Sensitivity of epicardial electrical markers to acute ischemia detection. Aras, K., Burton, B., Swenson, D., & MacLeod, R. j-JE, 47(6):836--841, 2014. bibtex @Article{RSM:Ara2014,
author = "K.K. Aras and B.M. Burton and D.J. Swenson and R.S. MacLeod",
title = "Sensitivity of epicardial electrical markers to acute
ischemia detection.",
journal = j-JE,
volume = 47,
number = 6,
year = "2014",
pages = "836--841",
robnote = "INTRODUCTION: We hypothesize that electrocardiographic
measurements from the intramyocardial space contain more
sensitive markers of ischemia than those detectable on the
epicardium. The goal of this study was to evaluate
different electrical markers for their potential to detect
the earliest phases of acute myocardial ischemia. METHODS:
We conducted acute ischemia studies in open chest animal,
by creating finely controlled demand or supply ischemic
episodes and recording intramyocardial and epicardial
potentials. RESULTS: Under the conditions of mild
perfusion deficit, acute ischemia induced changes in the T
wave that were larger and could be detected earlier on the
epicardial surface than ST-segment changes. CONCLUSIONS:
Our findings indicate that in the setting of very acute
ischemia, epicardial T waves have higher sensitivity to
mild degrees of acute ischemia than epicardial ST
potentials. These results suggest that changes in the T
wave shape may augment shifts in ST segments to improve
ECG based localization of ischemia.",
bibdate = "Sun Oct 12 09:13:39 2014",
pmcid = "PMC4252649",
}
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