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\n\n \n \n \n \n \n \n Zn(II) ion modulated red emitting copper nanocluster probe for the fluorescence turn on sensing of RDX.\n \n \n \n \n\n\n \n Aparna, R. S.; Anjali Devi, J. S.; Anjana, R. R; Nebu, J.; and George, S.\n\n\n \n\n\n\n
Sensors and Actuators B: Chemical, 291: 298–305. July 2019.\n
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@article{aparna_znii_2019,\n\ttitle = {Zn({II}) ion modulated red emitting copper nanocluster probe for the fluorescence turn on sensing of {RDX}},\n\tvolume = {291},\n\tissn = {0925-4005},\n\turl = {https://www.sciencedirect.com/science/article/pii/S092540051930574X},\n\tdoi = {10.1016/j.snb.2019.04.051},\n\tabstract = {Field employed detection of hidden explosives has drawn intense attention as it poses significant threat to public safety and security. Among the explosives, the selective detection of heterocyclic nitramine compounds such as 1,3,5-trinitrotriazine (RDX) is still challenging since it lacks nitroaromatic rings, possess higher LUMO energies and even lower vapour pressure. In the present work, water soluble BSA stabilized copper nanocluster is synthesized by using sodium borohydride as reducing agent. The resultant nanocluster having size less than 3 nm showed intense red emission at 650 nm upon excitation at 440 nm. Fluorescence of the BSA stabilized copper nanocluster is effectively quenched by the addition of Zn(II) ion and the quenching is attributed to photoinduced electron transfer followed by aggregation. The limit of detection for Zn(II) ion is obtained as 15 nM and is much lower than that of the World Health organization permitted level of Zn(II) ion in drinking water which is 76 μM. The fast recovery of the fluorescence is observed after addition of RDX to the quenched system which is attributed to the high affinity of Zn(II) ion with RDX. The limit of detection for RDX sensing is obtained at 1.62 nM. Additionally, a straight forward fluorescent paper strip sensor is developed to detect both Zn(II) and RDX, providing an onsite detecting platform for both homeland and environmental security.},\n\turldate = {2024-10-15},\n\tjournal = {Sensors and Actuators B: Chemical},\n\tauthor = {Aparna, R. S. and Anjali Devi, J. S. and Anjana, R. R and Nebu, John and George, Sony},\n\tmonth = jul,\n\tyear = {2019},\n\tkeywords = {1, 3, 5-Trinitrotriazine (RDX), BSA, Copper nanocluster, Explosives, Fluorescence sensor, Paper strip detection},\n\tpages = {298--305},\n}\n\n\n\n
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\n Field employed detection of hidden explosives has drawn intense attention as it poses significant threat to public safety and security. Among the explosives, the selective detection of heterocyclic nitramine compounds such as 1,3,5-trinitrotriazine (RDX) is still challenging since it lacks nitroaromatic rings, possess higher LUMO energies and even lower vapour pressure. In the present work, water soluble BSA stabilized copper nanocluster is synthesized by using sodium borohydride as reducing agent. The resultant nanocluster having size less than 3 nm showed intense red emission at 650 nm upon excitation at 440 nm. Fluorescence of the BSA stabilized copper nanocluster is effectively quenched by the addition of Zn(II) ion and the quenching is attributed to photoinduced electron transfer followed by aggregation. The limit of detection for Zn(II) ion is obtained as 15 nM and is much lower than that of the World Health organization permitted level of Zn(II) ion in drinking water which is 76 μM. The fast recovery of the fluorescence is observed after addition of RDX to the quenched system which is attributed to the high affinity of Zn(II) ion with RDX. The limit of detection for RDX sensing is obtained at 1.62 nM. Additionally, a straight forward fluorescent paper strip sensor is developed to detect both Zn(II) and RDX, providing an onsite detecting platform for both homeland and environmental security.\n
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\n\n \n \n \n \n \n \n Vulcanization kinetics and mechanical properties of organically modified nanoclay incorporated natural and chlorobutyl rubber nanocomposites.\n \n \n \n \n\n\n \n Zachariah, A. K.; Chandra, A. K.; Mohammed, P. K.; and Thomas, S.\n\n\n \n\n\n\n
Polymer Testing, 76: 154–165. July 2019.\n
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@article{zachariah_vulcanization_2019,\n\ttitle = {Vulcanization kinetics and mechanical properties of organically modified nanoclay incorporated natural and chlorobutyl rubber nanocomposites},\n\tvolume = {76},\n\tissn = {0142-9418},\n\turl = {https://www.sciencedirect.com/science/article/pii/S014294181831849X},\n\tdoi = {10.1016/j.polymertesting.2019.02.003},\n\tabstract = {The curing kinetics, vulcanizate properties, mechanical reinforcement and chemical interactions of organically modified nanoclay filled natural rubber (NR) and chlorobutyl (CIIR) rubbers have been studied. From the vulcanization studies, it is observed that nanoclays are more intercalated in NR matrix rather than CIIR matrix. To understand the exact mechanism operating in the vulcanization behavior of NR and CIIR, autocatalytic model was applied. The vulcanization kinetic studies revealed that the nanoclay distribution at high temperature (190 °C) in CIIR matrix is somewhat intercalated in nature. Highly pronounced reversion behavior was observed in NR matrix. The mechanical reinforcement of vulcanizates was examined using the change in modulus values at 100\\% and 300\\% elongation. The mechanical properties were modeled using different kind of models such as Guth-Smallwood, Halpin-Tsai, modified Halpin-Tsai and Mori-Tanaka models. Finally, the dispersion of nanoclay platelets in CIIR and NR matrix was confirmed by the phase images obtained from AFM technique.},\n\turldate = {2024-10-16},\n\tjournal = {Polymer Testing},\n\tauthor = {Zachariah, Ajesh K. and Chandra, Arup Kumar and Mohammed, P. K. and Thomas, Sabu},\n\tmonth = jul,\n\tyear = {2019},\n\tkeywords = {Chlorobutyl rubber, Mechanical modeling, Nanocomposites, Natural rubber, Vulcanization kinetics},\n\tpages = {154--165},\n}\n\n\n\n\n\n\n\n\n\n\n\n
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\n The curing kinetics, vulcanizate properties, mechanical reinforcement and chemical interactions of organically modified nanoclay filled natural rubber (NR) and chlorobutyl (CIIR) rubbers have been studied. From the vulcanization studies, it is observed that nanoclays are more intercalated in NR matrix rather than CIIR matrix. To understand the exact mechanism operating in the vulcanization behavior of NR and CIIR, autocatalytic model was applied. The vulcanization kinetic studies revealed that the nanoclay distribution at high temperature (190 °C) in CIIR matrix is somewhat intercalated in nature. Highly pronounced reversion behavior was observed in NR matrix. The mechanical reinforcement of vulcanizates was examined using the change in modulus values at 100% and 300% elongation. The mechanical properties were modeled using different kind of models such as Guth-Smallwood, Halpin-Tsai, modified Halpin-Tsai and Mori-Tanaka models. Finally, the dispersion of nanoclay platelets in CIIR and NR matrix was confirmed by the phase images obtained from AFM technique.\n
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\n\n \n \n \n \n \n \n Understanding the Citric Acid–Urea Co–Directed Microwave Assisted Synthesis and Ferric Ion Modulation of Fluorescent Nitrogen Doped Carbon Dots: A Turn On Assay for Ascorbic Acid.\n \n \n \n \n\n\n \n Devi, J. S. A.; Aparna, R. S.; Aswathy, B.; Nebu, J.; Aswathy, A. O.; and George, S.\n\n\n \n\n\n\n
ChemistrySelect, 4(3): 816–824. January 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
