GenGraph: a python module for the simple generation and manipulation of genome graphs. Ambler, J. M., Mulaudzi, S., & Mulder, N. BMC Bioinformatics, 20(1):519, dec, 2019.
GenGraph: a python module for the simple generation and manipulation of genome graphs [link]Paper  doi  abstract   bibtex   
As sequencing technology improves, the concept of a single reference genome is becoming increasingly restricting. In the case of Mycobacterium tuberculosis, one must often choose between using a genome that is closely related to the isolate, or one that is annotated in detail. One promising solution to this problem is through the graph based representation of collections of genomes as a single genome graph. Though there are currently a handful of tools that can create genome graphs and have demonstrated the advantages of this new paradigm, there still exists a need for flexible tools that can be used by researchers to overcome challenges in genomics studies.
@article{Ambler2019,
abstract = {As sequencing technology improves, the concept of a single reference genome is becoming increasingly restricting. In the case of Mycobacterium tuberculosis, one must often choose between using a genome that is closely related to the isolate, or one that is annotated in detail. One promising solution to this problem is through the graph based representation of collections of genomes as a single genome graph. Though there are currently a handful of tools that can create genome graphs and have demonstrated the advantages of this new paradigm, there still exists a need for flexible tools that can be used by researchers to overcome challenges in genomics studies.},
author = {Ambler, Jon Mitchell and Mulaudzi, Shandukani and Mulder, Nicola},
doi = {10.1186/s12859-019-3115-8},
issn = {1471-2105},
journal = {BMC Bioinformatics},
keywords = {OA,fund{\_}not{\_}ack,original},
mendeley-tags = {OA,fund{\_}not{\_}ack,original},
month = {dec},
number = {1},
pages = {519},
pmid = {31653197},
title = {{GenGraph: a python module for the simple generation and manipulation of genome graphs}},
url = {https://doi.org/10.1186/s12859-019-3115-8 https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-019-3115-8},
volume = {20},
year = {2019}
}

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