Sensitivity of epicardial electrical markers to acute ischemia detection. Aras, K., Burton, B., Swenson, D., & MacLeod, R. j-JE, 47(6):836--841, 2014.
bibtex   
@Article{RSM:Ara2014,
  author =       "K.K. Aras and B.M. Burton and D.J. Swenson and R.S. MacLeod",
  title =        "Sensitivity of epicardial electrical markers to acute
                 ischemia detection.",
  journal =      j-JE,
  volume =       47,
  number =       6,
  year =         "2014",
  pages =        "836--841",
  robnote =      "INTRODUCTION: We hypothesize that electrocardiographic
                 measurements from the intramyocardial space contain more
                 sensitive markers of ischemia than those detectable on the
                 epicardium. The goal of this study was to evaluate
                 different electrical markers for their potential to detect
                 the earliest phases of acute myocardial ischemia. METHODS:
                 We conducted acute ischemia studies in open chest animal,
                 by creating finely controlled demand or supply ischemic
                 episodes and recording intramyocardial and epicardial
                 potentials. RESULTS: Under the conditions of mild
                 perfusion deficit, acute ischemia induced changes in the T
                 wave that were larger and could be detected earlier on the
                 epicardial surface than ST-segment changes. CONCLUSIONS:
                 Our findings indicate that in the setting of very acute
                 ischemia, epicardial T waves have higher sensitivity to
                 mild degrees of acute ischemia than epicardial ST
                 potentials. These results suggest that changes in the T
                 wave shape may augment shifts in ST segments to improve
                 ECG based localization of ischemia.",
  bibdate =      "Sun Oct 12 09:13:39 2014",
  pmcid =        "PMC4252649",
}

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