Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis. Annunziata, I., Patterson, A., Helton, D., Hu, H., Moshiach, S., Gomero, E., Nixon, R., & d’Azzo , A. Nature Communications, 4:ncomms3734, November, 2013.
Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis [link]Paper  doi  abstract   bibtex   
\textlessp\textgreater The enzyme NEU1 negatively regulates lysosomal exocytosis in various cell types. Annunziata et al. show that mice deficient in NEU1 display Alzheimer’s disease-like pathology and that direct brain administration of NEU1 reduces pathology in an Alzheimer’s disease…\textless/p\textgreater
@article{annunziata_lysosomal_2013,
	title = {Lysosomal {NEU1} deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis},
	volume = {4},
	copyright = {2013 Nature Publishing Group},
	issn = {2041-1723},
	url = {https://www.nature.com/articles/ncomms3734},
	doi = {10.1038/ncomms3734},
	abstract = {{\textless}p{\textgreater}
The enzyme NEU1 negatively regulates lysosomal exocytosis in various cell types. Annunziata \textit{et al.} show that mice deficient in NEU1 display Alzheimer’s disease-like pathology and that direct brain administration of NEU1 reduces pathology in an Alzheimer’s disease\…{\textless}/p{\textgreater}},
	language = {en},
	urldate = {2017-10-12},
	journal = {Nature Communications},
	author = {Annunziata, Ida and Patterson, Annette and Helton, Danielle and Hu, Huimin and Moshiach, Simon and Gomero, Elida and Nixon, Ralph and d’Azzo, Alessandra},
	month = nov,
	year = {2013},
	pages = {ncomms3734}
}

Downloads: 0