Clinical Comparison of Two Photosensitizers for Oral Cavity Decontamination. Adad, H., R., Donato, R., Pratavieira, S., O., Grecco, C., Brugnera-Jú, A., Bagnato, V., S., & Kurachi, C. ![Clinical Comparison of Two Photosensitizers for Oral Cavity Decontamination [pdf]](https://bibbase.org/img/filetypes/pdf.svg "pdf")
Paper abstract bibtex Objective: In this study, we aim to compare the photodynamic inactivation (PDI) effects of two different photosensitizers (PS), Photogem Ò and Natural Curcumin, irradiated with light-emitted diodes (LED) at 630 and 450 nm, respectively. Background: The current antimicrobial mouthwash for oral hygiene has several draw-backs. In this context, PDI is an alternative technique to inactivate pathogenic microbes in mucosa and in periodontal tissue. Furthermore, there are numerous infectious diseases that may affect the oral cavity, moti-vating the use of PDI in dentistry. Methods: The volunteers (n = 50) were randomize separated into five experimental groups (n = 5) for each PS: water control, PS control, light control, and two PS concentrations (25 and 100 mg/L). Each patient underwent mouthwash solution containing the PS before illumination procedure that was performed with an LED device. For microbial decontamination evaluation, the saliva was collected three times: before (T0), immediately after (T1), and 24 h after the illumination procedure (T2). After that, the difference between the colony forming units (CFU) for each volunteer was compared. Results: The results show that regardless of PS and treatment applied, there was microbial reduction immediately after PDI, however, after 24 h only Natural Curcumin still presents a reduction. For Photogem after 24 h, the microorganism returns to the original CFU. Conclusions: Immediately after PDI, both PS have the same efficiency, nevertheless the Natural Curcumin still has an efficacy after 24 h and also is a more viable photosensitizer. In addition, the results indicate that PDI can be a promised technique used for microbial reducing for the oral cavity.
@article{
title = {Clinical Comparison of Two Photosensitizers for Oral Cavity Decontamination},
type = {article},
identifiers = {[object Object]},
keywords = {clinical,curcuminoids,hematoporphyrin,in vivo,photodynamic inactivation},
id = {b37e068d-29bf-3863-b933-89ba2923ec31},
created = {2017-01-14T15:53:44.000Z},
file_attached = {true},
profile_id = {9a94bc2c-179e-361a-8ebd-41a00966522f},
last_modified = {2019-01-04T17:27:45.518Z},
read = {false},
starred = {false},
authored = {true},
confirmed = {true},
hidden = {false},
private_publication = {false},
abstract = {Objective: In this study, we aim to compare the photodynamic inactivation (PDI) effects of two different photosensitizers (PS), Photogem Ò and Natural Curcumin, irradiated with light-emitted diodes (LED) at 630 and 450 nm, respectively. Background: The current antimicrobial mouthwash for oral hygiene has several draw-backs. In this context, PDI is an alternative technique to inactivate pathogenic microbes in mucosa and in periodontal tissue. Furthermore, there are numerous infectious diseases that may affect the oral cavity, moti-vating the use of PDI in dentistry. Methods: The volunteers (n = 50) were randomize separated into five experimental groups (n = 5) for each PS: water control, PS control, light control, and two PS concentrations (25 and 100 mg/L). Each patient underwent mouthwash solution containing the PS before illumination procedure that was performed with an LED device. For microbial decontamination evaluation, the saliva was collected three times: before (T0), immediately after (T1), and 24 h after the illumination procedure (T2). After that, the difference between the colony forming units (CFU) for each volunteer was compared. Results: The results show that regardless of PS and treatment applied, there was microbial reduction immediately after PDI, however, after 24 h only Natural Curcumin still presents a reduction. For Photogem after 24 h, the microorganism returns to the original CFU. Conclusions: Immediately after PDI, both PS have the same efficiency, nevertheless the Natural Curcumin still has an efficacy after 24 h and also is a more viable photosensitizer. In addition, the results indicate that PDI can be a promised technique used for microbial reducing for the oral cavity.},
bibtype = {article},
author = {Adad, Hé Rica and Donato, Ricci and Pratavieira, Sebastiã O and Grecco, Clovis and Brugnera-Jú, Aldo and Bagnato, Vanderlei Salvador and Kurachi, Cristina}
}
Downloads: 0
{"_id":"R4ywLwY3gnX8CNRK4","bibbaseid":"adad-donato-pratavieira-grecco-brugneraj-bagnato-kurachi-clinicalcomparisonoftwophotosensitizersfororalcavitydecontamination","authorIDs":["5df909d02e8c31df010000c9"],"author_short":["Adad, H., R.","Donato, R.","Pratavieira, S., O.","Grecco, C.","Brugnera-Jú, A.","Bagnato, V., S.","Kurachi, C."],"bibdata":{"title":"Clinical Comparison of Two Photosensitizers for Oral Cavity Decontamination","type":"article","identifiers":"[object Object]","keywords":"clinical,curcuminoids,hematoporphyrin,in vivo,photodynamic inactivation","id":"b37e068d-29bf-3863-b933-89ba2923ec31","created":"2017-01-14T15:53:44.000Z","file_attached":"true","profile_id":"9a94bc2c-179e-361a-8ebd-41a00966522f","last_modified":"2019-01-04T17:27:45.518Z","read":false,"starred":false,"authored":"true","confirmed":"true","hidden":false,"private_publication":false,"abstract":"Objective: In this study, we