Molecular Biophysics Database (MBDB) makes raw measurements findable and reusable. Agerschou, E. D., Prchalová, T., Šimek, M., Malý, M., Stránský, J., Strnad, M., Santisteban-Veiga, A., Williams, M. A., Sabín, J., & Dohnálek, J. European Biophysics Journal, August, 2025.
Molecular Biophysics Database (MBDB) makes raw measurements findable and reusable [link]Paper  doi  abstract   bibtex   
Open science is now established as an important paradigm for publicly funded research. The main principle being that to ensure best use of research data and integrity of the scientific process the information from experiments should be made widely and freely available. However, dedicated technical infrastructure to enable useful access to comprehensive experimental information in molecular biophysics is lacking, in particular in regard to repositories for raw measurement data. The Molecular Biophysics Database (MBDB) was created to fill this gap. The MBDB provides a common and extensible framework to store and access raw measurement data from a growing number of biophysical methods, currently including bio-layer interferometry, isothermal titration calorimetry, surface plasmon resonance, and microscale thermophoresis, with additional methods planned for the future. Alongside the raw measurement data from these methods, a rich set of metadata to enable data reuse is captured in accordance with the FAIR data management principles. An overview of the data models and technologies that were used to create the MBDB is presented here.
@article{agerschou_molecular_2025,
	title = {Molecular {Biophysics} {Database} ({MBDB}) makes raw measurements findable and reusable},
	issn = {1432-1017},
	url = {https://doi.org/10.1007/s00249-025-01789-1},
	doi = {10.1007/s00249-025-01789-1},
	abstract = {Open science is now established as an important paradigm for publicly funded research. The main principle being that to ensure best use of research data and integrity of the scientific process the information from experiments should be made widely and freely available. However, dedicated technical infrastructure to enable useful access to comprehensive experimental information in molecular biophysics is lacking, in particular in regard to repositories for raw measurement data. The Molecular Biophysics Database (MBDB) was created to fill this gap. The MBDB provides a common and extensible framework to store and access raw measurement data from a growing number of biophysical methods, currently including bio-layer interferometry, isothermal titration calorimetry, surface plasmon resonance, and microscale thermophoresis, with additional methods planned for the future. Alongside the raw measurement data from these methods, a rich set of metadata to enable data reuse is captured in accordance with the FAIR data management principles. An overview of the data models and technologies that were used to create the MBDB is presented here.},
	language = {en},
	urldate = {2025-08-15},
	journal = {European Biophysics Journal},
	author = {Agerschou, Emil Dandanell and Prchalová, Terezie and Šimek, Miroslav and Malý, Michal and Stránský, Jan and Strnad, Michal and Santisteban-Veiga, Andrea and Williams, Mark A. and Sabín, Juan and Dohnálek, Jan},
	month = aug,
	year = {2025},
	keywords = {Database, FAIR principles, Metadata model, Molecular biophysics, Raw data, Repository},
}

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