Direct selection of human genomic loci by microarray hybridization. Albert, T J, Molla, M N, Muzny, D M, Nazareth, L, Wheeler, D, Song, X, Richmond, T A, Middle, C M, Rodesch, M J, Packard, C J, Weinstock, G M, & Gibbs, R A Nat Methods, 4(11):903-905, November, 2007. ![Direct selection of human genomic loci by microarray hybridization [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex We applied high-density microarrays to the enrichment of specific sequences from the human genome for high-throughput sequencing. After capture of 6,726 approximately 500-base 'exon' segments, and of 'locus-specific' regions ranging in size from 200 kb to 5 Mb, followed by sequencing on a 454 Life Sciences FLX sequencer, most sequence reads represented selection targets. These direct selection methods supersede multiplex PCR for the large-scale analysis of genomic regions.
@article{Albert:2007:Nat-Methods:17934467,
abstract = {We applied high-density microarrays to the enrichment of specific sequences from the human genome for high-throughput sequencing. After capture of 6,726 approximately 500-base 'exon' segments, and of 'locus-specific' regions ranging in size from 200 kb to 5 Mb, followed by sequencing on a 454 Life Sciences FLX sequencer, most sequence reads represented selection targets. These direct selection methods supersede multiplex PCR for the large-scale analysis of genomic regions.},
added-at = {2017-10-24T23:02:30.000+0200},
author = {Albert, T J and Molla, M N and Muzny, D M and Nazareth, L and Wheeler, D and Song, X and Richmond, T A and Middle, C M and Rodesch, M J and Packard, C J and Weinstock, G M and Gibbs, R A},
biburl = {https://www.bibsonomy.org/bibtex/24371cb60010243774472c970ec5f7b79/marcsaric},
description = {Direct selection of human genomic loci by microarray hybridization. - PubMed - NCBI},
doi = {10.1038/nmeth1111},
interhash = {3838d43f6a2a163dc712aa407a454035},
intrahash = {4371cb60010243774472c970ec5f7b79},
journal = {Nat Methods},
keywords = {enrichment exome wes SHOULDREAD sequencing},
month = nov,
number = 11,
pages = {903-905},
pmid = {17934467},
timestamp = {2017-10-24T23:03:01.000+0200},
title = {Direct selection of human genomic loci by microarray hybridization},
url = {https://www.ncbi.nlm.nih.gov/pubmed/17934467},
volume = 4,
year = 2007
}
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