aim to compare the photodynamic inactivation (PDI) effects of two different photosensitizers (PS), Photogem Ò and Natural Curcumin, irradiated with light-emitted diodes (LED) at 630 and 450 nm, respectively. Background: The current antimicrobial mouthwash for oral hygiene has several draw-backs. In this context, PDI is an alternative technique to inactivate pathogenic microbes in mucosa and in periodontal tissue. Furthermore, there are numerous infectious diseases that may affect the oral cavity, moti-vating the use of PDI in dentistry. Methods: The volunteers (n = 50) were randomize separated into five experimental groups (n = 5) for each PS: water control, PS control, light control, and two PS concentrations (25 and 100 mg/L). Each patient underwent mouthwash solution containing the PS before illumination procedure that was performed with an LED device. For microbial decontamination evaluation, the saliva was collected three times: before (T0), immediately after (T1), and 24 h after the illumination procedure (T2). After that, the difference between the colony forming units (CFU) for each volunteer was compared. Results: The results show that regardless of PS and treatment applied, there was microbial reduction immediately after PDI, however, after 24 h only Natural Curcumin still presents a reduction. For Photogem after 24 h, the microorganism returns to the original CFU. Conclusions: Immediately after PDI, both PS have the same efficiency, nevertheless the Natural Curcumin still has an efficacy after 24 h and also is a more viable photosensitizer. In addition, the results indicate that PDI can be a promised technique used for microbial reducing for the oral cavity.","bibtype":"article","author":"Adad, Hé Rica and Donato, Ricci and Pratavieira, Sebastiã O and Grecco, Clovis and Brugnera-Jú, Aldo and Bagnato, Vanderlei Salvador and Kurachi, Cristina","bibtex":"@article{\n title = {Clinical Comparison of Two Photosensitizers for Oral Cavity Decontamination},\n type = {article},\n identifiers = {[object Object]},\n keywords = {clinical,curcuminoids,hematoporphyrin,in vivo,photodynamic inactivation},\n id = {b37e068d-29bf-3863-b933-89ba2923ec31},\n created = {2017-01-14T15:53:44.000Z},\n file_attached = {true},\n profile_id = {9a94bc2c-179e-361a-8ebd-41a00966522f},\n last_modified = {2019-01-04T17:27:45.518Z},\n read = {false},\n starred = {false},\n authored = {true},\n confirmed = {true},\n hidden = {false},\n private_publication = {false},\n abstract = {Objective: In this study, we aim to compare the photodynamic inactivation (PDI) effects of two different photosensitizers (PS), Photogem Ò and Natural Curcumin, irradiated with light-emitted diodes (LED) at 630 and 450 nm, respectively. Background: The current antimicrobial mouthwash for oral hygiene has several draw-backs. In this context, PDI is an alternative technique to inactivate pathogenic microbes in mucosa and in periodontal tissue. Furthermore, there are numerous infectious diseases that may affect the oral cavity, moti-vating the use of PDI in dentistry. Methods: The volunteers (n = 50) were randomize separated into five experimental groups (n = 5) for each PS: water control, PS control, light control, and two PS concentrations (25 and 100 mg/L). Each patient underwent mouthwash solution containing the PS before illumination procedure that was performed with an LED device. For microbial decontamination evaluation, the saliva was collected three times: before (T0), immediately after (T1), and 24 h after the illumination procedure (T2). After that, the difference between the colony forming units (CFU) for each volunteer was compared. Results: The results show that regardless of PS and treatment applied, there was microbial reduction immediately after PDI, however, after 24 h only Natural Curcumin still presents a reduction. For Photogem after 24 h, the microorganism returns to the original CFU. Conclusions: Immediately after PDI, both PS have the same efficiency, nevertheless the Natural Curcumin still has an efficacy after 24 h and also is a more viable photosensitizer. In addition, the results indicate that PDI can be a promised technique used for microbial reducing for the oral cavity.},\n bibtype = {article},\n author = {Adad, Hé Rica and Donato, Ricci and Pratavieira, Sebastiã O and Grecco, Clovis and Brugnera-Jú, Aldo and Bagnato, Vanderlei Salvador and Kurachi, Cristina}\n}","author_short":["Adad, H., R.","Donato, R.","Pratavieira, S., O.","Grecco, C.","Brugnera-Jú, A.","Bagnato, V., S.","Kurachi, C."],"urls":{"Paper":"https://bibbase.org/service/mendeley/9a94bc2c-179e-361a-8ebd-41a00966522f/file/26a356c5-98cb-707b-2e1c-223c8429e99e/Clinical_Comparison_of_Two_Photosensitizers_for_Oral_Cavity_Decontamination.pdf.pdf"},"bibbaseid":"adad-donato-pratavieira-grecco-brugneraj-bagnato-kurachi-clinicalcomparisonoftwophotosensitizersfororalcavitydecontamination","role":"author","keyword":["clinical","curcuminoids","hematoporphyrin","in vivo","photodynamic inactivation"],"downloads":0,"html":""},"bibtype":"article","creationDate":"2019-12-17T17:01:04.260Z","downloads":0,"keywords":["clinical","curcuminoids","hematoporphyrin","in vivo","photodynamic inactivation"],"search_terms":["clinical","comparison","two","photosensitizers","oral","cavity","decontamination","adad","donato","pratavieira","grecco","brugnera-jú","bagnato","kurachi"],"title":"Clinical Comparison of Two Photosensitizers for Oral Cavity Decontamination","year":null}