Tuning photochromic ion channel blockers. …, Kienzler, M., Banghart, M., Fehrentz, T, & ... ACS chemical …, ACS Publications, 2011. Paper doi abstract bibtex Photochromic channel blockers provide a conceptually simple and convenient way to modulate neuronal activity with light. We have recently described a family of azobenzenes that function as tonic blockers of Kv channels but require UV-A light to unblock and need to be actively switched by toggling between two different wavelengths. We now introduce red-shifted compounds that fully operate in the visible region of the spectrum and quickly turn themselves off in the dark. Furthermore, we have developed a version that does not block …
@article{pop00228,
author = {… and MA Kienzler and MR Banghart and T Fehrentz and ...},
title = {Tuning photochromic ion channel blockers},
journal = {ACS chemical …},
publisher = {ACS Publications},
doi = {10.1021/cn200037p},
url = {https://pubs.acs.org/doi/abs/10.1021/cn200037p},
fulltext = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401033/},
related = {https://scholar.google.com/scholar?q=related:BQec2uAtlU8J:scholar.google.com/\&scioq=mourot+a+kienzler+ma+banghart+mr+fehrentz+t+huber+fm+stein+m+kramer+rh+trauner+d+tuning+photochromic+ion+channel+blockers+acs+chemical+neuroscience+2011+jun+%2224+2%22+9+%22536+43%22\&hl=en\&as_sdt=0,5\&as_vis=1},
year = {2011},
abstract = {Photochromic channel blockers provide a conceptually simple and convenient way to modulate neuronal activity with light. We have recently described a family of azobenzenes that function as tonic blockers of Kv channels but require UV-A light to unblock and need to be actively switched by toggling between two different wavelengths. We now introduce red-shifted compounds that fully operate in the visible region of the spectrum and quickly turn themselves off in the dark. Furthermore, we have developed a version that does not block …},
}
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