Single-nucleotide polymorphism in a local population of Trichophyton rubrum. Medical Mycology, 56(1):125-128, 2018. cited By 0
Single-nucleotide polymorphism in a local population of Trichophyton rubrum [link]Paper  doi  abstract   bibtex   
Trichophyton rubrum is an important causative agent of superficial mycoses worldwide. To uncover a genetic composition of a local population of this fungus, we sequenced A7C99 6411 and A7C99 6714 loci, coding for hypothetical proteins and revealed two complex genotypes, differing by a single missense mutation in each locus. One of the two A7C99 6411/6714 genotypes was not found in tinea pedis cases and demonstrated mostly longer TRS-1 elements when compared to another genotype. Thus, we present a description of nucleotide polymorphism in protein-coding loci in T. rubrum and provide evidence for ecological preferences of T. rubrum genotypes at a local scale. © The Author 2017. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.

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