Single-cell laser ablation uncovers the blueprint of plant development. Anjam, M. S., Di Fino, L. M., Ma, X., & Marhavý, P. Trends in Plant Science, May, 2026.
Paper doi abstract bibtex Understanding how positional information within plant tissues shapes developmental programs in real time has long remained a challenge due to technical limitations in precisely accessing and manipulating defined cellular domains within complex tissues. Recent advances in single-cell laser ablation, particularly when combined with confocal microscopy, now allow precise spatiotemporal perturbation of selected cells. This technology has enabled researchers to dissect cellular functions, communication dynamics, and mechanical responses with unprecedented accuracy. Here, we review how laser ablation has emerged as a transformative approach in plant biology, from unraveling the signaling networks governing meristem maintenance and root patterning to modeling wound responses and immune activation.
@article{anjam_single-cell_2026,
title = {Single-cell laser ablation uncovers the blueprint of plant development},
issn = {1360-1385},
url = {https://www.sciencedirect.com/science/article/pii/S1360138526001329},
doi = {10.1016/j.tplants.2026.04.029},
abstract = {Understanding how positional information within plant tissues shapes developmental programs in real time has long remained a challenge due to technical limitations in precisely accessing and manipulating defined cellular domains within complex tissues. Recent advances in single-cell laser ablation, particularly when combined with confocal microscopy, now allow precise spatiotemporal perturbation of selected cells. This technology has enabled researchers to dissect cellular functions, communication dynamics, and mechanical responses with unprecedented accuracy. Here, we review how laser ablation has emerged as a transformative approach in plant biology, from unraveling the signaling networks governing meristem maintenance and root patterning to modeling wound responses and immune activation.},
urldate = {2026-05-29},
journal = {Trends in Plant Science},
author = {Anjam, Muhammad S. and Di Fino, Luciano Martín and Ma, Xuemin and Marhavý, Peter},
month = may,
year = {2026},
keywords = {mechanobiology, phytohormone crosstalk, single-cell ablation, tissue regeneration, wound signaling},
}
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