Role of the host genetic variability in the influenza A virus susceptibility. Arcanjo, Carolina, A., Mazzocco, G., de Oliveira, Fabiana, S., Plewczynski, D., & Radomski, J. P. Acta Biochimica Polonica, 61(3):403--419, 2014. abstract bibtex The aftermath of influenza infection is determined by a complex set of host-pathogen interactions, where genomic variability on both viral and host sides influences the final outcome. Although there exists large body of literature describing influenza virus variability, only a very small fraction covers the issue of host variance. The goal of this review is to explore the variability of host genes responsible for host-pathogen interactions, paying particular attention to genes responsible for the presence of sialylated glycans in the host endothelial membrane, mucus, genes used by viral immune escape mechanisms, and genes particularly expressed after vaccination, since they are more likely to have a direct influence on the infection outcome.
@article{ arcanjo_role_2014,
title = {Role of the host genetic variability in the influenza {A} virus susceptibility},
volume = {61},
issn = {1734-154X},
abstract = {The aftermath of influenza infection is determined by a complex set of host-pathogen interactions, where genomic variability on both viral and host sides influences the final outcome. Although there exists large body of literature describing influenza virus variability, only a very small fraction covers the issue of host variance. The goal of this review is to explore the variability of host genes responsible for host-pathogen interactions, paying particular attention to genes responsible for the presence of sialylated glycans in the host endothelial membrane, mucus, genes used by viral immune escape mechanisms, and genes particularly expressed after vaccination, since they are more likely to have a direct influence on the infection outcome.},
language = {eng},
number = {3},
journal = {Acta Biochimica Polonica},
author = {Arcanjo, Ana Carolina and Mazzocco, Giovanni and de Oliveira, Silviene Fabiana and Plewczynski, Dariusz and Radomski, Jan P.},
year = {2014},
pmid = {25184407},
keywords = {Genetic Predisposition to Disease, Genetic Variation, Host-Pathogen Interactions, Humans, Influenza A virus, Influenza, Human},
pages = {403--419}
}
Downloads: 0
{"_id":"t9wyr8T4QM33dnfMQ","bibbaseid":"arcanjo-carolina-mazzocco-denbspoliveira-fabiana-plewczynski-radomski-roleofthehostgeneticvariabilityintheinfluenzaavirussusceptibility-2014","downloads":0,"creationDate":"2015-09-07T06:52:48.747Z","title":"Role of the host genetic variability in the influenza A virus susceptibility","author_short":["Arcanjo","Carolina, A.","Mazzocco, G.","de<nbsp>Oliveira","Fabiana, S.","Plewczynski, D.","Radomski, J.<nbsp>P."],"year":2014,"bibtype":"article","biburl":"http://bibbase.org/zotero/vdec","bibdata":{"abstract":"The aftermath of influenza infection is determined by a complex set of host-pathogen interactions, where genomic variability on both viral and host sides influences the final outcome. Although there exists large body of literature describing influenza virus variability, only a very small fraction covers the issue of host variance. The goal of this review is to explore the variability of host genes responsible for host-pathogen interactions, paying particular attention to genes responsible for the presence of sialylated glycans in the host endothelial membrane, mucus, genes used by viral immune escape mechanisms, and genes particularly expressed after vaccination, since they are more likely to have a direct influence on the infection outcome.","author":["Arcanjo","Carolina, Ana","Mazzocco, Giovanni","de Oliveira","Fabiana, Silviene","Plewczynski, Dariusz","Radomski, Jan P."],"author_short":["Arcanjo","Carolina, A.","Mazzocco, G.","de<nbsp>Oliveira","Fabiana, S.","Plewczynski, D.","Radomski, J.<nbsp>P."],"bibtex":"@article{ arcanjo_role_2014,\n title = {Role of the host genetic variability in the influenza {A} virus susceptibility},\n volume = {61},\n issn = {1734-154X},\n abstract = {The aftermath of influenza infection is determined by a complex set of host-pathogen interactions, where genomic variability on both viral and host sides influences the final outcome. Although there exists large body of literature describing influenza virus variability, only a very small fraction covers the issue of host variance. The goal of this review is to explore the variability of host genes responsible for host-pathogen interactions, paying particular attention to genes responsible for the presence of sialylated glycans in the host endothelial membrane, mucus, genes used by viral immune escape mechanisms, and genes particularly expressed after vaccination, since they are more likely to have a direct influence on the infection outcome.},\n language = {eng},\n number = {3},\n journal = {Acta Biochimica Polonica},\n author = {Arcanjo, Ana Carolina and Mazzocco, Giovanni and de Oliveira, Silviene Fabiana and Plewczynski, Dariusz and Radomski, Jan P.},\n year = {2014},\n pmid = {25184407},\n keywords = {Genetic Predisposition to Disease, Genetic Variation, Host-Pathogen Interactions, Humans, Influenza A virus, Influenza, Human},\n pages = {403--419}\n}","bibtype":"article","id":"arcanjo_role_2014","issn":"1734-154X","journal":"Acta Biochimica Polonica","key":"arcanjo_role_2014","keywords":"Genetic Predisposition to Disease, Genetic Variation, Host-Pathogen Interactions, Humans, Influenza A virus, Influenza, Human","language":"eng","number":"3","pages":"403--419","pmid":"25184407","title":"Role of the host genetic variability in the influenza A virus susceptibility","type":"article","volume":"61","year":"2014","bibbaseid":"arcanjo-carolina-mazzocco-denbspoliveira-fabiana-plewczynski-radomski-roleofthehostgeneticvariabilityintheinfluenzaavirussusceptibility-2014","role":"author","urls":{},"keyword":["Genetic Predisposition to Disease","Genetic Variation","Host-Pathogen Interactions","Humans","Influenza A virus","Influenza","Human"],"downloads":0},"search_terms":["role","host","genetic","variability","influenza","virus","susceptibility","arcanjo","carolina","mazzocco","de<nbsp>oliveira","fabiana","plewczynski","radomski"],"keywords":["genetic predisposition to disease","genetic variation","host-pathogen interactions","humans","influenza a virus","influenza","human"],"authorIDs":[],"dataSources":["JnJ2Whzgn25T7zFga"]}