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@article{devi_understanding_2019,\n\ttitle = {Understanding the {Citric} {Acid}–{Urea} {Co}–{Directed} {Microwave} {Assisted} {Synthesis} and {Ferric} {Ion} {Modulation} of {Fluorescent} {Nitrogen} {Doped} {Carbon} {Dots}: {A} {Turn} {On} {Assay} for {Ascorbic} {Acid}},\n\tvolume = {4},\n\tissn = {2365-6549},\n\tshorttitle = {Understanding the {Citric} {Acid}–{Urea} {Co}–{Directed} {Microwave} {Assisted} {Synthesis} and {Ferric} {Ion} {Modulation} of {Fluorescent} {Nitrogen} {Doped} {Carbon} {Dots}},\n\turl = {https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.201803726},\n\tdoi = {10.1002/slct.201803726},\n\tabstract = {Abstract Herein, nitrogen doped carbon dots (NCDs) were synthesised from citric acid and urea via a previously reported microwave assisted route. The NCDs shows emission maximum at 500?nm on excitation at 400?nm. The fluorescence of NCDs decreases slightly with increase in basicity of solution up to pH?7.5 and then increases again after pH?8.5, along with a blue-shift in tested alkaline pH. This pH dependent blue-shift indicates the presence of both carboxyl?carboxylate and phenol?phenolate prototropic equilibrium in NCDs. Due to the special interaction of these phenolates and carboxylates on NCDs surface with di- or tri- valent heavy transition metal ions; it is demonstrated that ferric ion (Fe3+ ion) can quench the fluorescence of NCDs. This Fe3+ induced static quenching of NCDs is a collaborative effect of inner filter effect, aggregation and ferromagnetism. However, Ascorbic acid (AA) can recover the fluorescence of Fe3+ quenched NCD with detection limit as low as 96??M. This detection strategy has good selectivity towards AA over other antioxidants, saccharides, proteins and neurotransmitters. Furthermore, (spiked) human serum and (spiked) human urine were analysed and found good recovery percentage.},\n\tnumber = {3},\n\turldate = {2024-10-16},\n\tjournal = {ChemistrySelect},\n\tauthor = {Devi, J. S. Anjali and Aparna, R. S. and Aswathy, B. and Nebu, John and Aswathy, A. O. and George, Sony},\n\tmonth = jan,\n\tyear = {2019},\n\tkeywords = {Ascorbic Acid, Biosensor, Carbon Dots, Fluorescence, Inner Filter Effect, Iron(III)},\n\tpages = {816--824},\n}\n\n\n\n
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\n Abstract Herein, nitrogen doped carbon dots (NCDs) were synthesised from citric acid and urea via a previously reported microwave assisted route. The NCDs shows emission maximum at 500?nm on excitation at 400?nm. The fluorescence of NCDs decreases slightly with increase in basicity of solution up to pH?7.5 and then increases again after pH?8.5, along with a blue-shift in tested alkaline pH. This pH dependent blue-shift indicates the presence of both carboxyl?carboxylate and phenol?phenolate prototropic equilibrium in NCDs. Due to the special interaction of these phenolates and carboxylates on NCDs surface with di- or tri- valent heavy transition metal ions; it is demonstrated that ferric ion (Fe3+ ion) can quench the fluorescence of NCDs. This Fe3+ induced static quenching of NCDs is a collaborative effect of inner filter effect, aggregation and ferromagnetism. However, Ascorbic acid (AA) can recover the fluorescence of Fe3+ quenched NCD with detection limit as low as 96??M. This detection strategy has good selectivity towards AA over other antioxidants, saccharides, proteins and neurotransmitters. Furthermore, (spiked) human serum and (spiked) human urine were analysed and found good recovery percentage.\n
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\n\n \n \n \n \n \n \n Trace level determination of Hg2+ ions in environmental samples with a mercaptotriazole-functionalized TiO2 nanostructure-based fluorescent probe.\n \n \n \n \n\n\n \n B, A. K.; G, R.; Sasitharan, K.; P, V. T.; Varghese, A.; and George, L.\n\n\n \n\n\n\n
Analytical Methods, 11(4): 537–547. January 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
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@article{b_trace_2019,\n\ttitle = {Trace level determination of {Hg2}+ ions in environmental samples with a mercaptotriazole-functionalized {TiO2} nanostructure-based fluorescent probe},\n\tvolume = {11},\n\tissn = {1759-9679},\n\turl = {https://pubs.rsc.org/en/content/articlelanding/2019/ay/c8ay02109k},\n\tdoi = {10.1039/C8AY02109K},\n\tabstract = {A highly selective and sensitive fluorescent probe for the determination of Hg2+ ions is reported using substituted mercaptotriazole functionalized TiO2 nanoparticles (MMT@TiO2). The functionalized TiO2 nanoparticles were characterized by UV-vis spectrophotometric, spectrofluorometric, FT-IR, FT-Raman, XPS, TEM, SEM, EDAX and P-XRD analyses. The interaction of Hg2+ ions with functionalized MMT@TiO2 induced aggregation of nanoparticles causing chelation enhanced fluorescence. The limit of detection and limit of quantitation for the determination of Hg2+ ions were found to be 2.18 × 10−10 M and 6.61 × 10−10 M, respectively. The method developed was successfully applied for the determination of Hg2+ ions in environmental samples.},\n\tlanguage = {en},\n\tnumber = {4},\n\turldate = {2024-10-16},\n\tjournal = {Analytical Methods},\n\tauthor = {B, Akshaya K. and G, Reenamole and Sasitharan, Kezia and P, Vinod T. and Varghese, Anitha and George, Louis},\n\tmonth = jan,\n\tyear = {2019},\n\tpages = {537--547},\n}\n\n\n\n
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\n A highly selective and sensitive fluorescent probe for the determination of Hg2+ ions is reported using substituted mercaptotriazole functionalized TiO2 nanoparticles (MMT@TiO2). The functionalized TiO2 nanoparticles were characterized by UV-vis spectrophotometric, spectrofluorometric, FT-IR, FT-Raman, XPS, TEM, SEM, EDAX and P-XRD analyses. The interaction of Hg2+ ions with functionalized MMT@TiO2 induced aggregation of nanoparticles causing chelation enhanced fluorescence. The limit of detection and limit of quantitation for the determination of Hg2+ ions were found to be 2.18 × 10−10 M and 6.61 × 10−10 M, respectively. The method developed was successfully applied for the determination of Hg2+ ions in environmental samples.\n
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\n\n \n \n \n \n \n \n The lichen genus Pyxine (Caliciaceae) in Kerala state with P. dactyloschmidtii as new to India.\n \n \n \n \n\n\n \n Zachariah, S.; Nayaka, S.; Gupta, P.; and Kadookunnel, S.\n\n\n \n\n\n\n
Hattoria, 10: 109–117. January 2019.\n
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@article{zachariah_lichen_2019,\n\ttitle = {The lichen genus {Pyxine} ({Caliciaceae}) in {Kerala} state with {P}. dactyloschmidtii as new to {India}},\n\tvolume = {10},\n\tissn = {Online ISSN : 2423-8961, Print ISSN : 2185-8241, ISSN-L : 2185-8241},\n\turl = {https://www.jstage.jst.go.jp/article/hattoria/10/0/10_109/_pdf/-char/ja},\n\tabstract = {A total of 12 species of Pyxine is reported from Kerala state of which P. retirugella Nyl. is new to the region while P. dactyloschmidtii Kalb \\& Mongkolsuk is new to India. Pyxine dactyloschmidtii is characterized in having polysidiangia and earlier known from Thailand. Brief descriptions for the novel taxa and a key to all Pyxine species occurring in India are provided.},\n\tlanguage = {English},\n\tjournal = {Hattoria},\n\tauthor = {Zachariah, Sonia and Nayaka, Sanjeeva and Gupta, Pooja and Kadookunnel, Scaria},\n\tmonth = jan,\n\tyear = {2019},\n\tpages = {109--117},\n}\n\n\n\n
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\n A total of 12 species of Pyxine is reported from Kerala state of which P. retirugella Nyl. is new to the region while P. dactyloschmidtii Kalb & Mongkolsuk is new to India. Pyxine dactyloschmidtii is characterized in having polysidiangia and earlier known from Thailand. Brief descriptions for the novel taxa and a key to all Pyxine species occurring in India are provided.\n
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\n\n \n \n \n \n \n \n Synthesis and characterization of a new aroylhydrazone ligand and its cobalt(III) complexes: X-ray crystallography and in vitro evaluation of antibacterial and antifungal activities.\n \n \n \n \n\n\n \n Mathews, N. A.; Jose, A.; and Kurup, M. R. P.\n\n\n \n\n\n\n
Journal of Molecular Structure, 1178: 544–553. February 2019.\n
