Characterization of Antibody-Binding Sites on Proteins: Development of a Knowledgebase and Its Applications in Improving Epitope Prediction. A.D. Ghate, B.U. Bhagwat, S.G. Bhosle, S.M. Gadepalli, & U.D. Kulkarni-Kale Protein and Peptide Letters, 14(6):531--535, June, 2007. doi abstract bibtex Immunoinformatics provides tools for reverse vaccinology and encompasses development of knowledge bases and algorithms for prediction of epitopes. AgAbDb, a database archiving molecular interactions of antigen-antibody cocrystal structures, has been developed (http://202.41.70.51:8080/agabdb2/). Analyses of antibody-binding sites on proteins helped to fine-tune the parameters for prediction of sequential and conformational B-cell epitopes.
@article{a.d._ghate_characterization_2007,
title = {Characterization of {Antibody}-{Binding} {Sites} on {Proteins}: {Development} of a {Knowledgebase} and {Its} {Applications} in {Improving} {Epitope} {Prediction}},
volume = {14},
shorttitle = {Characterization of {Antibody}-{Binding} {Sites} on {Proteins}},
doi = {10.2174/092986607780989921},
abstract = {Immunoinformatics provides tools for reverse vaccinology and encompasses development of knowledge bases and algorithms for prediction of epitopes. AgAbDb, a database archiving molecular interactions of antigen-antibody cocrystal structures, has been developed (http://202.41.70.51:8080/agabdb2/). Analyses of antibody-binding sites on proteins helped to fine-tune the parameters for prediction of sequential and conformational B-cell epitopes.},
number = {6},
journal = {Protein and Peptide Letters},
author = {{A.D. Ghate} and {B.U. Bhagwat} and {S.G. Bhosle} and {S.M. Gadepalli} and {U.D. Kulkarni-Kale}},
month = jun,
year = {2007},
keywords = {Antigenantibody Interactions, B-Cell Epitope Prediction, Conformational or Discontinuous Epitope, Derived Database, Immunoinformatics, bioinformatics},
pages = {531--535}
}
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