@article{ali_organohalogenated_2013,
	title = {Organohalogenated contaminants ({OHCs}) in the serum and hair of pet cats and dogs: biosentinels of indoor pollution.},
	volume = {449},
	issn = {1879-1026},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/23403100},
	doi = {10.1016/j.scitotenv.2013.01.037},
	abstract = {Concentrations of different classes of organohalogenated contaminants (OHCs) viz., polybrominated diphenyl ethers (PBDEs), novel brominated flame retardants (NBFRs), bromophenols (BPs), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs) and their metabolites were determined in cat and dog serum and hair samples from Pakistan. The major DDT metabolite, p,p'-DDE, was the major OHC in cat serum (N=20) and ranged between 1 and 2150 ng/g lipid weight (lw). p,p'-DDE was not detected in dog serum (N=16). In contrary to other OHCs, levels of ∑HO-PCBs were significantly higher in dog serum (median=6.0 ng/g lw) than cat serum (median=2.2 ng/g lw). Levels of most OHCs were significantly higher (p{\textbackslash}textless0.05) in cat serum than those found in human serum from the same region, in particular for ∑PBDEs (ranged 1-1280 ng/g lw). Significantly lower levels of OCPs (p{\textbackslash}textless0.05) were detected in dog serum than in human serum. The concentrations of ∑BPs were seven times higher in cat serum (median 112 ng/g lw) than dog serum (median 16 ng/g lw). To the best of our knowledge, this is the first time that NBFRs, e.g. 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE), decabromodiphenylethane (DBDPE), and bis(2-ethylhexyl)-3,4,5,6-tetrabromophthalate (TBPH), were detected in cat and dog's hair. BTBPE had the highest detection frequency (30\%) in the serum samples. In cat and dog hair samples, the order of importance of OHCs was ∑OCPs{\textbackslash}textgreater∑NBFRs{\textbackslash}textgreater∑PBDEs{\textbackslash}textgreater∑PCB, with the highest concentrations being around 38 ng/g hair. In paired hair-serum cat samples (N=12), ∑DDTs (r=0.65, p=0.001) were significantly correlated, while for all other OHCs no significant correlations (p{\textbackslash}textless0.001) were observed in both cats and dogs. Our findings on both hair and serum samples suggested that pet dogs do not bioaccumulate DDTs. Our results are also in agreement with the hypothesis that pets may serve as biosentinels for indoor pollution. This is the first study to document the presence of OHCs in pets from Pakistan and provides baseline information for future monitoring of OHCs in pets.},
	journal = {The Science of the total environment},
	author = {Ali, Nadeem and Malik, Riffat Naseem and Mehdi, Toufeer and Eqani, Syed Ali Musstjab Akber Shah and Javeed, Aqeel and Neels, Hugo and Covaci, Adrian},
	month = apr,
	year = {2013},
	pmid = {23403100},
	keywords = {Flame retardants},
	pages = {29--36},
}

{"_id":"7oif8nPyKwMrGoqoz","bibbaseid":"ali-malik-mehdi-eqani-javeed-neels-covaci-organohalogenatedcontaminantsohcsintheserumandhairofpetcatsanddogsbiosentinelsofindoorpollution-2013","author_short":["Ali, N.","Malik, R. N.","Mehdi, T.","Eqani, S. A. M. A. S.","Javeed, A.","Neels, H.","Covaci, A."],"bibdata":{"bibtype":"article","type":"article","title":"Organohalogenated contaminants (OHCs) in the serum and hair of pet cats and dogs: biosentinels of indoor pollution.","volume":"449","issn":"1879-1026","url":"http://www.ncbi.nlm.nih.gov/pubmed/23403100","doi":"10.1016/j.scitotenv.2013.01.037","abstract":"Concentrations of different classes of organohalogenated contaminants (OHCs) viz., polybrominated diphenyl ethers (PBDEs), novel brominated flame retardants (NBFRs), bromophenols (BPs), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs) and their metabolites were determined in cat and dog serum and hair samples from Pakistan. The major DDT metabolite, p,p'-DDE, was the major OHC in cat serum (N=20) and ranged between 1 and 2150 ng/g lipid weight (lw). p,p'-DDE was not detected in dog serum (N=16). In contrary to other OHCs, levels of ∑HO-PCBs were significantly higher in dog serum (median=6.0 ng/g lw) than cat serum (median=2.2 ng/g lw). Levels of most OHCs were significantly higher (p\\textless0.05) in cat serum than those found in human serum from the same region, in particular for ∑PBDEs (ranged 1-1280 ng/g lw). Significantly lower levels of OCPs (p\\textless0.05) were detected in dog serum than in human serum. The concentrations of ∑BPs were seven times higher in cat serum (median 112 ng/g lw) than dog serum (median 16 ng/g lw). To the best of our knowledge, this is the first time that NBFRs, e.g. 