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@article{mathews_synthesis_2019,\n\ttitle = {Synthesis and characterization of a new aroylhydrazone ligand and its cobalt({III}) complexes: {X}-ray crystallography and \\textit{in vitro} evaluation of antibacterial and antifungal activities},\n\tvolume = {1178},\n\tissn = {0022-2860},\n\tshorttitle = {Synthesis and characterization of a new aroylhydrazone ligand and its cobalt({III}) complexes},\n\turl = {https://www.sciencedirect.com/science/article/pii/S0022286018312560},\n\tdoi = {10.1016/j.molstruc.2018.10.061},\n\tabstract = {A new aroylhydrazone ligand, 2-benzoylpyridine-4-methoxybenzhydrazone (BPMBH) and its two cobalt(III) complexes, [Co(BPMB)2]NO3·1.5H2O (1) and [Co(BPMB)2]Cl·2H2O (2) have been synthesized and structurally characterized. The synthesized compounds are physico-chemically characterized by CHN analysis, molar conductivity, magnetic susceptibility measurements and spectroscopic techniques like MS, IR, UV and NMR. The high molar conductivity values of the complexes confirmed the presence of counter ions in the lattice of the cationic complexes. The molecular structure of the aroylhydrazone and its complexes have been resolved using single crystal XRD studies. In the solid state, the aroylhydrazone exists in the amido form as evident from the IR and XRD studies. The tridentate nature of the NNO donor aroylhydrazone was also confirmed from the IR spectral studies. XRD studies reveal that in all complexes, the tridentate aroylhydrazone coordinates to the Co(III) center via pyridine nitrogen, azomethine nitrogen and iminolate oxygen and found to possess distorted octahedral geometry. The complexes are bis-ligated cationic complexes in which chloride and nitrate ions act as counter ions. The antibacterial and antifungal activities of the aroylhydrazone and its Co(III) complexes have been screened against bacterial species Staphylococcus aureus, Enterobacter aerogenes, Bacillus subtilis, Streptococcus pyogenes, Klebsiella pneumonia, Salmonella typhi and Escherichia coli. The antifungal activity was also checked using fungi Aspergillus niger, Penicillium chrysogenum and Rhizopus oryzae. From the activity data we can infer that the metal complexes have better biological activity than the metal free ligand against the bacterial and fungal species which were tested.},\n\turldate = {2024-10-16},\n\tjournal = {Journal of Molecular Structure},\n\tauthor = {Mathews, Nimya Ann and Jose, Anitha and Kurup, M. R. Prathapachandra},\n\tmonth = feb,\n\tyear = {2019},\n\tkeywords = {Aroylhydrazone, Biological activity, Cobalt(III) complexes, Crystal structures, IR spectra},\n\tpages = {544--553},\n}\n\n\n\n
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\n A new aroylhydrazone ligand, 2-benzoylpyridine-4-methoxybenzhydrazone (BPMBH) and its two cobalt(III) complexes, [Co(BPMB)2]NO3·1.5H2O (1) and [Co(BPMB)2]Cl·2H2O (2) have been synthesized and structurally characterized. The synthesized compounds are physico-chemically characterized by CHN analysis, molar conductivity, magnetic susceptibility measurements and spectroscopic techniques like MS, IR, UV and NMR. The high molar conductivity values of the complexes confirmed the presence of counter ions in the lattice of the cationic complexes. The molecular structure of the aroylhydrazone and its complexes have been resolved using single crystal XRD studies. In the solid state, the aroylhydrazone exists in the amido form as evident from the IR and XRD studies. The tridentate nature of the NNO donor aroylhydrazone was also confirmed from the IR spectral studies. XRD studies reveal that in all complexes, the tridentate aroylhydrazone coordinates to the Co(III) center via pyridine nitrogen, azomethine nitrogen and iminolate oxygen and found to possess distorted octahedral geometry. The complexes are bis-ligated cationic complexes in which chloride and nitrate ions act as counter ions. The antibacterial and antifungal activities of the aroylhydrazone and its Co(III) complexes have been screened against bacterial species Staphylococcus aureus, Enterobacter aerogenes, Bacillus subtilis, Streptococcus pyogenes, Klebsiella pneumonia, Salmonella typhi and Escherichia coli. The antifungal activity was also checked using fungi Aspergillus niger, Penicillium chrysogenum and Rhizopus oryzae. From the activity data we can infer that the metal complexes have better biological activity than the metal free ligand against the bacterial and fungal species which were tested.\n
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\n\n \n \n \n \n \n \n Solvent Effects: A Signature of J- and H-Aggregate of Carbon Nanodots in Polar Solvents.\n \n \n \n \n\n\n \n Devi, J. S. A.; Aparna, R. S.; Anjana, R. R.; Nebu, J.; Anju, S. M.; and George, S.\n\n\n \n\n\n\n
The Journal of Physical Chemistry A, 123(34): 7335–7542. August 2019.\n
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@article{devi_solvent_2019,\n\ttitle = {Solvent {Effects}: {A} {Signature} of {J}- and {H}-{Aggregate} of {Carbon} {Nanodots} in {Polar} {Solvents}},\n\tvolume = {123},\n\tcopyright = {Copyright © 2019 American Chemical Society},\n\tissn = {1089-5639},\n\tshorttitle = {Solvent {Effects}},\n\turl = {https://pubs.acs.org/doi/abs/10.1021/acs.jpca.9b04568},\n\tdoi = {10.1021/acs.jpca.9b04568},\n\tabstract = {The secret behind excitation-dependent/-independent photoluminescence of carbon nanodots (CDs) is not yet revealed completely. To address this issue, a detailed investigation on solvent polarity-dependent optical properties of citric acid–urea co-derived nitrogen-doped carbon nanodots (NCDs) was carried out. The interpretation on UV–visible spectral data reveals the presence of H-aggregates formed through hydrogen bonding. In addition, dipole–dipole interaction-mediated J-aggregates are clearly evident. The broad and intense excitation band of NCDs is mostly contributed by highly emissive J-like self-assembly of H-aggregates in polar solvents. Time-resolved fluorescence spectra of NCDs show triexponential decay kinetics. The three lifetime components correspond to long-lived H-aggregates, short-lived J-aggregates, and JH-aggregates of intermediate lifetime. Moreover, fluorescence of NCD is influenced by concentration and storage time. Accordingly, mismatch in spectral shapes of excitation and absorption spectra of NCD can be successfully correlated to aggregate species of NCDs that exist even in very dilute solutions.},\n\tlanguage = {en},\n\tnumber = {34},\n\turldate = {2024-10-15},\n\tjournal = {The Journal of Physical Chemistry A},\n\tauthor = {Devi, J. S. Anjali and Aparna, R. S. and Anjana, R. R. and Nebu, John and Anju, S. Madanan and George, Sony},\n\tmonth = aug,\n\tyear = {2019},\n\tpages = {7335--7542},\n}\n\n\n\n
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\n The secret behind excitation-dependent/-independent photoluminescence of carbon nanodots (CDs) is not yet revealed completely. To address this issue, a detailed investigation on solvent polarity-dependent optical properties of citric acid–urea co-derived nitrogen-doped carbon nanodots (NCDs) was carried out. The interpretation on UV–visible spectral data reveals the presence of H-aggregates formed through hydrogen bonding. In addition, dipole–dipole interaction-mediated J-aggregates are clearly evident. The broad and intense excitation band of NCDs is mostly contributed by highly emissive J-like self-assembly of H-aggregates in polar solvents. Time-resolved fluorescence spectra of NCDs show triexponential decay kinetics. The three lifetime components correspond to long-lived H-aggregates, short-lived J-aggregates, and JH-aggregates of intermediate lifetime. Moreover, fluorescence of NCD is influenced by concentration and storage time. Accordingly, mismatch in spectral shapes of excitation and absorption spectra of NCD can be successfully correlated to aggregate species of NCDs that exist even in very dilute solutions.\n
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\n\n \n \n \n \n \n \n Reversible fluorescence modulation of BSA stabilised copper nanoclusters for the selective detection of protamine and heparin.\n \n \n \n \n\n\n \n Aparna, R. S.; Devi, J. S. A.; Anjana, R. R.; Nebu, J.; and George, S.\n\n\n \n\n\n\n
Analyst, 144(5): 1799–1808. February 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
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@article{aparna_reversible_2019,\n\ttitle = {Reversible fluorescence modulation of {BSA} stabilised copper nanoclusters for the selective detection of protamine and heparin},\n\tvolume = {144},\n\tissn = {1364-5528},\n\turl = {https://pubs.rsc.org/en/content/articlelanding/2019/an/c8an01703d},\n\tdoi = {10.1039/C8AN01703D},\n\tabstract = {Protamine and heparin are the most important polyionic drugs used during surgeries and extracorporeal therapies. In this article, a selective and sensitive fluorescence method for the detection of both protamine and heparin was developed by using bovine serum albumin stabilised copper nanoclusters. Blue emitting fluorescent copper nanoclusters were synthesized in aqueous solution using bovine serum albumin as a capping agent and a reducing agent. A one pot microwave assisted method was adopted to synthesize fluorescent copper nanoclusters showing emission at 410 nm upon excitation at 330 nm. The fluorescence of copper nanoclusters was found to be enhanced after the addition of protamine and the limit of detection obtained is 0.12 ng mL−1. The significant enhancement in fluorescence can be attributed to the electrostatic interactions between the copper nanocluster and protamine. In contrast, the enhanced fluorescence intensity of the copper nanocluster with protamine added was decreased after the addition of heparin, and the copper nanocluster regained its original fluorescence intensity. This can be attributed to the strong interaction of protamine with heparin and the limit of detection was calculated as 0.0406 ng mL−1. The selectivity and sensitivity of the sensor for both protamine and heparin were also determined in the presence of potentially co-existing biomolecules, cations, and anions and satisfactory results were obtained. Additionally the validity of the proposed protamine and heparin sensor was attested in real sample matrices such as human urine samples and human blood serum samples. The results exhibited that the recovery percentage of protamine and heparin reached 98–99\\% and 92–99\\% in urine samples and 97–99\\% in serum samples.},\n\tlanguage = {en},\n\tnumber = {5},\n\turldate = {2024-10-16},\n\tjournal = {Analyst},\n\tauthor = {Aparna, R. S. and Devi, J. S. Anjali and Anjana, R. R. and Nebu, John and George, Sony},\n\tmonth = feb,\n\tyear = {2019},\n\tpages = {1799--1808},\n}\n\n\n\n\n\n\n\n
