Blood-Brain Barrier Leakage in Early Alzheimer Disease, Response. Backes, W. H., Van Osch, M. J., Van de Haar, H. J., & Jansen, J. F. Radiology, 282(3):924-25, 2017.
Blood-Brain Barrier Leakage in Early Alzheimer Disease, Response [link]Paper  doi  abstract   bibtex   
Dr Lecler and colleagues comment on theoretical aspects of the kinetic modeling used in our study on BBB leakage measurements (1). Models employed in imaging studies are frequently discussed and should always be carefully designed, validated, and tested for reproducibility (2). Therefore, we are happy to respond to these comments.
@article{RN238,
   author = {Backes, W. H. and Van Osch, M. J. and Van de Haar, H. J. and Jansen, J. F.},
   title = {Blood-Brain Barrier Leakage in Early Alzheimer Disease, Response},
   journal = {Radiology},
   volume = {282},
   number = {3},
   pages = {924-25},
   abstract = {Dr Lecler and colleagues comment on theoretical aspects of the kinetic modeling used in our study on BBB leakage measurements (1). 
Models employed in imaging studies are frequently discussed and should always be carefully designed, validated, and tested for reproducibility
(2). Therefore, we are happy to respond to these comments.},
   keywords = {Aged
Aged, 80 and over
Alzheimer Disease/*diagnostic imaging/*pathology
Blood Volume
Blood-Brain Barrier/*diagnostic imaging/*pathology
Case-Control Studies
Contrast Media
Female
Humans
Magnetic Resonance Imaging/*methods
Male
Middle Aged
Pilot Projects},
   ISSN = {1527-1315 (Electronic)
0033-8419 (Linking)},
   DOI = {10.1148/radiol.2017162578},
   url = {https://pubs.rsna.org/doi/10.1148/radiol.2017162578},
   year = {2017},
   type = {Journal Article}
}

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