},\n volume={10},\n number={1},\n pages={61},\n year={2009},\n publisher={BioMed Central London}\n}\n\n\n
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\n\n \n \n \n \n \n A modified LOESS normalization applied to microRNA arrays: a comparative evaluation.\n \n \n \n\n\n \n Risso, D.; Massa, M. S.; Chiogna, M.; and Romualdi, C.\n\n\n \n\n\n\n
Bioinformatics, 25(20): 2685–2691. 2009.\n
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@article{risso2009modified,\n title={A modified LOESS normalization applied to microRNA arrays: a comparative evaluation},\n author={Risso, Davide and Massa, Maria Sofia and Chiogna, Monica and Romualdi, Chiara},\n journal={Bioinformatics},\n volume={25},\n number={20},\n pages={2685--2691},\n year={2009},\n publisher={Oxford University Press}\n}\n\n\n
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