@article{
 title = {Recombination yet inefficient selection along the Drosophila melanogaster subgroup's fourth chromosome},
 type = {article},
 year = {2010},
 identifiers = {[object Object]},
 volume = {27},
 id = {4ff07564-0e17-3a82-bb1b-8b9f8341807c},
 created = {2022-07-26T06:03:57.411Z},
 file_attached = {false},
 profile_id = {8c659bfd-01d3-3429-846f-d37b18791820},
 group_id = {25fd0bf4-15fa-3f6b-b2ca-7f7583fa2975},
 last_modified = {2022-07-26T06:03:57.411Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {A central goal of evolutionary genetics is an understanding of the forces responsible for the observed variation, both within and between species. Theoretical and empirical work have demonstrated that genetic recombination contributes to this variation by breaking down linkage between nucleotide sites, thus allowing them to behave independently and for selective forces to act efficiently on them. The Drosophila fourth chromosome, which is believed to experience no-or very low-rates of recombination has been an important model for investigating these effects. Despite previous efforts, central questions regarding the extent of recombination and the predominant modes of selection acting on it remain open. In order to more comprehensively test hypotheses regarding recombination and its potential influence on selection along the fourth chromosome, we have resequenced regions from most of its genes from Drosophila melanogaster, D. simulans, and D. yakuba. These data, along with available outgroup sequence, demonstrate that recombination is low but significantly greater than zero for the three species. Despite there being recombination, there is strong evidence that its frequency is low enough to have rendered selection relatively inefficient. The signatures of relaxed constraint can be detected at both the level of polymorphism and divergence. © The Author 2009.},
 bibtype = {article},
 author = {Arguello, J. Roman and Zhang, Yue and Kado, Tomoyuki and Fan, Chuanzhu and Zhao, Ruoping and Innan, Hideki and Wang, Wen and Long, Manyuan},
 journal = {Molecular Biology and Evolution},
 number = {4}
}

{"_id":"CKMjjHPrJp76jhP6b","bibbaseid":"arguello-zhang-kado-fan-zhao-innan-wang-long-recombinationyetinefficientselectionalongthedrosophilamelanogastersubgroupsfourthchromosome-2010","author_short":["Arguello, J., R.","Zhang, Y.","Kado, T.","Fan, C.","Zhao, R.","Innan, H.","Wang, W.","Long, M."],"bibdata":{"title":"Recombination yet inefficient selection along the Drosophila melanogaster subgroup's fourth chromosome","type":"article","year":"2010","identifiers":"[object Object]","volume":"27","id":"4ff07564-0e17-3a82-bb1b-8b9f8341807c","created":"2022-07-26T06:03:57.411Z","file_attached":false,"profile_id":"8c659bfd-01d3-3429-846f-d37b18791820","group_id":"25fd0bf4-15fa-3f6b-b2ca-7f7583fa2975","last_modified":"2022-07-26T06:03:57.411Z","read":false,"starred":false,"authored":false,"confirmed":false,"hidden":false,"private_publication":false,"abstract":"A central goal of evolutionary genetics is an understanding of the forces responsible for the observed variation, both within and between species. Theoretical and empirical work have demonstrated that genetic recombination contributes to this variation by breaking down linkage between nucleotide sites, thus allowing them to behave independently and for selective forces to act efficiently on them. The Drosophila fourth chromosome, which is believed to experience no-or very low-rates of recombination has been an important model for investigating these effects. Despite previous efforts, central questions regarding the extent of recombination and the predominant modes of selection acting on it remain open. In order to more comprehensively test hypotheses regarding recombination and its potential influence on selection along the fourth chromosome, we have resequenced regions from most of its genes from Drosophila melanogaster, D. simulans, and D. yakuba. These data, along with available outgroup sequence, demonstrate that recombination is low but significantly greater than zero for the three species. Despite there being recombination, there is strong evidence that its frequency is low enough to have rendered selection relatively inefficient. The signatures of relaxed constraint can be detected at both the level of polymorphism and divergence. © The Author 2009.","bibtype":"article","author":"Arguello, J. Roman and Zhang, Yue and Kado, Tomoyuki and Fan, Chuanzhu and Zhao, Ruoping and Innan, Hideki and Wang, Wen and Long, Manyuan","journal":"Molecular Biology and Evolution","number":"4","bibtex":"@article{\n title = {Recombination yet inefficient selection along the Drosophila melanogaster subgroup's fourth chromosome},\n type = {article},\n year = {2010},\n identifiers = {[object Object]},\n volume = {27},\n id = {4ff07564-0e17-3a82-bb1b-8b9f8341807c},\n created = {2022-07-26T06:03:57.411Z},\n file_attached = {false},\n profile_id = {8c659bfd-01d3-3429-846f-d37b18791820},\n group_id = {25fd0bf4-15fa-3f6b-b2ca-7f7583fa2975},\n last_modified = {2022-07-26T06:03:57.411Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n private_publication = {false},\n abstract = {A central goal of evolutionary genetics is an understanding of the forces responsible for the observed variation, both within and between species. Theoretical and empirical work have demonstrated that genetic recombination contributes to this variation by breaking down linkage between nucleotide sites, thus allowing them to behave independently and for selective forces to act efficiently on them. The Drosophila fourth chromosome, which is believed to experience no-or very low-rates of recombination has been an important model for investigating these effects. Despite previous efforts, central questions regarding the extent of recombination and the predominant modes of selection acting on it remain open. In order to more comprehensively test hypotheses regarding recombination and its potential influence on selection along the fourth chromosome, we have resequenced regions from most of its genes from Drosophila melanogaster, D. simulans, and D. yakuba. These data, along with available outgroup sequence, demonstrate that recombination is low but significantly greater than zero for the three species. Despite there being recombination, there is strong evidence that its frequency is low enough to have rendered selection relatively inefficient. The signatures of relaxed constraint can be detected at both the level of polymorphism and divergence. © The Author 2009.},\n bibtype = {article},\n author = {Arguello, J. Roman and Zhang, Yue and Kado, Tomoyuki and Fan, Chuanzhu and Zhao, Ruoping and Innan, Hideki and Wang, Wen and Long, Manyuan},\n journal = {Molecular Biology and Evolution},\n number = {4}\n}","author_short":["Arguello, J., R.","Zhang, Y.","Kado, T.","Fan, C.","Zhao, R.","Innan, H.","Wang, W.","Long, M."],"biburl":"https://bibbase.org/service/mendeley/8c659bfd-01d3-3429-846f-d37b18791820","bibbaseid":"arguello-zhang-kado-fan-zhao-innan-wang-long-recombinationyetinefficientselectionalongthedrosophilamelanogastersubgroupsfourthchromosome-2010","role":"author","urls":{},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/service/mendeley/8c659bfd-01d3-3429-846f-d37b18791820","dataSources":["PMuSoECgPtHvvZi6t"],"keywords":[],"search_terms":["recombination","inefficient","selection","along","drosophila","melanogaster","subgroup","fourth","chromosome","arguello","zhang","kado","fan","zhao","innan","wang","long"],"title":"Recombination yet inefficient selection along the Drosophila melanogaster subgroup's fourth chromosome","year":2010}