Unclad optical fiber tips for plasmonic biosensing of heart failure biomarker. Assunção, A. S., Vidal, M., Loyez, M., Caucheteur, C., Costa, F. M., Mesquita-Bastos, J., Pereira, S. O., & Leitão, C. In European Workshop on Optical Fibre Sensors, EWOFS 2023, 2023. Teledyne SP Devices, SPIE.
doi  abstract   bibtex   
Plasmonic optical fiber sensors have been investigated for biosensing purposes as they provide miniaturized devices with fast, label-free and highly sensitive responses. This study explores gold-coated optical fiber tip sensors, based on multimode fibers of 200 and 600 µm core diameters, for the detection of the heart failure biomarker N-terminal pro-Brain natriuretic peptide (NT-proBNP). The obtained results demonstrated that the 200 µm core tip reached the highest refractometric sensitivity, between 1158.54 and 2750.34 nm/RIU, and that both sensors responded to NT-proBNP concentrations in a range that included the values of clinical interest for the diagnosis of this cardiovascular disease, which correspond to 0.125 ng/mL and 0.300 ng/mL.
@inproceedings{ORBi-001ad6d0-3567-435a-91ec-4efc63cafc06,
	AUTHOR = {Assunção, Ana Sofia and Vidal, Miguel and Loyez, Médéric and Caucheteur, Christophe and Costa, Florinda M. and Mesquita-Bastos, José and Pereira, Sónia O. and Leitão, Cátia},
	TITLE = {Unclad optical fiber tips for plasmonic biosensing of heart failure biomarker},
	LANGUAGE = {Anglais},
	YEAR = {2023},
	DOI = {10.1117/12.2678368},
	PUBLISHER = {SPIE},
	BOOKTITLE = {European Workshop on Optical Fibre Sensors, EWOFS 2023},
	LOCATION = {Mons, Belgium},
	ABSTRACT = {Plasmonic optical fiber sensors have been investigated for biosensing purposes as they provide miniaturized devices with fast, label-free and highly sensitive responses. This study explores gold-coated optical fiber tip sensors, based on multimode fibers of 200 and 600 µm core diameters, for the detection of the heart failure biomarker N-terminal pro-Brain natriuretic peptide (NT-proBNP). The obtained results demonstrated that the 200 µm core tip reached the highest refractometric sensitivity, between 1158.54 and 2750.34 nm/RIU, and that both sensors responded to NT-proBNP concentrations in a range that included the values of clinical interest for the diagnosis of this cardiovascular disease, which correspond to 0.125 ng/mL and 0.300 ng/mL.},
	ORGANIZATION = {Teledyne SP Devices}
}

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