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\n Protamine and heparin are the most important polyionic drugs used during surgeries and extracorporeal therapies. In this article, a selective and sensitive fluorescence method for the detection of both protamine and heparin was developed by using bovine serum albumin stabilised copper nanoclusters. Blue emitting fluorescent copper nanoclusters were synthesized in aqueous solution using bovine serum albumin as a capping agent and a reducing agent. A one pot microwave assisted method was adopted to synthesize fluorescent copper nanoclusters showing emission at 410 nm upon excitation at 330 nm. The fluorescence of copper nanoclusters was found to be enhanced after the addition of protamine and the limit of detection obtained is 0.12 ng mL−1. The significant enhancement in fluorescence can be attributed to the electrostatic interactions between the copper nanocluster and protamine. In contrast, the enhanced fluorescence intensity of the copper nanocluster with protamine added was decreased after the addition of heparin, and the copper nanocluster regained its original fluorescence intensity. This can be attributed to the strong interaction of protamine with heparin and the limit of detection was calculated as 0.0406 ng mL−1. The selectivity and sensitivity of the sensor for both protamine and heparin were also determined in the presence of potentially co-existing biomolecules, cations, and anions and satisfactory results were obtained. Additionally the validity of the proposed protamine and heparin sensor was attested in real sample matrices such as human urine samples and human blood serum samples. The results exhibited that the recovery percentage of protamine and heparin reached 98–99% and 92–99% in urine samples and 97–99% in serum samples.\n
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\n\n \n \n \n \n \n \n Recent Advances in Cross-linked Polyethylene Based Nanocomposites for High Voltage Engineering Applications: A Critical Review.\n \n \n \n \n\n\n \n Thomas, J.; Joseph, B.; Jose, J. P; Maria, H. J; Main, P.; Rahman, A. A.; Francis, B.; Ahmad, Z.; and Thomas, S.\n\n\n \n\n\n\n
Industrial & Engineering Chemistry Research, 58(46): 20863–20879. November 2019.\n
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@article{thomas_recent_2019,\n\ttitle = {Recent {Advances} in {Cross}-linked {Polyethylene} {Based} {Nanocomposites} for {High} {Voltage} {Engineering} {Applications}: {A} {Critical} {Review}},\n\tvolume = {58},\n\turl = {https://www.academia.edu/download/72184565/acs.iecr.9b02172.pdf},\n\tlanguage = {en},\n\tnumber = {46},\n\tjournal = {Industrial \\& Engineering Chemistry Research},\n\tauthor = {Thomas, Jince and Joseph, Blessy and Jose, Josmin P and Maria, Hanna J and Main, Priyanka and Rahman, Azerai Ali and Francis, Bejoy and Ahmad, Zakiah and Thomas, Sabu},\n\tmonth = nov,\n\tyear = {2019},\n\tpages = {20863--20879},\n}\n\n\n\n
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\n\n \n \n \n \n \n \n Rapid response of dopamine towards insitu synthesised copper nanocluster in presence of H2O2.\n \n \n \n \n\n\n \n Aparna, R. S.; Devi, J. S. A.; Nebu, J.; Syamchand, S. S; and George, S.\n\n\n \n\n\n\n
Journal of Photochemistry and Photobiology A: Chemistry, 379: 63–71. June 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
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@article{aparna_rapid_2019,\n\ttitle = {Rapid response of dopamine towards \\textit{insitu} synthesised copper nanocluster in presence of {H2O2}},\n\tvolume = {379},\n\tissn = {1010-6030},\n\turl = {https://www.sciencedirect.com/science/article/pii/S1010603018317945},\n\tdoi = {10.1016/j.jphotochem.2019.04.043},\n\tabstract = {Rapid and real-time monitoring of catecholamine neurotransmitter dopamine receives immense importance since it plays a crucial role as a local chemical messenger for interneuronal communications in mammalian central and peripheral nervous systems. In the present study, blue emitting copper nanocluster was synthesized in presence (BSA CuNC1) and absence (BSA CuNC2) of hydrogen peroxide and fluorescence response of the two systems towards dopamine was analysed. At an excitation of 355 nm, fast response towards dopamine detection was obtained for BSA CuNC1 system having limit of detection 0.1637 pM. The fast interaction of dopamine with BSA CuNC1 can be attributed to the intrinsic peroxidase like activity of CuNC in presence of H2O2. On the other hand, the response of dopamine towards BSA CuNC2 was very slow with a limit of detection 0.024 nM. Encouraged by the fast response and low limit of detection, the BSA CuNC1 system was effectively applied for dopamine detection in real sample matrices. The recovery percentage for serum sample obtained was in the range 90–98.33\\% and for urine sample was in the range 89–96.66\\%. In addition to that, a paper test strips using BSA CuNC1 was developed which exhibited colour change as well as fluorescence quenching, creates a low cost approach for the fast monitoring of dopamine.},\n\turldate = {2024-10-15},\n\tjournal = {Journal of Photochemistry and Photobiology A: Chemistry},\n\tauthor = {Aparna, R. S. and Devi, J. S. Anjali and Nebu, John and Syamchand, S. S and George, Sony},\n\tmonth = jun,\n\tyear = {2019},\n\tkeywords = {Copper nanoclusters, Dopamine, Fluorescence, HO, Paper-strip detection, Real sample analysis},\n\tpages = {63--71},\n}\n\n\n\n
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\n Rapid and real-time monitoring of catecholamine neurotransmitter dopamine receives immense importance since it plays a crucial role as a local chemical messenger for interneuronal communications in mammalian central and peripheral nervous systems. In the present study, blue emitting copper nanocluster was synthesized in presence (BSA CuNC1) and absence (BSA CuNC2) of hydrogen peroxide and fluorescence response of the two systems towards dopamine was analysed. At an excitation of 355 nm, fast response towards dopamine detection was obtained for BSA CuNC1 system having limit of detection 0.1637 pM. The fast interaction of dopamine with BSA CuNC1 can be attributed to the intrinsic peroxidase like activity of CuNC in presence of H2O2. On the other hand, the response of dopamine towards BSA CuNC2 was very slow with a limit of detection 0.024 nM. Encouraged by the fast response and low limit of detection, the BSA CuNC1 system was effectively applied for dopamine detection in real sample matrices. The recovery percentage for serum sample obtained was in the range 90–98.33% and for urine sample was in the range 89–96.66%. In addition to that, a paper test strips using BSA CuNC1 was developed which exhibited colour change as well as fluorescence quenching, creates a low cost approach for the fast monitoring of dopamine.\n
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\n\n \n \n \n \n \n \n Potential Hosts of Sri Lankan Cassava Mosaic Virus Evaluated Through Whitefly Inoculation.\n \n \n \n \n\n\n \n Anitha, J.; T, M.; and S, E.\n\n\n \n\n\n\n
JOURNAL OF ROOT CROPS, 45(2): 55–61. 2019.\n
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Paper\n \n \n\n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
