@article{RN207,
   author = {Barendse, E. M. and Schreuder, L. J. and Thoonen, G. and Hendriks, M. P. H. and Kessels, R. P. C. and Backes, W. H. and Aldenkamp, A. P. and Jansen, J. F. A.},
   title = {Working memory network alterations in high-functioning adolescents with an autism spectrum disorder},
   journal = {Psychiatry Clin Neurosci},
   volume = {72},
   number = {2},
   pages = {73-83},
   note = {Barendse, Evelien M
Schreuder, Lisanne J
Thoonen, Geert
Hendriks, Marc P H
Kessels, Roy P C
Backes, Walter H
Aldenkamp, Albert P
Jansen, Jacobus F A
eng
Australia
2017/09/05 06:00
Psychiatry Clin Neurosci. 2018 Feb;72(2):73-83. doi: 10.1111/pcn.12602. Epub 2017 Oct 3.},
   abstract = {AIM: People with autism spectrum disorder (ASD) typically have deficits in the working memory (WM) system. WM is found to be an essential chain in successfully navigating in the social world. We hypothesize that brain networks for WM have an altered network integrity in ASD compared to controls. METHODS: Thirteen adolescents (one female) with autistic disorder (n = 1), Asperger's disorder (n = 7), or pervasive developmental disorder not otherwise specified (n = 5), and 13 typically developing healthy control adolescents (one female) participated in this study. Functional magnetic resonance imaging (MRI) was performed using an n-back task and in resting state. RESULTS: The analysis of the behavioral data revealed deficits in WM performance in ASD, but only when tested to the limit. Adolescents with ASD showed lower binary global efficiency in the WM network than the healthy control group with n-back and resting-state data. This correlated with diagnostic scores for total problems, reciprocity, and language. CONCLUSION: Adolescents with higher-functioning autism have difficulty with the WM system, which is typically compensated. Functional MRI markers of brain network organization in ASD are related to characteristics of autism as represented in diagnostic scores. Therefore, functional MRI provides neuronal correlates for memory difficulties in adolescents with ASD.},
   keywords = {Adolescent
Asperger Syndrome/diagnostic imaging/physiopathology
Autism Spectrum Disorder/diagnostic imaging/*physiopathology
Cerebral Cortex/diagnostic imaging/*physiopathology
Child
Female
Functional Neuroimaging/*methods
Humans
Magnetic Resonance Imaging
Male
Memory, Short-Term/*physiology
Nerve Net/diagnostic imaging/*physiopathology
autism spectrum disorder
functional magnetic resonance imaging
higher functioning
network analysis
working memory},
   ISSN = {1440-1819 (Electronic)
1323-1316 (Linking)},
   DOI = {10.1111/pcn.12602},
   url = {http://www.ncbi.nlm.nih.gov/pubmed/28869354
https://onlinelibrary.wiley.com/doi/full/10.1111/pcn.12602},
   year = {2018},
   type = {Journal Article}
}

{"_id":"xTnWnowm6jDtgcLFK","bibbaseid":"barendse-schreuder-thoonen-hendriks-kessels-backes-aldenkamp-jansen-workingmemorynetworkalterationsinhighfunctioningadolescentswithanautismspectrumdisorder-2018","downloads":0,"creationDate":"2018-08-03T14:29:50.035Z","title":"Working memory network alterations in high-functioning adolescents with an autism spectrum disorder","author_short":["Barendse, E. M.","Schreuder, L. J.","Thoonen, G.","Hendriks, M. P. H.","Kessels, R. P. C.","Backes, W. H.","Aldenkamp, A. P.","Jansen, J. F. A."],"year":2018,"bibtype":"article","biburl":"https://raw.githubusercontent.com/jansenjfa1/bibbase.github.io/master/jansenjfa.bib","bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Barendse"],"firstnames":["E.