In-Vitro Anti Inflammatory Activity of Salix Caprea Linn. (Goat Willow) by HRBC Membrane Stabilization Method. Ahmed, A., Shah, W. A., Akbar, S., Kumar, D., Kumar, V., & Younis, M. 4(4):1067–1068.
abstract   bibtex   
Ethnopharmacological Relevance: Salix caprea L. is belonging to family Salicaceae and commonly known as goat willow. Salix caprea is a common species of willow native to Europe and western and central Asia. It is a folkloric medicinal plant used to treat rheumatoid arthritis, malaria, various hemorrhages, gout, neuralgia and intestinal diseases. It is also used as an antipyretic, analgesic, antibacterial, haemostatic, sedative and anthelmintic agent. Aim of study: The present work aims to evaluate the anti inflammatory activity of salix caprea flower by HRBC membrane stabilization method. Materials and methods: Flowers of Salix caprea were powdered and successively extracted with petroleum ether, ethyl acetate, methanol, hydro alcohol and aqueous extracts. These extracts were subjected to identify the anti-inflammatory potential of Salix caprea by HRBC membrane stabilization method. Results: The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure for the anti inflammatory activity. The percentage protection of petroleum ether, ethyl acetate, methanol, hydroalcohol and aqueous extracts were 45.57, 61.10, 66.79, 60.49, 68.39\,% at 400μg/ml respectively and Diclofenac sodium hold the percentage protection 77.39\,% at 200μg/ml. Conclusion: Salix caprea holds the promising anti-inflammatory activity. The hydroalcohalic, methanolic extracts showed most and aqueous, ethyl acetate extracts showed intermediate while petroleum ether extract showed least percentage protection as compared to Diclofenac sodium.
@article{ahmedInvitroInflammatoryActivity2011,
  title = {In-Vitro Anti Inflammatory Activity of {{Salix}} Caprea {{Linn}}. (Goat Willow) by {{HRBC}} Membrane Stabilization Method},
  author = {Ahmed, Ajaz and Shah, Wajahat A. and Akbar, Seema and Kumar, Dinesh and Kumar, Vijender and Younis, Mohammad},
  date = {2011},
  journaltitle = {Journal of Pharmacy Research},
  volume = {4},
  pages = {1067--1068},
  issn = {0974-6943},
  abstract = {Ethnopharmacological Relevance: Salix caprea L. is belonging to family Salicaceae and commonly known as goat willow. Salix caprea is a common species of willow native to Europe and western and central Asia. It is a folkloric medicinal plant used to treat rheumatoid arthritis, malaria, various hemorrhages, gout, neuralgia and intestinal diseases. It is also used as an antipyretic, analgesic, antibacterial, haemostatic, sedative and anthelmintic agent. Aim of study: The present work aims to evaluate the anti inflammatory activity of salix caprea flower by HRBC membrane stabilization method. Materials and methods: Flowers of Salix caprea were powdered and successively extracted with petroleum ether, ethyl acetate, methanol, hydro alcohol and aqueous extracts. These extracts were subjected to identify the anti-inflammatory potential of Salix caprea by HRBC membrane stabilization method. Results: The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure for the anti inflammatory activity. The percentage protection of petroleum ether, ethyl acetate, methanol, hydroalcohol and aqueous extracts were 45.57, 61.10, 66.79, 60.49, 68.39\,\% at 400μg/ml respectively and Diclofenac sodium hold the percentage protection 77.39\,\% at 200μg/ml. Conclusion: Salix caprea holds the promising anti-inflammatory activity. The hydroalcohalic, methanolic extracts showed most and aqueous, ethyl acetate extracts showed intermediate while petroleum ether extract showed least percentage protection as compared to Diclofenac sodium.},
  keywords = {*imported-from-citeulike-INRMM,~INRMM-MiD:c-13506744,pharmacology,physiology,salix-caprea},
  number = {4}
}

Downloads: 0