Discovery of New G-quadruplex Binding Chemotypes. a Ohnmacht, S., Varavipour, E., Nanjunda, R., Pazitna, I., Vita, G. D., Gunaratnam, M., Kumar, A., a Ismail, M., Boykin, D. W, Wilson, W D., & Neidle, S. Chemical communications (Cambridge, England), December, 2013. doi abstract bibtex We report here on the discovery and preliminary evaluation of a novel non-macrocyclic low molecular weight quadruplex-stabilizing chemotype. The lead compounds, based on a furan core, show high G-quadruplex stabilisation and selectivity as well as potent in vitro anti-proliferative activity.
@article{Ohnmacht2013,
title = {Discovery of New {{G-quadruplex}} Binding Chemotypes.},
author = {a Ohnmacht, Stephan and Varavipour, Ehsan and Nanjunda, Rupesh and Pazitna, Ingrida and Vita, Gloria Di and Gunaratnam, Mekala and Kumar, Arvind and a Ismail, Mohamed and Boykin, David W and Wilson, W David and Neidle, Stephen},
year = {2013},
month = dec,
journal = {Chemical communications (Cambridge, England)},
eprint = {24302123},
eprinttype = {pubmed},
pages = {1--4},
issn = {1364-548X},
doi = {10.1039/c3cc48616h},
abstract = {We report here on the discovery and preliminary evaluation of a novel non-macrocyclic low molecular weight quadruplex-stabilizing chemotype. The lead compounds, based on a furan core, show high G-quadruplex stabilisation and selectivity as well as potent in vitro anti-proliferative activity.},
pmid = {24302123},
keywords = {\#nosource}
}
Downloads: 0
{"_id":"ZvrmyLNKMQkxyab2X","bibbaseid":"aohnmacht-varavipour-nanjunda-pazitna-vita-gunaratnam-kumar-aismail-etal-discoveryofnewgquadruplexbindingchemotypes-2013","author_short":["a Ohnmacht, S.","Varavipour, E.","Nanjunda, R.","Pazitna, I.","Vita, G. D.","Gunaratnam, M.","Kumar, A.","a Ismail, M.","Boykin, D. W","Wilson, W D.","Neidle, S."],"bibdata":{"bibtype":"article","type":"article","title":"Discovery of New G-quadruplex Binding Chemotypes.","author":[{"propositions":["a"],"lastnames":["Ohnmacht"],"firstnames":["Stephan"],"suffixes":[]},{"propositions":[],"lastnames":["Varavipour"],"firstnames":["Ehsan"],"suffixes":[]},{"propositions":[],"lastnames":["Nanjunda"],"firstnames":["Rupesh"],"suffixes":[]},{"propositions":[],"lastnames":["Pazitna"],"firstnames":["Ingrida"],"suffixes":[]},{"propositions":[],"lastnames":["Vita"],"firstnames":["Gloria","Di"],"suffixes":[]},{"propositions":[],"lastnames":["Gunaratnam"],"firstnames":["Mekala"],"suffixes":[]},{"propositions":[],"lastnames":["Kumar"],"firstnames":["Arvind"],"suffixes":[]},{"propositions":["a"],"lastnames":["Ismail"],"firstnames":["Mohamed"],"suffixes":[]},{"propositions":[],"lastnames":["Boykin"],"firstnames":["David","W"],"suffixes":[]},{"propositions":[],"lastnames":["Wilson"],"firstnames":["W","David"],"suffixes":[]},{"propositions":[],"lastnames":["Neidle"],"firstnames":["Stephen"],"suffixes":[]}],"year":"2013","month":"December","journal":"Chemical communications (Cambridge, England)","eprint":"24302123","eprinttype":"pubmed","pages":"1–4","issn":"1364-548X","doi":"10.1039/c3cc48616h","abstract":"We report here on the discovery and preliminary evaluation of a novel non-macrocyclic low molecular weight quadruplex-stabilizing chemotype. The lead compounds, based on a furan core, show high G-quadruplex stabilisation and selectivity as well as potent in vitro anti-proliferative activity.","pmid":"24302123","keywords":"#nosource","bibtex":"@article{Ohnmacht2013,\n title = {Discovery of New {{G-quadruplex}} Binding Chemotypes.},\n author = {a Ohnmacht, Stephan and Varavipour, Ehsan and Nanjunda, Rupesh and Pazitna, Ingrida and Vita, Gloria Di and Gunaratnam, Mekala and Kumar, Arvind and a Ismail, Mohamed and Boykin, David W and Wilson, W David and Neidle, Stephen},\n year = {2013},\n month = dec,\n journal = {Chemical communications (Cambridge, England)},\n eprint = {24302123},\n eprinttype = {pubmed},\n pages = {1--4},\n issn = {1364-548X},\n doi = {10.1039/c3cc48616h},\n abstract = {We report here on the discovery and preliminary evaluation of a novel non-macrocyclic low molecular weight quadruplex-stabilizing chemotype. The lead compounds, based on a furan core, show high G-quadruplex stabilisation and selectivity as well as potent in vitro anti-proliferative activity.},\n pmid = {24302123},\n keywords = {\\#nosource}\n}\n\n","author_short":["a Ohnmacht, S.","Varavipour, E.","Nanjunda, R.","Pazitna, I.","Vita, G. D.","Gunaratnam, M.","Kumar, A.","a Ismail, M.","Boykin, D. W","Wilson, W D.","Neidle, S."],"key":"Ohnmacht2013","id":"Ohnmacht2013","bibbaseid":"aohnmacht-varavipour-nanjunda-pazitna-vita-gunaratnam-kumar-aismail-etal-discoveryofnewgquadruplexbindingchemotypes-2013","role":"author","urls":{},"keyword":["#nosource"],"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/f/F7MP3WMbDyMbtFCC8/My Library.bib","dataSources":["4i5C7S78DvJNsaHyg"],"keywords":["#nosource"],"search_terms":["discovery","new","quadruplex","binding","chemotypes","a ohnmacht","varavipour","nanjunda","pazitna","vita","gunaratnam","kumar","a ismail","boykin","wilson","neidle"],"title":"Discovery of New G-quadruplex Binding Chemotypes.","year":2013}