Mechanical unfolding of long human telomeric RNA (TERRA).

Mechanical unfolding of long human telomeric RNA (TERRA). Arias-Gonzalez, J. R., Garavís, M., Bocanegra, R., Herrero-Galán, E., Villasante, A., Gonzalez, C., & González, C. Chemical communications (Cambridge, England), 49(57):6397–6399, June, 2013. tex.ids= garavisMechanicalUnfoldingLong2013, garavisMechanicalUnfoldingLong2013a

Paper doi abstract bibtex

We report the first single molecule investigation of TERRA molecules. By using optical-tweezers and other biophysical techniques, we have found that long RNA constructions of up to 25 GGGUUA repeats form higher order structures comprised of single parallel G-quadruplex blocks, which unfold at lower forces than their DNA counterparts.

@article{arias-gonzalez_mechanical_2013,
	title = {Mechanical unfolding of long human telomeric {RNA} ({TERRA}).},
	volume = {49},
	issn = {1364-548X},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/23748212 http://pubs.rsc.org/en/Content/ArticleLanding/2013/CC/c3cc42981d},
	doi = {10.1039/c3cc42981d},
	abstract = {We report the first single molecule investigation of TERRA molecules. By using optical-tweezers and other biophysical techniques, we have found that long RNA constructions of up to 25 GGGUUA repeats form higher order structures comprised of single parallel G-quadruplex blocks, which unfold at lower forces than their DNA counterparts.},
	number = {57},
	journal = {Chemical communications (Cambridge, England)},
	author = {Arias-Gonzalez, J. Ricardo and Garavís, Miguel and Bocanegra, Rebeca and Herrero-Galán, Elías and Villasante, Alfredo and Gonzalez, Carlos and González, Carlos},
	month = jun,
	year = {2013},
	pmid = {23748212},
	note = {tex.ids= garavisMechanicalUnfoldingLong2013, garavisMechanicalUnfoldingLong2013a},
	pages = {6397--6399},
}

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