{"_id":"eopay78AFcZqGKyxB","bibbaseid":"anonymous-etiologyofinvasivecandidosisagentsinrussiaamulticenterepidemiologicalsurvey-2018","bibdata":{"bibtype":"article","type":"article","author":[{"propositions":[],"lastnames":["Vasilyeva"],"firstnames":["N.V."],"suffixes":[]},{"propositions":[],"lastnames":["Raush"],"firstnames":["E.R."],"suffixes":[]},{"propositions":[],"lastnames":["Rudneva"],"firstnames":["M.V."],"suffixes":[]},{"propositions":[],"lastnames":["Bogomolova"],"firstnames":["T.S."],"suffixes":[]},{"propositions":[],"lastnames":["Taraskina"],"firstnames":["A.E."],"suffixes":[]},{"propositions":[],"lastnames":["Fang"],"firstnames":["Y."],"suffixes":[]},{"propositions":[],"lastnames":["Zhang"],"firstnames":["F."],"suffixes":[]},{"propositions":[],"lastnames":["Klimko"],"firstnames":["N.N."],"suffixes":[]}],"title":"Etiology of invasive candidosis agents in Russia: a multicenter epidemiological survey","journal":"Frontiers of Medicine","year":"2018","volume":"12","number":"1","pages":"84-91","doi":"10.1007/s11684-017-0612-x","note":"cited By 3","url":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041368413&doi=10.1007%2fs11684-017-0612-x&partnerID=40&md5=40abd7727bade42e3097ccd0f5d3bd3c","affiliation":"Department of Medical Microbiology, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, 194291, Russian Federation; Kashkin Research Institute of Medical Mycology, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, 194291, Russian Federation; Sino-Russia Institute of Infection and Immunity, Department of Microbiology, Harbin Medical University, Harbin, 150086, China; Department of Clinical Mycology, Allergy and Immunology, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, 194291, Russian Federation","abstract":"A multicenter prospective epidemiological survey on the etiologic agents of invasive candidosis was conducted in Russia in the period of 2012–2014. Samples were collected from 284 patients with invasive candidosis and Candida species isolated by culture. The species were identified by DNA sequencing and MALDI-TOF massspectrometry. A total of 322 isolates were recovered, in which 96% of Сandida species belonged to six major species, namely, C. albicans (43.2%), C. parapsilosis (20.2%), C. glabrata (11.5%), C. tropicalis (9.6%), C. krusei (6.2%), and C. guilliermondii (5.3%). Most Candida species were isolated from blood samples (83.23%). Notably, the prevalence rate of C. albicans reduced from 52.38% to 32.79% (2012 vs. 2014) (P = 0.01) whereas that of non-C. albicans increased from 47.62% (2012) to 67.21% (2014) (P < 0.01). Species distribution differed among geographical regions; specifically, the prevalence rate of C. albicans as an etiologic agent of invasive candidosis in Siberian Federal region was significantly higher than that in other Federal regions. Results indicated a shift from C. albicans to non-C. albicans. Therefore, a detailed investigation on the contributing factors and appropriate treatment of invasive candidosis is needed. © 2018, Higher Education Press and Springer-Verlag GmbH Germany.","author_keywords":"Candida species; candidemia; etiology; invasive candidosis; MALDI-TOF mass-spectrometry; nosocomial; prevalence","funding_details":"National Natural Science Foundation of China81301703","key":"Vasilyeva201884","id":"Vasilyeva201884","bibbaseid":"anonymous-etiologyofinvasivecandidosisagentsinrussiaamulticenterepidemiologicalsurvey-2018","role":"author","urls":{"Paper":"https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041368413&doi=10.1007%2fs11684-017-0612-x&partnerID=40&md5=40abd7727bade42e3097ccd0f5d3bd3c"},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bio.pnpi.nrcki.ru/wp-content/uploads/2019/12/lmgch_2019_10.txt","dataSources":["87fXC3NAxFNMB5YTH"],"keywords":[],"search_terms":["etiology","invasive","candidosis","agents","russia","multicenter","epidemiological","survey"],"title":"Etiology of invasive candidosis agents in Russia: a multicenter epidemiological survey","year":2018}