The SUR2 gene of Arabidopsis thaliana encodes the cytochrome P450 CYP83B1, a modulator of auxin homeostasis. Barlier, I., Kowalczyk, M., Marchant, A., Ljung, K., Bhalerao, R., Bennett, M., Sandberg, G., & Bellini, C. Proceedings of the National Academy of Sciences, 97(26):14819–14824, December, 2000. Publisher: National Academy of Sciences Section: Biological Sciences
The SUR2 gene of Arabidopsis thaliana encodes the cytochrome P450 CYP83B1, a modulator of auxin homeostasis [link]Paper  doi  abstract   bibtex   
Genetic screens have been performed to identify mutants with altered auxin homeostasis in Arabidopsis. A tagged allele of the auxin-overproducing mutant sur2 was identified within a transposon mutagenized population. The SUR2 gene was cloned and shown to encode the CYP83B1 protein, which belongs to the large family of the P450-dependent monooxygenases. SUR2 expression is up-regulated in sur1 mutants and induced by exogenous auxin in the wild type. Analysis of indole-3-acetic acid (IAA) synthesis and metabolism in sur2 plants indicates that the mutation causes a conditional increase in the pool size of IAA through up-regulation of IAA synthesis.
@article{barlier_sur2_2000,
	title = {The {SUR2} gene of {Arabidopsis} thaliana encodes the cytochrome {P450} {CYP83B1}, a modulator of auxin homeostasis},
	volume = {97},
	copyright = {Copyright © 2000, The National Academy of Sciences},
	issn = {0027-8424, 1091-6490},
	url = {https://www.pnas.org/content/97/26/14819},
	doi = {10/c36wb6},
	abstract = {Genetic screens have been performed to identify mutants with altered auxin homeostasis in Arabidopsis. A tagged allele of the auxin-overproducing mutant sur2 was identified within a transposon mutagenized population. The SUR2 gene was cloned and shown to encode the CYP83B1 protein, which belongs to the large family of the P450-dependent monooxygenases. SUR2 expression is up-regulated in sur1 mutants and induced by exogenous auxin in the wild type. Analysis of indole-3-acetic acid (IAA) synthesis and metabolism in sur2 plants indicates that the mutation causes a conditional increase in the pool size of IAA through up-regulation of IAA synthesis.},
	language = {en},
	number = {26},
	urldate = {2021-11-08},
	journal = {Proceedings of the National Academy of Sciences},
	author = {Barlier, Isabelle and Kowalczyk, Mariusz and Marchant, Alan and Ljung, Karin and Bhalerao, Rishikesh and Bennett, Malcolm and Sandberg, Goeran and Bellini, Catherine},
	month = dec,
	year = {2000},
	pmid = {11114200},
	note = {Publisher: National Academy of Sciences
Section: Biological Sciences},
	keywords = {metabolism},
	pages = {14819--14824},
}

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