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@article{anitha_potential_2019,\n\ttitle = {Potential {Hosts} of {Sri} {Lankan} {Cassava} {Mosaic} {Virus} {Evaluated} {Through} {Whitefly} {Inoculation}},\n\tvolume = {45},\n\tcopyright = {Copyright (c)},\n\tissn = {2454-9053},\n\turl = {https://journal.isrc.in/index.php/jrc/article/view/564},\n\tabstract = {Sri Lankan Cassava Mosaic Virus (SLCMV) causes mosaic disease in cassava in India, Sri Lanka and south east Asian countries. Among the 98 plants species/ cultivars belonging to seven families screened/ tested against the virus, SLCMV was transmitted to 42 species of plants belonging to Solanaceae and 4 species of plants belonging to Euphorbiaceae through whitefly inoculation. The incubation period for symptom appearance varied from 6-49 days depending on the species. Presence or absence of SLCMV in the host was confirmed through PCR.},\n\tlanguage = {en},\n\tnumber = {2},\n\turldate = {2024-10-15},\n\tjournal = {JOURNAL OF ROOT CROPS},\n\tauthor = {Anitha, Jose and T, Makeshkumar and S, Edison},\n\tyear = {2019},\n\tpages = {55--61},\n}\n\n\n\n
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\n Sri Lankan Cassava Mosaic Virus (SLCMV) causes mosaic disease in cassava in India, Sri Lanka and south east Asian countries. Among the 98 plants species/ cultivars belonging to seven families screened/ tested against the virus, SLCMV was transmitted to 42 species of plants belonging to Solanaceae and 4 species of plants belonging to Euphorbiaceae through whitefly inoculation. The incubation period for symptom appearance varied from 6-49 days depending on the species. Presence or absence of SLCMV in the host was confirmed through PCR.\n
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\n\n \n \n \n \n \n \n Potassium triiodide-quenched gold nanocluster as a fluorescent turn-on probe for sensing cysteine/homocysteine in human serum.\n \n \n \n \n\n\n \n J, N.; Js, A. D.; Rs, A.; B, A.; Gm, L.; and G, S.\n\n\n \n\n\n\n
Analytical and bioanalytical chemistry, 411(5). February 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
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@article{j_potassium_2019,\n\ttitle = {Potassium triiodide-quenched gold nanocluster as a fluorescent turn-on probe for sensing cysteine/homocysteine in human serum},\n\tvolume = {411},\n\tissn = {1618-2650},\n\turl = {https://pubmed.ncbi.nlm.nih.gov/30637437/},\n\tdoi = {10.1007/s00216-018-1511-y},\n\tabstract = {A fluorescent sensing platform using KI₃-quenched bovine serum albumin stabilized gold nanoclusters has been designed and used as a fluorescent probe for the turn-on detection of homocysteine/cysteine (Cys/Hcy). The fluorescence of gold nanoclusters was quenched by iodine. The fluorescenc …},\n\tlanguage = {en},\n\tnumber = {5},\n\turldate = {2024-10-16},\n\tjournal = {Analytical and bioanalytical chemistry},\n\tauthor = {J, Nebu and Js, Anjali Devi and Rs, Aparna and B, Aswathy and Gm, Lekha and G, Sony},\n\tmonth = feb,\n\tyear = {2019},\n\tpmid = {30637437},\n}\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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\n A fluorescent sensing platform using KI₃-quenched bovine serum albumin stabilized gold nanoclusters has been designed and used as a fluorescent probe for the turn-on detection of homocysteine/cysteine (Cys/Hcy). The fluorescence of gold nanoclusters was quenched by iodine. The fluorescenc …\n
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\n\n \n \n \n \n \n \n Photoluminescence sensing of bilirubin in human serum using l-cysteine tailored manganese doped zinc sulphide quantum dots.\n \n \n \n \n\n\n \n Abha, K.; Nebu, J.; Anjali Devi, J. S.; Aparna, R. S.; Anjana, R. R.; Aswathy, A. O.; and George, S.\n\n\n \n\n\n\n
Sensors and Actuators B: Chemical, 282: 300–308. March 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
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@article{abha_photoluminescence_2019,\n\ttitle = {Photoluminescence sensing of bilirubin in human serum using l-cysteine tailored manganese doped zinc sulphide quantum dots},\n\tvolume = {282},\n\tissn = {0925-4005},\n\turl = {https://www.sciencedirect.com/science/article/pii/S0925400518320185},\n\tdoi = {10.1016/j.snb.2018.11.063},\n\tabstract = {Bilirubin (BR) is a protective antioxidant generated as end-product of heme catabolism in human. However, BR accumulation in biological tissues in connection with neonatal and hereditary jaundice causes severe hyperbilirubinemia and neurotoxicity. Herein, a fluorescence turn-off sensor for the detection of BR, a major biomarker for jaundice, is designed based on l-cysteine capped manganese doped zinc sulphide quantum dots (Mn:ZnS QDs). The QDs were synthesized by a microwave assisted chemical co-precipitation method. Under optimum conditions, the luminescence quenching response of Mn:ZnS QDs can be effectively used for detection of BR in the linear range of 10.99 μM - 63.84 μM BR. The limit of detection (LOD) is as low as 1.8 μM and limit of quantification (LOQ) is 6 μM. The plausible mechanism behind BR induced luminescence quenching is reductive photo-induced electron transfer (PET) in which Mn:ZnS QDs act as electron acceptor and BR act as electron donor. The developed sensor show good selectivity for BR over other co-existing biomolecules such as creatine, cholesterol, bisphenol, glutathione, uric acid, urea, hemoglobin, fructose, galactose and glucose. The developed sensor was validated by the detection of BR in spiked human serum and urine samples. For practical applications, a paper strip based sensor was also developed.},\n\turldate = {2024-10-16},\n\tjournal = {Sensors and Actuators B: Chemical},\n\tauthor = {Abha, K. and Nebu, John and Anjali Devi, J. S. and Aparna, R. S. and Anjana, R. R. and Aswathy, A. O. and George, Sony},\n\tmonth = mar,\n\tyear = {2019},\n\tkeywords = {Antioxidant, Biosensor, Doped quantum dots, Hyperbilirubinemia, Jaundice, Luminescence},\n\tpages = {300--308},\n}\n\n\n\n\n\n\n\n\n\n\n\n
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\n Bilirubin (BR) is a protective antioxidant generated as end-product of heme catabolism in human. However, BR accumulation in biological tissues in connection with neonatal and hereditary jaundice causes severe hyperbilirubinemia and neurotoxicity. Herein, a fluorescence turn-off sensor for the detection of BR, a major biomarker for jaundice, is designed based on l-cysteine capped manganese doped zinc sulphide quantum dots (Mn:ZnS QDs). The QDs were synthesized by a microwave assisted chemical co-precipitation method. Under optimum conditions, the luminescence quenching response of Mn:ZnS QDs can be effectively used for detection of BR in the linear range of 10.99 μM - 63.84 μM BR. The limit of detection (LOD) is as low as 1.8 μM and limit of quantification (LOQ) is 6 μM. The plausible mechanism behind BR induced luminescence quenching is reductive photo-induced electron transfer (PET) in which Mn:ZnS QDs act as electron acceptor and BR act as electron donor. The developed sensor show good selectivity for BR over other co-existing biomolecules such as creatine, cholesterol, bisphenol, glutathione, uric acid, urea, hemoglobin, fructose, galactose and glucose. The developed sensor was validated by the detection of BR in spiked human serum and urine samples. For practical applications, a paper strip based sensor was also developed.\n
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\n\n \n \n \n \n \n \n Phenolics, tannins, flavonoids and anthocyanins contents influenced antioxidant and anticancer activities of Rubus fruits from Western Ghats, India.\n \n \n \n \n\n\n \n Muniyandi, K.; George, E.; Sathyanarayanan, S.; George, B. P.; Abrahamse, H.; Thamburaj, S.; and Thangaraj, P.\n\n\n \n\n\n\n
Food Science and Human Wellness, 8(1): 73–81. March 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