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE), decabromodiphenylethane (DBDPE), and bis(2-ethylhexyl)-3,4,5,6-tetrabromophthalate (TBPH), were detected in cat and dog's hair. BTBPE had the highest detection frequency (30%) in the serum samples. In cat and dog hair samples, the order of importance of OHCs was ∑OCPs\\textgreater∑NBFRs\\textgreater∑PBDEs\\textgreater∑PCB, with the highest concentrations being around 38 ng/g hair. In paired hair-serum cat samples (N=12), ∑DDTs (r=0.65, p=0.001) were significantly correlated, while for all other OHCs no significant correlations (p\\textless0.001) were observed in both cats and dogs. Our findings on both hair and serum samples suggested that pet dogs do not bioaccumulate DDTs. Our results are also in agreement with the hypothesis that pets may serve as biosentinels for indoor pollution. This is the first study to document the presence of OHCs in pets from Pakistan and provides baseline information for future monitoring of OHCs in pets.","journal":"The Science of the total environment","author":[{"propositions":[],"lastnames":["Ali"],"firstnames":["Nadeem"],"suffixes":[]},{"propositions":[],"lastnames":["Malik"],"firstnames":["Riffat","Naseem"],"suffixes":[]},{"propositions":[],"lastnames":["Mehdi"],"firstnames":["Toufeer"],"suffixes":[]},{"propositions":[],"lastnames":["Eqani"],"firstnames":["Syed","Ali","Musstjab","Akber","Shah"],"suffixes":[]},{"propositions":[],"lastnames":["Javeed"],"firstnames":["Aqeel"],"suffixes":[]},{"propositions":[],"lastnames":["Neels"],"firstnames":["Hugo"],"suffixes":[]},{"propositions":[],"lastnames":["Covaci"],"firstnames":["Adrian"],"suffixes":[]}],"month":"April","year":"2013","pmid":"23403100","keywords":"Flame retardants","pages":"29–36","bibtex":"@article{ali_organohalogenated_2013,\n\ttitle = {Organohalogenated contaminants ({OHCs}) in the serum and hair of pet cats and dogs: biosentinels of indoor pollution.},\n\tvolume = {449},\n\tissn = {1879-1026},\n\turl = {http://www.ncbi.nlm.nih.gov/pubmed/23403100},\n\tdoi = {10.1016/j.scitotenv.2013.01.037},\n\tabstract = {Concentrations of different classes of organohalogenated contaminants (OHCs) viz., polybrominated diphenyl ethers (PBDEs), novel brominated flame retardants (NBFRs), bromophenols (BPs), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs) and their metabolites were determined in cat and dog serum and hair samples from Pakistan. The major DDT metabolite, p,p'-DDE, was the major OHC in cat serum (N=20) and ranged between 1 and 2150 ng/g lipid weight (lw). p,p'-DDE was not detected in dog serum (N=16). In contrary to other OHCs, levels of ∑HO-PCBs were significantly higher in dog serum (median=6.0 ng/g lw) than cat serum (median=2.2 ng/g lw). Levels of most OHCs were significantly higher (p{\\textbackslash}textless0.05) in cat serum than those found in human serum from the same region, in particular for ∑PBDEs (ranged 1-1280 ng/g lw). Significantly lower levels of OCPs (p{\\textbackslash}textless0.05) were detected in dog serum than in human serum. The concentrations of ∑BPs were seven times higher in cat serum (median 112 ng/g lw) than dog serum (median 16 ng/g lw). To the best of our knowledge, this is the first time that NBFRs, e.g. 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE), decabromodiphenylethane (DBDPE), and bis(2-ethylhexyl)-3,4,5,6-tetrabromophthalate (TBPH), were detected in cat and dog's hair. BTBPE had the highest detection frequency (30\\%) in the serum samples. In cat and dog hair samples, the order of importance of OHCs was ∑OCPs{\\textbackslash}textgreater∑NBFRs{\\textbackslash}textgreater∑PBDEs{\\textbackslash}textgreater∑PCB, with the highest concentrations being around 38 ng/g hair. In paired hair-serum cat samples (N=12), ∑DDTs (r=0.65, p=0.001) were significantly correlated, while for all other OHCs no significant correlations (p{\\textbackslash}textless0.001) were observed in both cats and dogs. Our findings on both hair and serum samples suggested that pet dogs do not bioaccumulate DDTs. Our results are also in agreement with the hypothesis that pets may serve as biosentinels for indoor pollution. This is the first study to document the presence of OHCs in pets from Pakistan and provides baseline information for future monitoring of OHCs in pets.},\n\tjournal = {The Science of the total environment},\n\tauthor = {Ali, Nadeem and Malik, Riffat Naseem and Mehdi, Toufeer and Eqani, Syed Ali Musstjab Akber Shah and Javeed, Aqeel and Neels, Hugo and Covaci, Adrian},\n\tmonth = apr,\n\tyear = {2013},\n\tpmid = {23403100},\n\tkeywords = {Flame retardants},\n\tpages = {29--36},\n}\n\n\n\n","author_short":["Ali, N.","Malik, R. N.","Mehdi, T.","Eqani, S. A. M. A. S.","Javeed, A.","Neels, H.","Covaci, A."],"key":"ali_organohalogenated_2013","id":"ali_organohalogenated_2013","bibbaseid":"ali-malik-mehdi-eqani-javeed-neels-covaci-organohalogenatedcontaminantsohcsintheserumandhairofpetcatsanddogsbiosentinelsofindoorpollution-2013","role":"author","urls":{"Paper":"http://www.ncbi.nlm.nih.gov/pubmed/23403100"},"keyword":["Flame retardants"],"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"http://bibbase.org/zotero/mdedeo","dataSources":["SSfxPwd7XbkRtnZ9f"],"keywords":["flame retardants"],"search_terms":["organohalogenated","contaminants","ohcs","serum","hair","pet","cats","dogs","biosentinels","indoor","pollution","ali","malik","mehdi","eqani","javeed","neels","covaci"],"title":"Organohalogenated contaminants (OHCs) in the serum and hair of pet cats and dogs: biosentinels of indoor pollution.","year":2013}