@article{RN6096,
   title = {Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium},
   journal = {Neuro Oncol},
   volume = {20},
   number = {7},
   pages = {873-884},
   note = {1523-5866
GLASS Consortium
R01 CA188228/CA/NCI NIH HHS/United States
G0701018/MRC_/Medical Research Council/United Kingdom
G1100578/MRC_/Medical Research Council/United Kingdom
KLI 394/FWF_/Austrian Science Fund FWF/Austria
MR/N004272/1/MRC_/Medical Research Council/United Kingdom
R01 CA169316/CA/NCI NIH HHS/United States
P30 CA138292/CA/NCI NIH HHS/United States
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
England
2018/02/13
Neuro Oncol. 2018 Jun 18;20(7):873-884. doi: 10.1093/neuonc/noy020.},
   abstract = {Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and molecular subtypes of glioma at diagnosis. However, gliomas undergo significant cellular and molecular evolution during disease progression. We review the current knowledge on the genomic and epigenetic abnormalities in primary tumors and after disease recurrence, highlight the gaps in the literature, and elaborate on the need for a new multi-institutional effort to bridge these knowledge gaps and how the Glioma Longitudinal Analysis Consortium (GLASS) aims to systemically catalog the longitudinal changes in gliomas. The GLASS initiative will provide essential insights into the evolution of glioma toward a lethal phenotype, with the potential to reveal targetable vulnerabilities and, ultimately, improved outcomes for a patient population in need.},
   keywords = {Brain Neoplasms/genetics/*pathology/therapy
*Evolution, Molecular
Genomics
Glioma/genetics/*pathology/therapy
Humans
Longitudinal Studies},
   ISSN = {1522-8517 (Print)
1522-8517},
   DOI = {10.1093/neuonc/noy020},
   year = {2018},
   type = {Journal Article}
}

{"_id":"CRe9vnoSQT3gGfHak","bibbaseid":"anonymous-gliomathroughthelookingglassmolecularevolutionofdiffusegliomasandthegliomalongitudinalanalysisconsortium-2018","bibdata":{"bibtype":"article","type":"Journal Article","title":"Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium","journal":"Neuro Oncol","volume":"20","number":"7","pages":"873-884","note":"1523-5866 GLASS Consortium R01 CA188228/CA/NCI NIH HHS/United States G0701018/MRC_/Medical Research Council/United Kingdom G1100578/MRC_/Medical Research Council/United Kingdom KLI 394/FWF_/Austrian Science Fund FWF/Austria MR/N004272/1/MRC_/Medical Research Council/United Kingdom R01 CA169316/CA/NCI NIH HHS/United States P30 CA138292/CA/NCI NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review England 2018/02/13 Neuro Oncol. 2018 Jun 18;20(7):873-884. doi: 10.1093/neuonc/noy020.","abstract":"Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and molecular subtypes of glioma at diagnosis. However, gliomas undergo significant cellular and molecular evolution during disease progression. We review the current knowledge on the genomic and epigenetic abnormalities in primary tumors and after disease recurrence, highlight the gaps in the literature, and elaborate on the need for a new multi-institutional effort to bridge these knowledge gaps and how the Glioma Longitudinal Analysis Consortium (GLASS) aims to systemically catalog the longitudinal changes in gliomas. The GLASS initiative will provide essential insights into the evolution of glioma toward a lethal phenotype, with the potential to reveal targetable vulnerabilities and, ultimately, improved outcomes for a patient population in need.","keywords":"Brain Neoplasms/genetics/*pathology/therapy *Evolution, Molecular Genomics Glioma/genetics/*pathology/therapy Humans Longitudinal Studies","issn":"1522-8517 (Print) 1522-8517","doi":"10.1093/neuonc/noy020","year":"2018","bibtex":"@article{RN6096,\n title = {Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium},\n journal = {Neuro Oncol},\n volume = {20},\n number = {7},\n pages = {873-884},\n note = {1523-5866\nGLASS Consortium\nR01 CA188228/CA/NCI NIH HHS/United States\nG0701018/MRC_/Medical Research Council/United Kingdom\nG1100578/MRC_/Medical Research Council/United Kingdom\nKLI 394/FWF_/Austrian Science Fund FWF/Austria\nMR/N004272/1/MRC_/Medical Research Council/United Kingdom\nR01 CA169316/CA/NCI NIH HHS/United States\nP30 CA138292/CA/NCI NIH HHS/United States\nJournal Article\nResearch Support, N.I.H., Extramural\nResearch Support, Non-U.S. Gov't\nReview\nEngland\n2018/02/13\nNeuro Oncol. 2018 Jun 18;20(7):873-884. doi: 10.1093/neuonc/noy020.},\n abstract = {Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and molecular subtypes of glioma at diagnosis. However, gliomas undergo significant cellular and molecular evolution during disease progression. We review the current knowledge on the genomic and epigenetic abnormalities in primary tumors and after disease recurrence, highlight the gaps in the literature, and elaborate on the need for a new multi-institutional effort to bridge these knowledge gaps and how the Glioma Longitudinal Analysis Consortium (GLASS) aims to systemically catalog the longitudinal changes in gliomas. 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