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@article{muniyandi_phenolics_2019,\n\ttitle = {Phenolics, tannins, flavonoids and anthocyanins contents influenced antioxidant and anticancer activities of {Rubus} fruits from {Western} {Ghats}, {India}},\n\tvolume = {8},\n\tissn = {2213-4530},\n\turl = {https://www.sciencedirect.com/science/article/pii/S2213453018301010},\n\tdoi = {10.1016/j.fshw.2019.03.005},\n\tabstract = {Rubus fruits are rich in nutrition with a wide range of phytochemical and consumed by humans, but many of its wild varieties are not commercially useful. Phytochemical exploration of these wild fruits could improve the commercial usage of these Rubus species. This study focuses to analyze the phytochemical, antioxidant and cytotoxicity of three wild Rubus ellipticus, R. niveus and R. fairholmianus fruits comparatively, which has not revealed. The in vitro antioxidant studies indicated the ethyl acetate and methanol extracts of studied Rubus species competent in scavenging different stable and generated radical. The correlation and regression analysis also statistically supported the contents in the extracts could act against various radicals. Correlation between phytochemical constituent and radical scavenging activity found to be highly positive. The results acquired from this investigation revealed that they are equally competent and could be recommended as dietary supplements or as nutraceuticals.},\n\tnumber = {1},\n\turldate = {2024-10-10},\n\tjournal = {Food Science and Human Wellness},\n\tauthor = {Muniyandi, Kasipandi and George, Elizabeth and Sathyanarayanan, Saikumar and George, Blassan P. and Abrahamse, Heidi and Thamburaj, Suman and Thangaraj, Parimelazhagan},\n\tmonth = mar,\n\tyear = {2019},\n\tkeywords = {Anticancer, Antioxidant, Flavonoids, Nutraceuticals, Phenolics},\n\tpages = {73--81},\n}\n\n\n\n
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\n Rubus fruits are rich in nutrition with a wide range of phytochemical and consumed by humans, but many of its wild varieties are not commercially useful. Phytochemical exploration of these wild fruits could improve the commercial usage of these Rubus species. This study focuses to analyze the phytochemical, antioxidant and cytotoxicity of three wild Rubus ellipticus, R. niveus and R. fairholmianus fruits comparatively, which has not revealed. The in vitro antioxidant studies indicated the ethyl acetate and methanol extracts of studied Rubus species competent in scavenging different stable and generated radical. The correlation and regression analysis also statistically supported the contents in the extracts could act against various radicals. Correlation between phytochemical constituent and radical scavenging activity found to be highly positive. The results acquired from this investigation revealed that they are equally competent and could be recommended as dietary supplements or as nutraceuticals.\n
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\n\n \n \n \n \n \n \n Occurrence and Distribution of Sri Lankan Cassava Mosaic Virus in the Stems of Cassava.\n \n \n \n \n\n\n \n Anitha, J.; S, E.; and T, M.\n\n\n \n\n\n\n
JOURNAL OF ROOT CROPS, 45(1): 32–40. December 2019.\n
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Paper\n \n \n\n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
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@article{anitha_occurrence_2019,\n\ttitle = {Occurrence and {Distribution} of {Sri} {Lankan} {Cassava} {Mosaic} {Virus} in the {Stems} of {Cassava}},\n\tvolume = {45},\n\tcopyright = {Copyright (c)},\n\tissn = {2454-9053},\n\turl = {https://journal.isrc.in/index.php/jrc/article/view/552},\n\tabstract = {The distribution of Sri Lankan cassava mosaic virus (SLCMV) in the buds regenerated from the nodes of stem cuttings varied with different varieties. Using different diagnostic techniques (ELISA, PCR and NASH), the SLCMV distribution in 8 varieties of cassava viz., Sree Sahya, Sree Prakash, Sree Visakham, Sree Padmanabha, Sree Vijaya, M-4, H-165 and H-226 were diagnosed. Top portions (one third of total stem used for planting) of the stems in all the varieties tested had maximum virus accumulation except Sree Padmanabha, which showed high virus accumulation in bottom portion. Similar results were obtained from the diagnosis of bark samples of all the varieties with variation in the virus accumulation level.},\n\tlanguage = {en},\n\tnumber = {1},\n\turldate = {2024-10-15},\n\tjournal = {JOURNAL OF ROOT CROPS},\n\tauthor = {Anitha, Jose and S, Edison and T, Makeshkumar},\n\tmonth = dec,\n\tyear = {2019},\n\tpages = {32--40},\n}\n\n\n\n\n\n\n\n
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\n The distribution of Sri Lankan cassava mosaic virus (SLCMV) in the buds regenerated from the nodes of stem cuttings varied with different varieties. Using different diagnostic techniques (ELISA, PCR and NASH), the SLCMV distribution in 8 varieties of cassava viz., Sree Sahya, Sree Prakash, Sree Visakham, Sree Padmanabha, Sree Vijaya, M-4, H-165 and H-226 were diagnosed. Top portions (one third of total stem used for planting) of the stems in all the varieties tested had maximum virus accumulation except Sree Padmanabha, which showed high virus accumulation in bottom portion. Similar results were obtained from the diagnosis of bark samples of all the varieties with variation in the virus accumulation level.\n
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\n\n \n \n \n \n \n \n Novel bio compactable silver nanowires and nanocubes: An effective treatment against carbapenem and vancomycin resistant strains isolated from cancer patients.\n \n \n \n \n\n\n \n Jose, J.; Nair, A. K.; Kalarikkal, N.; Oluwafemi, O.; and Thomas, S.\n\n\n \n\n\n\n
Journal of Saudi Chemical Society, 23(8): 1090–1101. December 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
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@article{jose_novel_2019,\n\ttitle = {Novel bio compactable silver nanowires and nanocubes: {An} effective treatment against carbapenem and vancomycin resistant strains isolated from cancer patients},\n\tvolume = {23},\n\tissn = {1319-6103},\n\tshorttitle = {Novel bio compactable silver nanowires and nanocubes},\n\turl = {https://www.sciencedirect.com/science/article/pii/S1319610319300717},\n\tdoi = {10.1016/j.jscs.2019.06.004},\n\tabstract = {Blood stream infections in the cancer patients are a critical problem which leads to considerable rate of mortality and morbidity. In view of this herein, we account the response of Poly Vinyl Pyrrolidone (PVP) coated silver nanowires (Ag-NWs) and silver nano cubes (Ag-NCs) towards carbapenem (Escherichia coli) and vancomycin (Staphylococcus aureus) resistant strains as well as to human epithelial cells. The prepared PVP capped silver nanomaterials were in the range of 80 nm (Ag-NC) and 25 nm (Ag-NW) as observed from Transmission Electron Microscopy (TEM). Though the selected strains were resistant to carbapenem and vancomycin, PVP capped Ag-NWs and Ag-NCs could inhibit the growth of these strains. These nanomaterials could break the cell wall and damage the genetic material of these strains as observed by death rate assay and alkaline comet assay. Furthermore, we have shown that toxicity of Ag-NWs and Ag-NCs precisely follows the dose retort pattern. Even though the resistant strains were susceptible to a concentration of 10 µg ml−1 of silver nanomaterials the epithelial cells were not affected by the same concentration. It is also confirmed with live dead staining assay and observed that metabolic activities of epithelial cells were not affected by a concentration of 10 µg ml−1. Overall, this work suggests that these nanomaterials can be utilized to treat the multiple drug resistant strains from cancer patients.},\n\tnumber = {8},\n\turldate = {2024-10-16},\n\tjournal = {Journal of Saudi Chemical Society},\n\tauthor = {Jose, Jiya and Nair, Anju K. and Kalarikkal, Nandakumar and Oluwafemi, Oluwatobi and Thomas, Sabu},\n\tmonth = dec,\n\tyear = {2019},\n\tkeywords = {Biocompatibility, Cancer, Genotoxicity, Multiple drug resistance, Septicaemia, Silver nanomaterials},\n\tpages = {1090--1101},\n}\n\n\n\n\n\n\n\n\n\n\n\n
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\n Blood stream infections in the cancer patients are a critical problem which leads to considerable rate of mortality and morbidity. In view of this herein, we account the response of Poly Vinyl Pyrrolidone (PVP) coated silver nanowires (Ag-NWs) and silver nano cubes (Ag-NCs) towards carbapenem (Escherichia coli) and vancomycin (Staphylococcus aureus) resistant strains as well as to human epithelial cells. The prepared PVP capped silver nanomaterials were in the range of 80 nm (Ag-NC) and 25 nm (Ag-NW) as observed from Transmission Electron Microscopy (TEM). Though the selected strains were resistant to carbapenem and vancomycin, PVP capped Ag-NWs and Ag-NCs could inhibit the growth of these strains. These nanomaterials could break the cell wall and damage the genetic material of these strains as observed by death rate assay and alkaline comet assay. Furthermore, we have shown that toxicity of Ag-NWs and Ag-NCs precisely follows the dose retort pattern. Even though the resistant strains were susceptible to a concentration of 10 µg ml−1 of silver nanomaterials the epithelial cells were not affected by the same concentration. It is also confirmed with live dead staining assay and observed that metabolic activities of epithelial cells were not affected by a concentration of 10 µg ml−1. Overall, this work suggests that these nanomaterials can be utilized to treat the multiple drug resistant strains from cancer patients.\n
