Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis. Abdelwahab, M. T., Wasserman, S., Brust, J. C. M., Dheda, K., Wiesner, L., Gandhi, N. R., Warren, R. M., Sirgel, F. A, Meintjes, G., Maartens, G., & Denti, P. Antimicrobial Agents and Chemotherapy, 65(12):e01381–21, nov, 2021.
Paper doi abstract bibtex Linezolid is widely used for drug-resistant tuberculosis (DR-TB) but has a narrow therapeutic index. To inform dose optimization, we aimed to characterize the population pharmacokinetics of linezolid in South African participants with DR-TB and explore the effect of covariates, including HIV coinfection, on drug exposure.
@article{Abdelwahab2021a,
abstract = {Linezolid is widely used for drug-resistant tuberculosis (DR-TB) but has a narrow therapeutic index. To inform dose optimization, we aimed to characterize the population pharmacokinetics of linezolid in South African participants with DR-TB and explore the effect of covariates, including HIV coinfection, on drug exposure.},
author = {Abdelwahab, Mahmoud Tareq and Wasserman, Sean and Brust, James C. M. and Dheda, Keertan and Wiesner, Lubbe and Gandhi, Neel R. and Warren, Robin M. and Sirgel, Frederick A and Meintjes, Graeme and Maartens, Gary and Denti, Paolo},
doi = {10.1128/AAC.01381-21},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Abdelwahab et al. - 2021 - Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis.pdf:pdf;:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Abdelwahab et al. - 2021 - Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis(2).pdf:pdf},
issn = {0066-4804},
journal = {Antimicrobial Agents and Chemotherapy},
keywords = {OA,fund{\_}ack,original},
mendeley-tags = {OA,fund{\_}ack,original},
month = {nov},
number = {12},
pages = {e01381--21},
pmid = {34543098},
title = {{Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis}},
url = {https://journals.asm.org/doi/10.1128/AAC.01381-21},
volume = {65},
year = {2021}
}
Downloads: 0
{"_id":"Gpci4QzdWFEj9s37b","bibbaseid":"abdelwahab-wasserman-brust-dheda-wiesner-gandhi-warren-sirgel-etal-linezolidpopulationpharmacokineticsinsouthafricanadultswithdrugresistanttuberculosis-2021","author_short":["Abdelwahab, M. T.","Wasserman, S.","Brust, J. C. M.","Dheda, K.","Wiesner, L.","Gandhi, N. R.","Warren, R. M.","Sirgel, F. A","Meintjes, G.","Maartens, G.","Denti, P."],"bibdata":{"bibtype":"article","type":"article","abstract":"Linezolid is widely used for drug-resistant tuberculosis (DR-TB) but has a narrow therapeutic index. To inform dose optimization, we aimed to characterize the population pharmacokinetics of linezolid in South African participants with DR-TB and explore the effect of covariates, including HIV coinfection, on drug exposure.","author":[{"propositions":[],"lastnames":["Abdelwahab"],"firstnames":["Mahmoud","Tareq"],"suffixes":[]},{"propositions":[],"lastnames":["Wasserman"],"firstnames":["Sean"],"suffixes":[]},{"propositions":[],"lastnames":["Brust"],"firstnames":["James","C.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Dheda"],"firstnames":["Keertan"],"suffixes":[]},{"propositions":[],"lastnames":["Wiesner"],"firstnames":["Lubbe"],"suffixes":[]},{"propositions":[],"lastnames":["Gandhi"],"firstnames":["Neel","R."],"suffixes":[]},{"propositions":[],"lastnames":["Warren"],"firstnames":["Robin","M."],"suffixes":[]},{"propositions":[],"lastnames":["Sirgel"],"firstnames":["Frederick","A"],"suffixes":[]},{"propositions":[],"lastnames":["Meintjes"],"firstnames":["Graeme"],"suffixes":[]},{"propositions":[],"lastnames":["Maartens"],"firstnames":["Gary"],"suffixes":[]},{"propositions":[],"lastnames":["Denti"],"firstnames":["Paolo"],"suffixes":[]}],"doi":"10.1128/AAC.01381-21","file":":C$\\$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Abdelwahab et al. - 2021 - Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis.pdf:pdf;:C$\\$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Abdelwahab et al. - 2021 - Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis(2).pdf:pdf","issn":"0066-4804","journal":"Antimicrobial Agents and Chemotherapy","keywords":"OA,fund_ack,original","mendeley-tags":"OA,fund_ack,original","month":"nov","number":"12","pages":"e01381–21","pmid":"34543098","title":"Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis","url":"https://journals.asm.org/doi/10.1128/AAC.01381-21","volume":"65","year":"2021","bibtex":"@article{Abdelwahab2021a,\r\nabstract = {Linezolid is widely used for drug-resistant tuberculosis (DR-TB) but has a narrow therapeutic index. To inform dose optimization, we aimed to characterize the population pharmacokinetics of linezolid in South African participants with DR-TB and explore the effect of covariates, including HIV coinfection, on drug exposure.},\r\nauthor = {Abdelwahab, Mahmoud Tareq and Wasserman, Sean and Brust, James C. M. and Dheda, Keertan and Wiesner, Lubbe and Gandhi, Neel R. and Warren, Robin M. and Sirgel, Frederick A and Meintjes, Graeme and Maartens, Gary and Denti, Paolo},\r\ndoi = {10.1128/AAC.01381-21},\r\nfile = {:C$\\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Abdelwahab et al. - 2021 - Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis.pdf:pdf;:C$\\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Abdelwahab et al. - 2021 - Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis(2).pdf:pdf},\r\nissn = {0066-4804},\r\njournal = {Antimicrobial Agents and Chemotherapy},\r\nkeywords = {OA,fund{\\_}ack,original},\r\nmendeley-tags = {OA,fund{\\_}ack,original},\r\nmonth = {nov},\r\nnumber = {12},\r\npages = {e01381--21},\r\npmid = {34543098},\r\ntitle = {{Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis}},\r\nurl = {https://journals.asm.org/doi/10.1128/AAC.01381-21},\r\nvolume = {65},\r\nyear = {2021}\r\n}\r\n","author_short":["Abdelwahab, M. T.","Wasserman, S.","Brust, J. C. M.","Dheda, K.","Wiesner, L.","Gandhi, N. R.","Warren, R. M.","Sirgel, F. A","Meintjes, G.","Maartens, G.","Denti, P."],"key":"Abdelwahab2021a","id":"Abdelwahab2021a","bibbaseid":"abdelwahab-wasserman-brust-dheda-wiesner-gandhi-warren-sirgel-etal-linezolidpopulationpharmacokineticsinsouthafricanadultswithdrugresistanttuberculosis-2021","role":"author","urls":{"Paper":"https://journals.asm.org/doi/10.1128/AAC.01381-21"},"keyword":["OA","fund_ack","original"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://drive.google.com/uc?export=download&id=1-JLqZ7RwZ3VC2d6ErLGHAtOeMRS_7GCz","dataSources":["Krmt6gt9ktB2s6ARh","wrEvssexmuYudwQw9","9bX4N36CTXtCXNFMd","6GMFi5DCojy3jHY44"],"keywords":["oa","fund_ack","original"],"search_terms":["linezolid","population","pharmacokinetics","south","african","adults","drug","resistant","tuberculosis","abdelwahab","wasserman","brust","dheda","wiesner","gandhi","warren","sirgel","meintjes","maartens","denti"],"title":"Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis","year":2021}