Executive functioning in school-aged children who were born very preterm or with extremely low birth weight in the 1990s. Anderson, P. J & Doyle, L. W Pediatrics, 114(1):50–7, July, 2004.
Executive functioning in school-aged children who were born very preterm or with extremely low birth weight in the 1990s. [link]Paper  abstract   bibtex   
OBJECTIVE: To determine the frequency, nature, and severity of executive dysfunction (EDF) at 8 years of age in extremely low birth weight (ELBW)/very preterm infants who were born in the 1990s, compared with normal birth weight (NBW) control subjects. METHODS: A geographically determined cohort study was conducted in Victoria, Australia. The ELBW/very preterm cohort comprised 298 consecutive survivors at 2 years of age who had gestational ages \textless28 completed weeks or birth weights \textless1000 g and were born during 1991-1992. The NBW cohort comprised 262 randomly selected children of birth weight \textgreater2499 g matched on date of birth, gender, ethnicity, and health insurance status. The participation rate was 92% (275 of 298) for the ELBW/very preterm cohort and 85% (223 of 262) for the NBW cohort. Cognitive and behavioral measures of executive functioning were administered. RESULTS: The ELBW/very preterm cohort exhibited significant EDF compared with their NBW peers in all areas assessed. The cognitive assessment revealed global impairment rather than deficits in specific executive domains. The ELBW/very preterm children also displayed more behavioral problems indicative of EDF than the NBW children. Severe impairments were exhibited in only a small minority of ELBW/very preterm children. No statistical conclusions were altered after adjustment for sociodemographic variables or when children with substantial neurosensory impairment were excluded. CONCLUSIONS: School-aged children who were born in the 1990s and were very preterm or had ELBW are at greater risk for developing EDF and require ongoing neuropsychological review throughout middle childhood.
@article{anderson_executive_2004,
	title = {Executive functioning in school-aged children who were born very preterm or with extremely low birth weight in the 1990s.},
	volume = {114},
	issn = {1098-4275},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/15231907},
	abstract = {OBJECTIVE: To determine the frequency, nature, and severity of executive dysfunction (EDF) at 8 years of age in extremely low birth weight (ELBW)/very preterm infants who were born in the 1990s, compared with normal birth weight (NBW) control subjects.

METHODS: A geographically determined cohort study was conducted in Victoria, Australia. The ELBW/very preterm cohort comprised 298 consecutive survivors at 2 years of age who had gestational ages {\textless}28 completed weeks or birth weights {\textless}1000 g and were born during 1991-1992. The NBW cohort comprised 262 randomly selected children of birth weight {\textgreater}2499 g matched on date of birth, gender, ethnicity, and health insurance status. The participation rate was 92\% (275 of 298) for the ELBW/very preterm cohort and 85\% (223 of 262) for the NBW cohort. Cognitive and behavioral measures of executive functioning were administered.

RESULTS: The ELBW/very preterm cohort exhibited significant EDF compared with their NBW peers in all areas assessed. The cognitive assessment revealed global impairment rather than deficits in specific executive domains. The ELBW/very preterm children also displayed more behavioral problems indicative of EDF than the NBW children. Severe impairments were exhibited in only a small minority of ELBW/very preterm children. No statistical conclusions were altered after adjustment for sociodemographic variables or when children with substantial neurosensory impairment were excluded.

CONCLUSIONS: School-aged children who were born in the 1990s and were very preterm or had ELBW are at greater risk for developing EDF and require ongoing neuropsychological review throughout middle childhood.},
	number = {1},
	urldate = {2015-05-26},
	journal = {Pediatrics},
	author = {Anderson, Peter J and Doyle, Lex W},
	month = jul,
	year = {2004},
	pmid = {15231907},
	keywords = {Child, Child Behavior Disorders, Cognition, Cognition Disorders, Cohort Studies, Developmental Disabilities, Female, Form Perception, Humans, Infant, Newborn, Infant, Premature, Infant, Very Low Birth Weight, Intelligence, Male, Memory, Neuropsychological Tests},
	pages = {50--7},
}

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