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\n\n \n \n \n \n \n \n In Situ Decoration of Gold Nanoparticles on Graphene Oxide via Nanosecond Laser Ablation for Remarkable Chemical Sensing and Catalysis.\n \n \n \n \n\n\n \n Nancy, P.; Nair, A. K.; Antoine, R.; Thomas, S.; and Kalarikkal, N.\n\n\n \n\n\n\n
Nanomaterials, 9(9): 1201. September 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n \n \n \n \n \n \n \n \n\n\n\n
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@article{nancy_situ_2019,\n\ttitle = {In {Situ} {Decoration} of {Gold} {Nanoparticles} on {Graphene} {Oxide} via {Nanosecond} {Laser} {Ablation} for {Remarkable} {Chemical} {Sensing} and {Catalysis}},\n\tvolume = {9},\n\tcopyright = {http://creativecommons.org/licenses/by/3.0/},\n\tissn = {2079-4991},\n\turl = {https://www.mdpi.com/2079-4991/9/9/1201},\n\tdoi = {10.3390/nano9091201},\n\tabstract = {Gold decorated graphene-based nano-hybrids find extensive research interest due to their enhanced chemical catalytic performance and biochemical sensing. The unique physicochemical properties and the very large surface area makes them propitious platform for the rapid buildouts of science and technology. Graphene serves as an outstanding matrix for anchoring numerous nanomaterials because of its atomically thin 2D morphological features. Herein, we have designed a metal-graphene nano-hybrid through pulsed laser ablation. Commercially available graphite powder was employed for the preparation of graphene oxide (GO) using modified Hummers’ method. A solid, thin gold (Au) foil was ablated in an aqueous suspension of GO using second harmonic wavelength (532 nm) of the Nd:YAG laser for immediate generation of the Au-GO nano-hybrid. The synthesis strategy employed here does not entail any detrimental chemical reagents and hence avoids the inclusion of reagent byproducts to the reaction mixture, toxicity, and environmental or chemical contamination. Optical and morphological characterizations were performed to substantiate the successful anchoring of Au nanoparticles (Au NPs) on the GO sheets. Remarkably, these photon-generated nano-hybrids can act as an excellent surface enhanced Raman spectroscopy (SERS) platform for the sensing/detection of the 4-mercaptobenzoic acid (4-MBA) with a very low detection limit of 1 × 10−12 M and preserves better reproducibility also. In addition, these hybrid materials were found to act as an effective catalyst for the reduction of 4-nitrophenol (4-NP). Thus, this is a rapid, mild, efficient and green synthesis approach for the fabrication of active organometallic sensors and catalysts.},\n\tlanguage = {en},\n\tnumber = {9},\n\turldate = {2024-10-16},\n\tjournal = {Nanomaterials},\n\tauthor = {Nancy, Parvathy and Nair, Anju K. and Antoine, Rodolphe and Thomas, Sabu and Kalarikkal, Nandakumar},\n\tmonth = sep,\n\tyear = {2019},\n\tkeywords = {Au-GO nano-hybrid, gold nanoparticles, graphene oxide, laser ablation},\n\tpages = {1201},\n}\n\n\n\n
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\n Gold decorated graphene-based nano-hybrids find extensive research interest due to their enhanced chemical catalytic performance and biochemical sensing. The unique physicochemical properties and the very large surface area makes them propitious platform for the rapid buildouts of science and technology. Graphene serves as an outstanding matrix for anchoring numerous nanomaterials because of its atomically thin 2D morphological features. Herein, we have designed a metal-graphene nano-hybrid through pulsed laser ablation. Commercially available graphite powder was employed for the preparation of graphene oxide (GO) using modified Hummers’ method. A solid, thin gold (Au) foil was ablated in an aqueous suspension of GO using second harmonic wavelength (532 nm) of the Nd:YAG laser for immediate generation of the Au-GO nano-hybrid. The synthesis strategy employed here does not entail any detrimental chemical reagents and hence avoids the inclusion of reagent byproducts to the reaction mixture, toxicity, and environmental or chemical contamination. Optical and morphological characterizations were performed to substantiate the successful anchoring of Au nanoparticles (Au NPs) on the GO sheets. Remarkably, these photon-generated nano-hybrids can act as an excellent surface enhanced Raman spectroscopy (SERS) platform for the sensing/detection of the 4-mercaptobenzoic acid (4-MBA) with a very low detection limit of 1 × 10−12 M and preserves better reproducibility also. In addition, these hybrid materials were found to act as an effective catalyst for the reduction of 4-nitrophenol (4-NP). Thus, this is a rapid, mild, efficient and green synthesis approach for the fabrication of active organometallic sensors and catalysts.\n
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\n\n \n \n \n \n \n \n Human Rights Debating Approaches and Concepts.\n \n \n \n \n\n\n \n Thomas, S. A.\n\n\n \n\n\n\n
JOURNAL OF POLITY AND SOCIETY, 11(1&2): 99–110. December 2019.\n
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@article{thomas_human_2019,\n\ttitle = {Human {Rights} {Debating} {Approaches} and {Concepts}},\n\tvolume = {11},\n\tissn = {0976-0210},\n\turl = {https://journalspoliticalscience.com/},\n\tlanguage = {English},\n\tnumber = {1\\&2},\n\tjournal = {JOURNAL OF POLITY AND SOCIETY},\n\tauthor = {Thomas, Sony Achamma},\n\tmonth = dec,\n\tyear = {2019},\n\tpages = {99--110},\n}\n\n\n\n
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\n\n \n \n \n \n \n \n EFFECT OF IONIC LIQUID MODIFIED MWCNT ON THE RHEOLOGICAL AND MICROSTRUCTURAL DEVELOPMENTS IN STYRENE BUTADIENE RUBBER NANOCOMPOSITES.\n \n \n \n \n\n\n \n Abraham, J.; Zachariah, A. K.; Wilson, R.; Ibarra-Gómez, R.; Muller, R.; George, S. C.; Kalarikkal, N.; and Thomas, S.\n\n\n \n\n\n\n
Rubber Chemistry and Technology, 92(3): 531–545. July 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
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@article{abraham_effect_2019,\n\ttitle = {{EFFECT} {OF} {IONIC} {LIQUID} {MODIFIED} {MWCNT} {ON} {THE} {RHEOLOGICAL} {AND} {MICROSTRUCTURAL} {DEVELOPMENTS} {IN} {STYRENE} {BUTADIENE} {RUBBER} {NANOCOMPOSITES}},\n\tvolume = {92},\n\tissn = {0035-9475},\n\turl = {https://doi.org/10.5254/rct.19.81494},\n\tdoi = {10.5254/rct.19.81494},\n\tabstract = {Ionic liquid modified multiwalled carbon nanotube (MWCNT) based styrene–butadiene rubber (SBR) nanocomposites were prepared with the two-roll mill mixing method, and the rheological measurements were used to study the dispersion of MWCNTs on a microscopic scale and its compatibility with the SBR matrix. Viscous liquid-like rheological behavior at low MWCNT loadings and pseudo-solid-like rheological response at high MWCNT loadings were observed, showing the gradual transformation from individual structures of MWCNTs to polymer bridged MWCNT networks. A decrease in the mobility of SBR macromolecular chains by the geometric confinement of three-dimensional networks of MWCNTs further confirms the interdeveloped pseudo-solid behavior of filled composites. Dynamic viscoelasticity data have been compared with the theoretical Carreau–Yasuda equation. Transmission electron microscopy of the samples reveals that MWCNTs are randomly dispersed in the rubber matrix. Finally the nature of the filler association and its role in the nonlinear viscoelastic properties at large strain amplitudes were investigated.},\n\tnumber = {3},\n\turldate = {2024-10-16},\n\tjournal = {Rubber Chemistry and Technology},\n\tauthor = {Abraham, Jiji and Zachariah, Ajesh K. and Wilson, Runcy and Ibarra-Gómez, Rigoberto and Muller, Rene and George, Soney C. and Kalarikkal, Nandakumar and Thomas, Sabu},\n\tmonth = jul,\n\tyear = {2019},\n\tpages = {531--545},\n}\n\n\n\n
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\n Ionic liquid modified multiwalled carbon nanotube (MWCNT) based styrene–butadiene rubber (SBR) nanocomposites were prepared with the two-roll mill mixing method, and the rheological measurements were used to study the dispersion of MWCNTs on a microscopic scale and its compatibility with the SBR matrix. Viscous liquid-like rheological behavior at low MWCNT loadings and pseudo-solid-like rheological response at high MWCNT loadings were observed, showing the gradual transformation from individual structures of MWCNTs to polymer bridged MWCNT networks. A decrease in the mobility of SBR macromolecular chains by the geometric confinement of three-dimensional networks of MWCNTs further confirms the interdeveloped pseudo-solid behavior of filled composites. Dynamic viscoelasticity data have been compared with the theoretical Carreau–Yasuda equation. Transmission electron microscopy of the samples reveals that MWCNTs are randomly dispersed in the rubber matrix. Finally the nature of the filler association and its role in the nonlinear viscoelastic properties at large strain amplitudes were investigated.\n
