Experimental assessment of a novel robotically-driven endoscopic capsule compared to traditional colonoscopy. Arezzo, A., Menciassi, A., Valdastri, P., Ciuti, G., Lucarini, G., Salerno, M., Di Natali, C., Verra, M., Dario, P., & Morino, M. Digestive and Liver Disease: Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 45(8):657–662, August, 2013. 00000 ZSCC: NoCitationData[s0]
doi  abstract   bibtex   
BACKGROUND: Despite colonoscopy represents the conventional diagnostic tool for colorectal pathology, its undeniable discomfort reduces compliance to screening programmes. AIMS: To evaluate feasibility and accuracy of a novel robotically-driven magnetic capsule for colonoscopy as compared to the traditional technique. METHODS: Eleven experts and eleven trainees performed complete colonoscopy by robotic magnetic capsule and by conventional colonoscope in a phantom ex vivo model (artificially clean swine bowel). Feasibility, overall accuracy to detect installed pins, procedure elapsed time and intuitiveness were measured for both techniques in both operator groups. RESULTS: Complete colonoscopy was feasible in all cases with both techniques. Overall 544/672 pins (80.9%) were detected by experimental capsule procedure, while 591/689 pins (85.8%) were detected within conventional colonoscopy procedure (P=ns), thus establishing non-inferiority. With the experimental capsule procedure, experts detected 74.2% of pins vs. 87.6% detected by trainees (P\textless0.0001). Overall time to complete colon inspection by robotic capsule was significantly higher than by conventional colonoscopy (556±188s vs. 194±158s, respectively; P=0.0001). CONCLUSION: With the limitations represented by an ex vivo setting (artificially clean swine bowel and the absence of peristalsis), colonoscopy by this novel robotically-driven capsule resulted feasible and showed adequate accuracy compared to conventional colonoscopy.
@article{arezzo_experimental_2013,
	title = {Experimental assessment of a novel robotically-driven endoscopic capsule compared to traditional colonoscopy},
	volume = {45},
	issn = {1878-3562},
	doi = {10/f2mqsf},
	abstract = {BACKGROUND: Despite colonoscopy represents the conventional diagnostic tool for colorectal pathology, its undeniable discomfort reduces compliance to screening programmes.
AIMS: To evaluate feasibility and accuracy of a novel robotically-driven magnetic capsule for colonoscopy as compared to the traditional technique.
METHODS: Eleven experts and eleven trainees performed complete colonoscopy by robotic magnetic capsule and by conventional colonoscope in a phantom ex vivo model (artificially clean swine bowel). Feasibility, overall accuracy to detect installed pins, procedure elapsed time and intuitiveness were measured for both techniques in both operator groups.
RESULTS: Complete colonoscopy was feasible in all cases with both techniques. Overall 544/672 pins (80.9\%) were detected by experimental capsule procedure, while 591/689 pins (85.8\%) were detected within conventional colonoscopy procedure (P=ns), thus establishing non-inferiority. With the experimental capsule procedure, experts detected 74.2\% of pins vs. 87.6\% detected by trainees (P{\textless}0.0001). Overall time to complete colon inspection by robotic capsule was significantly higher than by conventional colonoscopy (556±188s vs. 194±158s, respectively; P=0.0001).
CONCLUSION: With the limitations represented by an ex vivo setting (artificially clean swine bowel and the absence of peristalsis), colonoscopy by this novel robotically-driven capsule resulted feasible and showed adequate accuracy compared to conventional colonoscopy.},
	language = {eng},
	number = {8},
	journal = {Digestive and Liver Disease: Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver},
	author = {Arezzo, Alberto and Menciassi, Arianna and Valdastri, Pietro and Ciuti, Gastone and Lucarini, Gioia and Salerno, Marco and Di Natali, Christian and Verra, Mauro and Dario, Paolo and Morino, Mario},
	month = aug,
	year = {2013},
	pmid = {23453360},
	note = {00000 
ZSCC: NoCitationData[s0] },
	keywords = {Animals, Capsule Endoscopes, Capsule Endoscopy, Capsule endoscopy, Colon, Colonoscopes, Colonoscopy, Colorectal Neoplasms, Colorectal cancer screening, Endoscopic robotic platform, Equipment Design, Feasibility Studies, Humans, In Vitro Techniques, Magnetics, Phantoms, Imaging, Predictive Value of Tests, Robotics, Sensitivity and Specificity, Swine, Unread},
	pages = {657--662},
}

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