Electron capture dissociation in a radio frequency ion trap. Baba, T., Hashimoto, Y., Hasegawa, H., Hirabayashi, A., & Waki, I. Analytical chemistry, 76(15):4263-6, 8, 2004.
Electron capture dissociation in a radio frequency ion trap. [pdf]Paper  Electron capture dissociation in a radio frequency ion trap. [link]Website  abstract   bibtex   
We report on the first evidence of electron capture dissociation (ECD) in a radio frequency (rf) ion trap. Peptide ions, [substance P]2+, trapped in a two-dimensional, linear rf ion trap were cleaved by electrons injected along the central axis of the trap. Along the axis, the rf field component was zero and a magnetic field of 50 mT was applied. This electron injection scheme keeps the energy of the electrons below 1 eV, preventing them from heating by the rf field. The present ECD efficiency is approximately 4% by irradiation of electron current of 0.2 microA for 80 ms. ECD in rf traps may open high-throughput and low-cost ECD applications to obtain molecular structure information complementary to collision-induced dissociation.

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