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\n\n \n \n \n \n \n \n Easily fabricated Ag doped TiO2 nanorods for photo-catalytic applications.\n \n \n \n \n\n\n \n Nair, A. K.; Rajendragiri, A. G.; Santhosh, S.; and Kalarikkal, N.\n\n\n \n\n\n\n
AIP Conference Proceedings, 2115(1): 030122. July 2019.\n
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Paper\n \n \n\n \n \n doi\n \n \n\n \n link\n \n \n\n bibtex\n \n\n \n \n \n abstract \n \n\n \n\n \n \n \n \n \n \n \n\n \n \n \n\n\n\n
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@article{nair_easily_2019,\n\ttitle = {Easily fabricated {Ag} doped {TiO2} nanorods for photo-catalytic applications},\n\tvolume = {2115},\n\tissn = {0094-243X},\n\turl = {https://doi.org/10.1063/1.5112961},\n\tdoi = {10.1063/1.5112961},\n\tabstract = {A simple and effective hydrothermal approach for synthesizing Ag-doped TiO2 nanorods for photocatalytic application has been demonstrated. The structural, optical, morphological and photocatalytic properties of TiO2 nanorods and Ag doped TiO2 nanorods have been investigated. From the SEM results, it is confirmed that the prepared samples show vertically aligned rods like morphology. Furthermore, FTIR analysis shows a broad absorption band related to Ti-O vibration band. The samples TiO2 and Ag doped TiO2 nanorods exhibit enhanced photocatalytic efficiency towards degradation of Rh. B dye under visible light irradiation.},\n\tnumber = {1},\n\turldate = {2024-10-16},\n\tjournal = {AIP Conference Proceedings},\n\tauthor = {Nair, Anju K. and Rajendragiri, Ashishgiri Goswami and Santhosh, Shilpa and Kalarikkal, Nandakumar},\n\tmonth = jul,\n\tyear = {2019},\n\tpages = {030122},\n}\n\n\n\n
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\n A simple and effective hydrothermal approach for synthesizing Ag-doped TiO2 nanorods for photocatalytic application has been demonstrated. The structural, optical, morphological and photocatalytic properties of TiO2 nanorods and Ag doped TiO2 nanorods have been investigated. From the SEM results, it is confirmed that the prepared samples show vertically aligned rods like morphology. Furthermore, FTIR analysis shows a broad absorption band related to Ti-O vibration band. The samples TiO2 and Ag doped TiO2 nanorods exhibit enhanced photocatalytic efficiency towards degradation of Rh. B dye under visible light irradiation.\n
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\n\n \n \n \n \n \n \n DEVELOPMENTS AND PROSPECTS FOR IMPROVING THE PERFORMANCE OF DYE-SENSITIZED SOLAR CELLS - A REVIEW.\n \n \n \n \n\n\n \n Job, F.; Mathew, S.; and G, R.\n\n\n \n\n\n\n
International Journal of Research and Analytical Reviews, 6(2): 751–755. June 2019.\n
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@article{job_developments_2019,\n\ttitle = {{DEVELOPMENTS} {AND} {PROSPECTS} {FOR} {IMPROVING} {THE} {PERFORMANCE} {OF} {DYE}-{SENSITIZED} {SOLAR} {CELLS} - {A} {REVIEW}},\n\tvolume = {6},\n\tissn = {E-ISSN 2348-1269,P- ISSN 2349-5138},\n\turl = {https://ijrar.org/viewfull.php?&p_id=IJRAR19K5177},\n\tabstract = {UGC-CARE list, New UGC-CARE Reference List, UGC CARE Journals, ugc care list of journal, ugc care list, UGC Approved list, list of ugc approved journal, ugc approved journal,IJRAR - international Research Journal,IJRAR.ORG,Ijrar.org, International Journal of Research and Analytical Reviews (IJRAR) , UGC Approved journal, ugc approved,ugc, ugc certify, publish free of cost, free publication, UGC and ISSN Approved , International Peer Reviewed, Open Access Journal , e ISSN 2348 –1269, Print ISSN 2349-5138, ISSN: 2348 –1269, Impact Factor : 5.75 , E- journal, Low Cost INR 500, Free Publication},\n\tlanguage = {English},\n\tnumber = {2},\n\turldate = {2024-10-16},\n\tjournal = {International Journal of Research and Analytical Reviews},\n\tauthor = {Job, Feba and Mathew, Samuel and G, Reenamole},\n\tmonth = jun,\n\tyear = {2019},\n\tpages = {751--755},\n}\n\n\n\n
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\n UGC-CARE list, New UGC-CARE Reference List, UGC CARE Journals, ugc care list of journal, ugc care list, UGC Approved list, list of ugc approved journal, ugc approved journal,IJRAR - international Research Journal,IJRAR.ORG,Ijrar.org, International Journal of Research and Analytical Reviews (IJRAR) , UGC Approved journal, ugc approved,ugc, ugc certify, publish free of cost, free publication, UGC and ISSN Approved , International Peer Reviewed, Open Access Journal , e ISSN 2348 –1269, Print ISSN 2349-5138, ISSN: 2348 –1269, Impact Factor : 5.75 , E- journal, Low Cost INR 500, Free Publication\n
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\n\n \n \n \n \n \n \n Development of silver nanoparticles decorated graphene quantum dots for tailored applications.\n \n \n \n \n\n\n \n Mathew, J. A.; Nair, A. K.; and Kalarikkal, N.\n\n\n \n\n\n\n
AIP Conference Proceedings, 2115(1): 030078. July 2019.\n
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@article{mathew_development_2019,\n\ttitle = {Development of silver nanoparticles decorated graphene quantum dots for tailored applications},\n\tvolume = {2115},\n\tissn = {0094-243X},\n\turl = {https://doi.org/10.1063/1.5112917},\n\tdoi = {10.1063/1.5112917},\n\tabstract = {Silver nanoparticles (Ag NPs) decorated graphene quantum dots (GQDs) are synthesized through easy bottom-up approach with less number of chemical reagents. The as-synthesized Ag-GQDs were characterized via UV-Visible absorption Spectroscopy, Photoluminescence Spectroscopy, Time Resolved Fluorescence measurements, Raman Spectroscopy and Transmission Electron Microscopy for the realization of potential applications.},\n\tnumber = {1},\n\turldate = {2024-10-16},\n\tjournal = {AIP Conference Proceedings},\n\tauthor = {Mathew, Juby Alphonsa and Nair, Anju K. and Kalarikkal, Nandakumar},\n\tmonth = jul,\n\tyear = {2019},\n\tpages = {030078},\n}\n\n\n\n
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\n Silver nanoparticles (Ag NPs) decorated graphene quantum dots (GQDs) are synthesized through easy bottom-up approach with less number of chemical reagents. The as-synthesized Ag-GQDs were characterized via UV-Visible absorption Spectroscopy, Photoluminescence Spectroscopy, Time Resolved Fluorescence measurements, Raman Spectroscopy and Transmission Electron Microscopy for the realization of potential applications.\n
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\n\n \n \n \n \n \n \n A Study on Quasi – Groups Satisfying Partial Associative Law with Unique Right Unit.\n \n \n \n \n\n\n \n Thomas, M.\n\n\n \n\n\n\n
International Journal on Future Revolution in Computer Science & Communication Engineering, 5(12): 01 – 04. December 2019.\n
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@article{thomas_study_2019,\n\ttitle = {A {Study} on {Quasi} – {Groups} {Satisfying} {Partial} {Associative} {Law} with {Unique} {Right} {Unit}},\n\tvolume = {5},\n\tissn = {2454-4248},\n\turl = {http://www.ijfrcsce.org/},\n\tabstract = {A Quasi- group is an algebraic structure resembling a group in the sense that division is possible. Quasi –groups differ from a group, that they are not necessarily be associative. In this paper we make a study of quasi- groups which satisfy Partial associative law and have a right unit. It is seen that these Quasi –groups have properties very similar to ordinary groups.},\n\tlanguage = {en},\n\tnumber = {12},\n\tjournal = {International Journal on Future Revolution in Computer Science \\& Communication Engineering},\n\tauthor = {Thomas, Mini},\n\tmonth = dec,\n\tyear = {2019},\n\tpages = {01 -- 04},\n}\n\n\n\n
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\n A Quasi- group is an algebraic structure resembling a group in the sense that division is possible. Quasi –groups differ from a group, that they are not necessarily be associative. In this paper we make a study of quasi- groups which satisfy Partial associative law and have a right unit. It is seen that these Quasi –groups have properties very similar to ordinary groups.\n
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