Assessment of the Efficacy of Tranexamic Acid Solution 5% in the Treatment of Melasma in Patients of South Asian Descent. Akhtar, N., Shah, R. R., Waqas, N., Jasti, S., Sharif, S., Shah, A., Abbasi, H. H., & Rao, B. Cutis, 112(4):187–191.E4, October, 2023. doi abstract bibtex Melasma is a common dermatologic condition affecting all skin types. Increasing rates of melasma warrant identification of a reliable topical treatment. In recent years, off-label tranexamic acid (TA) has emerged as a potential treatment of melasma. Although the mechanism of action remains unclear, it is thought that TA inhibits melanin synthesis by blocking the interaction between melanocytes and keratinocytes while reversing the abnormal dermal changes associated with melasma. Our study assessed the efficacy of TA solution 5% for the treatment of melasma in patients with darker skin types.
@article{akhtar_assessment_2023,
title = {Assessment of the {Efficacy} of {Tranexamic} {Acid} {Solution} 5\% in the {Treatment} of {Melasma} in {Patients} of {South} {Asian} {Descent}},
volume = {112},
issn = {2326-6929},
doi = {10.12788/cutis.0869},
abstract = {Melasma is a common dermatologic condition affecting all skin types. Increasing rates of melasma warrant identification of a reliable topical treatment. In recent years, off-label tranexamic acid (TA) has emerged as a potential treatment of melasma. Although the mechanism of action remains unclear, it is thought that TA inhibits melanin synthesis by blocking the interaction between melanocytes and keratinocytes while reversing the abnormal dermal changes associated with melasma. Our study assessed the efficacy of TA solution 5\% for the treatment of melasma in patients with darker skin types.},
language = {eng},
number = {4},
journal = {Cutis},
author = {Akhtar, Nazia and Shah, Rohan R. and Waqas, Nadia and Jasti, Shravya and Sharif, Shawana and Shah, Amar and Abbasi, Hina H. and Rao, Babar},
month = oct,
year = {2023},
pmid = {37988305},
keywords = {Administration, Oral, Administration, Topical, Humans, Melanosis, South Asian People, Tranexamic Acid, Treatment Outcome},
pages = {187--191.E4},
}