Microbial function and genital inflammation in young South African women at high risk of HIV infection. Alisoltani, A., Manhanzva, M. T., Potgieter, M., Balle, C., Bell, L., Ross, E., Iranzadeh, A., du Plessis, M., Radzey, N., McDonald, Z., Calder, B., Allali, I., Mulder, N., Dabee, S., Barnabas, S., Gamieldien, H., Godzik, A., Blackburn, J. M., Tabb, D. L., Bekker, L., Jaspan, H. B., Passmore, J. S., & Masson, L. Microbiome, 8(1):165, BioMed Central, dec, 2020. ![Microbial function and genital inflammation in young South African women at high risk of HIV infection [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Background: Female genital tract (FGT) inflammation is an important risk factor for HIV acquisition. The FGT microbiome is closely associated with inflammatory profile; however, the relative importance of microbial activities has not been established. Since proteins are key elements representing actual microbial functions, this study utilized metaproteomics to evaluate the relationship between FGT microbial function and inflammation in 113 young and adolescent South African women at high risk of HIV infection. Women were grouped as having low, medium, or high FGT inflammation by K-means clustering according to pro-inflammatory cytokine concentrations.
@article{Alisoltani2020,
abstract = {Background: Female genital tract (FGT) inflammation is an important risk factor for HIV acquisition. The FGT microbiome is closely associated with inflammatory profile; however, the relative importance of microbial activities has not been established. Since proteins are key elements representing actual microbial functions, this study utilized metaproteomics to evaluate the relationship between FGT microbial function and inflammation in 113 young and adolescent South African women at high risk of HIV infection. Women were grouped as having low, medium, or high FGT inflammation by K-means clustering according to pro-inflammatory cytokine concentrations.},
author = {Alisoltani, Arghavan and Manhanzva, Monalisa T. and Potgieter, Matthys and Balle, Christina and Bell, Liam and Ross, Elizabeth and Iranzadeh, Arash and du Plessis, Michelle and Radzey, Nina and McDonald, Zac and Calder, Bridget and Allali, Imane and Mulder, Nicola and Dabee, Smritee and Barnabas, Shaun and Gamieldien, Hoyam and Godzik, Adam and Blackburn, Jonathan M. and Tabb, David L. and Bekker, Linda-Gail and Jaspan, Heather B. and Passmore, Jo-Ann S. and Masson, Lindi},
doi = {10.1186/s40168-020-00932-8},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Alisoltani et al. - 2020 - Microbial function and genital inflammation in young South African women at high risk of HIV infection.pdf:pdf},
issn = {2049-2618},
journal = {Microbiome},
keywords = {Bioinformatics,Medical Microbiology,Microbial Ecology,Microbial Genetics and Genomics,Microbiology,OA,Virology,fund{\_}not{\_}ack,original},
mendeley-tags = {OA,fund{\_}not{\_}ack,original},
month = {dec},
number = {1},
pages = {165},
pmid = {33220709},
publisher = {BioMed Central},
title = {{Microbial function and genital inflammation in young South African women at high risk of HIV infection}},
url = {https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-020-00932-8},
volume = {8},
year = {2020}
}
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