Case report of early signs of aortic stenosis decompensation detected via ambient sensor-derived digital biomarkers. Arenja, N., Schütz, N., Buluschek, P., Nef, T., & Saner, H. European Heart Journal - Case Reports, 9(2):ytae655, 12, 2024.
Case report of early signs of aortic stenosis decompensation detected via ambient sensor-derived digital biomarkers [link]Paper  doi  abstract   bibtex   
Aortic stenosis is a progressive condition with a grim prognosis, underscoring the importance of timely intervention to prevent decompensation. Home monitoring systems, particularly those utilizing ambient sensors, offer promise in detecting early signs of deterioration.We present the case of an 89-year-old woman who was asymptomatic but monitored using such a system prior to experiencing acute decompensation. Key clinical indicators, including increased night-time heart rate, respiration rate, toss and turns in bed, and nocturia, were observed several months before hospitalization. Additionally, reduced physical activity and increased toilet visits were noted.These findings highlight the potential of ambient sensor systems in identifying pre-clinical stages of cardiac decompensation, especially in severe aortic stenosis cases. Integrating ambient sensor systems into routine clinical practice holds promise for enhancing proactive management strategies and reducing adverse outcomes associated with cardiovascular disease progression.
@article{10.1093/ehjcr/ytae655,
  author={Arenja, Nisha and Schütz, Narayan and Buluschek, Philipp and 
Nef, Tobias and Saner, Hugo},
  title={Case report of early signs of aortic stenosis decompensation 
detected via ambient sensor-derived digital biomarkers},
  journal={European Heart Journal - Case Reports},
  volume={9},
  number={2},
  pages={ytae655},
  year={2024},
  month={12},
  abstract={Aortic stenosis is a progressive condition with a grim prognosis,
underscoring the importance of timely intervention to prevent 
decompensation. Home monitoring systems, particularly those utilizing 
ambient sensors, offer promise in detecting early signs of deterioration.We 
present the case of an 89-year-old woman who was asymptomatic but 
monitored using such a system prior to experiencing acute decompensation. 
Key clinical indicators, including increased night-time heart rate, respiration
rate, toss and turns in bed, and nocturia, were observed several months 
before hospitalization. Additionally, reduced physical activity and increased 
toilet visits were noted.These findings highlight the potential of ambient 
sensor systems in identifying pre-clinical stages of cardiac decompensation, 
especially in severe aortic stenosis cases. Integrating ambient sensor 
systems into routine clinical practice holds promise for enhancing proactive 
management strategies and reducing adverse outcomes associated with 
cardiovascular disease progression.},
  issn={2514-2119},
  doi={10.1093/ehjcr/ytae655},
  url={https://doi.org/10.1093/ehjcr/ytae655},
  
eprint={https://academic.oup.com/ehjcr/article-pdf/9/2/ytae655/61051247/
ytae655.pdf}
}

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