Genome-wide inference of natural selection on human transcription factor binding sites. Arbiza, L., Gronau, I., Aksoy, B. A., Hubisz, M. J., Gulko, B., Keinan, A., & Siepel, A. Nature Genetics, 45(7):723–729, July, 2013. Number: 7 Publisher: Nature Publishing Group![Genome-wide inference of natural selection on human transcription factor binding sites [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Adam Siepel and colleagues find that natural selection has exerted a significant influence on transcription factor binding sites in the human lineage using a new probabilistic method, INSIGHT. They analyzed whole-genome sequences from 54 individuals, as well as from several non-human primates, combined with chromatin immunoprecipitation and sequencing data sets to identify transcription factor binding sites and evidence of selection.
@article{arbiza_genome-wide_2013,
title = {Genome-wide inference of natural selection on human transcription factor binding sites},
volume = {45},
copyright = {2013 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.},
issn = {1546-1718},
url = {https://www.nature.com/articles/ng.2658},
doi = {10.1038/ng.2658},
abstract = {Adam Siepel and colleagues find that natural selection has exerted a significant influence on transcription factor binding sites in the human lineage using a new probabilistic method, INSIGHT. They analyzed whole-genome sequences from 54 individuals, as well as from several non-human primates, combined with chromatin immunoprecipitation and sequencing data sets to identify transcription factor binding sites and evidence of selection.},
language = {en},
number = {7},
urldate = {2020-06-22},
journal = {Nature Genetics},
author = {Arbiza, Leonardo and Gronau, Ilan and Aksoy, Bulent A. and Hubisz, Melissa J. and Gulko, Brad and Keinan, Alon and Siepel, Adam},
month = jul,
year = {2013},
note = {Number: 7
Publisher: Nature Publishing Group},
pages = {723--729},
}
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