Application of spin echoes in the regime of weak dephasing to <i>T</i> $_{\textrm{1}}$ -mapping of the lung: Application of Spin Echoes in the Regime of Weak Dephasing. Assländer, J., Glaser, S. J., & Hennig, J. Magnetic Resonance in Medicine, 79(2):960–967, February, 2018. ![Application of spin echoes in the regime of weak dephasing to <i>T</i> $_{\textrm{1}}$ -mapping of the lung: Application of Spin Echoes in the Regime of Weak Dephasing [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Purpose: This work presents an approach to mapping the entire lung’s proton density and T1 within a single breath-hold and analyzes the apparent T1 when exciting with a spin echo generating pulse in comparison to a standard gradient echo acquisition. Methods: An inversion-recovery SNAPSHOT-FLASH sequence with a stack-of-stars k-space readout with a golden angle increment was modified to use a spin echo generating radiofrequencypulse for excitation. Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR-Fingerprinting. Results: The feasibility of acquiring quantitative maps of the entire lung with a resolution of 5 Â 5 Â 10 mm within 7.5 s is demonstrated. It is shown that the proposed spin echo forming radiofrequency-pulse increases the apparent proton density compared to a rectangular pulse. Further, the apparent T1 is reduced in the spin echo case compared to the gradient echo sequence. Conclusion: The proposed spin echo based method results in T1 maps that are comparable to the ones that were acquired with ultra-short echo time sequences elsewhere. The T1 shortening is believed to originate from increased signal contributions of the extra vascular compartment, which has a short T2Ã and T1. Magn Reson Med 000:000–000, 2017. VC 2017 International Society for Magnetic Resonance in Medicine.
@article{asslander_application_2018,
title = {Application of spin echoes in the regime of weak dephasing to \textit{{T}} $_{\textrm{1}}$ -mapping of the lung: {Application} of {Spin} {Echoes} in the {Regime} of {Weak} {Dephasing}},
volume = {79},
issn = {07403194},
shorttitle = {Application of spin echoes in the regime of weak dephasing to \textit{{T}} $_{\textrm{1}}$ -mapping of the lung},
url = {http://doi.wiley.com/10.1002/mrm.26719},
doi = {10.1002/mrm.26719},
abstract = {Purpose: This work presents an approach to mapping the entire lung’s proton density and T1 within a single breath-hold and analyzes the apparent T1 when exciting with a spin echo generating pulse in comparison to a standard gradient echo acquisition.
Methods: An inversion-recovery SNAPSHOT-FLASH sequence with a stack-of-stars k-space readout with a golden angle increment was modified to use a spin echo generating radiofrequencypulse for excitation. Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR-Fingerprinting.
Results: The feasibility of acquiring quantitative maps of the entire lung with a resolution of 5 Â 5 Â 10 mm within 7.5 s is demonstrated. It is shown that the proposed spin echo forming radiofrequency-pulse increases the apparent proton density compared to a rectangular pulse. Further, the apparent T1 is reduced in the spin echo case compared to the gradient echo sequence.
Conclusion: The proposed spin echo based method results in T1 maps that are comparable to the ones that were acquired with ultra-short echo time sequences elsewhere. The T1 shortening is believed to originate from increased signal contributions of the extra vascular compartment, which has a short T2Ã and T1. Magn Reson Med 000:000–000, 2017. VC 2017 International Society for Magnetic Resonance in Medicine.},
language = {en},
number = {2},
urldate = {2021-02-12},
journal = {Magnetic Resonance in Medicine},
author = {Assländer, Jakob and Glaser, Steffen J. and Hennig, Jürgen},
month = feb,
year = {2018},
pages = {960--967},
}
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Methods: An inversion-recovery SNAPSHOT-FLASH sequence with a stack-of-stars k-space readout with a golden angle increment was modified to use a spin echo generating radiofrequencypulse for excitation. Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR-Fingerprinting. Results: The feasibility of acquiring quantitative maps of the entire lung with a resolution of 5 Â 5 Â 10 mm within 7.5 s is demonstrated. It is shown that the proposed spin echo forming radiofrequency-pulse increases the apparent proton density compared to a rectangular pulse. Further, the apparent T1 is reduced in the spin echo case compared to the gradient echo sequence. Conclusion: The proposed spin echo based method results in T1 maps that are comparable to the ones that were acquired with ultra-short echo time sequences elsewhere. 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Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR-Fingerprinting.\nResults: The feasibility of acquiring quantitative maps of the entire lung with a resolution of 5 Â 5 Â 10 mm within 7.5 s is demonstrated. It is shown that the proposed spin echo forming radiofrequency-pulse increases the apparent proton density compared to a rectangular pulse. Further, the apparent T1 is reduced in the spin echo case compared to the gradient echo sequence.\nConclusion: The proposed spin echo based method results in T1 maps that are comparable to the ones that were acquired with ultra-short echo time sequences elsewhere. The T1 shortening is believed to originate from increased signal contributions of the extra vascular compartment, which has a short T2Ã and T1. Magn Reson Med 000:000–000, 2017. 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