Effects of Allium sativum (garlic) on systolic and diastolic blood pressure in patients with essential hypertension. Ashraf, R., Khan, R. A., Ashraf, I., & Qureshi, A. A. Pakistan Journal of Pharmaceutical Sciences, 26(5):859–863, September, 2013.
abstract   bibtex   
The present study evaluated the effects of garlic on blood pressure in patients with essential hypertension. Patients (n=210) with stage 1 essential hypertension were divided into 7 groups named as A, B, C, D, E, F and G. Each group comprised of 30 patients. Each patient in group A, B, C, D and E has received garlic tablets at the dose of 300/mg. 600/mg, 900/mg, 1200/mg and 1500/mg in divided doses per day respectively for 24 weeks while Group F & group G were given tablet atenolol and placebo respectively. Blood pressure readings were recorded at weeks 0, 12 and 24. Present study showed significant decrease in both Systolic and Diastolic blood pressure in both dose and duration dependent manner. In each garlic treated group, significant reduction in SBP and DBP (p<0.005) were observed when compared with atenolol (P<0.005) and placebo.
@article{ashraf_effects_2013,
	title = {Effects of {Allium} sativum (garlic) on systolic and diastolic blood pressure in patients with essential hypertension},
	volume = {26},
	issn = {1011-601X},
	abstract = {The present study evaluated the effects of garlic on blood pressure in patients with essential hypertension. Patients (n=210) with stage 1 essential hypertension were divided into 7 groups named as A, B, C, D, E, F and G. Each group comprised of 30 patients. Each patient in group A, B, C, D and E has received garlic tablets at the dose of 300/mg. 600/mg, 900/mg, 1200/mg and 1500/mg in divided doses per day respectively for 24 weeks while Group F \& group G were given tablet atenolol and placebo respectively. Blood pressure readings were recorded at weeks 0, 12 and 24. Present study showed significant decrease in both Systolic and Diastolic blood pressure in both dose and duration dependent manner. In each garlic treated group, significant reduction in SBP and DBP (p\&lt;0.005) were observed when compared with atenolol (P\&lt;0.005) and placebo.},
	language = {eng},
	number = {5},
	journal = {Pakistan Journal of Pharmaceutical Sciences},
	author = {Ashraf, Rizwan and Khan, Rafeeq Alam and Ashraf, Imran and Qureshi, Absar A.},
	month = sep,
	year = {2013},
	pmid = {24035939},
	keywords = {Adult, Aged, Analysis of Variance, Antihypertensive Agents, Blood Pressure, Diastole, Female, Garlic, Humans, Hypertension, Male, Middle Aged, Pakistan, Phytotherapy, Plant Extracts, Plants, Medicinal, Single-Blind Method, Systole, Time Factors, Treatment Outcome, Young Adult},
	pages = {859--863},
}

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