Synaptic computation. Abbott, L. & Regehr, W. G Nature, 431(7010):796-803, 2004. doi abstract bibtex Neurons are often considered to be the computational engines of the brain, with synapses acting solely as conveyers of information. But the diverse types of synaptic plasticity and the range of timescales over which they operate suggest that synapses have a more active role in information processing. Long-term changes in the transmission properties of synapses provide a physiological substrate for learning and memory, whereas short-term changes support a variety of computations. By expressing several forms of synaptic plasticity, a single neuron can convey an array of different signals to the neural circuit in which it operates.
@Article{Abbott2004,
author = {LF Abbott and Wade G Regehr},
journal = {Nature},
title = {Synaptic computation.},
year = {2004},
number = {7010},
pages = {796-803},
volume = {431},
abstract = {Neurons are often considered to be the computational engines of the
brain, with synapses acting solely as conveyers of information. But
the diverse types of synaptic plasticity and the range of timescales
over which they operate suggest that synapses have a more active
role in information processing. Long-term changes in the transmission
properties of synapses provide a physiological substrate for learning
and memory, whereas short-term changes support a variety of computations.
By expressing several forms of synaptic plasticity, a single neuron
can convey an array of different signals to the neural circuit in
which it operates.},
doi = {10.1038/nature03010},
groups = {Gain control},
keywords = {Animals, Attention, Brain, Decision Making, Face, Female, Haplorhini, Housing, Humans, Magnetic Resonance Imaging, Male, Models, Neurological, Pattern Recognition, Visual, Photic Stimulation, Prefrontal Cortex, Research Support, Non-U.S. Gov't, U.S. Gov't, P.H.S., Visual Perception, Choice Behavior, Cognition, Dopamine, Learning, Schizophrenia, Substance-Related Disorders, Generalization (Psychology), Motor Skills, Non-P.H.S., Nerve Net, Neuronal Plasticity, Perception, Cerebral Cortex, Memory, Neurons, Sound Localization, Synapses, Synaptic Transmission, 15483601},
}
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