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Schreuder"],"firstnames":["L.","J."],"suffixes":[]},{"propositions":[],"lastnames":["Thoonen"],"firstnames":["G."],"suffixes":[]},{"propositions":[],"lastnames":["Hendriks"],"firstnames":["M.","P.","H."],"suffixes":[]},{"propositions":[],"lastnames":["Kessels"],"firstnames":["R.","P.","C."],"suffixes":[]},{"propositions":[],"lastnames":["Backes"],"firstnames":["W.","H."],"suffixes":[]},{"propositions":[],"lastnames":["Aldenkamp"],"firstnames":["A.","P."],"suffixes":[]},{"propositions":[],"lastnames":["Jansen"],"firstnames":["J.","F.","A."],"suffixes":[]}],"title":"Working memory network alterations in high-functioning adolescents with an autism spectrum disorder","journal":"Psychiatry Clin Neurosci","volume":"72","number":"2","pages":"73-83","note":"Barendse, Evelien M Schreuder, Lisanne J Thoonen, Geert Hendriks, Marc P H Kessels, Roy P C Backes, Walter H Aldenkamp, Albert P Jansen, Jacobus F A eng Australia 2017/09/05 06:00 Psychiatry Clin Neurosci. 2018 Feb;72(2):73-83. doi: 10.1111/pcn.12602. Epub 2017 Oct 3.","abstract":"AIM: People with autism spectrum disorder (ASD) typically have deficits in the working memory (WM) system. WM is found to be an essential chain in successfully navigating in the social world. We hypothesize that brain networks for WM have an altered network integrity in ASD compared to controls. METHODS: Thirteen adolescents (one female) with autistic disorder (n = 1), Asperger's disorder (n = 7), or pervasive developmental disorder not otherwise specified (n = 5), and 13 typically developing healthy control adolescents (one female) participated in this study. Functional magnetic resonance imaging (MRI) was performed using an n-back task and in resting state. RESULTS: The analysis of the behavioral data revealed deficits in WM performance in ASD, but only when tested to the limit. Adolescents with ASD showed lower binary global efficiency in the WM network than the healthy control group with n-back and resting-state data. This correlated with diagnostic scores for total problems, reciprocity, and language. CONCLUSION: Adolescents with higher-functioning autism have difficulty with the WM system, which is typically compensated. Functional MRI markers of brain network organization in ASD are related to characteristics of autism as represented in diagnostic scores. Therefore, functional MRI provides neuronal correlates for memory difficulties in adolescents with ASD.","keywords":"Adolescent Asperger Syndrome/diagnostic imaging/physiopathology Autism Spectrum Disorder/diagnostic imaging/*physiopathology Cerebral Cortex/diagnostic imaging/*physiopathology Child Female Functional Neuroimaging/*methods Humans Magnetic Resonance Imaging Male Memory, Short-Term/*physiology Nerve Net/diagnostic imaging/*physiopathology autism spectrum disorder functional magnetic resonance imaging higher functioning network analysis working memory","issn":"1440-1819 (Electronic) 1323-1316 (Linking)","doi":"10.1111/pcn.12602","url":"http://www.ncbi.nlm.nih.gov/pubmed/28869354 https://onlinelibrary.wiley.com/doi/full/10.1111/pcn.12602","year":"2018","bibtex":"@article{RN207,\n author = {Barendse, E. M. and Schreuder, L. J. and Thoonen, G. and Hendriks, M. P. H. and Kessels, R. P. C. and Backes, W. H. and Aldenkamp, A. P. and Jansen, J. F. A.},\n title = {Working memory network alterations in high-functioning adolescents with an autism spectrum disorder},\n journal = {Psychiatry Clin Neurosci},\n volume = {72},\n number = {2},\n pages = {73-83},\n note = {Barendse, Evelien M\nSchreuder, Lisanne J\nThoonen, Geert\nHendriks, Marc P H\nKessels, Roy P C\nBackes, Walter H\nAldenkamp, Albert P\nJansen, Jacobus F A\neng\nAustralia\n2017/09/05 06:00\nPsychiatry Clin Neurosci. 2018 Feb;72(2):73-83. doi: 10.1111/pcn.12602. Epub 2017 Oct 3.},\n abstract = {AIM: People with autism spectrum disorder (ASD) typically have deficits in the working memory (WM) system. WM is found to be an essential chain in successfully navigating in the social world. We hypothesize that brain networks for WM have an altered network integrity in ASD compared to controls. METHODS: Thirteen adolescents (one female) with autistic disorder (n = 1), Asperger's disorder (n = 7), or pervasive developmental disorder not otherwise specified (n = 5), and 13 typically developing healthy control adolescents (one female) participated in this study. Functional magnetic resonance imaging (MRI) was performed using an n-back task and in resting state. RESULTS: The analysis of the behavioral data revealed deficits in WM performance in ASD, but only when tested to the limit. Adolescents with ASD showed lower binary global efficiency in the WM network than the healthy control group with n-back and resting-state data. This correlated with diagnostic scores for total problems, reciprocity, and language. CONCLUSION: Adolescents with higher-functioning autism have difficulty with the WM system, which is typically compensated. Functional MRI markers of brain network organization in ASD are related to characteristics of autism as represented in diagnostic scores. Therefore, functional MRI provides neuronal correlates for memory difficulties in adolescents with ASD.},\n keywords = {Adolescent\nAsperger Syndrome/diagnostic imaging/physiopathology\nAutism Spectrum Disorder/diagnostic imaging/*physiopathology\nCerebral Cortex/diagnostic imaging/*physiopathology\nChild\nFemale\nFunctional Neuroimaging/*methods\nHumans\nMagnetic Resonance Imaging\nMale\nMemory, Short-Term/*physiology\nNerve Net/diagnostic imaging/*physiopathology\nautism spectrum disorder\nfunctional magnetic resonance imaging\nhigher functioning\nnetwork analysis\nworking memory},\n ISSN = {1440-1819 (Electronic)\n1323-1316 (Linking)},\n DOI = {10.1111/pcn.12602},\n url = {http://www.ncbi.nlm.nih.gov/pubmed/28869354\nhttps://onlinelibrary.wiley.com/doi/full/10.1111/pcn.12602},\n year = {2018},\n type = {Journal Article}\n}\n\n","author_short":["Barendse, E. M.","Schreuder, L. J.","Thoonen, G.","Hendriks, M. P. H.","Kessels, R. P. C.","Backes, W. H.","Aldenkamp, A. P.","Jansen, J. F. A."],"key":"RN207","id":"RN207","bibbaseid":"barendse-schreuder-thoonen-hendriks-kessels-backes-aldenkamp-jansen-workingmemorynetworkalterationsinhighfunctioningadolescentswithanautismspectrumdisorder-2018","role":"author","urls":{"Paper":"http://www.ncbi.nlm.nih.gov/pubmed/28869354 https://onlinelibrary.wiley.com/doi/full/10.1111/pcn.12602"},"keyword":["Adolescent Asperger Syndrome/diagnostic imaging/physiopathology Autism Spectrum Disorder/diagnostic imaging/*physiopathology Cerebral Cortex/diagnostic imaging/*physiopathology Child Female Functional Neuroimaging/*methods Humans Magnetic Resonance Imaging Male Memory","Short-Term/*physiology Nerve Net/diagnostic imaging/*physiopathology autism spectrum disorder functional magnetic resonance imaging higher functioning network analysis working memory"],"metadata":{"authorlinks":{"jansen, j":"https://www.jansenjfa.com/publications/"}},"downloads":0,"html":""},"search_terms":["working","memory","network","alterations","high","functioning","adolescents","autism","spectrum","disorder","barendse","schreuder","thoonen","hendriks","kessels","backes","aldenkamp","jansen"],"keywords":["adolescent asperger syndrome/diagnostic imaging/physiopathology autism spectrum disorder/diagnostic imaging/*physiopathology cerebral cortex/diagnostic imaging/*physiopathology child female functional neuroimaging/*methods humans magnetic resonance imaging male memory","short-term/*physiology nerve net/diagnostic imaging/*physiopathology autism spectrum disorder functional magnetic resonance imaging higher functioning network analysis working memory"],"authorIDs":["59aae01e5ead235c6f00001d","5df1707557cfb4de0100001d","5e024e386ffa15df0100007a","5e47cbe8af70c7de0100001a","5e4ea88f64b624de01000110","5e685fc7149172de01000144","9uYiZAT4SGYEdwuhG","CHX5tw5dNmS7tFMt9","DoNKbgB55xkR6SehT","FEbMpouv9cRyJBZv3","GtL5d4iFpEuoJacN7","H6wbK4u5jYRFL8LDs","Jeci2sNzJiMSDeJvc","QqoDaykDZWJd9YuAu","RLbGKAvkbQAw2q2pz","TCejZCDssndxpTcJg","TEAWLnKpXtQE8hs6C","dR2ye6bifAsonnNMz","eJ9fizm2KNxBgiNfF","gxe8DkJ5qKbznZgZq","hGdeHv63Gb3m6CybW","hShritfXo7Lzr2RkJ","jDvmx9aE5aohaf7P7","rQrciQZhPyL9ovwM8","ryLRyF5HAWnpncbbr","sFGhcvCCManvCwLHz","zTR82AHQxLXLWt4wi"],"dataSources":["TCkfRWJAZvbLAZi29"]}